HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santo Domingo

$161+ Cheap flights from Syracuse (SYR) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — SDQ
Apr 8 — Apr 151
Wed 4/8
Wed 4/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Syracuse to Santo Domingo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Syracuse to Santo Domingo

Cheapest flights from Syracuse to Santo Domingo
Explore the most affordable flight options available from Syracuse to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 9, 2026.

This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:11 am
SYR
-
SDQ
1 stop13h 47m
American Airlines
Sat 10/245:20 pm
SDQ
-
SYR
2 stops17h 24m
American Airlines
Deal found 3/5$349
This Billigflug deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:51 am
SYR
-
SDQ
1 stop12h 26m
Multiple Airlines
Sat 4/256:05 am
SDQ
-
SYR
1 stop9h 23m
Multiple Airlines
Deal found 3/4$417
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:30 am
SYR
-
SDQ
1 stop6h 54m
Delta
Sat 10/247:49 pm
SDQ
-
SYR
1 stop14h 46m
Delta
Deal found 3/5$429
This JetBlue deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:00 pm
SYR
-
SDQ
1 stop10h 40m
JetBlue
Thu 5/143:23 pm
SDQ
-
SYR
1 stop8h 36m
JetBlue
Deal found 3/4$434
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:08 am
SYR
-
SDQ
2 stops16h 47m
American Airlines
Wed 7/222:23 pm
SDQ
-
SYR
2 stops9h 57m
American Airlines
Deal found 3/7$435
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:20 pm
SYR
-
SDQ
1 stop17h 25m
American Airlines
Wed 8/197:00 am
SDQ
-
SYR
2 stops17h 15m
American Airlines
Deal found 3/5$441
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:33 pm
SYR
-
SDQ
2 stops20h 37m
United Airlines
Wed 9/301:10 pm
SDQ
-
SYR
2 stops10h 23m
United Airlines
Deal found 3/6$459
This JetBlue deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:10 am
SYR
-
SDQ
1 stop6h 55m
JetBlue
Mon 4/273:30 pm
SDQ
-
SYR
1 stop8h 29m
JetBlue
Deal found 3/6$462
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:01 am
SYR
-
SDQ
2 stops16h 58m
American Airlines
Tue 7/284:26 pm
SDQ
-
SYR
2 stops17h 58m
American Airlines
Deal found 3/4$474
This Faresmojo deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1311:25 am
SYR
-
SDQ
1 stop6h 35m
JetBlue
Wed 7/221:55 pm
SDQ
-
SYR
1 stop10h 02m
JetBlue
Deal found 3/7$486
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:03 pm
SYR
-
SDQ
1 stop19h 26m
Multiple Airlines
Sun 4/262:35 pm
SDQ
-
SYR
1 stop20h 06m
Multiple Airlines
Deal found 3/5$497

Find flight deals from Syracuse to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$349
(American Airlines)

One-way from

$161
(American Airlines)

Popular in

February

Cheapest in

January

Average price

$486
Provider with most accurate pricing for Syracuse Hancock Intl-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Santo Domingo Las Americas flights.
Search Deals
From Syracuse Hancock Intl to Santo Domingo Las Americas
Search Deals
One-way flight from Syracuse Hancock Intl to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($10 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 9, 2026.
Use the filters below to find and compare flights from Syracuse to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracuseSanto Domingo

