$330+ Cheap flights from Italy to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — CHS
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from Italy to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Italy to South CarolinaExplore the most affordable flight options available from Italy to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from Italy to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Trip.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:15 am
VCE
- CLT
2 stops23h 38m
Multiple Airlines
Tue 4/1410:13 am
CLT
- VCE
2 stops18h 17m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$633
This lol.travel deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/302:15 pm
FCO
- CLT
Nonstop10h 40m
British Airways
Sun 4/128:05 pm
CLT
- FCO
1 stop15h 00m
British Airways
Deal found 3/8![British Airways logo]()
$690
This Booking.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:00 pm
MXP
- CLT
2 stops33h 59m
Multiple Airlines
Fri 4/2410:16 am
CLT
- MXP
2 stops27h 34m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$694
This Finnair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:55 am
MXP
- CLT
2 stops27h 40m
Multiple Airlines
Mon 12/1410:30 pm
CLT
- MXP
1 stop15h 20m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$713
This Finnair deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:20 am
MXP
- CLT
2 stops28h 16m
Multiple Airlines
Mon 4/205:55 pm
CLT
- MXP
1 stop17h 50m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$714
This Finnair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:50 am
VCE
- CLT
2 stops28h 43m
Multiple Airlines
Mon 9/148:20 pm
CLT
- VCE
1 stop17h 40m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$715
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:20 am
MXP
- CLT
2 stops17h 33m
American Airlines
Sun 11/228:15 pm
CLT
- MXP
1 stop17h 45m
American Airlines
Deal found 3/5![American Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:20 pm
MXP
- CHS
1 stop35h 57m
American Airlines
Tue 9/224:46 pm
CHS
- MXP
2 stops24h 54m
American Airlines
Deal found 3/6![American Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:00 pm
MXP
- CLT
1 stop14h 59m
American Airlines
Fri 4/2411:45 pm
CLT
- MXP
1 stop12h 45m
American Airlines
Deal found 3/5![American Airlines logo]()
$717
This Flighttix deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:15 pm
FCO
- CLT
Nonstop10h 40m
British Airways
Tue 4/2811:45 pm
CLT
- FCO
1 stop14h 20m
British Airways
Deal found 3/6![British Airways logo]()
$717
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:15 pm
VCE
- CLT
1 stop18h 04m
American Airlines
Mon 9/1411:05 pm
CLT
- VCE
1 stop14h 55m
American Airlines
Deal found 3/6![American Airlines logo]()
$717
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:40 am
NAP
- CLT
1 stop35h 20m
American Airlines
Mon 4/2011:45 pm
CLT
- NAP
1 stop16h 15m
American Airlines
Deal found 3/8![American Airlines logo]()
$718
Best flights from Italy to South CarolinaDiscover carefully curated flight deals from Italy to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from Italy to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This Finnair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:50 am
VCE
- CLT
2 stops28h 43m
Multiple Airlines
Mon 9/148:20 pm
CLT
- VCE
1 stop17h 40m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$715
This British Airways deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:00 pm
MXP
- CLT
1 stop14h 59m
British Airways
Wed 4/2911:45 pm
CLT
- MXP
1 stop15h 05m
British Airways
Deal found 3/8![British Airways logo]()
$717
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:40 am
NAP
- CLT
1 stop35h 20m
American Airlines
Mon 4/2011:45 pm
CLT
- NAP
1 stop16h 15m
American Airlines
Deal found 3/8![American Airlines logo]()
$718
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:05 am
VCE
- CLT
1 stop15h 13m
Delta
Tue 4/145:51 pm
CLT
- VCE
2 stops13h 29m
Delta
Deal found 3/6![Delta logo]()
$724
This Finnair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:50 am
VCE
- CLT
2 stops30h 14m
Finnair
Mon 9/145:35 pm
CLT
- VCE
2 stops18h 55m
Finnair
Deal found 3/6![Finnair logo]()
$724
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:30 pm
FCO
- CHS
2 stops34h 30m
United Airlines
Tue 3/318:00 am
CHS
- FCO
1 stop17h 55m
United Airlines
Deal found 3/5![United Airlines logo]()
$727
This Gotogate deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:50 am
LIN
- CLT
1 stop12h 55m
Lufthansa
