$415+ Cheap flights from Knoxville (TYS) to Sedona, AZ
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PHX
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Sedona with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Sedona
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to SedonaExplore the most affordable flight options available from Knoxville to Sedona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Knoxville to Sedona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:30 am -
1 stop9h 27m
Sat 12/51:22 pm -
1 stop8h 10m
Deal found 9/2![American Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:15 am -
2 stops11h 45m
Tue 9/2210:40 am -
2 stops9h 10m
Deal found 9/3![American Airlines logo]()
$593
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:50 am -
1 stop8h 00m
Tue 11/31:22 pm -
1 stop6h 17m
Deal found 9/3![American Airlines logo]()
$806
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:30 am -
2 stops8h 40m
Mon 11/21:22 pm -
1 stop6h 17m
Deal found 9/3![American Airlines logo]()
$830
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:50 pm -
1 stop20h 03m
Thu 9/1012:37 pm -
1 stop7h 45m
Deal found 9/4![American Airlines logo]()
$1,257
Best flights from Knoxville to SedonaDiscover carefully curated flight deals from Knoxville to Sedona that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Knoxville to Sedona that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:30 am -
1 stop9h 27m
Sat 12/51:22 pm -
1 stop8h 10m
Deal found 9/2![American Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:15 am -
2 stops11h 45m
Tue 9/2210:40 am -
2 stops9h 10m
Deal found 9/3![American Airlines logo]()
$593
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/63:00 pm -
2 stops10h 58m
Sat 3/139:08 pm -
2 stops8h 34m
Deal found 9/4![American Airlines logo]()
$804
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:50 am -
1 stop8h 00m
Tue 11/311:16 am -
2 stops8h 23m
Deal found 9/3![American Airlines logo]()
$816
Last-minute flights from Knoxville to SedonaDiscover last-minute flight deals from Knoxville to Sedona. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Sedona. Data last updated September 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:50 pm -
1 stop20h 03m
Thu 9/1012:37 pm -
1 stop7h 45m
Deal found 9/4![American Airlines logo]()
$1,257
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:15 am -
2 stops11h 45m
Tue 9/2210:40 am -
2 stops9h 10m
Deal found 9/3![American Airlines logo]()
$593
One-way flights from Knoxville to SedonaSearch for one-way flight options from Knoxville to Sedona. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Knoxville to Sedona. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop9h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$415
Find flight deals from Knoxville to Sedona
Keep the following information in mind while searching for Knoxville to Sedona flight deals. Data was last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $592 (American Airlines) |
One-way from | $415 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Sedona that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Knoxville to Sedona that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Mon 10/19
6:00 am-12:05 pm
1 stop9h 05m
Flagstaff Pulliam
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$415
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Sat 11/28
5:30 am-12:57 pm
1 stop9h 27m
Flagstaff Pulliam
Sat 12/5
1:22 pm-11:32 pm
1 stop8h 10m
$592
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Fri 9/18
6:15 am-3:00 pm
2 stops11h 45m
Flagstaff Pulliam
Tue 9/22
10:40 am-10:50 pm
2 stops9h 10m
$593
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Sat 3/6
3:00 pm-11:58 pm
2 stops10h 58m
Flagstaff Pulliam
Sat 3/13
9:08 pm-7:42 am
2 stops8h 34m
$804
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Mon 11/2
6:50 am-12:50 pm
1 stop8h 00m
Flagstaff Pulliam
Tue 11/3
11:16 am-9:39 pm
2 stops8h 23m
$816
Sorted by cheapest first
Best time to book a flight from Knoxville to Sedona
Have a flexible travel schedule? Discover the best time to fly to Sedona from Knoxville with our price prediction graph.
TYS-FLG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Sedona
TYS-SE9
TYS-FLG
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Sedona
Get insights into the airlines that provide service to Sedona. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sedona. Reviews last updated September 7, 2026.
Read reviews from past customers who have flown American Airlines from Knoxville to Sedona. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Overall
7.1
Boarding
7.5
Comfort
7.2
Entertainment
6.8
Food
6.4
Reviews
1 / 20
6.0
GoodKristin,Jul 2026
DCA - PHX
Crew
7.9
Overall
7.1
Boarding
7.5
Comfort
7.2
Entertainment
6.8
Food
6.4
Reviews
1 / 20
6.0
GoodKristin,Jul 2026
DCA - PHX
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Sedona. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Sedona
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Complete your trip
Complete your trip to Sedona by adding a car rental and/or hotel reservation to your travel itinerary.
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Knoxville and Sedona flights
Browse other Knoxville and Sedona flight options. Last updated on September 7, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Popular flight searches
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Knoxville to Sedona flights
Consider these flights traveling from Knoxville to Sedona.
Top 6 airlines flying from Knoxville to Sedona
Discover the top 6 airlines that operate flights from Knoxville to Sedona. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$124 | Average$284 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$125 | Average$324 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$130 | Average$396 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$557 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$439 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$284 | Average$483 | FlexibilityNo cancel fee | On-time71% |