$491+ Cheap flights from St. Louis (STL) to Sicily
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CTA
May 9 — May 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from St. Louis to SicilyExplore the most affordable flight options available from St. Louis to Sicily. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from St. Louis to Sicily. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This KLM deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/94:12 pm
STL
- CTA
1 stop32h 43m
KLM
Sat 8/2210:15 am
CTA
- STL
2 stops20h 22m
KLM
Deal found 4/5![KLM logo]()
$821
This KLM deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1212:28 pm
STL
- CTA
2 stops19h 12m
KLM
Tue 4/219:55 am
CTA
- STL
2 stops20h 41m
KLM
Deal found 4/6![KLM logo]()
$860
This Cheapflightsfares deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:18 pm
STL
- CTA
2 stops27h 12m
Lufthansa
Fri 9/116:00 am
CTA
- STL
2 stops16h 38m
Lufthansa
Deal found 4/6![Lufthansa logo]()
$897
This Gotogate deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:54 am
STL
- CTA
2 stops26h 01m
British Airways
Tue 4/217:55 pm
CTA
- STL
1 stop30h 35m
British Airways
Deal found 4/6![British Airways logo]()
$906
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:30 pm
STL
- CTA
2 stops29h 35m
United Airlines
Fri 9/1110:40 am
CTA
- STL
1 stop15h 01m
United Airlines
Deal found 4/5![United Airlines logo]()
$938
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
STL
- CTA
2 stops18h 55m
Delta
Wed 5/2010:00 am
CTA
- STL
2 stops18h 09m
Delta
Deal found 4/5![Delta logo]()
$946
This FlightHub deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:32 pm
STL
- CTA
2 stops32h 33m
Air Canada
Fri 9/1110:40 am
CTA
- STL
1 stop15h 01m
Air Canada
Deal found 4/6![Air Canada logo]()
$949
This KLM deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:25 pm
STL
- CTA
1 stop32h 30m
Multiple Airlines
Wed 5/2010:00 am
CTA
- STL
2 stops20h 21m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$953
This Gotogate deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:55 am
STL
- CTA
2 stops27h 55m
Air Canada
Wed 9/3010:40 am
CTA
- STL
2 stops34h 20m
Air Canada
Deal found 4/5![Air Canada logo]()
$955
Best flights from St. Louis to SicilyDiscover carefully curated flight deals from St. Louis to Sicily that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from St. Louis to Sicily that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This KLM deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/94:12 pm
STL
- CTA
1 stop32h 43m
KLM
Sat 8/2210:15 am
CTA
- STL
2 stops20h 22m
KLM
Deal found 4/5![KLM logo]()
$821
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:30 pm
STL
- CTA
2 stops29h 35m
United Airlines
Fri 9/1110:40 am
CTA
- STL
1 stop15h 01m
United Airlines
Deal found 4/4![United Airlines logo]()
$938
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
STL
- CTA
2 stops18h 55m
Delta
Wed 5/2010:00 am
CTA
- STL
2 stops18h 09m
Delta
Deal found 4/5![Delta logo]()
$946
This KLM deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:25 pm
STL
- CTA
1 stop32h 30m
Multiple Airlines
Wed 5/2010:00 am
CTA
- STL
2 stops20h 21m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$953
This Orbitz deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:10 pm
STL
- CTA
1 stop13h 55m
Air Canada
Thu 10/89:00 am
CTA
- STL
2 stops36h 00m
Air Canada
Deal found 4/8![Air Canada logo]()
$994
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:45 pm
STL
- CTA
2 stops17h 55m
Delta
Fri 9/49:55 am
CTA
- STL
2 stops20h 42m
Delta
Deal found 4/7![Delta logo]()
$1,000
Last-minute flights from St. Louis to SicilyDiscover last-minute flight deals from St. Louis to Sicily. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Sicily. Data last updated April 9, 2026 and is based on user searches.
