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South Carolina

$117+ Cheap flights from Melbourne, FL (MLB) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — CHS
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
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Find flight deals from Melbourne to South Carolina

Cheapest flights from Melbourne to South Carolina
Explore the most affordable flight options available from Melbourne to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:20 amMLB - CLT
Nonstop1h 56mAmerican Airlines
Wed 12/109:50 pmCLT - MLB
Nonstop1h 51mAmerican Airlines
Deal found 11/3$215
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:47 pmMLB - CLT
1 stop4h 55mDelta
Sun 12/146:33 amCLT - MLB
1 stop4h 03mDelta
Deal found 11/3$235
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:29 pmMLB - CLT
1 stop3h 59mDelta
Wed 12/105:27 amCLT - MLB
1 stop5h 09mDelta
Deal found 11/3$268
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:20 amMLB - CLT
Nonstop1h 56mAmerican Airlines
Mon 12/2910:30 pmCLT - MLB
Nonstop1h 42mAmerican Airlines
Deal found 11/3$274
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amMLB - CLT
1 stop4h 45mDelta
Thu 12/115:27 amCLT - MLB
1 stop5h 09mDelta
Deal found 11/4$280
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/47:20 amMLB - CLT
Nonstop2h 00mAmerican Airlines
Tue 11/119:50 pmCLT - MLB
Nonstop1h 55mAmerican Airlines
Deal found 11/3$281
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amMLB - CLT
1 stop4h 45mDelta
Mon 12/296:53 pmCLT - MLB
1 stop4h 01mDelta
Deal found 11/3$294
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:47 pmMLB - CHS
1 stop5h 03mDelta
Sun 12/146:30 amCHS - MLB
1 stop4h 06mDelta
Deal found 11/3$297
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:50 pmMLB - CLT
1 stop5h 00mDelta
Tue 11/119:47 amCLT - MLB
1 stop3h 56mDelta
Deal found 11/3$301
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:47 pmMLB - GSP
1 stop4h 53mDelta
Sat 12/135:35 amGSP - MLB
1 stop5h 01mDelta
Deal found 11/3$317
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:52 pmMLB - GSP
2 stops11h 07mAmerican Airlines
Sat 12/135:25 amGSP - MLB
1 stop6h 08mAmerican Airlines
Deal found 11/3$322
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:23 pmMLB - GSP
1 stop6h 34mAmerican Airlines
Mon 12/86:01 amGSP - MLB
1 stop6h 18mAmerican Airlines
Deal found 11/3$327

Cheap flight deals from Melbourne to South Carolina

Keep the following information in mind while searching for Melbourne to South Carolina flight deals. Data was last updated November 4, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$215
(American Airlines)

One-way from

$117
(Kiwi.com)

Popular in

August

Cheapest in

February

Average price

$187
Provider with most accurate pricing for Orlando (ORL)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Orlando (ORL)-Myrtle Beach Intl flights.
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From Melbourne to South Carolina
Search Deals
One-way flight from Melbourne to South Carolina
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($17 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Melbourne to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Melbourne to South Carolina that are best for you.

Fly from

Melbourne

Fly to

South Carolina

Route

Depart

Return

Price

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Thu 12/4

6:07 am-8:03 am

Nonstop1h 56m

Charlotte Douglas

Thu 12/11

10:35 pm-12:23 am

Nonstop1h 48m

$215

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Thu 12/11

6:47 pm-11:42 pm

1 stop4h 55m

Charlotte Douglas

Sun 12/14

6:33 am-10:36 am

1 stop4h 03m

$235

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Wed 12/17

7:20 am-9:16 am

Nonstop1h 56m

Charlotte Douglas

Mon 12/29

10:30 pm-12:12 am

Nonstop1h 42m

$274

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Thu 12/4

6:00 am-10:45 am

1 stop4h 45m

Charlotte Douglas

Thu 12/11

5:27 am-10:36 am

1 stop5h 09m

$280

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Wed 12/17

6:00 am-10:45 am

1 stop4h 45m

Charlotte Douglas

Mon 12/29

6:53 pm-10:54 pm

1 stop4h 01m

$294

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Thu 12/11

6:47 pm-11:50 pm

1 stop5h 03m

Charleston

Sun 12/14

6:30 am-10:36 am

1 stop4h 06m

$297

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Sun 12/7

6:00 am-11:45 am

1 stop5h 45m

Charleston

Tue 12/9

8:00 am-1:44 pm

1 stop5h 44m

$297

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Thu 12/11

6:47 pm-11:50 pm

1 stop5h 03m

Charleston

Sat 12/13

7:00 am-1:44 pm

1 stop6h 44m

$297

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Wed 12/10

6:47 pm-11:40 pm

1 stop4h 53m

Greenville

Sat 12/13

5:35 am-10:36 am

1 stop5h 01m

$317

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Wed 12/10

12:52 pm-11:59 pm

2 stops11h 07m

Greenville

Sat 12/13

5:25 am-11:33 am

1 stop6h 08m

$322

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 56 results
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Best time to book a flight from Melbourne to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Melbourne to South Carolina

What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $43). Flying from Melbourne, Florida to South Carolina in December is currently the most expensive (average of $88). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MLB to SC?

Find hourly flight availability from Melbourne to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 29% on flights from Melbourne, Florida to South Carolina by exploring options for tickets in the afternoon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 4, 2025.
Read through reviews of airlines operating flights from Melbourne to South Carolina, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,003 reviews
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Melbourne to South Carolina?

    Located just 2.7 mi from the city center, Melbourne (MLB) is the airport most travelers will use when flying to South Carolina from Melbourne.

  • How long is the flight from Melbourne, Florida to South Carolina?

    A quick flight from Melbourne, Florida to South Carolina can take about 1h 56m. American Airlines provides one of the quickest options available for as low as $215. There are 492 mi between Melbourne, Florida and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Melbourne, Florida to South Carolina one-way?

    One-way options have recently been found by users for as low as $117 on Allegiant Air. Other airlines that offer cheap prices include Delta from $158 and American Airlines from $204 one-way.

  • What are the most popular routes from Melbourne, Florida to South Carolina?

    While some choose either Melbourne - Charleston or Melbourne - Myrtle Beach Intl, Melbourne - Charlotte Douglas is the most popular route from Melbourne, Florida to South Carolina.

  • Can I find deals for flights from Melbourne to South Carolina that include hotel bookings?

    Yes. In addition to deals on Melbourne to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to South Carolina.

  • Can I find deals for business class flights from Melbourne to South Carolina?

    Yes. Cheapflights offers flight deals from Melbourne to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $43). Flying from Melbourne, Florida to South Carolina in December is currently the most expensive (average of $88). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Melbourne to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Melbourne to South Carolina

Discover the top 2 airlines that operate flights from Melbourne to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$276Average$415FlexibilityNo cancel feeOn-time71%
DeltaCheapest$282Average$379FlexibilityNo cancel feeOn-timeN/A

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