SYR - SDQ

SYRSDQ

Syracuse Hancock Intl

Sat 4/18

11:51 am-12:17 am

1 stop12h 26m

Santo Domingo Las Americas

Sat 4/25

6:05 am-3:28 pm

1 stop9h 23m

$417

SyracuseSanto Domingo

SYR - SDQ

SYRSDQ

Syracuse Hancock Intl

Mon 5/11

9:00 pm-7:40 am

1 stop10h 40m

Santo Domingo Las Americas

Thu 5/14

3:23 pm-11:59 pm

1 stop8h 36m

$434

SyracuseSanto Domingo

SYR - SDQ

SYRSDQ

Syracuse Hancock Intl

Fri 8/21

8:21 am-6:20 pm

2 stops9h 59m

Santo Domingo Las Americas

Tue 8/25

7:00 am-12:15 am

2 stops17h 15m

$434

SyracuseSanto Domingo

SYR - SDQ

SYRSDQ

Syracuse Hancock Intl

Sat 6/13

6:08 am-10:55 pm

2 stops16h 47m

Santo Domingo Las Americas

Wed 7/22

2:23 pm-12:20 am

2 stops9h 57m

$435

SyracuseSanto Domingo

SYR - SDQ

SYRSDQ

Syracuse Hancock Intl

Sat 7/25

7:20 pm-12:45 pm

1 stop17h 25m

Santo Domingo Las Americas

Wed 8/19

7:00 am-12:15 am

2 stops17h 15m

$441
Quickest round-trip

SyracuseSanto Domingo

SYR - SDQ

SYRSDQ

Syracuse Hancock Intl

Mon 4/20

7:10 am-2:05 pm

1 stop6h 55m

Santo Domingo Las Americas

Mon 4/27

3:30 pm-11:59 pm

1 stop8h 29m

$462

SyracuseSanto Domingo

SYR - SDQ

SYRSDQ

Syracuse Hancock Intl

Sat 6/13

11:25 am-6:00 pm

1 stop6h 35m

Santo Domingo Las Americas

Wed 7/22

1:55 pm-11:57 pm

1 stop10h 02m

$486

SyracuseSanto Domingo

SYR - SDQ

SYRSDQ

Syracuse Hancock Intl

Sun 4/19

6:03 pm-4:29 pm

2 stops22h 26m

Santo Domingo Las Americas

Sun 4/26

2:35 pm-10:41 am

1 stop20h 06m

$509

SyracuseSanto Domingo

SYR - SDQ

SYRSDQ

Syracuse Hancock Intl

Sat 5/23

7:30 pm-12:45 pm

1 stop17h 15m

Santo Domingo Las Americas

Mon 6/1

1:45 pm-10:22 am

1 stop20h 37m

$527

SyracuseSanto Domingo

SYR - SDQ

SYRSDQ

Syracuse Hancock Intl

Sat 7/25

8:31 pm-12:12 pm

1 stop15h 41m

Santo Domingo Las Americas

Wed 8/19

1:03 pm-4:26 pm

1 stop27h 23m

$622

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/5

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Syracuse to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Santo Domingo in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Santo Domingo

What is the cheapest month to book a flight from Syracuse to Santo Domingo?

Currently, April is the cheapest month in which you can book a flight from Syracuse to Santo Domingo (average of $169). Flying from Syracuse to Santo Domingo in August is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated March 9, 2026.
Read through reviews of airlines operating flights from Syracuse to Santo Domingo, such as Delta and JetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,271 reviews

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,271 reviews
Delta
7.9
Good
8,271 reviews

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,899 reviews
Delta
7.9
Good
8,271 reviews

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Santo Domingo?

    Departing from Syracuse to Santo Domingo will take you 9h 59m. There are 1745 mi between Syracuse and Santo Domingo. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Syracuse to Santo Domingo round-trip?

    Our cheapest airline available from Syracuse to Santo Domingo is JetBlue. Our recent data shows that you can find tickets from as low as $330 on this airline. An additional option worth looking into is Delta, starting at $398. JetBlue is priced at 44% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Syracuse to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Syracuse to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Santo Domingo.

  • Can I find deals for business class flights from Syracuse to Santo Domingo?

    Yes. Cheapflights offers flight deals from Syracuse to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Santo Domingo?

    Currently, April is the cheapest month in which you can book a flight from Syracuse to Santo Domingo (average of $169). Flying from Syracuse to Santo Domingo in August is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Syracuse to Santo Domingo

Discover the top 2 airlines that operate flights from Syracuse to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$330Average$616FlexibilityNo cancel feeOn-time62%
DeltaCheapest$398Average$517FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.