Fri 4/246:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Deal found 3/7![Lufthansa logo]()
$750
This Iberia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:50 am
LIN
- CLT
2 stops17h 42m
Iberia
Thu 4/233:35 pm
CLT
- LIN
1 stop13h 25m
Iberia
Deal found 3/9![Iberia logo]()
$758
This Turkish Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:55 am
MXP
- CHS
2 stops42h 08m
Turkish Airlines
Fri 3/278:58 pm
CHS
- MXP
2 stops29h 42m
Turkish Airlines
Deal found 3/6![Turkish Airlines logo]()
$988
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:20 am
FCO
- GSP
1 stop14h 44m
Brussels Airlines
Fri 7/32:55 pm
GSP
- FCO
1 stop11h 20m
Brussels Airlines
Deal found 3/5![Brussels Airlines logo]()
$999
This KLM deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:40 am
FCO
- GSP
1 stop26h 46m
KLM
Sat 3/285:38 pm
GSP
- FCO
1 stop31h 57m
KLM
Deal found 3/8![KLM logo]()
$1,020
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:15 pm
VCE
- CLT
1 stop16h 19m
American Airlines
Mon 9/1411:05 pm
CLT
- VCE
1 stop14h 55m
American Airlines
Deal found 3/5![American Airlines logo]()
$718
This Finnair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:00 am
MXP
- CLT
1 stop16h 52m
Multiple Airlines
Fri 4/2411:45 pm
CLT
- MXP
1 stop12h 45m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$719
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2510:05 am
FCO
- CLT
2 stops17h 33m
Delta
Mon 4/135:51 pm
CLT
- FCO
2 stops14h 34m
Delta
Deal found 3/5![Delta logo]()
$734
This British Airways deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3012:15 pm
FCO
- CLT
1 stop14h 23m
British Airways
Sun 4/1211:45 pm
CLT
- FCO
1 stop13h 35m
British Airways
Deal found 3/5![British Airways logo]()
$734
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:00 am
NAP
- CLT
2 stops23h 57m
United Airlines
Sun 4/56:00 am
CLT
- NAP
2 stops19h 00m
United Airlines
Deal found 3/7![United Airlines logo]()
$746
This Iberia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:50 am
LIN
- CLT
2 stops17h 42m
Iberia
Fri 4/243:35 pm
CLT
- LIN
1 stop22h 00m
Iberia
Deal found 3/5![Iberia logo]()
$760
This Lufthansa deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/301:20 pm
FCO
- CLT
2 stops16h 37m
Lufthansa
Sun 4/1210:34 am
CLT
- FCO
1 stop15h 21m
Lufthansa
Deal found 3/9![Lufthansa logo]()
$767
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:05 am
MXP
- CLT
1 stop19h 40m
American Airlines
Sun 4/268:05 pm
CLT
- MXP
1 stop16h 30m
American Airlines
Deal found 3/5![American Airlines logo]()
$723
This British Airways deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:15 pm
FCO
- CHS
1 stop15h 44m
British Airways
Mon 4/277:13 pm
CHS
- FCO
2 stops16h 12m
British Airways
Deal found 3/6![British Airways logo]()
$734
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:00 am
MXP
- CLT
1 stop19h 49m
Delta
Sun 4/2612:49 pm
CLT
- MXP
2 stops17h 16m
Delta
Deal found 3/5![Delta logo]()
$739
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/211:15 pm
NAP
- CLT
2 stops16h 42m
United Airlines
Tue 4/286:15 am
CLT
- NAP
2 stops18h 45m
United Airlines
Deal found 3/7![United Airlines logo]()
$746
This British Airways deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:55 am
FCO
- GSP
2 stops17h 08m
Multiple Airlines
Tue 4/287:00 am
GSP
- FCO
1 stop18h 05m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$755
This Lufthansa deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/309:45 am
MXP
- CHS
1 stop20h 14m
Lufthansa
Mon 4/62:58 pm
CHS
- MXP
2 stops13h 37m
Lufthansa
Deal found 3/7![Lufthansa logo]()
$772
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:25 am
LIN
- CLT
1 stop14h 30m
American Airlines
Mon 5/411:45 pm
CLT
- LIN
1 stop13h 10m
American Airlines
Deal found 3/7![American Airlines logo]()
$724
This British Airways deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:15 pm
FCO
- GSP
1 stop13h 46m
British Airways
Tue 4/287:00 am
GSP
- FCO
1 stop18h 05m
British Airways
Deal found 3/7![British Airways logo]()
$742
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:40 am
MXP
- CHS
1 stop13h 20m
Delta
Wed 4/812:29 pm
CHS
- MXP
2 stops15h 56m
Delta
Deal found 3/6![Delta logo]()
$746
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:00 am
MXP
- CLT
2 stops15h 45m
United Airlines
Mon 4/2010:13 am
CLT
- MXP
2 stops15h 17m
United Airlines
Deal found 3/9![United Airlines logo]()
$747
This Expedia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:45 am
FCO
- GSP
1 stop17h 02m
Lufthansa
Thu 4/307:35 pm
