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South Carolina

$152+ Cheap flights from Melbourne, FL (MLB) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — CHS
Aug 28 — Sep 41
Fri 8/28
Fri 9/4
1 adult, Economy
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Cheap flight deals from Melbourne to South Carolina

Cheapest flights from Melbourne to South Carolina
Explore the most affordable flight options available from Melbourne to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.

This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:33 pm
MLB
-
CLT
Nonstop1h 56m
American Airlines
Sat 9/128:34 pm
CLT
-
MLB
Nonstop1h 43m
American Airlines
Deal found 7/26$361
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:53 pm
MLB
-
SAV
1 stop6h 17m
American Airlines
Sat 8/298:00 am
SAV
-
MLB
1 stop4h 23m
American Airlines
Deal found 7/25$367
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am
MLB
-
GSP
1 stop5h 08m
Delta
Sat 9/266:00 am
GSP
-
MLB
1 stop4h 24m
Delta
Deal found 7/26$367
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:39 pm
MLB
-
CHS
1 stop4h 12m
American Airlines
Sat 12/55:10 am
CHS
-
MLB
1 stop6h 23m
American Airlines
Deal found 7/25$367
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:48 pm
MLB
-
CAE
1 stop5h 05m
Delta
Sun 11/225:35 am
CAE
-
MLB
1 stop4h 51m
Delta
Deal found 7/26$377
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:25 am
MLB
-
MYR
1 stop3h 55m
American Airlines
Mon 9/215:45 pm
MYR
-
MLB
1 stop4h 32m
American Airlines
Deal found 7/24$377
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:55 pm
MLB
-
GSP
1 stop4h 14m
Delta
Sat 8/292:00 pm
GSP
-
MLB
1 stop4h 00m
Delta
Deal found 7/28$377
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:25 am
MLB
-
CHS
1 stop6h 51m
American Airlines
Sat 8/298:12 am
CHS
-
MLB
1 stop4h 11m
American Airlines
Deal found 7/25$377
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:25 am
MLB
-
MYR
1 stop3h 55m
American Airlines
Fri 9/185:45 pm
MYR
-
MLB
1 stop4h 32m
American Airlines
Deal found 7/28$378
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:00 pm
MLB
-
CLT
1 stop3h 48m
Delta
Sat 9/126:00 am
CLT
-
MLB
1 stop5h 33m
Delta
Deal found 7/28$381
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:11 am
MLB
-
CAE
1 stop6h 09m
Delta
Mon 8/311:59 pm
CAE
-
MLB
1 stop4h 01m
Delta
Deal found 7/27$387
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:53 pm
MLB
-
MYR
1 stop5h 58m
American Airlines
Fri 8/285:15 pm
MYR
-
MLB
1 stop5h 08m
American Airlines
Deal found 7/27$387

Find flight deals from Melbourne to South Carolina

Keep the following information in mind while searching for Melbourne to South Carolina flight deals. Data was last updated July 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$361
(American Airlines)

One-way from

$152
(Kiwi.com)

Popular in

December

Cheapest in

June

Average price

$191
Provider with most accurate pricing for Orlando (ORL)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Orlando (ORL)-Myrtle Beach Intl flights.
Search Deals
From Melbourne to South Carolina
Search Deals
One-way flight from Melbourne to South Carolina
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Melbourne to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Melbourne to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Tue 9/8

6:25 am-8:18 am

Nonstop1h 53m

Charlotte Douglas

Sat 9/12

10:40 am-12:28 pm

Nonstop1h 48m

$361
Quickest round-trip

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Sun 9/6

5:33 pm-7:29 pm

Nonstop1h 56m

Charlotte Douglas

Sat 9/12

8:34 pm-10:17 pm

Nonstop1h 43m

$361

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Wed 9/23

6:00 am-11:08 am

1 stop5h 08m

Greenville

Sat 9/26

6:00 am-10:24 am

1 stop4h 24m

$367

MelbourneSavannah

MLB - SAV

MLBSAV

Melbourne

Wed 8/26

12:53 pm-7:10 pm

1 stop6h 17m

Savannah/Hilton Head

Sat 8/29

8:00 am-12:23 pm

1 stop4h 23m

$367

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Tue 12/1

5:39 pm-9:51 pm

1 stop4h 12m

Charleston

Sat 12/5

5:10 am-11:33 am

1 stop6h 23m

$367

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

Fri 11/20

6:48 pm-11:53 pm

1 stop5h 05m

Columbia Metropolitan

Sun 11/22

5:35 am-10:26 am

1 stop4h 51m

$377

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

Sat 11/21

2:26 pm-8:10 pm

1 stop5h 44m

Columbia Metropolitan

Sun 11/22

5:35 am-10:26 am

1 stop4h 51m

$377

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Thu 8/27

2:55 pm-7:09 pm

1 stop4h 14m

Greenville

Sat 8/29

2:00 pm-6:00 pm

1 stop4h 00m

$377

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Thu 8/27

6:25 am-11:22 am

1 stop4h 57m

Greenville

Sat 8/29

5:19 pm-10:23 pm

1 stop5h 04m

$377

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Fri 9/25

6:40 pm-11:59 pm

1 stop5h 19m

Charleston

Mon 9/28

5:25 am-10:24 am

1 stop4h 59m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 59 resultsSorted by cheapest first
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Best time to book a flight from Melbourne to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Melbourne to South Carolina

No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Melbourne to South Carolina?

    Located just 2.7 mi from the city center, Melbourne (MLB) is the airport most travelers will use when flying to South Carolina from Melbourne.

  • How long is the flight from Melbourne, Florida to South Carolina?

    A quick flight from Melbourne, Florida to South Carolina can take about 1h 53m. American Airlines provides one of the quickest options available for as low as $361. There are 492 mi between Melbourne, Florida and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Melbourne, Florida to South Carolina?

    While some choose either Melbourne - Greenville or Melbourne - Charleston, Melbourne - Charlotte Douglas is the most popular route from Melbourne, Florida to South Carolina.

  • Can I find deals for flights from Melbourne to South Carolina that include hotel bookings?

    Yes. In addition to deals on Melbourne to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to South Carolina.

  • Can I find deals for business class flights from Melbourne to South Carolina?

    Yes. Cheapflights offers flight deals from Melbourne to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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