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$346+ Cheap flights from St. Louis (STL) to Sicily

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CTA
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from St. Louis to Sicily

Keep the following information in mind while searching for St. Louis to Sicily flight deals. Data was last updated September 16, 2025.

Round-trip from

$667
(Trip.com)

One-way from

$346
(Kiwi.com)

Popular in

April

Cheapest in

September

Average price

$852
From Lambert-St Louis to Sicily
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One-way flight from Lambert-St Louis to Sicily
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Highest demand for flights based on searches. 38% potential increase in price ($980 potential increase over avg. RT price).
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Cheapest flight prices on average. 36% potential price decrease ($418 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from St. Louis to Sicily

Cheapest flights from St. Louis to Sicily
Explore the most affordable flight options available from St. Louis to Sicily. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Trip.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3110:30 amSTL - CTA
2 stops20h 50mKLM
Fri 11/73:25 pmCTA - STL
2 stops32h 07mKLM
Deal found 9/16$667
This Orbitz deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/104:25 pmSTL - CTA
2 stops21h 00mBritish Airways
Sun 10/199:50 pmCTA - STL
2 stops27h 32mBritish Airways
Deal found 9/14$907
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/314:50 pmSTL - CTA
1 stop12h 25mMultiple Airlines
Fri 11/76:55 pmCTA - STL
2 stops51h 34mMultiple Airlines
Deal found 9/16$975
This Gurufare deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:30 pmSTL - CTA
1 stop17h 25mLufthansa
Sun 10/196:00 amCTA - STL
2 stops16h 44mLufthansa
Deal found 9/14$1,328
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:30 pmSTL - CTA
2 stops23h 30mMultiple Airlines
Sun 10/198:35 pmCTA - STL
3 stops30h 03mMultiple Airlines
Deal found 9/14$1,635

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from St. Louis to Sicily that are best for you.

Fly from

St. Louis

Fly to

Sicily

Route

Depart

Return

Price

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Fri 10/31

10:30 am-1:20 pm

2 stops20h 50m

Catania Fontanarossa

Fri 11/7

3:25 pm-4:32 pm

2 stops32h 07m

$667

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Fri 10/10

4:25 pm-8:25 pm

2 stops21h 00m

Catania Fontanarossa

Sun 10/19

9:50 pm-6:22 pm

2 stops27h 32m

$907

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Fri 10/31

4:50 pm-11:15 am

1 stop12h 25m

Catania Fontanarossa

Fri 11/7

6:55 pm-3:29 pm

2 stops51h 34m

$975

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Fri 10/10

3:30 pm-3:55 pm

1 stop17h 25m

Catania Fontanarossa

Sun 10/19

6:00 am-3:44 pm

2 stops16h 44m

$1,328

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Fri 10/10

3:30 pm-10:00 pm

2 stops23h 30m

Catania Fontanarossa

Sun 10/19

8:35 pm-7:38 pm

3 stops30h 03m

$1,635

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Tue 11/11

7:45 pm-9:35 am

3 stops54h 50m

$346

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from St. Louis to Sicily

Have a flexible travel schedule? Discover the best time to fly to Sicily from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Sicily

What is the cheapest time of day to fly from STL to SI?

Find hourly flight availability from St. Louis to Sicily. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from St. Louis to Sicily, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Sicily

Get insights into the airlines that provide service to Sicily. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sicily. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from St. Louis to Sicily, such as Delta and Lufthansa. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Lufthansa
6.8
Okay
7,407 reviews
Delta
8.0
Very good
7,957 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Sicily. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Sicily?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly out of when you book flights from St. Louis to Sicily.

  • How long is the flight from St. Louis to Sicily?

    KLM and British Airways can get you from St. Louis to Sicily in just under 20h 50m. Your travel time can differ by up to 10m. St. Louis and Sicily are separated by a distance of 5353 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from St. Louis to Sicily that include hotel bookings?

    Yes. In addition to deals on St. Louis to Sicily flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Sicily?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Sicily.

  • Can I find deals for business class flights from St. Louis to Sicily?

    Yes. Cheapflights offers flight deals from St. Louis to Sicily by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Sicily?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Sicily (average of $667). Flying from St. Louis to Sicily in June is currently the most expensive (average of $1,315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Sicily

See prices for flight routes from nearby airports that may be better suited for you.
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St. Louis to Olbia flights
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Cape Girardeau to Leonardo da Vinci/Fiumicino flights
St. Louis to Cagliari flights

Top 2 airlines flying from St. Louis to Sicily

Discover the top 2 airlines that operate flights from St. Louis to Sicily. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$803Average$1,293FlexibilityNo cancel feeOn-time76%
DeltaCheapest$1,166Average$1,331FlexibilityNo cancel feeOn-timeN/A

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