South Carolina

$320+ Cheap flights from Italy to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — CHS
Aug 18 — Aug 251
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Italy to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Italy to South Carolina

Keep the following information in mind while searching for Italy to South Carolina flight deals. Data was last updated August 13, 2025.

Round-trip from

$564
(Kiwi.com)

One-way from

$320
(Trip.com)
From Italy to South Carolina
One-way flight from Italy to South Carolina

Find flight deals from Italy to South Carolina

Cheapest flights from Italy to South Carolina
Explore the most affordable flight options available from Italy to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/47:15 amFCO - CLT
2 stops36h 29mMultiple Airlines
Thu 9/115:45 amCLT - FCO
1 stop26h 45mMultiple Airlines
Deal found 8/11$564
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:05 pmFCO - CLT
1 stop34h 31mMultiple Airlines
Sun 10/125:45 amCLT - FCO
1 stop26h 45mMultiple Airlines
Deal found 8/11$577
This Mytrip deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/115:55 amMXP - CLT
2 stops23h 41mMultiple Airlines
Mon 9/159:10 amCLT - MXP
2 stops28h 05mMultiple Airlines
Deal found 8/11$585
This Mytrip deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/311:30 amFCO - CLT
2 stops17h 50mMultiple Airlines
Wed 9/109:10 amCLT - FCO
2 stops18h 05mMultiple Airlines
Deal found 8/11$590
This Trip.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/95:50 amMXP - CLT
2 stops23h 46mMultiple Airlines
Tue 9/169:10 amCLT - MXP
2 stops27h 30mMultiple Airlines
Deal found 8/12$597
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/137:05 pmFCO - CLT
1 stop24h 53mMultiple Airlines
Sun 10/195:45 amCLT - FCO
1 stop26h 45mMultiple Airlines
Deal found 8/11$610
This Mytrip deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2512:15 pmMXP - CLT
2 stops17h 21mMultiple Airlines
Thu 10/29:10 amCLT - MXP
2 stops18h 50mMultiple Airlines
Deal found 8/11$612
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/238:20 pmMXP - CLT
2 stops33h 09mMultiple Airlines
Mon 10/2712:20 pmCLT - MXP
3 stops30h 15mMultiple Airlines
Deal found 8/13$613
This Mytrip deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:05 amLIN - CLT
3 stops22h 31mMultiple Airlines
Thu 10/29:10 amCLT - LIN
3 stops21h 10mMultiple Airlines
Deal found 8/11$615
This lol.travel deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/119:10 amMXP - CLT
2 stops20h 49mUnited Airlines
Mon 9/1511:20 amCLT - MXP
1 stop14h 10mUnited Airlines
Deal found 8/11$643
This Mytrip deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/308:00 amMXP - CLT
3 stops32h 19mMultiple Airlines
Mon 11/107:31 pmCLT - MXP
2 stops22h 04mMultiple Airlines
Deal found 8/11$645
This lol.travel deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/282:40 pmVCE - CLT
2 stops25h 12mUnited Airlines
Mon 9/17:00 amCLT - VCE
2 stops25h 00mUnited Airlines
Deal found 8/11$647

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2025.
Use the filters below to find and compare flights from Italy to South Carolina that are best for you.

Fly from

Italy

Fly to

South Carolina

Route

Depart

Return

Price

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Thu 9/4

7:15 am-1:44 pm

2 stops36h 29m

Charlotte Douglas

Thu 9/11

5:45 am-2:30 pm

1 stop26h 45m

$564

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 10/1

7:05 pm-11:36 pm

1 stop34h 31m

Charlotte Douglas

Sun 10/12

5:45 am-2:30 pm

1 stop26h 45m

$577

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Thu 9/11

5:55 am-11:36 pm

2 stops23h 41m

Charlotte Douglas

Mon 9/15

9:10 am-7:15 pm

2 stops28h 05m

$585

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Thu 10/23

8:20 pm-11:29 pm

2 stops33h 09m

Charlotte Douglas

Mon 10/27

5:45 am-11:05 am

2 stops24h 20m

$585

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 9/3

11:30 am-11:20 pm

2 stops17h 50m

Charlotte Douglas

Wed 9/10

9:10 am-9:15 am

2 stops18h 05m

$590

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Tue 9/9

5:50 am-11:36 pm

2 stops23h 46m

Charlotte Douglas

Tue 9/16

9:10 am-6:40 pm

2 stops27h 30m

$597

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Mon 10/13

7:05 pm-1:58 pm

1 stop24h 53m

Charlotte Douglas

Sun 10/19

5:45 am-2:30 pm

1 stop26h 45m

$610

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Thu 9/25

12:15 pm-11:36 pm

2 stops17h 21m

Charlotte Douglas

Thu 10/2

9:10 am-10:00 am

2 stops18h 50m

$612

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Thu 9/11

9:10 am-11:59 pm

2 stops20h 49m

Charlotte Douglas

Mon 9/15

11:20 am-7:30 am

1 stop14h 10m

$643

VeniceCharlotte

VCE - CLT

VCECLT

Venice Marco Polo

Thu 9/25

6:00 am-11:59 pm

2 stops23h 59m

Charlotte Douglas

Thu 10/2

6:01 pm-1:40 pm

2 stops13h 39m

$647

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/11

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Italy to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to South Carolina

What is the cheapest time of day to fly from IT to SC?

Find hourly flight availability from Italy to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 13, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Italy to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 13, 2025.
Read reviews from past customers who have flown United Airlines and Lufthansa from Italy to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.7

Crew

8.1

Overall

7.4

Comfort

7.3

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.

Boarding

7.7

Crew

8.1

Overall

7.4

Comfort

7.3

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.

Boarding

7.7

Crew

8.1

Overall

7.4

Comfort

7.3

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.

Related info for your journey

Find useful and relevant information for your journey from Italy to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • Can I find deals for flights from Italy to South Carolina that include hotel bookings?

    Yes. In addition to deals on Italy to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to South Carolina.

  • Can I find deals for business class flights from Italy to South Carolina?

    Yes. Cheapflights offers flight deals from Italy to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Italy to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Italy to South Carolina (average of $217). Flying from Italy to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Italy to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Italy to South Carolina

Discover the top airline that operate flights from Italy to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$634Average$690FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.