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South Carolina

$90+ Cheap flights from Nebraska to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
OMA — CHS
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
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Cheap flight deals from Nebraska to South Carolina

Cheapest flights from Nebraska to South Carolina
Explore the most affordable flight options available from Nebraska to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:00 amOMA - CLT
1 stop7h 56mDelta
Thu 1/111:30 amCLT - OMA
1 stop6h 32mDelta
Deal found 12/28$377
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:19 amOMA - CLT
1 stop5h 06mDelta
Wed 1/76:00 amCLT - OMA
1 stop6h 36mDelta
Deal found 12/28$441
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:15 amOMA - CLT
1 stop6h 24mUnited Airlines
Thu 1/111:02 amCLT - OMA
2 stops10h 17mUnited Airlines
Deal found 12/28$452
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:19 pmOMA - CLT
1 stop4h 37mDelta
Mon 1/55:00 pmCLT - OMA
1 stop5h 05mDelta
Deal found 12/28$476
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:15 amOMA - CLT
Nonstop2h 42mAmerican Airlines
Sat 1/311:20 amCLT - OMA
Nonstop2h 48mAmerican Airlines
Deal found 12/29$485
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:58 pmOMA - CLT
Nonstop2h 32mAmerican Airlines
Sun 1/410:25 pmCLT - OMA
Nonstop2h 34mAmerican Airlines
Deal found 12/28$491
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:22 pmOMA - CLT
1 stop4h 24mDelta
Wed 1/71:13 pmCLT - OMA
1 stop6h 57mDelta
Deal found 12/28$505
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:10 amOMA - CLT
1 stop8h 29mUnited Airlines
Mon 1/52:54 pmCLT - OMA
2 stops8h 04mUnited Airlines
Deal found 12/28$516
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:04 amOMA - CHS
1 stop16h 22mAmerican Airlines
Fri 1/27:10 pmCHS - OMA
1 stop14h 41mAmerican Airlines
Deal found 12/27$611
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:04 amOMA - SAV
1 stop16h 04mAmerican Airlines
Sun 1/47:35 pmSAV - OMA
1 stop14h 16mAmerican Airlines
Deal found 12/28$712
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:04 amOMA - CHS
1 stop16h 22mAmerican Airlines
Sun 1/47:17 pmCHS - OMA
1 stop14h 34mAmerican Airlines
Deal found 12/28$727
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:04 amOMA - SAV
1 stop8h 45mAmerican Airlines
Sun 1/47:35 pmSAV - OMA
1 stop14h 16mAmerican Airlines
Deal found 12/28$827

Find flight deals from Nebraska to South Carolina

Keep the following information in mind while searching for Nebraska to South Carolina flight deals. Data was last updated December 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$271
(American Airlines)

One-way from

$90
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$478
Provider with most accurate pricing for Omaha Eppley Airfield-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Omaha Eppley Airfield-Myrtle Beach Intl flights.
Search Deals
From Nebraska to South Carolina
Search Deals
One-way flight from Nebraska to South Carolina
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($7 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Nebraska to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Nebraska to South Carolina that are best for you.

Fly from

Nebraska

Fly to

South Carolina

Route

Depart

Return

Price

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Sat 4/4

5:17 pm-11:57 pm

1 stop5h 40m

Columbia Metropolitan

Wed 4/8

8:12 pm-12:22 am

1 stop5h 10m

$271

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 2/18

3:03 pm-9:20 pm

1 stop5h 17m

Columbia Metropolitan

Sat 2/21

6:15 pm-12:15 am

1 stop7h 00m

$271

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 2/18

3:22 pm-11:44 pm

2 stops7h 22m

Columbia Metropolitan

Sat 2/21

3:32 pm-9:59 pm

1 stop7h 27m

$276

LincolnCharleston

LNK - CHS

LNKCHS

Lincoln

Sat 2/28

6:00 am-1:52 pm

1 stop6h 52m

Charleston

Wed 3/4

5:05 pm-9:57 pm

1 stop5h 52m

$279

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 4/8

1:57 pm-9:45 pm

1 stop6h 48m

Columbia Metropolitan

Sat 4/11

4:16 pm-9:56 pm

1 stop6h 40m

$290

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 3/4

2:54 pm-8:27 pm

1 stop4h 33m

Columbia Metropolitan

Sat 3/7

6:40 am-10:33 am

1 stop4h 53m

$291

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Wed 2/11

6:10 am-11:19 am

1 stop4h 09m

Greenville

Wed 2/18

7:29 am-11:46 am

1 stop5h 17m

$293

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Tue 1/13

6:10 am-1:22 pm

1 stop6h 12m

Columbia Metropolitan

Sat 1/24

10:10 am-2:36 pm

1 stop5h 26m

$294

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Fri 1/16

3:07 pm-8:53 pm

1 stop4h 46m

Columbia Metropolitan

Wed 1/21

10:10 am-2:14 pm

1 stop5h 04m

$294

OmahaSavannah

OMA - SAV

OMASAV

Omaha Eppley Airfield

Sat 1/17

9:25 am-7:04 pm

1 stop8h 39m

Savannah/Hilton Head

Tue 1/20

5:30 am-10:05 am

1 stop5h 35m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 50 results
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Best time to book a flight from Nebraska to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Nebraska with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Nebraska to South Carolina

What is the cheapest month to book a flight from Nebraska to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Nebraska to South Carolina (average of $142). Flying from Nebraska to South Carolina in December is currently the most expensive (average of $326). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NE to SC?

Find hourly flight availability from Nebraska to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 30, 2025.

When flying from Nebraska to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 26% versus a flight in the evening.

What is the cheapest day to fly from Nebraska to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Nebraska to South Carolina. Price data was last updated on February 23, 2025.

Travelers seeking maximum savings on their Nebraska to South Carolina flight should consider departing on Thursday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 30, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Nebraska to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,251 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,251 reviews
Southwest
8.0
Very good
4,251 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,014 reviews
Southwest
8.0
Very good
4,251 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,121 reviews
Southwest
8.0
Very good
4,251 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,074 reviews
Southwest
8.0
Very good
4,251 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Nebraska to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Nebraska to South Carolina?

    For as low as $271, American Airlines can have you in South Carolina from Nebraska in 5h 40m. There are 952 mi between Nebraska and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Nebraska to South Carolina one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $142. United Airlines flights start at $154 while deals on Southwest start at $163 one-way.

  • Can I find deals for flights from Nebraska to South Carolina that include hotel bookings?

    Yes. In addition to deals on Nebraska to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Nebraska to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Nebraska to South Carolina.

  • Can I find deals for business class flights from Nebraska to South Carolina?

    Yes. Cheapflights offers flight deals from Nebraska to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Nebraska to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Nebraska to South Carolina (average of $142). Flying from Nebraska to South Carolina in December is currently the most expensive (average of $326). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Nebraska to South Carolina

Discover the top 4 airlines that operate flights from Nebraska to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$142Average$381FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$443FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$258Average$416FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$284Average$435FlexibilityNo cancel feeOn-time63%

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