$466+ Cheap flights from Knoxville (TYS) to Sedona, AZ
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PHX
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Sedona with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Sedona
Cheapest
Best
Last-minute
Cheapest flights from Knoxville to SedonaExplore the most affordable flight options available from Knoxville to Sedona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Knoxville to Sedona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop9h 05m
Sat 10/317:15 am -
1 stop6h 21m
Deal found 9/11![American Airlines logo]()
$466
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:50 am -
1 stop8h 02m
Sat 11/213:00 pm -
1 stop6h 32m
Deal found 9/13![American Airlines logo]()
$486
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop9h 05m
Sat 10/1710:34 am -
2 stops9h 44m
Deal found 9/12![American Airlines logo]()
$774
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/293:24 pm -
2 stops10h 20m
Sun 1/38:50 pm -
2 stops10h 01m
Deal found 9/13![American Airlines logo]()
$819
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop9h 05m
Fri 10/1612:45 pm -
1 stop7h 33m
Deal found 9/12![American Airlines logo]()
$840
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
1 stop9h 05m
Sat 10/1710:34 am -
2 stops9h 44m
Deal found 9/12![American Airlines logo]()
$850
Best flights from Knoxville to SedonaDiscover carefully curated flight deals from Knoxville to Sedona that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Knoxville to Sedona that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop9h 05m
Sat 10/317:15 am -
1 stop6h 21m
Deal found 9/11![American Airlines logo]()
$466
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:50 am -
1 stop8h 02m
Sat 11/213:00 pm -
1 stop6h 32m
Deal found 9/13![American Airlines logo]()
$486
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/293:24 pm -
2 stops10h 20m
Sun 1/38:50 pm -
2 stops10h 01m
Deal found 9/13![American Airlines logo]()
$819
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop9h 05m
Fri 10/1612:45 pm -
1 stop7h 33m
Deal found 9/12![American Airlines logo]()
$840
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop9h 05m
Sat 10/1712:45 pm -
1 stop7h 33m
Deal found 9/12![American Airlines logo]()
$877
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
1 stop9h 05m
Sat 10/1712:45 pm -
1 stop7h 33m
Deal found 9/12![American Airlines logo]()
$953
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:41 pm -
2 stops8h 42m
Sun 10/116:20 pm -
2 stops11h 12m
Deal found 9/10![American Airlines logo]()
$978
Last-minute flights from Knoxville to SedonaDiscover last-minute flight deals from Knoxville to Sedona. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Sedona. Data last updated September 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
1 stop9h 05m
Sat 10/1710:34 am -
2 stops9h 44m
Deal found 9/12![American Airlines logo]()
$850
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
1 stop9h 05m
Fri 10/1612:45 pm -
1 stop7h 33m
Deal found 9/12![American Airlines logo]()
$928
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop9h 05m
Sat 10/1710:34 am -
2 stops9h 44m
Deal found 9/12![American Airlines logo]()
$774
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop9h 05m
Fri 10/1612:45 pm -
1 stop7h 33m
Deal found 9/12![American Airlines logo]()
$840
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop9h 05m
Sat 10/317:15 am -
1 stop6h 21m
Deal found 9/11![American Airlines logo]()
$466
Find flight deals from Knoxville to Sedona
Keep the following information in mind while searching for Knoxville to Sedona flight deals. Data was last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $466 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Sedona that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Knoxville to Sedona that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Tue 10/27
6:00 am-12:05 pm
1 stop9h 05m
Flagstaff Pulliam
Sat 10/31
7:15 am-4:36 pm
1 stop6h 21m
$466
Quickest round-trip
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Wed 11/18
6:50 am-12:52 pm
1 stop8h 02m
Flagstaff Pulliam
Sat 11/21
3:00 pm-11:32 pm
1 stop6h 32m
$486
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Tue 12/29
3:24 pm-11:44 pm
2 stops10h 20m
Flagstaff Pulliam
Sun 1/3
8:50 pm-8:51 am
2 stops10h 01m
$819
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Mon 10/12
6:00 am-12:05 pm
1 stop9h 05m
Flagstaff Pulliam
Fri 10/16
12:45 pm-11:18 pm
1 stop7h 33m
$840
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Mon 10/12
6:00 am-12:05 pm
1 stop9h 05m
Flagstaff Pulliam
Sat 10/17
12:45 pm-11:18 pm
1 stop7h 33m
$877
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Sun 10/11
6:00 am-12:05 pm
1 stop9h 05m
Flagstaff Pulliam
Sat 10/17
12:45 pm-11:18 pm
1 stop7h 33m
$953
KnoxvilleFlagstaff
TYS Knoxville McGhee Tyson - FLG Flagstaff Pulliam
TYSFLG
Knoxville McGhee Tyson
Fri 10/9
3:41 pm-9:23 pm
2 stops8h 42m
Flagstaff Pulliam
Sun 10/11
6:20 pm-8:32 am
2 stops11h 12m
$978
Sorted by cheapest first
Best time to book a flight from Knoxville to Sedona
Have a flexible travel schedule? Discover the best time to fly to Sedona from Knoxville with our price prediction graph.
TYS-FLG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Sedona
TYS-SE9
TYS-FLG
What is the cheapest time of day to fly from TYS to SE9?
Find hourly flight availability from Knoxville to Sedona. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Sedona as you normally would.
Reviews of airlines servicing Sedona
Get insights into the airlines that provide service to Sedona. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sedona. Reviews last updated September 14, 2026.
Read reviews from past customers who have flown American Airlines from Knoxville to Sedona. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Food
6.4
Comfort
7.2
Entertainment
6.8
Boarding
7.4
Overall
7.1
Reviews
1 / 20
6.0
GoodKristin,Jul 2026
DCA - PHX
Crew
7.9
Food
6.4
Comfort
7.2
Entertainment
6.8
Boarding
7.4
Overall
7.1
Reviews
1 / 20
6.0
GoodKristin,Jul 2026
DCA - PHX
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Sedona. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Sedona
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Complete your trip
Complete your trip to Sedona by adding a car rental and/or hotel reservation to your travel itinerary.
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Knoxville and Sedona flights
Browse other Knoxville and Sedona flight options. Last updated on September 14, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Popular flight searches
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Knoxville to Sedona flights
Consider these flights traveling from Knoxville to Sedona.
Top 6 airlines flying from Knoxville to Sedona
Discover the top 6 airlines that operate flights from Knoxville to Sedona. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$125 | Average$324 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$127 | Average$287 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$148 | Average$398 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$557 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$284 | Average$485 | FlexibilityNo cancel fee | On-time71% |