GSP
- FCO
2 stops13h 30m
Lufthansa
Deal found 3/9![Lufthansa logo]()
$781
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:30 pm
VCE
- CLT
2 stops24h 19m
American Airlines
Mon 5/48:05 pm
CLT
- VCE
1 stop31h 35m
American Airlines
Deal found 3/6![American Airlines logo]()
$728
Last-minute flights from Italy to South CarolinaDiscover last-minute flight deals from Italy to South Carolina. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from Italy to South Carolina. Data last updated March 10, 2026 and is based on user searches.
This lol.travel deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/302:15 pm
FCO
- CLT
Nonstop10h 40m
British Airways
Sun 4/128:05 pm
CLT
- FCO
1 stop15h 00m
British Airways
Deal found 3/8![British Airways logo]()
$690
This lol.travel deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/301:40 pm
VCE
- CLT
1 stop15h 45m
British Airways
Sun 4/54:25 pm
CLT
- VCE
1 stop11h 30m
British Airways
Deal found 3/9![British Airways logo]()
$724
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:40 pm
VCE
- CLT
1 stop15h 45m
American Airlines
Tue 4/711:45 pm
CLT
- VCE
1 stop11h 55m
American Airlines
Deal found 3/6![American Airlines logo]()
$717
This Trip.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:15 am
VCE
- CLT
2 stops23h 38m
Multiple Airlines
Tue 4/1410:13 am
CLT
- VCE
2 stops18h 17m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$633
This Booking.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:00 pm
MXP
- CLT
2 stops33h 59m
Multiple Airlines
Fri 4/2410:16 am
CLT
- MXP
2 stops27h 34m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$694
This Finnair deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:20 am
MXP
- CLT
2 stops28h 16m
Multiple Airlines
Mon 4/205:55 pm
CLT
- MXP
1 stop17h 50m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$714
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:00 pm
MXP
- CLT
1 stop14h 59m
American Airlines
Fri 4/2411:45 pm
CLT
- MXP
1 stop12h 45m
American Airlines
Deal found 3/6![American Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:40 am
NAP
- CLT
1 stop19h 05m
American Airlines
Mon 4/204:42 pm
CLT
- NAP
2 stops23h 18m
American Airlines
Deal found 3/8![American Airlines logo]()
$718
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:00 am
MXP
- CLT
1 stop16h 52m
American Airlines
Thu 4/2311:45 pm
CLT
- MXP
1 stop17h 50m
American Airlines
Deal found 3/9![American Airlines logo]()
$720
This lol.travel deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:00 am
MXP
- CLT
1 stop16h 52m
Finnair
Fri 4/248:10 am
CLT
- MXP
1 stop18h 55m
Finnair
Deal found 3/7![Finnair logo]()
$724
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:05 am
MXP
- CLT
1 stop19h 40m
American Airlines
Sun 4/268:05 pm
CLT
- MXP
1 stop16h 30m
American Airlines
Deal found 3/5![American Airlines logo]()
$723
This Flighttix deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:15 pm
FCO
- CLT
Nonstop10h 40m
British Airways
Tue 4/2811:45 pm
CLT
- FCO
1 stop14h 20m
British Airways
Deal found 3/6![British Airways logo]()
$717
One-way flights from Italy to South CarolinaSearch for one-way flight options from Italy to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from Italy to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:45 pm
FCO
- CLT
3 stops33h 14m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:45 pm
FCO
- CLT
3 stops33h 14m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:05 pm
FCO
- CLT
3 stops56h 33m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:15 pm
MXP
- CLT
2 stops37h 44m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:40 pm
BGY
- CLT
2 stops38h 25m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:50 pm
LIN
- CLT
2 stops33h 09m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:45 pm
FCO
- CHS
3 stops44h 23m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:45 am
FCO
- CLT
2 stops37h 29m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:35 am
MXP
- CHS
2 stops30h 33m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:20 am
MXP
- CLT
2 stops22h 39m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:05 pm
MXP
- CLT
2 stops16h 54m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:15 pm
MXP
- CHS
2 stops48h 53m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$368
Find flight deals from Italy to South Carolina
Keep the following information in mind while searching for Italy to South Carolina flight deals. Data was last updated March 10, 2026.
