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South Carolina

$272+ Cheap flights from Italy to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — CHS
Feb 21 — Feb 281
Sat 2/21
Sat 2/28
1 adult, Economy
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Cheap flight deals from Italy to South Carolina

Cheapest flights from Italy to South Carolina
Explore the most affordable flight options available from Italy to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 22, 2026.

This Finnair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:50 pm
MXP
-
CLT
1 stop24h 20m
Multiple Airlines
Thu 6/185:55 pm
CLT
-
MXP
1 stop17h 35m
Multiple Airlines
Deal found 1/20$511
This Finnair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:30 pm
LIN
-
CLT
1 stop24h 40m
Multiple Airlines
Thu 6/185:55 pm
CLT
-
LIN
1 stop15h 05m
Multiple Airlines
Deal found 1/20$514
This Finnair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:50 am
VCE
-
CLT
2 stops36h 15m
Multiple Airlines
Mon 9/145:55 pm
CLT
-
VCE
1 stop13h 55m
Multiple Airlines
Deal found 1/20$531
This Finnair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:50 am
VCE
-
CLT
2 stops33h 25m
Finnair
Mon 9/145:55 pm
CLT
-
VCE
2 stops18h 35m
Finnair
Deal found 1/20$551
This lol.travel deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:35 am
VCE
-
CLT
1 stop14h 20m
Multiple Airlines
Sat 5/3011:45 pm
CLT
-
VCE
1 stop16h 20m
Multiple Airlines
Deal found 1/21$580
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1210:25 am
MXP
-
CLT
1 stop16h 45m
American Airlines
Thu 2/198:20 pm
CLT
-
MXP
1 stop14h 00m
American Airlines
Deal found 1/20$643
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:20 pm
MXP
-
GSP
1 stop28h 35m
American Airlines
Sun 9/278:24 pm
GSP
-
MXP
2 stops21h 16m
American Airlines
Deal found 1/19$643
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:25 am
MXP
-
CLT
1 stop16h 18m
American Airlines
Mon 3/1611:55 pm
CLT
-
MXP
1 stop14h 55m
American Airlines
Deal found 1/20$646
This Finnair deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2910:25 am
MXP
-
CLT
1 stop17h 48m
Multiple Airlines
Fri 2/68:25 pm
CLT
-
MXP
1 stop15h 55m
Multiple Airlines
Deal found 1/22$648
This lol.travel deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:35 am
VCE
-
CLT
2 stops33h 15m
British Airways
Sat 5/304:41 pm
CLT
-
VCE
1 stop11h 14m
British Airways
Deal found 1/21$648
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:35 am
LIN
-
CLT
1 stop17h 20m
American Airlines
Mon 3/167:20 pm
CLT
-
LIN
1 stop16h 00m
American Airlines
Deal found 1/20$650
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/298:30 pm
VCE
-
CLT
1 stop25h 35m
American Airlines
Mon 2/28:25 pm
CLT
-
VCE
1 stop17h 55m
American Airlines
Deal found 1/20$651

Find flight deals from Italy to South Carolina

Keep the following information in mind while searching for Italy to South Carolina flight deals. Data was last updated January 22, 2026.

Round-trip from

$511
(Finnair)

One-way from

$272
(Kiwi.com)
From Italy to South Carolina
Search Deals
One-way flight from Italy to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from Italy to South Carolina that are best for you.

Fly from

Italy

Fly to

South Carolina

Route

Depart

Return

Price

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Wed 6/10

6:50 pm-1:10 pm

1 stop24h 20m

Charlotte Douglas

Thu 6/18

5:55 pm-5:30 pm

1 stop17h 35m

$511

MilanCharlotte

LIN - CLT

LINCLT

Milan Linate

Wed 6/10

6:30 pm-1:10 pm

1 stop24h 40m

Charlotte Douglas

Thu 6/18

5:55 pm-3:00 pm

1 stop15h 05m

$514

VeniceCharlotte

VCE - CLT

VCECLT

Venice Marco Polo

Fri 5/22

7:35 am-3:55 pm

1 stop14h 20m

Charlotte Douglas

Sat 5/30

11:45 pm-10:05 pm

1 stop16h 20m

$580

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Thu 2/12

10:25 am-9:10 pm

1 stop16h 45m

Charlotte Douglas

Thu 2/19

8:20 pm-4:20 pm

1 stop14h 00m

$643

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Wed 4/22

11:05 am-9:18 pm

1 stop16h 13m

Charlotte Douglas

Mon 5/4

11:40 pm-5:45 pm

1 stop12h 05m

$646

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Wed 4/22

11:05 am-9:52 pm

1 stop16h 47m

Charlotte Douglas

Mon 5/4

8:15 pm-1:45 pm

1 stop11h 30m

$648

VeniceCharlotte

VCE - CLT

VCECLT

Venice Marco Polo

Fri 5/22

7:35 am-10:50 am

2 stops33h 15m

Charlotte Douglas

Sat 5/30

4:41 pm-9:55 am

1 stop11h 14m

$648

MilanCharlotte

LIN - CLT

LINCLT

Milan Linate

Wed 3/11

7:35 am-7:55 pm

1 stop17h 20m

Charlotte Douglas

Mon 3/16

7:20 pm-4:20 pm

1 stop16h 00m

$650

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 3/25

10:40 am-8:35 am

2 stops26h 55m

Charlotte Douglas

Mon 4/13

8:15 pm-3:10 pm

1 stop12h 55m

$652

MilanCharlotte

LIN - CLT

LINCLT

Milan Linate

Thu 2/12

7:15 am-6:55 pm

1 stop17h 40m

Charlotte Douglas

Thu 2/19

8:20 pm-3:55 pm

1 stop13h 35m

$652

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 60 results
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Best time to book a flight from Italy to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 22, 2026.
Read reviews from past customers who have flown Lufthansa from Italy to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Lufthansa
6.8
Okay
7,738 reviews

Comfort

6.8

Crew

7.6

Overall

6.8

Boarding

7.0

Food

6.3

Entertainment

6.4

Reviews

1 / 20
4.0
Okay

Djermouli,Dec 2025

FRA - SFO

I’m sorry the worst airline united food sales I’m diabetic plus high cholesterol pls seats it’s not comfortable plus screen tv broke I try to charge my phone don’t work I’m not flying with united airlines
Lufthansa
6.8
Okay
7,738 reviews
Lufthansa
6.8
Okay
7,738 reviews

Comfort

6.8

Crew

7.6

Overall

6.8

Boarding

7.0

Food

6.3

Entertainment

6.4

Reviews

1 / 20
4.0
Okay

Djermouli,Dec 2025

FRA - SFO

I’m sorry the worst airline united food sales I’m diabetic plus high cholesterol pls seats it’s not comfortable plus screen tv broke I try to charge my phone don’t work I’m not flying with united airlines

Related info for your journey

Find useful and relevant information for your journey from Italy to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Italy to South Carolina?

    A quick flight from Italy to South Carolina can take about 16h 45m. American Airlines provides one of the quickest options available for as low as $643. The distance from Italy to South Carolina is about 4519 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Italy to South Carolina that include hotel bookings?

    Yes. In addition to deals on Italy to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to South Carolina.

  • Can I find deals for business class flights from Italy to South Carolina?

    Yes. Cheapflights offers flight deals from Italy to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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