This BusinessClass deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:45 am
STL
- CTA
2 stops27h 40m
Turkish Airlines
Sat 4/119:25 am
CTA
- STL
2 stops42h 48m
Turkish Airlines
Deal found 4/5![Turkish Airlines logo]()
$1,186
This KLM deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1212:28 pm
STL
- CTA
2 stops19h 12m
KLM
Tue 4/219:55 am
CTA
- STL
2 stops20h 41m
KLM
Deal found 4/6![KLM logo]()
$860
This Gotogate deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:54 am
STL
- CTA
2 stops26h 01m
British Airways
Tue 4/217:55 pm
CTA
- STL
1 stop30h 35m
British Airways
Deal found 4/6![British Airways logo]()
$906
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
STL
- CTA
2 stops18h 55m
Delta
Wed 5/2010:00 am
CTA
- STL
2 stops18h 09m
Delta
Deal found 4/5![Delta logo]()
$946
This KLM deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:25 pm
STL
- CTA
1 stop32h 30m
Multiple Airlines
Wed 5/2010:00 am
CTA
- STL
2 stops20h 21m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$953
This KLM deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:25 pm
STL
- CTA
1 stop32h 30m
KLM
Wed 5/2010:00 am
CTA
- STL
2 stops20h 59m
KLM
Deal found 4/7![KLM logo]()
$1,003
This Booking.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:53 pm
STL
- CTA
2 stops34h 22m
British Airways
Mon 6/16:45 pm
CTA
- STL
2 stops55h 36m
British Airways
Deal found 4/6![British Airways logo]()
$1,245
One-way flights from St. Louis to SicilySearch for one-way flight options from St. Louis to Sicily. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from St. Louis to Sicily. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Expedia deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:07 pm
STL
- CTA
2 stops39h 58m
Iberia
Deal found 4/8![Iberia logo]()
$491
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/264:29 pm
STL
- CTA
3 stops49h 26m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$558
This Mytrip deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:40 am
STL
- CTA
3 stops32h 25m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$573
This KLM deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/264:13 pm
STL
- CTA
1 stop32h 42m
KLM
Deal found 4/8![KLM logo]()
$721
This Iberia deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/149:40 pm
STL
- CTA
2 stops30h 40m
Iberia
Deal found 4/6![Iberia logo]()
$880
This Cheapflightsfares deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/143:30 pm
STL
- CTA
1 stop17h 00m
Lufthansa
Deal found 4/6![Lufthansa logo]()
$1,091
This KLM deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/144:13 pm
STL
- CTA
1 stop32h 42m
KLM
Deal found 4/5![KLM logo]()
$1,168
This BusinessClass deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:30 pm
STL
- CTA
1 stop17h 10m
Lufthansa
Deal found 4/8![Lufthansa logo]()
$1,262
Find flight deals from St. Louis to Sicily
Keep the following information in mind while searching for St. Louis to Sicily flight deals. Data was last updated April 9, 2026.
Round-trip from | $821 (KLM) |
|---|---|
One-way from | $491 (Expedia) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from St. Louis to Sicily that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCatania
STL - CTA
STLCTA
Lambert-St Louis
Sun 8/9
4:12 pm-7:55 am
1 stop32h 43m
Catania Fontanarossa
Sat 8/22
10:15 am-11:37 pm
2 stops20h 22m
$821
St. LouisCatania
STL - CTA
STLCTA
Lambert-St Louis
Mon 8/31
8:30 pm-9:05 am
2 stops29h 35m
Catania Fontanarossa
Fri 9/11
10:40 am-6:41 pm
1 stop15h 01m
$938
Quickest round-trip
St. LouisCatania
STL - CTA
STLCTA
Lambert-St Louis
Tue 5/12
6:00 am-7:55 am
2 stops18h 55m
Catania Fontanarossa
Wed 5/20
10:00 am-9:09 pm
2 stops18h 09m
$946
St. LouisCatania
STL - CTA
STLCTA
Lambert-St Louis
Tue 5/12
4:25 pm-7:55 am
1 stop32h 30m
Catania Fontanarossa
Wed 5/20
10:00 am-11:21 pm
2 stops20h 21m
$953
St. LouisCatania
STL - CTA
STLCTA
Lambert-St Louis
Tue 9/29
12:10 pm-9:05 am
1 stop13h 55m
Catania Fontanarossa
Thu 10/8
9:00 am-2:00 pm
2 stops36h 00m
$994
St. LouisCatania
STL - CTA
STLCTA
Lambert-St Louis
Wed 8/26
5:45 pm-6:40 pm
2 stops17h 55m
Catania Fontanarossa
Fri 9/4
9:55 am-11:37 pm
2 stops20h 42m
$1,000
Cheapest one-way
St. LouisCatania
STL - CTA
STLCTA
Lambert-St Louis
Sat 9/26
8:07 pm-7:05 pm
2 stops39h 58m
$491
St. LouisCatania
STL - CTA
STLCTA
Lambert-St Louis
Sat 9/26
4:13 pm-7:55 am
1 stop32h 42m
$721
St. LouisCatania
STL - CTA
STLCTA
Lambert-St Louis
Sun 6/14
9:40 pm-11:20 am
2 stops30h 40m
$880
St. LouisCatania
STL - CTA
STLCTA
Lambert-St Louis
Sun 6/14
2:33 pm-7:05 pm
2 stops21h 32m
$882
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Sicily
Have a flexible travel schedule? Discover the best time to fly to Sicily from St. Louis with our price prediction graph.
STL-CTA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Sicily
STL-ITSI
STL-CTA
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Sicily
Get insights into the airlines that provide service to Sicily. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sicily. Reviews last updated April 9, 2026.
Read through reviews of airlines operating flights from St. Louis to Sicily, such as Delta,Air Canada, andLufthansa. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Boarding
8.1
Overall
7.9
Entertainment
7.8
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Overall
7.9
Entertainment
7.8
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Overall
7.9
Entertainment
7.8
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Overall
7.9
Entertainment
7.8
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Sicily. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to Sicily
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Complete your trip
Complete your trip to Sicily by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Sicily by cabin class
Find flights from St. Louis to Sicily, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Sicily flights
Browse other St. Louis and Sicily flight options. Last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from St. Louis to Sicily
Discover the top 3 airlines that operate flights from St. Louis to Sicily. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$518 | Average$1,171 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$554 | Average$1,034 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$1,033 | Average$1,331 | FlexibilityNo cancel fee | On-timeN/A |