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Sicily

$221+ Cheap flights from Irvine, CA to Sicily

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — CTA
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Irvine to Sicily

Keep the following information in mind while searching for Irvine to Sicily flight deals. Data was last updated September 16, 2025.

Round-trip from

$450
(KLM)

One-way from

$221
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$789
From Irvine to Sicily
Search Deals
One-way flight from Irvine to Sicily
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Highest demand for flights based on searches. 14% potential increase in price ($162 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($70 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Irvine to Sicily

Cheapest flights from Irvine to Sicily
Explore the most affordable flight options available from Irvine to Sicily. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This KLM deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/41:45 pmLAX - CTA
1 stop34h 35mKLM
Thu 11/1310:10 amCTA - LAX
1 stop34h 35mKLM
Deal found 9/15$450
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/195:30 pmLAX - CTA
1 stop15h 15mMultiple Airlines
Mon 11/38:40 pmCTA - LAX
1 stop28h 55mMultiple Airlines
Deal found 9/16$480
This AirNGo deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:30 pmLAX - CTA
3 stops42h 20mAir Canada
Mon 12/18:40 pmCTA - LAX
2 stops48h 04mAir Canada
Deal found 9/14$486
This Flighttix deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:30 pmLAX - CTA
3 stops42h 20mMultiple Airlines
Mon 12/18:40 pmCTA - LAX
1 stop28h 55mMultiple Airlines
Deal found 9/14$499
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:15 pmLAX - CTA
1 stop21h 10mMultiple Airlines
Fri 11/77:00 amCTA - LAX
1 stop17h 15mMultiple Airlines
Deal found 9/16$509
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:10 pmLAX - CTA
1 stop27h 55mMultiple Airlines
Wed 11/1912:25 pmCTA - LAX
1 stop33h 40mMultiple Airlines
Deal found 9/15$520
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:15 pmLAX - PMO
1 stop21h 35mMultiple Airlines
Fri 11/76:00 amPMO - LAX
1 stop18h 15mMultiple Airlines
Deal found 9/16$534
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:15 pmLAX - CTA
1 stop21h 10mMultiple Airlines
Tue 11/116:00 amCTA - LAX
1 stop19h 50mMultiple Airlines
Deal found 9/16$536
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:00 pmLAX - CTA
1 stop16h 00mMultiple Airlines
Sun 11/168:20 pmCTA - LAX
1 stop25h 10mMultiple Airlines
Deal found 9/16$539
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:30 pmLAX - PMO
1 stop18h 10mMultiple Airlines
Wed 11/57:00 pmPMO - LAX
1 stop24h 55mMultiple Airlines
Deal found 9/15$549
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:30 pmLAX - PMO
1 stop16h 05mMultiple Airlines
Fri 11/76:00 amPMO - LAX
1 stop18h 15mMultiple Airlines
Deal found 9/15$572
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:30 pmLAX - PMO
1 stop15h 00mMultiple Airlines
Thu 11/67:00 pmPMO - LAX
1 stop29h 15mMultiple Airlines
Deal found 9/15$579

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Irvine to Sicily that are best for you.

