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Santo Domingo

$349+ Cheap flights from Portland, ME (PWM) to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SDQ
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheap flight deals from Portland to Santo Domingo

Cheapest flights from Portland to Santo Domingo
Explore the most affordable flight options available from Portland to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
PWM
-
SDQ
1 stop8h 13m
JetBlue
Wed 5/203:23 pm
SDQ
-
PWM
1 stop8h 13m
JetBlue
Deal found 2/11$349
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:31 am
PWM
-
SDQ
1 stop7h 46m
Delta
Wed 3/43:42 pm
SDQ
-
PWM
1 stop8h 24m
Delta
Deal found 2/11$357
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:30 am
PWM
-
SDQ
1 stop11h 44m
Delta
Tue 3/108:25 pm
SDQ
-
PWM
2 stops15h 44m
Delta
Deal found 2/10$422
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:23 pm
PWM
-
SDQ
2 stops13h 57m
American Airlines
Sun 4/264:00 pm
SDQ
-
PWM
2 stops19h 15m
American Airlines
Deal found 2/9$566
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:00 am
PWM
-
SDQ
2 stops9h 50m
American Airlines
Wed 3/47:00 am
SDQ
-
PWM
2 stops17h 50m
American Airlines
Deal found 2/11$569
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/243:05 pm
PWM
-
SDQ
1 stop7h 41m
United Airlines
Thu 2/264:18 pm
SDQ
-
PWM
2 stops29h 51m
United Airlines
Deal found 2/8$612

Find flight deals from Portland to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$349
(KAYAK)
Provider with most accurate pricing for Portland-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Santo Domingo Las Americas flights.
Search Deals
From Portland to Santo Domingo Las Americas
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Portland to Santo Domingo that are best for you.

Fly from

Portland

Fly to

Santo Domingo

Route

Depart

Return

Price

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Wed 5/13

6:00 am-2:13 pm

1 stop8h 13m

Santo Domingo Las Americas

Wed 5/20

3:23 pm-11:36 pm

1 stop8h 13m

$349

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Mon 3/2

5:31 am-2:17 pm

1 stop7h 46m

Santo Domingo Las Americas

Wed 3/4

3:42 pm-11:06 pm

1 stop8h 24m

$357

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 3/6

6:30 am-7:14 pm

1 stop11h 44m

Santo Domingo Las Americas

Tue 3/10

8:25 pm-12:09 pm

2 stops15h 44m

$422

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Mon 3/2

7:00 am-5:50 pm

2 stops9h 50m

Santo Domingo Las Americas

Wed 3/4

7:00 am-11:50 pm

2 stops17h 50m

$569

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Tue 2/24

3:05 pm-11:46 pm

1 stop7h 41m

Santo Domingo Las Americas

Thu 2/26

4:18 pm-9:09 pm

2 stops29h 51m

$612

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

  • Most accurate provider: When it comes to deals on Portland, Maine-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santo Domingo

What is the cheapest month to book a flight from Portland, Maine to Santo Domingo?

Currently, November is the cheapest month in which you can book a flight from Portland, Maine to Santo Domingo (average of $215). Flying from Portland, Maine to Santo Domingo in July is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Portland to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Santo Domingo?

    Airlines like JetBlue and Delta fly from Portland, Maine to Santo Domingo in about 7h 46m. The time it takes to get you to your destination can typically vary by up to 27m. The distance from Portland, Maine to Santo Domingo is about 1742 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Portland to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Portland to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santo Domingo.

  • Can I find deals for business class flights from Portland to Santo Domingo?

    Yes. Cheapflights offers flight deals from Portland to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Santo Domingo?

    Currently, November is the cheapest month in which you can book a flight from Portland, Maine to Santo Domingo (average of $215). Flying from Portland, Maine to Santo Domingo in July is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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