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South Carolina

$81+ Cheap flights from Nebraska to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
OMA — CHS
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Nebraska to South Carolina

Cheapest flights from Nebraska to South Carolina
Explore the most affordable flight options available from Nebraska to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:37 pmOMA - CLT
1 stop24h 47mMultiple Airlines
Wed 1/711:58 amCLT - OMA
2 stops25h 18mMultiple Airlines
Deal found 12/10$260
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:37 pmOMA - CLT
1 stop19h 50mMultiple Airlines
Tue 1/69:04 pmCLT - OMA
2 stops40h 12mMultiple Airlines
Deal found 12/10$275
This Frontier deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2211:11 amOMA - CLT
1 stop8h 47mFrontier
Tue 12/3012:17 pmCLT - OMA
1 stop8h 30mFrontier
Deal found 12/9$293
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:44 pmOMA - SAV
1 stop5h 24mAmerican Airlines
Thu 1/18:15 pmSAV - OMA
1 stop4h 44mAmerican Airlines
Deal found 12/11$314
This Booking.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1911:24 amOMA - CLT
1 stop7h 45mFrontier
Sun 1/42:22 pmCLT - OMA
1 stop20h 54mFrontier
Deal found 12/8$330
This Delta deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:35 amOMA - CLT
1 stop4h 18mDelta
Wed 1/72:25 pmCLT - OMA
1 stop5h 45mDelta
Deal found 12/8$377
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:32 pmOMA - CLT
1 stop26h 07mMultiple Airlines
Wed 1/711:58 amCLT - OMA
2 stops25h 18mMultiple Airlines
Deal found 12/8$380
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:42 pmOMA - CLT
2 stops34h 50mMultiple Airlines
Thu 1/88:46 pmCLT - OMA
1 stop23h 10mMultiple Airlines
Deal found 12/8$391
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:32 pmOMA - CLT
1 stop26h 07mMultiple Airlines
Thu 1/88:46 pmCLT - OMA
1 stop23h 10mMultiple Airlines
Deal found 12/8$395
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:42 pmOMA - CLT
1 stop18h 37mMultiple Airlines
Wed 1/711:58 amCLT - OMA
2 stops25h 18mMultiple Airlines
Deal found 12/8$398
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:58 pmOMA - CHS
1 stop4h 34mAmerican Airlines
Tue 12/308:08 pmCHS - OMA
1 stop4h 51mAmerican Airlines
Deal found 12/10$408
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:45 amOMA - CHS
1 stop8h 24mUnited Airlines
Mon 12/296:05 amCHS - OMA
1 stop5h 41mUnited Airlines
Deal found 12/9$421

Find flight deals from Nebraska to South Carolina

Keep the following information in mind while searching for Nebraska to South Carolina flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$238
(Delta)

One-way from

$81
(Frontier)

Popular in

December

Cheapest in

September

Average price

$478
Provider with most accurate pricing for Omaha Eppley Airfield-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Omaha Eppley Airfield-Myrtle Beach Intl flights.
Search Deals
From Nebraska to South Carolina
Search Deals
One-way flight from Nebraska to South Carolina
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($9 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Nebraska to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Nebraska to South Carolina that are best for you.

Fly from

Nebraska

Fly to

South Carolina

Route

Depart

Return

Price

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Sat 1/17

12:15 pm-7:25 pm

1 stop6h 10m

Columbia Metropolitan

Sat 1/24

3:09 pm-6:39 pm

1 stop4h 30m

$238

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 1/14

12:15 pm-7:25 pm

1 stop6h 10m

Columbia Metropolitan

Sun 1/25

5:00 pm-10:34 pm

1 stop6h 34m

$259

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 1/14

8:00 am-2:17 pm

1 stop5h 17m

Columbia Metropolitan

Sat 1/24

3:09 pm-6:39 pm

1 stop4h 30m

$259

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 1/14

5:22 am-12:28 pm

1 stop6h 06m

Columbia Metropolitan

Sat 1/24

10:10 am-5:49 pm

2 stops8h 39m

$264

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 1/14

12:14 pm-10:59 pm

2 stops9h 45m

Columbia Metropolitan

Sun 1/25

11:59 am-4:14 pm

1 stop5h 15m

$264

OmahaSavannah

OMA - SAV

OMASAV

Omaha Eppley Airfield

Wed 1/14

10:55 am-4:50 pm

1 stop4h 55m

Savannah/Hilton Head

Sun 1/18

6:05 am-10:05 am

1 stop5h 00m

$308

OmahaSavannah

OMA - SAV

OMASAV

Omaha Eppley Airfield

Tue 1/20

6:06 am-1:17 pm

1 stop6h 11m

Savannah/Hilton Head

Tue 2/10

3:54 pm-11:07 pm

1 stop8h 13m

$308

OmahaCharleston

OMA - CHS

OMACHS

Omaha Eppley Airfield

Thu 1/15

11:26 am-8:02 pm

1 stop7h 36m

Charleston

Tue 1/20

4:41 pm-9:58 pm

1 stop6h 17m

$308

OmahaCharleston

OMA - CHS

OMACHS

Omaha Eppley Airfield

Thu 1/15

6:48 am-2:22 pm

1 stop6h 34m

Charleston

Tue 1/20

6:30 am-10:05 am

1 stop4h 35m

$308

OmahaSavannah

OMA - SAV

OMASAV

Omaha Eppley Airfield

Sat 2/7

5:30 am-1:48 pm

1 stop7h 18m

Savannah/Hilton Head

Sat 2/14

3:00 pm-9:17 pm

1 stop7h 17m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Showing 1-10 of 56 results
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Best time to book a flight from Nebraska to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Nebraska with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Nebraska to South Carolina

What is the cheapest month to book a flight from Nebraska to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Nebraska to South Carolina (average of $142). Flying from Nebraska to South Carolina in May is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NE to SC?

Find hourly flight availability from Nebraska to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

When flying from Nebraska to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 29% versus a flight in the morning.

What is the cheapest day to fly from Nebraska to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Nebraska to South Carolina. Price data was last updated on February 23, 2025.

Travelers seeking maximum savings on their Nebraska to South Carolina flight should consider departing on Thursday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Nebraska to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,095 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Nebraska to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Nebraska to South Carolina?

    For as low as $308, Delta can have you in South Carolina from Nebraska in 4h 55m. There are 1028 mi between Nebraska and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Nebraska to South Carolina one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $163. United Airlines flights start at $168 while deals on Delta start at $173 one-way.

  • Can I find deals for flights from Nebraska to South Carolina that include hotel bookings?

    Yes. In addition to deals on Nebraska to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Nebraska to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Nebraska to South Carolina.

  • Can I find deals for business class flights from Nebraska to South Carolina?

    Yes. Cheapflights offers flight deals from Nebraska to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Nebraska to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Nebraska to South Carolina (average of $142). Flying from Nebraska to South Carolina in May is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Nebraska to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Nebraska to South Carolina

Discover the top 4 airlines that operate flights from Nebraska to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$142Average$389FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$421FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$258Average$414FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$284Average$433FlexibilityNo cancel feeOn-time63%

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