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South Carolina

$210+ Cheap flights from Medford (MFR) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — CHS
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheap flight deals from Medford to South Carolina

Keep the following information in mind while searching for Medford to South Carolina flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$309
(United Airlines)

One-way from

$210
(Kiwi.com)
From Medford to South Carolina
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One-way flight from Medford to South Carolina
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Find flight deals from Medford to South Carolina

Cheapest flights from Medford to South Carolina
Explore the most affordable flight options available from Medford to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/66:37 pmMFR - CLT
2 stops12h 54mUnited Airlines
lun. 10/2010:34 amCLT - MFR
2 stops12h 55mUnited Airlines
Deal found 9/15$378
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/15:00 amMFR - CLT
1 stop7h 13mUnited Airlines
mar. 10/1411:27 amCLT - MFR
2 stops12h 02mUnited Airlines
Deal found 9/14$399
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/275:15 amMFR - GSP
2 stops12h 52mDelta
mié. 10/15:30 amGSP - MFR
2 stops13h 04mDelta
Deal found 9/13$414
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/15:30 amMFR - CLT
1 stop10h 03mAmerican Airlines
mar. 10/142:40 pmCLT - MFR
1 stop7h 44mAmerican Airlines
Deal found 9/14$439
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/186:00 amMFR - CLT
2 stops9h 53mUnited Airlines
sáb. 9/208:30 amCLT - MFR
1 stop7h 38mUnited Airlines
Deal found 9/14$492
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/276:00 amMFR - GSP
2 stops12h 18mUnited Airlines
mié. 10/14:29 pmGSP - MFR
1 stop7h 37mUnited Airlines
Deal found 9/14$519
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/46:36 pmMFR - CAE
2 stops12h 23mUnited Airlines
vie. 11/77:35 pmCAE - MFR
2 stops27h 33mUnited Airlines
Deal found 9/15$588
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/36:36 pmMFR - CLT
2 stops19h 44mUnited Airlines
jue. 11/64:17 pmCLT - MFR
1 stop7h 57mUnited Airlines
Deal found 9/15$681
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/35:15 amMFR - CLT
1 stop8h 04mDelta
jue. 11/65:30 pmCLT - MFR
1 stop9h 19mDelta
Deal found 9/15$685

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Medford to South Carolina that are best for you.

Fly from

Medford

Fly to

South Carolina

Route

Depart

Return

Price

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

dom. 2/1

5:00 am-3:16 pm

1 stop7h 16m

Charlotte Douglas

dom. 2/15

4:19 pm-9:23 pm

1 stop8h 04m

$309

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

dom. 2/1

5:21 pm-10:15 am

2 stops13h 54m

Charlotte Douglas

dom. 2/15

5:10 pm-10:47 pm

1 stop8h 37m

$314

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

mié. 10/1

5:00 am-3:13 pm

1 stop7h 13m

Charlotte Douglas

mar. 10/14

11:27 am-8:29 pm

2 stops12h 02m

$399

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

lun. 10/6

6:37 pm-10:31 am

2 stops12h 54m

Charlotte Douglas

lun. 10/20

4:30 pm-9:06 pm

1 stop7h 36m

$409

MedfordGreenville

MFR - GSP

MFRGSP

Medford

sáb. 9/27

5:15 am-9:07 pm

2 stops12h 52m

Greenville

mié. 10/1

5:30 am-3:34 pm

2 stops13h 04m

$414

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

mié. 10/1

5:30 am-6:33 pm

1 stop10h 03m

Charlotte Douglas

mar. 10/14

2:40 pm-7:24 pm

1 stop7h 44m

$439

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

lun. 10/6

4:08 pm-5:00 am

1 stop9h 52m

Charlotte Douglas

lun. 10/20

6:22 pm-2:01 pm

1 stop22h 39m

$439

MedfordGreenville

MFR - GSP

MFRGSP

Medford

sáb. 9/27

6:00 am-9:18 pm

2 stops12h 18m

Greenville

mié. 10/1

4:29 pm-9:06 pm

1 stop7h 37m

$519

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

lun. 11/3

6:36 pm-5:20 pm

2 stops19h 44m

Charlotte Douglas

jue. 11/6

4:17 pm-9:14 pm

1 stop7h 57m

$681

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

lun. 11/3

5:15 am-4:19 pm

1 stop8h 04m

Charlotte Douglas

jue. 11/6

5:30 pm-11:49 pm

1 stop9h 19m

$685

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 13 results
1
2

Best time to book a flight from Medford to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to South Carolina

What is the cheapest month to book a flight from Medford to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Medford to South Carolina (average of $217). Flying from Medford to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to SC?

Find hourly flight availability from Medford to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

When flying from Medford to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated septiembre 15, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Delta, and United Airlines from Medford to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Overall

8.0

Comfort

7.8

Boarding

8.1

Crew

8.5

Food

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Overall

8.0

Comfort

7.8

Boarding

8.1

Crew

8.5

Food

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Delta
8.0
Very good
7,954 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Overall

8.0

Comfort

7.8

Boarding

8.1

Crew

8.5

Food

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,929 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Overall

8.0

Comfort

7.8

Boarding

8.1

Crew

8.5

Food

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Medford to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to South Carolina?

    Medford (MFR), located 3.0 mi from the city center, is the airport you fly out of when you book flights from Medford to South Carolina.

  • How long is the flight from Medford to South Carolina?

    Airlines like United Airlines and Delta fly from Medford to South Carolina in about 7h 16m. The time it takes to get you to your destination can typically vary by up to 6h 38m. Airlines will cover a distance of 2286 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Medford to South Carolina?

    The most popular flight routes from Medford to South Carolina are Medford - Charlotte Douglas, Medford - Columbia Metropolitan and Medford - Greenville.

  • Can I find deals for flights from Medford to South Carolina that include hotel bookings?

    Yes. In addition to deals on Medford to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to South Carolina.

  • Can I find deals for business class flights from Medford to South Carolina?

    Yes. Cheapflights offers flight deals from Medford to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Medford to South Carolina (average of $217). Flying from Medford to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Medford to South Carolina

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Top 3 airlines flying from Medford to South Carolina

Discover the top 3 airlines that operate flights from Medford to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$234Average$564FlexibilityNo cancel feeOn-time69%
DeltaCheapest$274Average$369FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$353Average$516FlexibilityNo cancel feeOn-time75%

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