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South Carolina

$85+ Cheap flights from Nebraska to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
OMA — CHS
Feb 13 — Feb 201
Fri 2/13
Fri 2/20
1 adult, Economy
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Cheap flight deals from Nebraska to South Carolina

Keep the following information in mind while searching for Nebraska to South Carolina flight deals. Data was last updated January 14, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$273
(American Airlines)

One-way from

$85
(Kiwi.com)

Popular in

June

Cheapest in

September

Average price

$396
Provider with most accurate pricing for Omaha Eppley Airfield-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Omaha Eppley Airfield-Myrtle Beach Intl flights.
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From Nebraska to South Carolina
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One-way flight from Nebraska to South Carolina
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Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Nebraska to South Carolina

Cheapest flights from Nebraska to South Carolina
Explore the most affordable flight options available from Nebraska to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 14, 2026.

This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:00 am
OMA
-
HHH
2 stops9h 44m
American Airlines
Sat 2/286:20 pm
HHH
-
OMA
1 stop6h 55m
American Airlines
Deal found 1/13$284
This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:17 pm
OMA
-
CAE
1 stop5h 40m
American Airlines
Tue 3/314:05 pm
CAE
-
OMA
1 stop8h 26m
American Airlines
Deal found 1/12$290
This Delta deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:10 am
OMA
-
CAE
1 stop8h 16m
Delta
Sat 3/285:34 am
CAE
-
OMA
1 stop6h 31m
Delta
Deal found 1/13$291
This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/65:04 pm
OMA
-
CAE
1 stop4h 55m
American Airlines
Mon 2/94:57 pm
CAE
-
OMA
1 stop7h 36m
American Airlines
Deal found 1/12$294
This Delta deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/62:50 pm
OMA
-
CAE
1 stop4h 37m
Delta
Mon 2/95:00 pm
CAE
-
OMA
1 stop6h 34m
Delta
Deal found 1/12$299
This United Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/283:20 pm
OMA
-
CAE
2 stops7h 24m
United Airlines
Tue 3/316:30 am
CAE
-
OMA
1 stop5h 05m
United Airlines
Deal found 1/12$304
This United Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/275:50 am
LNK
-
CHS
1 stop5h 42m
United Airlines
Sat 1/314:01 pm
CHS
-
LNK
1 stop8h 12m
United Airlines
Deal found 1/11$309
This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/276:10 am
OMA
-
CAE
1 stop4h 24m
American Airlines
Sat 1/318:17 am
CAE
-
OMA
1 stop7h 19m
American Airlines
Deal found 1/12$309
This United Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/273:21 pm
OMA
-
CAE
2 stops7h 23m
United Airlines
Sat 1/3110:10 am
CAE
-
OMA
1 stop5h 15m
United Airlines
Deal found 1/12$314
This United Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/277:35 am
LNK
-
SAV
1 stop6h 03m
United Airlines
Sat 1/312:13 pm
SAV
-
LNK
2 stops10h 00m
United Airlines
Deal found 1/12$314
This United Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/103:21 pm
OMA
-
GSP
1 stop4h 26m
United Airlines
Tue 2/176:30 am
GSP
-
OMA
1 stop4h 59m
United Airlines
Deal found 1/11$317
This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/113:57 pm
OMA
-
GSP
1 stop5h 48m
American Airlines
Wed 3/187:14 am
GSP
-
OMA
1 stop7h 11m
American Airlines
Deal found 1/13$319

Cheapflights Fare Finder

 
Customize your flight search to find flights from Nebraska to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
Use the filters below to find and compare flights from Nebraska to South Carolina that are best for you.

