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South Carolina

$78+ Cheap flights from Nebraska to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
OMA — CHS
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Cheap flight deals from Nebraska to South Carolina

Keep the following information in mind while searching for Nebraska to South Carolina flight deals. Data was last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$223
(Kiwi.com)

One-way from

$78
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$296
Provider with most accurate pricing for Omaha Eppley Airfield-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Omaha Eppley Airfield-Myrtle Beach Intl flights.
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From Nebraska to South Carolina
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One-way flight from Nebraska to South Carolina
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Highest demand for flights based on searches. 4% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Nebraska to South Carolina

Cheapest flights from Nebraska to South Carolina
Explore the most affordable flight options available from Nebraska to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:24 pmOMA - CLT
1 stop25h 25mMultiple Airlines
Sun 12/710:33 pmCLT - OMA
1 stop21h 11mMultiple Airlines
Deal found 11/18$223
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:34 pmOMA - CLT
1 stop11h 23mMultiple Airlines
Sun 12/75:44 pmCLT - OMA
2 stops22h 44mMultiple Airlines
Deal found 11/19$286
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:07 amOMA - CAE
1 stop4h 05mDelta
Fri 12/265:36 pmCAE - OMA
1 stop4h 35mDelta
Deal found 11/19$299
This United Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amLNK - SAV
2 stops7h 39mUnited Airlines
Mon 12/84:49 pmSAV - LNK
1 stop5h 55mUnited Airlines
Deal found 11/19$314
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:25 pmOMA - GSP
1 stop4h 24mUnited Airlines
Wed 12/105:00 pmGSP - OMA
1 stop6h 28mUnited Airlines
Deal found 11/18$317
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:34 pmOMA - CLT
1 stop13h 45mAmerican Airlines
Wed 12/3111:20 amCLT - OMA
Nonstop2h 48mAmerican Airlines
Deal found 11/17$317
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/252:03 pmOMA - CLT
Nonstop2h 32mAmerican Airlines
Wed 12/312:24 pmCLT - OMA
Nonstop2h 50mAmerican Airlines
Deal found 11/18$321
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:45 pmLNK - CLT
1 stop8h 11mUnited Airlines
Sun 12/146:30 amCLT - LNK
1 stop5h 15mUnited Airlines
Deal found 11/20$325
This Southwest deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:25 amOMA - GSP
2 stops8h 40mSouthwest
Wed 12/107:40 amGSP - OMA
2 stops10h 10mSouthwest
Deal found 11/18$327
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:06 amOMA - CLT
1 stop12h 29mAmerican Airlines
Fri 12/2610:25 pmCLT - OMA
Nonstop2h 34mAmerican Airlines
Deal found 11/18$327
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/223:11 pmLNK - CLT
1 stop5h 09mUnited Airlines
Mon 12/296:20 amCLT - LNK
1 stop5h 40mUnited Airlines
Deal found 11/20$329
This Southwest deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/101:25 pmOMA - SAV
1 stop5h 10mSouthwest
Wed 12/171:20 pmSAV - OMA
1 stop4h 30mSouthwest
Deal found 11/18$335

Cheapflights Fare Finder

 
Customize your flight search to find flights from Nebraska to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Nebraska to South Carolina that are best for you.

Fly from

Nebraska

Fly to

South Carolina

Route

Depart

Return

Price

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 1/21

6:48 am-3:47 pm

1 stop7h 59m

Columbia Metropolitan

Sat 1/24

10:15 am-3:14 pm

1 stop5h 59m

$259

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Sat 1/31

5:30 am-11:08 am

1 stop4h 38m

Greenville

Wed 2/4

6:50 am-10:05 am

1 stop4h 15m

$289

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Fri 12/19

5:07 am-10:12 am

1 stop4h 05m

Columbia Metropolitan

Fri 12/26

5:36 pm-9:11 pm

1 stop4h 35m

$299

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Tue 2/17

6:55 am-3:42 pm

1 stop7h 47m

Columbia Metropolitan

Sat 2/21

8:45 am-3:11 pm

1 stop7h 26m

$299

OmahaSavannah

OMA - SAV

OMASAV

Omaha Eppley Airfield

Sat 2/7

3:26 pm-9:00 pm

1 stop4h 34m

Savannah/Hilton Head

Sat 2/14

6:00 am-12:38 pm

1 stop7h 38m

$305

OmahaCharleston

OMA - CHS

OMACHS

Omaha Eppley Airfield

Thu 2/5

5:04 pm-11:07 pm

1 stop5h 03m

Charleston

Mon 2/9

5:41 pm-10:14 pm

1 stop5h 33m

$305

OmahaCharleston

OMA - CHS

OMACHS

Omaha Eppley Airfield

Tue 2/17

7:06 am-2:06 pm

1 stop6h 00m

Charleston

Sat 2/21

7:00 am-3:34 pm

1 stop9h 34m

$305

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Thu 2/12

6:55 am-3:42 pm

1 stop7h 47m

Columbia Metropolitan

Sun 2/15

6:40 am-10:35 am

1 stop4h 55m

$309

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Fri 2/13

2:50 pm-9:48 pm

1 stop5h 58m

Columbia Metropolitan

Sun 2/15

6:40 am-10:35 am

1 stop4h 55m

$309

OmahaSavannah

OMA - SAV

OMASAV

Omaha Eppley Airfield

Wed 2/18

12:12 pm-10:58 pm

2 stops9h 46m

Savannah/Hilton Head

Sat 2/21

8:09 pm-12:15 am

1 stop5h 06m

$310

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 59 results
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Best time to book a flight from Nebraska to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Nebraska with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Nebraska to South Carolina

What is the cheapest month to book a flight from Nebraska to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Nebraska to South Carolina (average of $142). Flying from Nebraska to South Carolina in December is currently the most expensive (average of $315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NE to SC?

Find hourly flight availability from Nebraska to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

When flying from Nebraska to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 26% versus a flight in the morning.

What is the cheapest day to fly from Nebraska to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Nebraska to South Carolina. Price data was last updated on February 23, 2025.

Travelers seeking maximum savings on their Nebraska to South Carolina flight should consider departing on Thursday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 20, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Nebraska to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,251 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,002 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,028 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,047 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Nebraska to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Nebraska to South Carolina?

    For as low as $305, Delta can have you in South Carolina from Nebraska in 4h 34m. There are 1028 mi between Nebraska and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Nebraska to South Carolina one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $78. Allegiant Air flights start at $163 while deals on Southwest start at $214 one-way.

  • Can I find deals for flights from Nebraska to South Carolina that include hotel bookings?

    Yes. In addition to deals on Nebraska to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Nebraska to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Nebraska to South Carolina.

  • Can I find deals for business class flights from Nebraska to South Carolina?

    Yes. Cheapflights offers flight deals from Nebraska to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Nebraska to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Nebraska to South Carolina (average of $142). Flying from Nebraska to South Carolina in December is currently the most expensive (average of $315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Nebraska to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Nebraska to South Carolina

Discover the top 4 airlines that operate flights from Nebraska to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$142Average$401FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$437FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$258Average$414FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$284Average$395FlexibilityNo cancel feeOn-time63%

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