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South Carolina

$194+ Cheap flights from Odessa, TX to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/6. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — CHS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Odessa to South Carolina

Keep the following information in mind while searching for Odessa to South Carolina flight deals. Data was last updated June 12, 2025.

Round-trip from

$285
(American Airlines)

One-way from

$194
(American Airlines)
From Odessa to South Carolina
Search Deals
One-way flight from Odessa to South Carolina
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Find flight deals from Odessa to South Carolina

Cheapest flights from Odessa to South Carolina
Explore the most affordable flight options available from Odessa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/62:32 pmMAF - CLT
1 stop4h 53mAmerican Airlines
Tue 8/123:05 pmCLT - MAF
1 stop4h 51mAmerican Airlines
Deal found 6/12$285
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/712:37 pmMAF - CLT
2 stops10h 06mDelta
Mon 8/185:00 pmCLT - MAF
2 stops7h 58mDelta
Deal found 6/10$295
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/168:59 amMAF - MYR
1 stop6h 23mAmerican Airlines
Tue 8/191:12 pmMYR - MAF
2 stops6h 44mAmerican Airlines
Deal found 6/12$301
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1612:31 pmMAF - MYR
2 stops10h 18mDelta
Tue 8/196:00 amMYR - MAF
2 stops6h 51mDelta
Deal found 6/10$306
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/55:40 pmMAF - CLT
1 stop4h 35mSouthwest
Tue 7/84:50 pmCLT - MAF
1 stop7h 05mSouthwest
Deal found 6/11$328
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/189:50 amMAF - SAV
1 stop7h 35mSouthwest
Mon 9/226:40 pmSAV - MAF
1 stop4h 50mSouthwest
Deal found 6/10$329
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2512:34 pmMAF - SAV
2 stops9h 13mDelta
Sun 6/295:23 amSAV - MAF
2 stops7h 31mDelta
Deal found 6/10$437
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/255:00 amMAF - SAV
1 stop7h 27mAmerican Airlines
Sun 6/297:18 amSAV - MAF
1 stop7h 47mAmerican Airlines
Deal found 6/10$463
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/273:30 pmMAF - SAV
1 stop5h 30mUnited Airlines
Tue 7/19:33 amSAV - MAF
2 stops13h 21mUnited Airlines
Deal found 6/11$533
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/285:00 amMAF - CLT
2 stops11h 16mUnited Airlines
Sat 7/125:00 pmCLT - MAF
1 stop7h 12mUnited Airlines
Deal found 6/11$548
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/135:00 amMAF - MYR
2 stops10h 30mUnited Airlines
Sun 8/1710:53 amMYR - MAF
3 stops13h 19mUnited Airlines
Deal found 6/11$2,303

Cheapflights Fare Finder

Customize your flight search to find flights from Odessa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Odessa to South Carolina that are best for you.

Fly from

Odessa

Fly to

South Carolina

Route

Depart

Return

Price

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

Wed 8/6

2:32 pm-8:25 pm

1 stop4h 53m

Charlotte Douglas

Tue 8/12

3:05 pm-6:56 pm

1 stop4h 51m

$285

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

Thu 8/7

12:37 pm-11:43 pm

2 stops10h 06m

Charlotte Douglas

Mon 8/18

5:00 pm-11:58 pm

2 stops7h 58m

$295

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

Sat 8/16

7:36 am-4:22 pm

1 stop7h 46m

Myrtle Beach Intl

Tue 8/19

1:12 pm-6:56 pm

2 stops6h 44m

$301

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

Sat 8/16

12:31 pm-11:49 pm

2 stops10h 18m

Myrtle Beach Intl

Tue 8/19

6:00 am-11:51 am

2 stops6h 51m

$306

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

Sat 7/5

5:40 pm-11:15 pm

1 stop4h 35m

Charlotte Douglas

Tue 7/8

4:50 pm-10:55 pm

1 stop7h 05m

$328

MidlandSavannah

MAF - SAV

MAFSAV

Midland Intl

Thu 9/18

9:50 am-6:25 pm

1 stop7h 35m

Savannah/Hilton Head

Mon 9/22

6:40 pm-10:30 pm

1 stop4h 50m

$329

MidlandSavannah

MAF - SAV

MAFSAV

Midland Intl

Wed 6/25

12:34 pm-10:47 pm

2 stops9h 13m

Savannah/Hilton Head

Sun 6/29

5:23 am-11:54 am

2 stops7h 31m

$437

MidlandSavannah

MAF - SAV

MAFSAV

Midland Intl

Wed 6/25

5:00 am-1:27 pm

1 stop7h 27m

Savannah/Hilton Head

Sun 6/29

7:18 am-2:05 pm

1 stop7h 47m

$463

MidlandSavannah

MAF - SAV

MAFSAV

Midland Intl

Fri 6/27

3:30 pm-10:00 pm

1 stop5h 30m

Savannah/Hilton Head

Tue 7/1

9:33 am-9:54 pm

2 stops13h 21m

$533

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

Sat 6/28

5:00 am-5:16 pm

2 stops11h 16m

Charlotte Douglas

Sat 7/12

5:00 pm-11:12 pm

1 stop7h 12m

$548

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 13 results
1
2

Best time to book a flight from Odessa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to South Carolina

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 12, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from Odessa to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Overall

8.0

Entertainment

7.6

Food

7.1

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Overall

8.0

Entertainment

7.6

Food

7.1

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,950 reviews
Southwest
8.0
Very good
4,287 reviews

Overall

8.0

Entertainment

7.6

Food

7.1

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Overall

8.0

Entertainment

7.6

Food

7.1

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Overall

8.0

Entertainment

7.6

Food

7.1

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Odessa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the most popular routes from Odessa to South Carolina?

    While some choose either Midland Intl - Myrtle Beach Intl or Midland Intl - Savannah/Hilton Head, Midland Intl - Charlotte Douglas is the most popular route from Odessa to South Carolina.

  • Can I find deals for flights from Odessa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Odessa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to South Carolina.

  • Can I find deals for business class flights from Odessa to South Carolina?

    Yes. Cheapflights offers flight deals from Odessa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Odessa to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Odessa to South Carolina (average of $217). Flying from Odessa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Odessa to South Carolina

Discover the top airline that operate flights from Odessa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$374FlexibilityNo cancel feeOn-time71%

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