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South Carolina

$261+ Cheap flights from Medford (MFR) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — CHS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Medford to South Carolina

Keep the following information in mind while searching for Medford to South Carolina flight deals. Data was last updated June 12, 2025.

Round-trip from

$261
(Delta)
From Medford to South Carolina
Search Deals

Find flight deals from Medford to South Carolina

Cheapest flights from Medford to South Carolina
Explore the most affordable flight options available from Medford to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:55 amMFR - GSP
2 stops8h 46mDelta
Wed 10/13:42 pmGSP - MFR
2 stops10h 27mDelta
Deal found 6/11$261
This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/109:51 pmMFR - CLT
1 stop12h 49mMultiple Airlines
Sat 7/129:28 pmCLT - MFR
1 stop20h 58mMultiple Airlines
Deal found 6/12$268
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:55 amMFR - CLT
1 stop7h 44mDelta
Tue 12/25:20 pmCLT - MFR
1 stop9h 24mDelta
Deal found 6/11$309
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/186:35 pmMFR - CLT
2 stops12h 37mUnited Airlines
Mon 7/214:16 pmCLT - MFR
1 stop8h 10mUnited Airlines
Deal found 6/12$314
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:00 amMFR - GSP
2 stops8h 53mUnited Airlines
Wed 10/19:35 amGSP - MFR
2 stops11h 17mUnited Airlines
Deal found 6/11$361
This Alaska Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:45 amMFR - GSP
2 stops13h 16mAlaska Airlines
Tue 9/307:15 amGSP - MFR
2 stops12h 51mAlaska Airlines
Deal found 6/11$415
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/45:35 amMFR - CLT
1 stop7h 10mAmerican Airlines
Mon 7/76:17 pmCLT - MFR
1 stop7h 49mAmerican Airlines
Deal found 6/12$432
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/205:00 amMFR - CAE
2 stops25h 54mUnited Airlines
Sun 7/277:45 pmCAE - MFR
2 stops19h 07mUnited Airlines
Deal found 6/12$628
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/305:35 amMFR - GSP
2 stops11h 51mAmerican Airlines
Mon 7/74:07 pmGSP - MFR
2 stops9h 59mAmerican Airlines
Deal found 6/9$749

Cheapflights Fare Finder

Customize your flight search to find flights from Medford to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Medford to South Carolina that are best for you.

Fly from

Medford

Fly to

South Carolina

Route

Depart

Return

Price

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 9/23

5:55 am-5:41 pm

2 stops8h 46m

Greenville

Wed 10/1

3:42 pm-11:09 pm

2 stops10h 27m

$261

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Thu 7/10

9:51 pm-1:40 pm

1 stop12h 49m

Charlotte Douglas

Sat 7/12

9:28 pm-3:26 pm

1 stop20h 58m

$268

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Thu 11/27

5:55 am-4:39 pm

1 stop7h 44m

Charlotte Douglas

Tue 12/2

5:20 pm-11:44 pm

1 stop9h 24m

$309

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Fri 7/18

6:35 pm-10:12 am

2 stops12h 37m

Charlotte Douglas

Mon 7/21

4:16 pm-9:26 pm

1 stop8h 10m

$314

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 9/23

5:00 am-4:53 pm

2 stops8h 53m

Greenville

Wed 10/1

9:35 am-5:52 pm

2 stops11h 17m

$361

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 9/23

5:45 am-10:01 pm

2 stops13h 16m

Greenville

Tue 9/30

7:15 am-5:06 pm

2 stops12h 51m

$415

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Fri 7/4

5:35 am-3:45 pm

1 stop7h 10m

Charlotte Douglas

Mon 7/7

6:17 pm-11:06 pm

1 stop7h 49m

$432

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Sun 7/20

5:00 am-9:54 am

2 stops25h 54m

Columbia Metropolitan

Sun 7/27

7:45 pm-11:52 am

2 stops19h 07m

$628

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Mon 6/30

5:35 am-8:26 pm

2 stops11h 51m

Greenville

Mon 7/7

4:07 pm-11:06 pm

2 stops9h 59m

$749

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Sat 7/12

5:15 am-4:21 pm

1 stop8h 06m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 11 results
1
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Best time to book a flight from Medford to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to South Carolina

What is the cheapest month to book a flight from Medford to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Medford to South Carolina (average of $217). Flying from Medford to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to SC?

Find hourly flight availability from Medford to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Medford to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 12, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta and United Airlines from Medford to South Carolina to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,950 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Medford to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to South Carolina?

    Medford (MFR), located 3.0 mi from the city center, is the airport you fly out of when you book flights from Medford to South Carolina.

  • What are the most popular routes from Medford to South Carolina?

    The most popular flight routes from Medford to South Carolina are Medford - Greenville, Medford - Charlotte Douglas and Medford - Columbia Metropolitan.

  • Can I find deals for flights from Medford to South Carolina that include hotel bookings?

    Yes. In addition to deals on Medford to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to South Carolina.

  • Can I find deals for business class flights from Medford to South Carolina?

    Yes. Cheapflights offers flight deals from Medford to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Medford to South Carolina (average of $217). Flying from Medford to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Medford to South Carolina

Discover the top 3 airlines that operate flights from Medford to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$254Average$561FlexibilityNo cancel feeOn-time69%
DeltaCheapest$274Average$369FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$449Average$516FlexibilityNo cancel feeOn-time75%

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