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South Carolina

$70+ Cheap flights from Nebraska to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
OMA — CHS
Mar 27 — Apr 31
Fri 3/27
Fri 4/3
1 adult, Economy
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Cheap flight deals from Nebraska to South Carolina

Cheapest flights from Nebraska to South Carolina
Explore the most affordable flight options available from Nebraska to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 25, 2026.

This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/211:01 pm
LNK
-
CLT
1 stop8h 58m
United Airlines
Tue 4/286:15 am
CLT
-
LNK
1 stop5h 23m
United Airlines
Deal found 2/21$251
This Southwest deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:35 pm
OMA
-
CLT
1 stop4h 20m
Southwest
Wed 4/226:20 pm
CLT
-
OMA
1 stop5h 00m
Southwest
Deal found 2/24$268
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:04 am
OMA
-
HHH
1 stop7h 16m
Delta
Thu 4/234:00 pm
HHH
-
OMA
1 stop8h 20m
Delta
Deal found 2/23$279
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/412:55 pm
OMA
-
CLT
1 stop8h 55m
Southwest
Tue 4/76:20 pm
CLT
-
OMA
1 stop5h 00m
Southwest
Deal found 2/22$282
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:37 am
OMA
-
GSP
1 stop7h 08m
Delta
Wed 4/86:21 pm
GSP
-
OMA
1 stop6h 10m
Delta
Deal found 2/23$285
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
OMA
-
CAE
1 stop6h 41m
United Airlines
Tue 5/125:35 pm
CAE
-
OMA
1 stop4h 58m
United Airlines
Deal found 2/24$290
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:55 am
OMA
-
GSP
2 stops9h 45m
American Airlines
Wed 4/158:16 pm
GSP
-
OMA
1 stop4h 43m
American Airlines
Deal found 2/23$290
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:01 pm
OMA
-
CHS
1 stop13h 47m
Multiple Airlines
Sat 5/166:00 am
CHS
-
OMA
2 stops39h 14m
Multiple Airlines
Deal found 2/24$291
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/213:40 pm
OMA
-
CLT
1 stop4h 55m
Southwest
Sat 3/286:05 am
CLT
-
OMA
2 stops10h 00m
Southwest
Deal found 2/21$293
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:19 am
OMA
-
HHH
1 stop7h 03m
American Airlines
Sat 3/286:15 pm
HHH
-
OMA
1 stop7h 00m
American Airlines
Deal found 2/24$294
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:50 pm
OMA
-
MYR
1 stop6h 34m
American Airlines
Tue 4/214:52 pm
MYR
-
OMA
1 stop7h 40m
American Airlines
Deal found 2/23$299
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:48 pm
OMA
-
CHS
1 stop7h 20m
Delta
Tue 5/511:26 am
CHS
-
OMA
1 stop6h 34m
Delta
Deal found 2/24$299

Find flight deals from Nebraska to South Carolina

Keep the following information in mind while searching for Nebraska to South Carolina flight deals. Data was last updated February 25, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$251
(United Airlines)

One-way from

$70
(Kiwi.com)

Popular in

February

Cheapest in

September

Average price

$505
Provider with most accurate pricing for Omaha Eppley Airfield-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Omaha Eppley Airfield-Myrtle Beach Intl flights.
Search Deals
From Nebraska to South Carolina
Search Deals
One-way flight from Nebraska to South Carolina
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Nebraska to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 25, 2026.
Use the filters below to find and compare flights from Nebraska to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LincolnCharlotte

