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Santo Domingo

$342+ Cheap flights from Portland, ME (PWM) to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SDQ
Dec 16 — Dec 231
Tue 12/16
Tue 12/23
1 adult, Economy
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Find flight deals from Portland to Santo Domingo

Best flights from Portland to Santo Domingo
Discover carefully curated flight deals from Portland to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 16, 2025.

This Delta deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/302:35 pmPWM - SDQ
1 stop8h 55mDelta
Wed 2/47:30 amSDQ - PWM
1 stop7h 15mDelta
Deal found 11/15$342
This American Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/305:07 pmPWM - SDQ
2 stops18h 14mAmerican Airlines
Tue 2/31:23 pmSDQ - PWM
2 stops11h 20mAmerican Airlines
Deal found 11/14$346
This United Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/43:12 pmPWM - SDQ
1 stop7h 34mUnited Airlines
Tue 2/104:18 pmSDQ - PWM
1 stop8h 12mUnited Airlines
Deal found 11/15$382
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3011:29 amPWM - SDQ
2 stops21h 30mMultiple Airlines
Tue 2/311:14 amSDQ - PWM
1 stop24h 03mMultiple Airlines
Deal found 11/14$456
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/45:07 pmPWM - SDQ
2 stops21h 38mAmerican Airlines
Tue 2/106:00 amSDQ - PWM
2 stops17h 54mAmerican Airlines
Deal found 11/15$346
This Delta deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/302:35 pmPWM - SDQ
1 stop8h 57mDelta
Tue 2/37:31 amSDQ - PWM
1 stop7h 14mDelta
Deal found 11/14$360
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:20 pmPWM - SDQ
2 stops19h 10mAmerican Airlines
Mon 4/65:20 pmSDQ - PWM
2 stops18h 40mAmerican Airlines
Deal found 11/16$421
This Delta deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:30 amPWM - SDQ
1 stop7h 45mDelta
Mon 4/67:05 amSDQ - PWM
1 stop16h 44mDelta
Deal found 11/15$471
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/192:35 pmPWM - SDQ
1 stop8h 55mDelta
Sat 1/247:31 amSDQ - PWM
1 stop7h 14mDelta
Deal found 11/16$474
This Delta deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:30 amPWM - SDQ
1 stop17h 12mDelta
Fri 4/37:05 amSDQ - PWM
1 stop16h 44mDelta
Deal found 11/14$474

Cheap flight deals from Portland to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$342
(Delta)
Provider with most accurate pricing for Portland-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Santo Domingo Las Americas flights.
Search Deals
From Portland to Santo Domingo Las Americas
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 16, 2025.
Use the filters below to find and compare flights from Portland to Santo Domingo that are best for you.

Fly from

Portland

Fly to

Santo Domingo

Route

Depart

Return

Price

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 1/30

2:35 pm-12:30 am

1 stop8h 55m

Santo Domingo Las Americas

Wed 2/4

7:30 am-1:45 pm

1 stop7h 15m

$342

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 1/30

5:07 pm-12:21 pm

2 stops18h 14m

Santo Domingo Las Americas

Tue 2/3

1:23 pm-11:43 pm

2 stops11h 20m

$346

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Wed 2/4

5:07 pm-3:45 pm

2 stops21h 38m

Santo Domingo Las Americas

Tue 2/10

6:00 am-10:54 pm

2 stops17h 54m

$346

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 1/30

2:35 pm-12:32 am

1 stop8h 57m

Santo Domingo Las Americas

Tue 2/3

7:31 am-1:45 pm

1 stop7h 14m

$360

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Wed 2/4

3:12 pm-11:46 pm

1 stop7h 34m

Santo Domingo Las Americas

Tue 2/10

4:18 pm-11:30 pm

1 stop8h 12m

$382

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Wed 4/1

5:20 pm-12:30 pm

2 stops19h 10m

Santo Domingo Las Americas

Mon 4/6

5:20 pm-12:00 pm

2 stops18h 40m

$421

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 1/30

11:29 am-9:59 am

2 stops21h 30m

Santo Domingo Las Americas

Tue 2/3

11:14 am-10:17 am

1 stop24h 03m

$456

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Wed 4/1

5:30 am-1:15 pm

1 stop7h 45m

Santo Domingo Las Americas

Mon 4/6

7:05 am-11:49 pm

1 stop16h 44m

$471

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Mon 1/19

2:35 pm-12:30 am

1 stop8h 55m

Santo Domingo Las Americas

Sat 1/24

7:31 am-1:45 pm

1 stop7h 14m

$474

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Mon 3/30

6:30 am-11:42 pm

1 stop17h 12m

Santo Domingo Las Americas

Fri 4/3

7:05 am-11:49 pm

1 stop16h 44m

$474

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/15

Compare providers for flights from Portland to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Santo Domingo in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland, Maine-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland, Maine-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland, Maine-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santo Domingo

What is the cheapest month to book a flight from Portland, Maine to Santo Domingo?

Currently, November is the cheapest month in which you can book a flight from Portland, Maine to Santo Domingo (average of $238). Flying from Portland, Maine to Santo Domingo in July is currently the most expensive (average of $380). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Portland to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Santo Domingo?

    Airlines like Delta and American Airlines fly from Portland, Maine to Santo Domingo in about 8h 55m. The time it takes to get you to your destination can typically vary by up to 9h 19m. The distance from Portland, Maine to Santo Domingo is about 1742 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Portland to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Portland to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santo Domingo.

  • Can I find deals for business class flights from Portland to Santo Domingo?

    Yes. Cheapflights offers flight deals from Portland to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Santo Domingo?

    Currently, November is the cheapest month in which you can book a flight from Portland, Maine to Santo Domingo (average of $238). Flying from Portland, Maine to Santo Domingo in July is currently the most expensive (average of $380). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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