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South Carolina

$149+ Cheap flights from Odessa, TX to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — CHS
ago. 5 — ago. 121
mar. 8/5
mar. 8/12
1 adult, Economy
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Cheap flight deals from Odessa to South Carolina

Keep the following information in mind while searching for Odessa to South Carolina flight deals. Data was last updated julio 31, 2025.

Round-trip from

$297
(American Airlines)

One-way from

$149
(American Airlines)
From Odessa to South Carolina
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One-way flight from Odessa to South Carolina
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Find flight deals from Odessa to South Carolina

Cheapest flights from Odessa to South Carolina
Explore the most affordable flight options available from Odessa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/17:36 amMAF - MYR
1 stop7h 46mAmerican Airlines
vie. 9/57:00 amMYR - MAF
1 stop7h 59mAmerican Airlines
Deal found 7/29$297
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/277:36 amMAF - CLT
1 stop5h 09mAmerican Airlines
mié. 9/31:49 pmCLT - MAF
1 stop4h 58mAmerican Airlines
Deal found 7/30$297
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/2712:31 pmMAF - CLT
2 stops9h 50mDelta
mié. 9/36:00 amCLT - MAF
2 stops11h 37mDelta
Deal found 7/30$307
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/165:30 amMAF - MYR
2 stops8h 43mDelta
mar. 8/196:00 amMYR - MAF
2 stops11h 37mDelta
Deal found 7/28$382
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/57:00 amMAF - CLT
2 stops10h 53mUnited Airlines
dom. 9/77:00 amCLT - MAF
1 stop5h 15mUnited Airlines
Deal found 7/31$413
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/305:00 amMAF - SAV
1 stop7h 30mAmerican Airlines
mié. 8/67:20 amSAV - MAF
1 stop7h 42mAmerican Airlines
Deal found 7/30$635
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/305:30 amMAF - SAV
2 stops8h 35mDelta
mié. 8/68:20 amSAV - MAF
2 stops9h 12mDelta
Deal found 7/30$645
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/164:00 pmMAF - MYR
3 stops21h 35mUnited Airlines
mar. 8/1912:47 pmMYR - MAF
2 stops11h 18mUnited Airlines
Deal found 7/30$657
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/25:40 pmMAF - CLT
1 stop4h 35mSouthwest
dom. 8/102:55 pmCLT - MAF
2 stops10h 00mSouthwest
Deal found 7/31$710

Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from Odessa to South Carolina that are best for you.

Fly from

Odessa

Fly to

South Carolina

Route

Depart

Return

Price

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

lun. 9/1

7:36 am-4:22 pm

1 stop7h 46m

Myrtle Beach Intl

vie. 9/5

7:00 am-1:59 pm

1 stop7h 59m

$297

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

mié. 8/27

7:36 am-1:45 pm

1 stop5h 09m

Charlotte Douglas

mié. 9/3

1:49 pm-5:47 pm

1 stop4h 58m

$297

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

mié. 8/27

12:31 pm-11:21 pm

2 stops9h 50m

Charlotte Douglas

mié. 9/3

6:00 am-4:37 pm

2 stops11h 37m

$307

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

sáb. 8/16

5:30 am-3:13 pm

2 stops8h 43m

Myrtle Beach Intl

mar. 8/19

6:00 am-4:37 pm

2 stops11h 37m

$382

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

vie. 9/5

7:00 am-6:53 pm

2 stops10h 53m

Charlotte Douglas

dom. 9/7

7:00 am-11:15 am

1 stop5h 15m

$413

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

sáb. 8/16

4:00 pm-2:35 pm

3 stops21h 35m

Myrtle Beach Intl

mar. 8/19

12:47 pm-11:05 pm

2 stops11h 18m

$657

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

mié. 8/27

6:33 pm-12:40 am

1 stop5h 07m

$149

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

mié. 8/27

5:30 am-12:59 pm

2 stops6h 29m

$154

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

vie. 9/12

11:17 am-11:09 pm

2 stops10h 52m

$154

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

jue. 8/28

9:50 am-5:35 pm

2 stops6h 45m

$255

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 11 results
1
2

Best time to book a flight from Odessa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated julio 31, 2025.
Read reviews from past customers who have flown Alaska Airlines, Southwest, and Delta from Odessa to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Southwest
8.0
Very good
4,246 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Delta
8.0
Very good
7,981 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
United Airlines
7.4
Good
8,900 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.

Related info for your journey

Find useful and relevant information for your journey from Odessa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Odessa to South Carolina one-way?

    One-way options have recently been found by users for as low as $149 on American Airlines. Other airlines that offer cheap prices include Delta from $154 and Southwest from $255 one-way.

  • What are the most popular routes from Odessa to South Carolina?

    While some choose either Midland Intl - Myrtle Beach Intl or Midland Intl - Savannah/Hilton Head, Midland Intl - Charlotte Douglas is the most popular route from Odessa to South Carolina.

  • Can I find deals for flights from Odessa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Odessa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to South Carolina.

  • Can I find deals for business class flights from Odessa to South Carolina?

    Yes. Cheapflights offers flight deals from Odessa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Odessa to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Odessa to South Carolina (average of $217). Flying from Odessa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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