LNK - CLT

LNKCLT

Lincoln

Tue 4/21

1:01 pm-10:59 pm

1 stop8h 58m

Charlotte Douglas

Tue 4/28

6:15 am-10:38 am

1 stop5h 23m

$251

OmahaCharlotte

OMA - CLT

OMACLT

Omaha Eppley Airfield

Wed 4/15

3:35 pm-8:55 pm

1 stop4h 20m

Charlotte Douglas

Wed 4/22

6:20 pm-10:20 pm

1 stop5h 00m

$268

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Wed 4/8

12:45 pm-9:34 pm

1 stop7h 49m

Greenville

Wed 4/15

10:00 am-3:13 pm

1 stop6h 13m

$285

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Fri 5/8

6:00 am-1:41 pm

1 stop6h 41m

Columbia Metropolitan

Tue 5/12

5:35 pm-9:33 pm

1 stop4h 58m

$290

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Wed 6/3

12:35 pm-10:47 pm

1 stop9h 12m

Columbia Metropolitan

Wed 6/10

5:40 am-9:58 am

1 stop5h 18m

$301

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Fri 3/20

3:10 pm-9:20 pm

1 stop5h 10m

Columbia Metropolitan

Tue 3/24

5:10 pm-11:31 pm

1 stop7h 21m

$306

LincolnCharleston

LNK - CHS

LNKCHS

Lincoln

Wed 5/6

3:03 pm-11:59 pm

2 stops7h 56m

Charleston

Wed 5/13

1:19 pm-7:45 pm

1 stop7h 26m

$310

OmahaColumbia

OMA - CAE

OMACAE

Omaha Eppley Airfield

Tue 3/17

12:45 pm-9:24 pm

1 stop7h 39m

Columbia Metropolitan

Tue 3/24

6:50 am-10:27 am

1 stop4h 37m

$311

LincolnCharleston

LNK - CHS

LNKCHS

Lincoln

Fri 5/8

6:03 am-12:17 pm

1 stop5h 14m

Charleston

Tue 5/12

1:19 pm-7:45 pm

1 stop7h 26m

$316

OmahaSavannah

OMA - SAV

OMASAV

Omaha Eppley Airfield

Sat 4/18

4:00 pm-11:59 pm

1 stop6h 59m

Savannah/Hilton Head

Tue 4/21

6:50 am-10:43 am

1 stop4h 53m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/23

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
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6

Best time to book a flight from Nebraska to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Nebraska with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Nebraska to South Carolina

What is the cheapest month to book a flight from Nebraska to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Nebraska to South Carolina (average of $142). Flying from Nebraska to South Carolina in December is currently the most expensive (average of $310). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NE to SC?

Find hourly flight availability from Nebraska to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 25, 2026.

When flying from Nebraska to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 26% versus a flight in the evening.

What is the cheapest day to fly from Nebraska to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Nebraska to South Carolina. Price data was last updated on February 23, 2025.

Travelers seeking maximum savings on their Nebraska to South Carolina flight should consider departing on Thursday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 25, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Nebraska to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,300 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,300 reviews
Southwest
8.0
Very good
4,300 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,237 reviews
Southwest
8.0
Very good
4,300 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,345 reviews
Southwest
8.0
Very good
4,300 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,345 reviews
Southwest
8.0
Very good
4,300 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Nebraska to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Nebraska to South Carolina?

    For as low as $268, United Airlines can have you in South Carolina from Nebraska in 4h 20m. There are 911 mi between Nebraska and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Nebraska to South Carolina one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $118. United Airlines flights start at $154 while deals on Delta start at $163 one-way.

  • Can I find deals for flights from Nebraska to South Carolina that include hotel bookings?

    Yes. In addition to deals on Nebraska to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Nebraska to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Nebraska to South Carolina.

  • Can I find deals for business class flights from Nebraska to South Carolina?

    Yes. Cheapflights offers flight deals from Nebraska to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Nebraska to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Nebraska to South Carolina (average of $142). Flying from Nebraska to South Carolina in December is currently the most expensive (average of $310). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Nebraska to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Nebraska to South Carolina

Discover the top 4 airlines that operate flights from Nebraska to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 25, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$142Average$387FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$473FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$284Average$409FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$333Average$489FlexibilityNo cancel feeOn-time69%

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