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$413+ Cheap flights from La Crosse (LSE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/5. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — CHS
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from La Crosse to South Carolina

Keep the following information in mind while searching for La Crosse to South Carolina flight deals. Data was last updated junio 12, 2025.

Round-trip from

$447
(American Airlines)

One-way from

$413
(American Airlines)
From La Crosse to South Carolina
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One-way flight from La Crosse to South Carolina
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Find flight deals from La Crosse to South Carolina

Cheapest flights from La Crosse to South Carolina
Explore the most affordable flight options available from La Crosse to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/94:40 pmLSE - CHS
1 stop6h 19mAmerican Airlines
jue. 8/287:56 pmCHS - LSE
1 stop4h 23mAmerican Airlines
Deal found 6/11$447
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/264:35 pmLSE - CLT
1 stop4h 05mAmerican Airlines
lun. 6/306:04 pmCLT - LSE
1 stop6h 26mAmerican Airlines
Deal found 6/10$518

Cheapflights Fare Finder

Customize your flight search to find flights from La Crosse to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from La Crosse to South Carolina that are best for you.

Fly from

La Crosse

Fly to

South Carolina

Route

Depart

Return

Price

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

mié. 7/9

4:40 pm-11:59 pm

1 stop6h 19m

Charleston

jue. 8/28

7:56 pm-11:19 pm

1 stop4h 23m

$447

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

jue. 6/26

4:35 pm-9:40 pm

1 stop4h 05m

Charlotte Douglas

lun. 6/30

6:04 pm-11:30 pm

1 stop6h 26m

$518

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

sáb. 7/5

6:00 am-12:27 pm

1 stop5h 27m

$413

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from La Crosse to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from La Crosse to South Carolina

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated junio 12, 2025.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Overall

7.2

Food

6.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Overall

7.2

Food

6.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from La Crosse to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from La Crosse to South Carolina?

    Most people fly from La Crosse (LSE) if they book a flight from La Crosse to South Carolina. La Crosse is conveniently located just 5.4 mi from La Crosse’s city center.

  • What are the most popular routes from La Crosse to South Carolina?

    Most travelers choose La Crosse - Charlotte Douglas, La Crosse - Charleston or La Crosse - Greenville when deciding on the best route from La Crosse to South Carolina.

  • Can I find deals for flights from La Crosse to South Carolina that include hotel bookings?

    Yes. In addition to deals on La Crosse to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to South Carolina.

  • Can I find deals for business class flights from La Crosse to South Carolina?

    Yes. Cheapflights offers flight deals from La Crosse to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from La Crosse to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from La Crosse to South Carolina (average of $217). Flying from La Crosse to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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