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$336+ Cheap flights from Mississippi to Sicily

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CTA
ene. 16 — ene. 231
vie. 1/16
vie. 1/23
1 adult, Economy
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Cheap flight deals from Mississippi to Sicily

Best flights from Mississippi to Sicily
Discover carefully curated flight deals from Mississippi to Sicily that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/2712:00 pmMEM - PMO
2 stops16h 30mLufthansa
dom. 5/311:55 amPMO - MEM
2 stops17h 04mLufthansa
Deal found 12/15$817
This KLM deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/302:40 pmGPT - PMO
2 stops16h 00mKLM
vie. 2/612:25 pmPMO - GPT
2 stops40h 28mKLM
Deal found 12/16$1,000
This Air Canada deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/279:40 amMEM - PMO
3 stops18h 50mAir Canada
dom. 5/310:05 amPMO - MEM
3 stops31h 57mAir Canada
Deal found 12/15$1,748
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/277:29 amMEM - PMO
3 stops20h 51mMultiple Airlines
dom. 5/31:15 pmPMO - MEM
2 stops36h 34mMultiple Airlines
Deal found 12/15$1,944

Find flight deals from Mississippi to Sicily

Keep the following information in mind while searching for Mississippi to Sicily flight deals. Data was last updated diciembre 17, 2025.

Round-trip from

$817
(Cheapflightsfares)

One-way from

$336
(Kiwi.com)
From Mississippi to Sicily
Search Deals
One-way flight from Mississippi to Sicily
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 17, 2025.
Use the filters below to find and compare flights from Mississippi to Sicily that are best for you.

Fly from

Mississippi

Fly to

Sicily

Route

Depart

Return

Price

MemphisPalermo

MEM - PMO

MEMPMO

Memphis

lun. 4/27

12:00 pm-11:30 am

2 stops16h 30m

Palermo Punta Raisi

dom. 5/3

11:55 am-9:59 pm

2 stops17h 04m

$817

GulfportPalermo

GPT - PMO

GPTPMO

Gulfport Biloxi Regional

vie. 1/30

2:40 pm-1:40 pm

2 stops16h 00m

Palermo Punta Raisi

vie. 2/6

12:25 pm-9:53 pm

2 stops40h 28m

$1,000

MemphisPalermo

MEM - PMO

MEMPMO

Memphis

lun. 4/27

9:40 am-11:30 am

3 stops18h 50m

Palermo Punta Raisi

dom. 5/3

10:05 am-11:02 am

3 stops31h 57m

$1,748

MemphisPalermo

MEM - PMO

MEMPMO

Memphis

lun. 4/27

7:29 am-11:20 am

3 stops20h 51m

Palermo Punta Raisi

dom. 5/3

1:15 pm-6:49 pm

2 stops36h 34m

$1,944

GulfportPalermo

GPT - PMO

GPTPMO

Gulfport Biloxi Regional

dom. 3/15

7:20 pm-10:35 pm

3 stops45h 15m

$336

MemphisPalermo

MEM - PMO

MEMPMO

Memphis

jue. 5/21

2:27 pm-7:05 pm

2 stops21h 38m

$677

MemphisPalermo

MEM - PMO

MEMPMO

Memphis

jue. 5/21

11:14 am-12:20 am

3 stops30h 06m

$720

MemphisPalermo

MEM - PMO

MEMPMO

Memphis

jue. 5/21

6:05 am-6:00 pm

2 stops28h 55m

$760

GulfportPalermo

GPT - PMO

GPTPMO

Gulfport Biloxi Regional

dom. 3/15

10:04 am-11:40 am

2 stops19h 36m

$852

MemphisPalermo

MEM - PMO

MEMPMO

Memphis

jue. 5/21

3:56 pm-7:15 am

1 stop32h 19m

$1,550

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Best time to book a flight from Mississippi to Sicily

Have a flexible travel schedule? Discover the best time to fly to Sicily from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Sicily
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Sicily. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Sicily?

    Airlines like Lufthansa, KLM, and Air Canada fly from Mississippi to Sicily in about 16h. The time it takes to get you to your destination can typically vary by up to 2h 50m. There are 5538 mi between Mississippi and Sicily. This flight may include one or multiple stops.

  • Can I find deals for flights from Mississippi to Sicily that include hotel bookings?

    Yes. In addition to deals on Mississippi to Sicily flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Sicily?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Sicily.

  • Can I find deals for business class flights from Mississippi to Sicily?

    Yes. Cheapflights offers flight deals from Mississippi to Sicily by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Mississippi to Sicily

See prices for flight routes from nearby airports that may be better suited for you.
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