Round-trip from | $633 (Trip.com) |
|---|---|
One-way from | $321 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Italy to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Italy to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
VeniceCharlotte
VCE - CLT
VCECLT
Venice Marco Polo
Mon 8/24
9:50 am-8:33 am
2 stops28h 43m
Charlotte Douglas
Mon 9/14
8:20 pm-8:00 pm
1 stop17h 40m
$715
MilanCharlotte
MXP - CLT
MXPCLT
Milan Malpensa
Wed 4/22
3:00 pm-11:59 pm
1 stop14h 59m
Charlotte Douglas
Wed 4/29
11:45 pm-8:50 pm
1 stop15h 05m
$717
NaplesCharlotte
NAP - CLT
NAPCLT
Naples
Thu 4/16
7:40 am-1:00 pm
1 stop35h 20m
Charlotte Douglas
Mon 4/20
11:45 pm-10:00 pm
1 stop16h 15m
$718
VeniceCharlotte
VCE - CLT
VCECLT
Venice Marco Polo
Mon 8/24
12:15 pm-10:34 pm
1 stop16h 19m
Charlotte Douglas
Mon 9/14
11:05 pm-8:00 pm
1 stop14h 55m
$718
MilanCharlotte
MXP - CLT
MXPCLT
Milan Malpensa
Thu 4/16
11:00 am-9:52 pm
1 stop16h 52m
Charlotte Douglas
Fri 4/24
11:45 pm-6:30 pm
1 stop12h 45m
$719
MilanCharlotte
MXP - CLT
MXPCLT
Milan Malpensa
Sun 4/19
7:05 am-8:45 pm
1 stop19h 40m
Charlotte Douglas
Sun 4/26
8:05 pm-6:35 pm
1 stop16h 30m
$723
VeniceCharlotte
VCE - CLT
VCECLT
Venice Marco Polo
Thu 4/9
11:05 am-8:18 pm
1 stop15h 13m
Charlotte Douglas
Tue 4/14
5:51 pm-1:20 pm
2 stops13h 29m
$724
VeniceCharlotte
VCE - CLT
VCECLT
Venice Marco Polo
Mon 8/24
9:50 am-10:04 am
2 stops30h 14m
Charlotte Douglas
Mon 9/14
5:35 pm-6:30 pm
2 stops18h 55m
$724
MilanCharlotte
LIN - CLT
LINCLT
Milan Linate
Sat 5/2
7:25 am-3:55 pm
1 stop14h 30m
Charlotte Douglas
Mon 5/4
11:45 pm-6:55 pm
1 stop13h 10m
$724
RomeCharleston
FCO - CHS
FCOCHS
Rome Fiumicino
Tue 3/24
1:30 pm-7:00 pm
2 stops34h 30m
Charleston
Tue 3/31
8:00 am-7:55 am
1 stop17h 55m
$727
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Italy to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Italy with our price prediction graph.
VCE-CLT
FCO-CLT
MXP-CLT
MXP-CHS
NAP-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Italy to South Carolina
IT0-USSC
VCE-CLT
FCO-CLT
MXP-CLT
MXP-CHS
No data available for this route at this time. Please check back soon.
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