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South Carolina

$279+ Cheap flights from Odessa, TX to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — CHS
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheap flight deals from Odessa to South Carolina

Keep the following information in mind while searching for Odessa to South Carolina flight deals. Data was last updated April 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$279
(American Airlines)
Provider with most accurate pricing for Midland Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Midland Intl-Myrtle Beach Intl flights.
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From Odessa to South Carolina
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Find flight deals from Odessa to South Carolina

Cheapest flights from Odessa to South Carolina
Explore the most affordable flight options available from Odessa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/72:30 pmMAF - CLT
1 stop7h 04mAmerican Airlines
Tue 8/123:05 pmCLT - MAF
1 stop5h 40mAmerican Airlines
Deal found 4/28$279
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/75:30 amMAF - CLT
2 stops11h 55mDelta
Tue 8/125:30 amCLT - MAF
2 stops7h 23mDelta
Deal found 4/28$289
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/235:30 amMAF - MYR
2 stops12h 35mDelta
Fri 7/253:59 pmMYR - MAF
2 stops9h 00mDelta
Deal found 4/29$311
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/157:41 amMAF - MYR
1 stop7h 42mAmerican Airlines
Mon 8/185:03 pmMYR - MAF
1 stop6h 51mAmerican Airlines
Deal found 4/29$317
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2912:39 pmMAF - SAV
2 stops10h 22mDelta
Tue 6/312:28 pmSAV - MAF
2 stops12h 34mDelta
Deal found 4/28$321
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/77:00 amMAF - CLT
1 stop8h 00mUnited Airlines
Tue 8/121:50 pmCLT - MAF
2 stops10h 25mUnited Airlines
Deal found 4/28$364
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/195:45 amMAF - CLT
1 stop8h 05mSouthwest
Thu 6/263:40 pmCLT - MAF
1 stop8h 15mSouthwest
Deal found 4/29$399
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:00 amMAF - SAV
1 stop8h 09mUnited Airlines
Sat 5/177:00 amSAV - MAF
1 stop8h 13mUnited Airlines
Deal found 4/28$427
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/298:26 pmMAF - SAV
1 stop17h 41mAmerican Airlines
Tue 6/33:52 pmSAV - MAF
1 stop5h 02mAmerican Airlines
Deal found 4/29$551
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/235:00 amMAF - MYR
2 stops8h 35mUnited Airlines
Fri 7/252:47 pmMYR - MAF
3 stops32h 07mUnited Airlines
Deal found 4/29$630

Cheapflights Fare Finder

Customize your flight search to find flights from Odessa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Odessa to South Carolina that are best for you.

Fly from

Odessa

Fly to

South Carolina

Route

Depart

Return

Price

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

Thu 8/7

2:30 pm-10:34 pm

1 stop7h 04m

Charlotte Douglas

Tue 8/12

3:05 pm-7:45 pm

1 stop5h 40m

$279

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

Thu 8/7

5:30 am-6:25 pm

2 stops11h 55m

Charlotte Douglas

Tue 8/12

5:30 am-11:53 am

2 stops7h 23m

$289

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

Wed 7/23

5:30 am-7:05 pm

2 stops12h 35m

Myrtle Beach Intl

Fri 7/25

3:59 pm-11:59 pm

2 stops9h 00m

$311

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

Fri 8/15

7:41 am-4:23 pm

1 stop7h 42m

Myrtle Beach Intl

Mon 8/18

5:03 pm-10:54 pm

1 stop6h 51m

$317

MidlandSavannah

MAF - SAV

MAFSAV

Midland Intl

Thu 5/29

12:39 pm-12:01 am

2 stops10h 22m

Savannah/Hilton Head

Tue 6/3

12:28 pm-12:02 am

2 stops12h 34m

$321

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

Thu 8/7

7:00 am-4:00 pm

1 stop8h 00m

Charlotte Douglas

Tue 8/12

1:50 pm-11:15 pm

2 stops10h 25m

$364

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

Thu 6/19

5:45 am-2:50 pm

1 stop8h 05m

Charlotte Douglas

Thu 6/26

3:40 pm-10:55 pm

1 stop8h 15m

$399

MidlandSavannah

MAF - SAV

MAFSAV

Midland Intl

Tue 5/13

6:00 am-3:09 pm

1 stop8h 09m

Savannah/Hilton Head

Sat 5/17

7:00 am-2:13 pm

1 stop8h 13m

$427

MidlandSavannah

MAF - SAV

MAFSAV

Midland Intl

Thu 5/29

8:26 pm-3:07 pm

1 stop17h 41m

Savannah/Hilton Head

Tue 6/3

3:52 pm-7:54 pm

1 stop5h 02m

$551

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

Wed 7/23

5:00 am-2:35 pm

2 stops8h 35m

Myrtle Beach Intl

Fri 7/25

2:47 pm-9:54 pm

3 stops32h 07m

$630

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Best time to book a flight from Odessa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to South Carolina

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 29, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from Odessa to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,936 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Odessa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the most popular routes from Odessa to South Carolina?

    While some choose either Midland Intl - Charlotte Douglas or Midland Intl - Myrtle Beach Intl, Midland Intl - Savannah/Hilton Head is the most popular route from Odessa to South Carolina.

  • Can I find deals for flights from Odessa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Odessa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to South Carolina.

  • Can I find deals for business class flights from Odessa to South Carolina?

    Yes. Cheapflights offers flight deals from Odessa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Odessa to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Odessa to South Carolina (average of $217). Flying from Odessa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Odessa to South Carolina

Discover the top airline that operate flights from Odessa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$436FlexibilityNo cancel feeOn-time71%

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