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South Carolina

$197+ Cheap flights from Mexico City Federal District to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — CHS
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Mexico City Federal District to South Carolina

Cheapest flights from Mexico City Federal District to South Carolina
Explore the most affordable flight options available from Mexico City Federal District to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:45 amMEX - GSP
1 stop10h 18mUnited Airlines
Tue 1/276:35 amGSP - MEX
2 stops13h 20mUnited Airlines
Deal found 12/17$436
This United Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:25 pmMEX - CLT
2 stops21h 06mUnited Airlines
Tue 1/132:54 pmCLT - MEX
2 stops10h 16mUnited Airlines
Deal found 12/18$477
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:45 pmMEX - CLT
1 stop28h 58mMultiple Airlines
Tue 12/307:46 pmCLT - MEX
1 stop23h 59mMultiple Airlines
Deal found 12/16$480
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/211:50 pmMEX - CLT
1 stop17h 10mMultiple Airlines
Mon 3/210:42 pmCLT - MEX
2 stops25h 58mMultiple Airlines
Deal found 12/16$505
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:05 amMEX - GSP
1 stop10h 52mUnited Airlines
Wed 1/74:50 pmGSP - MEX
1 stop8h 20mUnited Airlines
Deal found 12/16$515
This Air Canada deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:05 amMEX - CLT
1 stop18h 52mAir Canada
Thu 1/85:05 pmCLT - MEX
1 stop8h 45mAir Canada
Deal found 12/17$520
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:45 pmMEX - GSP
1 stop22h 18mUnited Airlines
Sat 1/36:45 amGSP - MEX
1 stop13h 10mUnited Airlines
Deal found 12/17$556
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:05 pmMEX - CLT
2 stops40h 37mMultiple Airlines
Thu 1/1511:21 amCLT - MEX
1 stop11h 39mMultiple Airlines
Deal found 12/16$558
This Air Canada deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/211:05 amMEX - CLT
1 stop14h 12mAir Canada
Thu 1/17:50 amCLT - MEX
1 stop18h 00mAir Canada
Deal found 12/16$564
This Priceline deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/211:05 amMEX - CLT
1 stop18h 52mMultiple Airlines
Fri 1/23:07 pmCLT - MEX
1 stop7h 53mMultiple Airlines
Deal found 12/16$566
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:45 amMEX - CLT
2 stops14h 35mUnited Airlines
Fri 1/165:35 pmCLT - MEX
2 stops17h 30mUnited Airlines
Deal found 12/17$576
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:40 amMEX - GSP
2 stops13h 52mDelta
Mon 1/268:22 amGSP - MEX
2 stops11h 33mDelta
Deal found 12/17$577

Find flight deals from Mexico City Federal District to South Carolina

Keep the following information in mind while searching for Mexico City Federal District to South Carolina flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$412
(Kiwi.com)

One-way from

$197
(Kiwi.com)

Popular in

September

Cheapest in

April

Average price

$591
Provider with most accurate pricing for Mexico City Benito Juarez-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Myrtle Beach Intl flights.
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From Mexico City Federal District to South Carolina
Search Deals
One-way flight from Mexico City Federal District to South Carolina
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to South Carolina that are best for you.

Fly from

Mexico City Federal District

Fly to

South Carolina

Route

Depart

Return

Price

Mexico CityCharleston

MEX - CHS

MEXCHS

Mexico City Benito Juarez

Thu 1/15

7:20 pm-5:36 pm

2 stops45h 16m

Charleston

Thu 1/22

3:01 pm-7:45 pm

1 stop29h 44m

$412

Mexico CityGreenville

MEX - GSP

MEXGSP

Mexico City Benito Juarez

Sat 1/31

3:20 pm-2:19 pm

2 stops21h 59m

Greenville

Sat 2/7

6:49 am-2:20 pm

1 stop8h 31m

$477

Mexico CityCharlotte

MEX - CLT

MEXCLT

Mexico City Benito Juarez

Thu 1/8

11:10 am-9:02 am

1 stop20h 52m

Charlotte Douglas

Thu 1/22

11:18 am-10:00 pm

1 stop11h 42m

$477

Mexico CityGreenville

MEX - GSP

MEXGSP

Mexico City Benito Juarez

Fri 1/23

5:45 am-7:29 pm

2 stops12h 44m

Greenville

Fri 1/30

6:35 am-4:45 pm

2 stops11h 10m

$478

Mexico CityCharlotte

MEX - CLT

MEXCLT

Mexico City Benito Juarez

Sat 1/10

10:05 am-10:38 am

1 stop23h 33m

Charlotte Douglas

Wed 1/14

5:04 pm-7:45 pm

1 stop27h 41m

$483

Mexico CityGreenville

MEX - GSP

MEXGSP

Mexico City Benito Juarez

Mon 2/16

5:45 am-9:59 pm

1 stop15h 14m

Greenville

Fri 2/20

10:40 am-10:05 am

2 stops24h 25m

$498

Mexico CityCharlotte

MEX - CLT

MEXCLT

Mexico City Benito Juarez

Sat 1/10

10:05 am-10:45 am

1 stop23h 40m

Charlotte Douglas

Wed 1/14

6:10 am-12:10 am

2 stops19h 00m

$501

Mexico CityCharleston

MEX - CHS

MEXCHS

Mexico City Benito Juarez

Thu 1/15

6:40 am-8:55 pm

2 stops13h 15m

Charleston

Thu 1/22

10:31 am-6:55 pm

2 stops9h 24m

$504

Mexico CityCharleston

MEX - CHS

MEXCHS

Mexico City Benito Juarez

Thu 1/15

7:50 am-8:02 pm

2 stops11h 12m

Charleston

Thu 1/22

1:13 pm-12:10 am

2 stops11h 57m

$505

Mexico CityCharlotte

MEX - CLT

MEXCLT

Mexico City Benito Juarez

Wed 2/18

1:05 am-4:17 pm

1 stop14h 12m

Charlotte Douglas

Tue 2/24

5:05 pm-12:30 pm

1 stop20h 25m

$522

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 37 results
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Best time to book a flight from Mexico City Federal District to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to South Carolina

What is the cheapest month to book a flight from Mexico City Federal District to South Carolina?

Currently, July is the cheapest month in which you can book a flight from Mexico City Federal District to South Carolina (average of $194). Flying from Mexico City Federal District to South Carolina in February is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DF to SC?

Find hourly flight availability from Mexico City Federal District to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from Mexico City Federal District to South Carolina in the evening. By choosing this option you can save up to 51% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Mexico City Federal District to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Mexico City Federal District to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mexico City Federal District to South Carolina flight should consider departing on Friday afternoons when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from Mexico City Federal District to South Carolina, such as Delta, United Airlines, and American Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,091 reviews
Delta
7.9
Good
8,005 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mexico City Federal District to South Carolina?

    Departing from Mexico City Federal District to South Carolina will take you 13h 15m. Airlines will cover a distance of 1497 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Mexico City Federal District to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to South Carolina.

  • Can I find deals for business class flights from Mexico City Federal District to South Carolina?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to South Carolina?

    Currently, July is the cheapest month in which you can book a flight from Mexico City Federal District to South Carolina (average of $194). Flying from Mexico City Federal District to South Carolina in February is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mexico City Federal District to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Mexico City Federal District to South Carolina

Discover the top 3 airlines that operate flights from Mexico City Federal District to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$441Average$615FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$443Average$708FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$569Average$577FlexibilityNo cancel feeOn-time71%

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