Fly from

Nebraska

Fly to

South Carolina

Route

Depart

Return

Price

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Sat 3/28

5:17 pm-11:57 pm

1 stop5h 40m

Columbia Metropolitan

Tue 3/31

4:05 pm-11:31 pm

1 stop8h 26m

$290

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 3/25

7:10 am-4:26 pm

1 stop8h 16m

Columbia Metropolitan

Sat 3/28

5:34 am-11:05 am

1 stop6h 31m

$291

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Fri 2/6

5:04 pm-10:59 pm

1 stop4h 55m

Columbia Metropolitan

Mon 2/9

4:57 pm-11:33 pm

1 stop7h 36m

$294

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Fri 2/6

2:50 pm-8:27 pm

1 stop4h 37m

Columbia Metropolitan

Mon 2/9

5:00 pm-10:34 pm

1 stop6h 34m

$299

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Sat 3/28

3:20 pm-11:44 pm

2 stops7h 24m

Columbia Metropolitan

Tue 3/31

6:30 am-10:35 am

1 stop5h 05m

$304

LincolnCharleston

LNK - CHS

LNKCHS

Lincoln

Tue 1/27

5:50 am-12:32 pm

1 stop5h 42m

Charleston

Sat 1/31

4:01 pm-11:13 pm

1 stop8h 12m

$309

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 1/28

8:00 am-6:55 pm

2 stops9h 55m

Columbia Metropolitan

Sun 2/1

5:07 pm-9:58 pm

1 stop5h 51m

$314

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Tue 1/27

3:21 pm-11:44 pm

2 stops7h 23m

Columbia Metropolitan

Sat 1/31

10:10 am-2:25 pm

1 stop5h 15m

$314

LincolnSavannah

LNK - SAV

LNKSAV

Lincoln

Tue 1/27

7:35 am-2:38 pm

1 stop6h 03m

Savannah/Hilton Head

Sat 1/31

2:13 pm-11:13 pm

2 stops10h 00m

$314

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Tue 2/10

3:21 pm-8:47 pm

1 stop4h 26m

Greenville

Tue 2/17

6:30 am-10:29 am

1 stop4h 59m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/12

Showing 1-10 of 55 results
1
2
3
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6

Best time to book a flight from Nebraska to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Nebraska with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Nebraska to South Carolina

What is the cheapest month to book a flight from Nebraska to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Nebraska to South Carolina (average of $142). Flying from Nebraska to South Carolina in December is currently the most expensive (average of $310). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NE to SC?

Find hourly flight availability from Nebraska to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 14, 2026.

When flying from Nebraska to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 26% versus a flight in the evening.

What is the cheapest day to fly from Nebraska to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Nebraska to South Carolina. Price data was last updated on February 23, 2025.

Travelers seeking maximum savings on their Nebraska to South Carolina flight should consider departing on Thursday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 14, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Nebraska to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,257 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,257 reviews
Southwest
8.0
Very good
4,257 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,040 reviews
Southwest
8.0
Very good
4,257 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,156 reviews
Southwest
8.0
Very good
4,257 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,118 reviews
Southwest
8.0
Very good
4,257 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Nebraska to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Nebraska to South Carolina?

    For as low as $290, American Airlines can have you in South Carolina from Nebraska in 5h 40m. There are 952 mi between Nebraska and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Nebraska to South Carolina one-way?

    To fly one-way, consider booking your trip with Aeromexico, which is currently one of the cheapest options available, starting at $154. American Airlines flights start at $164 while deals on United Airlines start at $166 one-way.

  • Can I find deals for flights from Nebraska to South Carolina that include hotel bookings?

    Yes. In addition to deals on Nebraska to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Nebraska to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Nebraska to South Carolina.

  • Can I find deals for business class flights from Nebraska to South Carolina?

    Yes. Cheapflights offers flight deals from Nebraska to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Nebraska to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Nebraska to South Carolina (average of $142). Flying from Nebraska to South Carolina in December is currently the most expensive (average of $310). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Nebraska to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Nebraska to South Carolina

Discover the top 4 airlines that operate flights from Nebraska to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$142Average$388FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$449FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$258Average$409FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$284Average$436FlexibilityNo cancel feeOn-time63%

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