Fly from

Irvine

Fly to

Sicily

Route

Depart

Return

Price

Los AngelesCatania

LAX - CTA

LAXCTA

Los Angeles

Tue 11/4

1:45 pm-9:20 am

1 stop34h 35m

Catania Fontanarossa

Thu 11/13

10:10 am-11:45 am

1 stop34h 35m

$450

Los AngelesCatania

LAX - CTA

LAXCTA

Los Angeles

Wed 11/12

7:10 pm-8:05 am

1 stop27h 55m

Catania Fontanarossa

Wed 11/19

12:25 pm-1:05 pm

1 stop33h 40m

$520

Los AngelesCatania

LAX - CTA

LAXCTA

Los Angeles

Mon 11/10

12:30 pm-8:40 pm

2 stops47h 10m

Catania Fontanarossa

Sun 11/16

8:40 pm-4:35 pm

1 stop28h 55m

$560

Los AngelesCatania

LAX - CTA

LAXCTA

Los Angeles

Sun 10/19

8:05 am-2:40 pm

3 stops21h 35m

Catania Fontanarossa

Mon 11/3

11:10 pm-4:35 pm

2 stops26h 25m

$567

Los AngelesLamezia Terme

LAX - SUF

LAXSUF

Los Angeles

Fri 11/7

3:20 pm-10:30 am

1 stop34h 10m

Lamezia Terme Intl

Thu 11/13

7:15 pm-1:30 pm

1 stop27h 15m

$586

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Mon 10/13

5:05 pm-11:45 am

1 stop33h 40m

Palermo Punta Raisi

Mon 10/20

7:55 pm-5:17 pm

2 stops30h 22m

$617

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Mon 9/29

7:55 pm-6:15 pm

1 stop37h 20m

Palermo Punta Raisi

Thu 10/9

9:20 am-11:45 am

1 stop35h 25m

$625

Los AngelesCatania

LAX - CTA

LAXCTA

Los Angeles

Sat 9/27

10:00 pm-5:40 pm

2 stops34h 40m

Catania Fontanarossa

Mon 10/6

6:45 pm-10:59 pm

2 stops37h 14m

$630

Los AngelesCatania

LAX - CTA

LAXCTA

Los Angeles

Wed 10/29

2:18 pm-4:45 pm

2 stops18h 27m

Catania Fontanarossa

Wed 11/5

12:25 pm-1:05 pm

1 stop33h 40m

$639

Los AngelesReggio Calabria

LAX - REG

LAXREG

Los Angeles

Wed 2/25

3:20 pm-10:55 pm

1 stop22h 35m

Reggio Calabria Tito Menniti

Sun 3/1

6:10 am-1:30 pm

1 stop16h 20m

$642

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 53 results
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Best time to book a flight from Irvine to Sicily

Have a flexible travel schedule? Discover the best time to fly to Sicily from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Sicily

What is the cheapest month to book a flight from Irvine to Sicily?

Currently, January is the cheapest month in which you can book a flight from Irvine to Sicily (average of $667). Flying from Irvine to Sicily in June is currently the most expensive (average of $1,315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to SI?

Find hourly flight availability from Irvine to Sicily. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Sicily as you normally would.

Reviews of airlines servicing Sicily

Get insights into the airlines that provide service to Sicily. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sicily. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Irvine to Sicily, such as Delta, SWISS, and Turkish Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
SWISS
7.6
Good
1,737 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Turkish Airlines
7.3
Good
3,968 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Lufthansa
6.8
Okay
7,407 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
ITA Airways
6.7
Okay
1,036 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Sicily. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Irvine to Sicily?

    For as low as $617, KLM can have you in Sicily from Irvine in 33h 40m. Irvine and Sicily are separated by a distance of 6559 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Irvine to Sicily?

    The most popular flight routes from Irvine to Sicily are Los Angeles - Catania Fontanarossa, Los Angeles - Palermo Punta Raisi and Los Angeles - Reggio Calabria Tito Menniti.

  • Can I find deals for flights from Irvine to Sicily that include hotel bookings?

    Yes. In addition to deals on Irvine to Sicily flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Sicily?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Sicily.

  • Can I find deals for business class flights from Irvine to Sicily?

    Yes. Cheapflights offers flight deals from Irvine to Sicily by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Sicily?

    Currently, January is the cheapest month in which you can book a flight from Irvine to Sicily (average of $667). Flying from Irvine to Sicily in June is currently the most expensive (average of $1,315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Irvine to Sicily

Discover the top 6 airlines that operate flights from Irvine to Sicily. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
SWISSCheapest$487Average$834FlexibilityNo cancel feeOn-time79%
LufthansaCheapest$604Average$883FlexibilityNo cancel feeOn-time76%
DeltaCheapest$624Average$977FlexibilityNo cancel feeOn-timeN/A
ITA AirwaysCheapest$632Average$995FlexibilityNo cancel feeOn-time81%
British AirwaysCheapest$640Average$871FlexibilityNo cancel feeOn-time70%
Turkish AirlinesCheapest$717Average$843FlexibilityNo cancel feeOn-time77%

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