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South Carolina

$264+ Cheap flights from Medford (MFR) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — CHS
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Medford to South Carolina

Keep the following information in mind while searching for Medford to South Carolina flight deals. Data was last updated July 31, 2025.

Round-trip from

$402
(United Airlines)

One-way from

$264
(United Airlines)
From Medford to South Carolina
Search Deals
One-way flight from Medford to South Carolina
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Find flight deals from Medford to South Carolina

Cheapest flights from Medford to South Carolina
Explore the most affordable flight options available from Medford to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/136:00 amMFR - CLT
2 stops12h 57mUnited Airlines
Sun 8/174:16 pmCLT - MFR
1 stop8h 10mUnited Airlines
Deal found 7/29$402
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:00 amMFR - GSP
1 stop6h 58mUnited Airlines
Tue 8/264:30 pmGSP - MFR
1 stop7h 34mUnited Airlines
Deal found 7/30$405
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/146:35 pmMFR - CAE
2 stops12h 19mUnited Airlines
Mon 8/1810:29 amCAE - MFR
2 stops13h 57mUnited Airlines
Deal found 7/30$415
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/195:33 amMFR - CLT
1 stop9h 27mAmerican Airlines
Sun 8/246:21 pmCLT - MFR
1 stop7h 56mAmerican Airlines
Deal found 7/31$440
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:33 amMFR - GSP
2 stops13h 57mAmerican Airlines
Tue 8/267:41 amGSP - MFR
2 stops14h 48mAmerican Airlines
Deal found 7/29$455
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:12 pmMFR - CLT
2 stops13h 10mMultiple Airlines
Sun 10/129:52 pmCLT - MFR
3 stops20h 39mMultiple Airlines
Deal found 7/30$476
This Alaska Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1912:40 pmMFR - CLT
2 stops17h 36mAlaska Airlines
Sun 8/243:05 pmCLT - MFR
2 stops23h 20mAlaska Airlines
Deal found 7/31$479
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/135:15 amMFR - CLT
1 stop8h 04mDelta
Sun 8/175:29 pmCLT - MFR
1 stop9h 24mDelta
Deal found 7/29$494
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amMFR - GSP
2 stops14h 54mDelta
Thu 11/137:15 amGSP - MFR
2 stops12h 29mDelta
Deal found 7/31$519

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Medford to South Carolina that are best for you.

Fly from

Medford

Fly to

South Carolina

Route

Depart

Return

Price

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Wed 8/13

6:00 am-9:57 pm

2 stops12h 57m

Charlotte Douglas

Sun 8/17

4:16 pm-9:26 pm

1 stop8h 10m

$402

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 8/23

5:00 am-2:58 pm

1 stop6h 58m

Greenville

Tue 8/26

4:30 pm-9:04 pm

1 stop7h 34m

$405

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Thu 8/14

6:35 pm-9:54 am

2 stops12h 19m

Columbia Metropolitan

Mon 8/18

10:29 am-9:26 pm

2 stops13h 57m

$415

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Tue 8/19

5:33 am-6:00 pm

1 stop9h 27m

Charlotte Douglas

Sun 8/24

6:21 pm-11:17 pm

1 stop7h 56m

$440

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 8/23

5:33 am-10:30 pm

2 stops13h 57m

Greenville

Tue 8/26

7:41 am-7:29 pm

2 stops14h 48m

$455

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Fri 10/10

5:12 pm-9:22 am

2 stops13h 10m

Charlotte Douglas

Sun 10/12

9:52 pm-3:31 pm

3 stops20h 39m

$476

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Tue 8/19

12:40 pm-9:16 am

2 stops17h 36m

Charlotte Douglas

Sun 8/24

3:05 pm-11:25 am

2 stops23h 20m

$479

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Wed 8/13

5:15 am-4:19 pm

1 stop8h 04m

Charlotte Douglas

Sun 8/17

5:29 pm-11:53 pm

1 stop9h 24m

$494

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Thu 11/6

6:00 am-11:54 pm

2 stops14h 54m

Greenville

Thu 11/13

7:15 am-4:44 pm

2 stops12h 29m

$519

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Tue 8/5

1:00 pm-10:59 pm

1 stop6h 59m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Medford to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to South Carolina

What is the cheapest month to book a flight from Medford to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Medford to South Carolina (average of $217). Flying from Medford to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to SC?

Find hourly flight availability from Medford to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Medford to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 31, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Delta, and United Airlines from Medford to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Boarding

8.1

Food

7.1

Overall

8.0

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Boarding

8.1

Food

7.1

Overall

8.0

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Delta
8.0
Very good
7,981 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Boarding

8.1

Food

7.1

Overall

8.0

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
United Airlines
7.4
Good
8,900 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Boarding

8.1

Food

7.1

Overall

8.0

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Boarding

8.1

Food

7.1

Overall

8.0

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.

Related info for your journey

Find useful and relevant information for your journey from Medford to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to South Carolina?

    Medford (MFR), located 3.0 mi from the city center, is the airport you fly out of when you book flights from Medford to South Carolina.

  • What are the most popular routes from Medford to South Carolina?

    The most popular flight routes from Medford to South Carolina are Medford - Greenville, Medford - Columbia Metropolitan and Medford - Charlotte Douglas.

  • Can I find deals for flights from Medford to South Carolina that include hotel bookings?

    Yes. In addition to deals on Medford to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to South Carolina.

  • Can I find deals for business class flights from Medford to South Carolina?

    Yes. Cheapflights offers flight deals from Medford to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Medford to South Carolina (average of $217). Flying from Medford to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Medford to South Carolina

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Top 3 airlines flying from Medford to South Carolina

Discover the top 3 airlines that operate flights from Medford to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$254Average$562FlexibilityNo cancel feeOn-time69%
DeltaCheapest$274Average$369FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$449Average$516FlexibilityNo cancel feeOn-time75%

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