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South Carolina

$107+ Cheap flights from Melbourne, FL (MLB) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — CHS
Jan 30 — Feb 61
Fri 1/30
Fri 2/6
1 adult, Economy
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Cheap flight deals from Melbourne to South Carolina

Cheapest flights from Melbourne to South Carolina
Explore the most affordable flight options available from Melbourne to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:20 amMLB - CLT
Nonstop1h 53mAmerican Airlines
Sun 1/411:20 amCLT - MLB
Nonstop1h 57mAmerican Airlines
Deal found 12/30$352
This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:30 amMLB - CLT
1 stop3h 55mDelta
Sun 1/48:15 amCLT - MLB
1 stop5h 51mDelta
Deal found 12/30$382
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:40 pmMLB - GSP
1 stop3h 44mAmerican Airlines
Sat 1/1010:32 amGSP - MLB
1 stop5h 19mAmerican Airlines
Deal found 12/30$443
This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:47 pmMLB - GSP
1 stop4h 45mDelta
Sat 1/105:40 amGSP - MLB
1 stop4h 50mDelta
Deal found 12/30$455

Find flight deals from Melbourne to South Carolina

Keep the following information in mind while searching for Melbourne to South Carolina flight deals. Data was last updated December 31, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$269
(Delta)

One-way from

$107
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$278
Provider with most accurate pricing for Orlando (ORL)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Orlando (ORL)-Myrtle Beach Intl flights.
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From Melbourne to South Carolina
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One-way flight from Melbourne to South Carolina
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Highest demand for flights based on searches. 10% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Melbourne to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Melbourne to South Carolina that are best for you.

Fly from

Melbourne

Fly to

South Carolina

Route

Depart

Return

Price

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

Sat 2/14

3:08 pm-8:27 pm

1 stop5h 19m

Columbia Metropolitan

Sat 2/21

5:07 pm-9:35 pm

1 stop4h 28m

$269

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Wed 5/13

5:35 pm-7:34 pm

Nonstop1h 59m

Charlotte Douglas

Sat 5/16

3:15 pm-5:05 pm

Nonstop1h 50m

$291

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Sat 1/17

4:21 pm-6:18 pm

Nonstop1h 57m

Charlotte Douglas

Sun 1/18

10:16 am-12:09 pm

Nonstop1h 53m

$292

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

Sat 2/14

3:08 pm-8:27 pm

1 stop5h 19m

Columbia Metropolitan

Thu 2/19

5:35 am-10:39 am

1 stop5h 04m

$308

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

Sat 2/14

3:08 pm-8:27 pm

1 stop5h 19m

Columbia Metropolitan

Mon 2/23

6:50 pm-10:45 pm

1 stop3h 55m

$308

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

Sun 2/15

6:00 am-9:28 am

1 stop3h 28m

Columbia Metropolitan

Sat 2/21

5:07 pm-9:35 pm

1 stop4h 28m

$308

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

Thu 2/12

6:00 am-9:28 am

1 stop3h 28m

Columbia Metropolitan

Sat 2/21

5:07 pm-9:35 pm

1 stop4h 28m

$308

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

Fri 2/13

3:08 pm-8:27 pm

1 stop5h 19m

Columbia Metropolitan

Sat 2/21

5:07 pm-9:35 pm

1 stop4h 28m

$308

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

Sat 2/14

3:08 pm-8:27 pm

1 stop5h 19m

Columbia Metropolitan

Sun 2/22

6:40 am-10:39 am

1 stop3h 59m

$308

MelbourneSavannah

MLB - SAV

MLBSAV

Melbourne

Thu 1/29

4:21 pm-9:00 pm

1 stop4h 39m

Savannah/Hilton Head

Wed 2/4

10:22 am-3:51 pm

1 stop5h 29m

$318

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 44 results
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Best time to book a flight from Melbourne to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Melbourne to South Carolina

What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $41). Flying from Melbourne, Florida to South Carolina in January is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 31, 2025.
Read through reviews of airlines operating flights from Melbourne to South Carolina, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,013 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,013 reviews
Delta
7.9
Good
8,013 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,074 reviews
Delta
7.9
Good
8,013 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Melbourne to South Carolina?

    Located just 2.7 mi from the city center, Melbourne (MLB) is the airport most travelers will use when flying to South Carolina from Melbourne.

  • How long is the flight from Melbourne, Florida to South Carolina?

    A quick flight from Melbourne, Florida to South Carolina can take about 1h 59m. Delta provides one of the quickest options available for as low as $291. There are 492 mi between Melbourne, Florida and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Melbourne, Florida to South Carolina?

    While some choose either Melbourne - Myrtle Beach Intl or Melbourne - Greenville, Melbourne - Charlotte Douglas is the most popular route from Melbourne, Florida to South Carolina.

  • Can I find deals for flights from Melbourne to South Carolina that include hotel bookings?

    Yes. In addition to deals on Melbourne to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to South Carolina.

  • Can I find deals for business class flights from Melbourne to South Carolina?

    Yes. Cheapflights offers flight deals from Melbourne to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $41). Flying from Melbourne, Florida to South Carolina in January is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Melbourne to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Melbourne to South Carolina

Discover the top 2 airlines that operate flights from Melbourne to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$276Average$377FlexibilityNo cancel feeOn-time71%
DeltaCheapest$286Average$387FlexibilityNo cancel feeOn-timeN/A

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