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South Carolina

$129+ Cheap flights from Melbourne, FL (MLB) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — CHS
Jun 1 — Jun 81
Mon 6/1
Mon 6/8
1 adult, Economy
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Cheap flight deals from Melbourne to South Carolina

Cheapest flights from Melbourne to South Carolina
Explore the most affordable flight options available from Melbourne to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 2, 2026.

This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:18 pm
MLB
-
GSP
1 stop4h 25m
Delta
Tue 6/23:00 pm
GSP
-
MLB
1 stop3h 20m
Delta
Deal found 4/28$273
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:34 am
MLB
-
CHS
2 stops23h 11m
Multiple Airlines
Thu 6/46:14 pm
CHS
-
MLB
1 stop19h 40m
Multiple Airlines
Deal found 4/30$308
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:37 am
MLB
-
GSP
1 stop3h 41m
Delta
Sun 7/56:45 am
GSP
-
MLB
1 stop3h 43m
Delta
Deal found 4/30$330
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/239:31 am
MLB
-
CHS
1 stop10h 00m
Multiple Airlines
Sun 7/269:00 pm
CHS
-
MLB
1 stop17h 09m
Multiple Airlines
Deal found 4/28$339
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:52 am
MLB
-
MYR
1 stop4h 06m
American Airlines
Wed 6/36:50 am
MYR
-
MLB
1 stop4h 21m
American Airlines
Deal found 4/27$347
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:07 pm
MLB
-
GSP
1 stop4h 45m
American Airlines
Tue 6/21:00 pm
GSP
-
MLB
2 stops10h 52m
American Airlines
Deal found 4/28$348
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:07 pm
MLB
-
CLT
Nonstop1h 58m
American Airlines
Sat 6/64:36 pm
CLT
-
MLB
Nonstop2h 01m
American Airlines
Deal found 4/30$351
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/272:49 pm
MLB
-
SAV
1 stop6h 18m
Delta
Tue 6/305:39 am
SAV
-
MLB
1 stop4h 49m
Delta
Deal found 5/1$357
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/42:49 pm
MLB
-
GSP
1 stop4h 27m
Delta
Wed 7/85:44 am
GSP
-
MLB
1 stop4h 42m
Delta
Deal found 4/30$357
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:46 am
MLB
-
GSP
1 stop4h 53m
Delta
Sun 6/77:51 pm
GSP
-
MLB
1 stop4h 00m
Delta
Deal found 4/30$361
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:18 pm
MLB
-
CHS
1 stop3h 38m
Delta
Tue 5/265:15 am
CHS
-
MLB
1 stop5h 10m
Delta
Deal found 5/1$362
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:06 am
MLB
-
CHS
2 stops23h 39m
Multiple Airlines
Sun 5/107:25 am
CHS
-
MLB
1 stop28h 45m
Multiple Airlines
Deal found 4/27$364

Find flight deals from Melbourne to South Carolina

Keep the following information in mind while searching for Melbourne to South Carolina flight deals. Data was last updated May 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$273
(Delta)

One-way from

$129
(Delta)

Popular in

February

Cheapest in

July

Average price

$151
Provider with most accurate pricing for Orlando (ORL)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Orlando (ORL)-Myrtle Beach Intl flights.
Search Deals
From Melbourne to South Carolina
Search Deals
One-way flight from Melbourne to South Carolina
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Melbourne to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 2, 2026.
Use the filters below to find and compare flights from Melbourne to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Tue 5/26

7:18 pm-11:43 pm

1 stop4h 25m

Greenville

Tue 6/2

3:00 pm-6:20 pm

1 stop3h 20m

$273

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Wed 7/1

5:37 am-9:18 am

1 stop3h 41m

Greenville

Sun 7/5

6:45 am-10:28 am

1 stop3h 43m

$330

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Thu 7/23

9:31 am-7:31 pm

1 stop10h 00m

Charleston

Sun 7/26

9:00 pm-2:09 pm

1 stop17h 09m

$339

MelbourneMyrtle Beach

MLB - MYR

MLBMYR

Melbourne

Wed 5/27

11:52 am-3:58 pm

1 stop4h 06m

Myrtle Beach Intl

Wed 6/3

6:50 am-11:11 am

1 stop4h 21m

$347

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Tue 5/26

7:07 pm-11:52 pm

1 stop4h 45m

Greenville

Tue 6/2

1:00 pm-11:52 pm

2 stops10h 52m

$348

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Tue 6/2

7:07 pm-9:05 pm

Nonstop1h 58m

Charlotte Douglas

Sat 6/6

4:36 pm-6:37 pm

Nonstop2h 01m

$351

MelbourneSavannah

MLB - SAV

MLBSAV

Melbourne

Sat 6/27

2:49 pm-9:07 pm

1 stop6h 18m

Savannah/Hilton Head

Tue 6/30

5:39 am-10:28 am

1 stop4h 49m

$357

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Sat 7/4

2:49 pm-7:16 pm

1 stop4h 27m

Greenville

Wed 7/8

5:44 am-10:26 am

1 stop4h 42m

$357

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Wed 9/23

3:20 pm-9:25 pm

1 stop6h 05m

Greenville

Thu 9/24

6:45 am-10:34 am

1 stop3h 49m

$357

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Wed 5/13

7:18 pm-10:56 pm

1 stop3h 38m

Charleston

Tue 5/26

5:15 am-10:25 am

1 stop5h 10m

$362

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Melbourne to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Melbourne to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Melbourne to South Carolina?

    Located just 2.7 mi from the city center, Melbourne (MLB) is the airport most travelers will use when flying to South Carolina from Melbourne.

  • How long is the flight from Melbourne, Florida to South Carolina?

    A quick flight from Melbourne, Florida to South Carolina can take about 4h 06m. Delta provides one of the quickest options available for as low as $347. There are 399 mi between Melbourne, Florida and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Melbourne, Florida to South Carolina?

    While some choose either Melbourne - Charlotte Douglas or Melbourne - Greenville, Melbourne - Charleston is the most popular route from Melbourne, Florida to South Carolina.

  • Can I find deals for flights from Melbourne to South Carolina that include hotel bookings?

    Yes. In addition to deals on Melbourne to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to South Carolina.

  • Can I find deals for business class flights from Melbourne to South Carolina?

    Yes. Cheapflights offers flight deals from Melbourne to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Melbourne to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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