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Santo Domingo

$238+ Cheap flights from Mexico City (MEX) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — SDQ
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Mexico City Benito Juarez to Santo Domingo Las Americas are usually found in May or June, booked 64 days in advance, depart on a Monday or Sunday and return on a Friday

Cheap flight deals from Mexico City to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$332
(Kiwi.com)

One-way from

$238
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$342

Good round-trip deal

$160 or less

Good one-way deal

$159 or less
From Mexico City Benito Juarez to Santo Domingo Las Americas
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One-way flight from Mexico City Benito Juarez to Santo Domingo Las Americas
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Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Mexico City Benito Juarez to Santo Domingo Las Americas.
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Price to beat on a one-way flight from Mexico City Benito Juarez to Santo Domingo Las Americas.
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Find flight deals from Mexico City to Santo Domingo

Cheapest flights from Mexico City to Santo Domingo
Explore the most affordable flight options available from Mexico City to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/81:05 pmMEX - SDQ
1 stop7h 20mCopa Airlines
Wed 10/156:24 pmSDQ - MEX
1 stop7h 51mCopa Airlines
Deal found 9/9$332
This Aeromexico deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2912:25 amMEX - SDQ
Nonstop4h 26mAeromexico
Tue 10/711:01 amSDQ - MEX
Nonstop4h 49mAeromexico
Deal found 9/11$335
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/249:50 amMEX - SDQ
1 stop10h 36mCopa Airlines
Wed 10/111:57 amSDQ - MEX
1 stop15h 03mCopa Airlines
Deal found 9/10$336
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/291:05 pmMEX - SDQ
1 stop11h 31mCopa Airlines
Fri 10/108:58 amSDQ - MEX
1 stop15h 07mCopa Airlines
Deal found 9/10$348
This Aeromexico deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/201:01 amMEX - SDQ
Nonstop4h 20mAeromexico
Sun 11/3011:01 amSDQ - MEX
Nonstop4h 54mAeromexico
Deal found 9/11$358
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/251:05 pmMEX - SDQ
1 stop7h 21mCopa Airlines
Sun 9/2811:56 amSDQ - MEX
1 stop12h 09mCopa Airlines
Deal found 9/11$393
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/292:00 amMEX - SDQ
1 stop6h 58mCopa Airlines
Sun 11/25:00 amSDQ - MEX
1 stop21h 00mCopa Airlines
Deal found 9/10$399
This Aeromexico deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/281:01 amMEX - SDQ
Nonstop4h 20mAeromexico
Sat 12/1311:01 amSDQ - MEX
Nonstop4h 54mAeromexico
Deal found 9/10$400
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/11:05 pmMEX - SDQ
1 stop7h 20mCopa Airlines
Sun 10/52:10 pmSDQ - MEX
1 stop12h 50mCopa Airlines
Deal found 9/9$401
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:50 amMEX - SDQ
1 stop8h 27mCopa Airlines
Tue 9/3011:56 amSDQ - MEX
1 stop12h 09mCopa Airlines
Deal found 9/11$402
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/201:05 pmMEX - SDQ
1 stop7h 21mCopa Airlines
Sat 9/272:09 pmSDQ - MEX
1 stop12h 06mCopa Airlines
Deal found 9/10$404

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Mexico City to Santo Domingo that are best for you.

Fly from

Mexico City

Fly to

Santo Domingo

Route

Depart

Return

Price

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Tue 9/30

1:05 pm-10:26 pm

1 stop7h 21m

Santo Domingo Las Americas

Tue 10/7

11:57 am-12:15 am

1 stop14h 18m

$336

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Mon 3/2

1:20 am-1:11 pm

1 stop9h 51m

Santo Domingo Las Americas

Thu 3/12

6:00 am-7:20 pm

1 stop15h 20m

$360

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Fri 1/30

5:55 am-4:12 pm

1 stop8h 17m

Santo Domingo Las Americas

Wed 2/4

8:50 am-7:20 pm

1 stop12h 30m

$401

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Thu 2/19

2:00 am-4:12 pm

1 stop12h 12m

Santo Domingo Las Americas

Tue 2/24

11:57 am-12:15 am

1 stop14h 18m

$401

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Mon 3/2

1:10 pm-2:18 am

1 stop11h 08m

Santo Domingo Las Americas

Sun 3/8

6:00 am-7:20 pm

1 stop15h 20m

$401

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Wed 2/18

1:20 am-1:09 pm

1 stop9h 49m

Santo Domingo Las Americas

Tue 2/24

6:39 pm-12:15 am

1 stop7h 36m

$401

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Tue 1/20

1:20 am-4:12 pm

1 stop12h 52m

Santo Domingo Las Americas

Fri 1/30

12:40 pm-7:20 pm

1 stop8h 40m

$412

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Wed 12/3

9:25 am-2:26 am

1 stop15h 01m

Santo Domingo Las Americas

Fri 1/23

8:50 am-7:20 pm

1 stop12h 30m

$412

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Wed 9/24

3:30 pm-2:36 am

1 stop9h 06m

Santo Domingo Las Americas

Sun 9/28

8:59 am-12:15 am

1 stop17h 16m

$419

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Fri 10/3

6:30 pm-2:42 pm

2 stops18h 12m

$238

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 20 results
1
2

Best time to book a flight from Mexico City to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Santo Domingo

How far ahead should I book a flight from Mexico City to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Santo Domingo. Price data was last updated on August 29, 2025.

To ensure you get the cheapest price possible for a flight from Mexico City to Santo Domingo, you should look to book at least 64 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mexico City to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Mexico City to Santo Domingo (average of $362). Flying from Mexico City to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to SDQ?

Find hourly flight availability from Mexico City to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s optimal to fly from Mexico City to Santo Domingo in the morning. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the evening.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Copa Airlines and Aeromexico from Mexico City to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Comfort

7.4

Boarding

7.8

Crew

8.1

Food

6.8

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Comfort

7.4

Boarding

7.8

Crew

8.1

Food

6.8

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Aeromexico
7.5
Good
1,701 reviews
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Comfort

7.4

Boarding

7.8

Crew

8.1

Food

6.8

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Mexico City to Santo Domingo?

    If you book a flight from Mexico City to Santo Domingo, you will be flying from Benito Juarez to Las Americas. Flights to Santo Domingo Las Americas (SDQ) from Mexico City Benito Juarez (MEX) take 4h 25m for a nonstop flight. There is 1 flight from Benito Juarez to Santo Domingo per day from 3 airlines.

  • How long is the flight from Mexico City to Santo Domingo?

    Departing from Mexico City to Santo Domingo will take you 7h 21m. Airlines will cover a distance of 1919 mi.

  • What are the cheapest airlines flying from Mexico City to Santo Domingo round-trip?

    Cheapflights users have booked flights from Mexico City to Santo Domingo round-trip from $175. Other airlines that can offer you cheap pricing are Copa Airlines, from $272, and Aeromexico, from $330. Arajet is priced at 49% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Mexico City to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Mexico City to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Santo Domingo.

  • Can I find deals for business class flights from Mexico City to Santo Domingo?

    Yes. Cheapflights offers flight deals from Mexico City to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Mexico City to Santo Domingo (average of $362). Flying from Mexico City to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mexico City to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
Mexico City to Punta Cana flights
Mexico City to Santiago de los Caballeros flights

Top 3 airlines flying from Mexico City to Santo Domingo

Discover the top 3 airlines that operate flights from Mexico City to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
ArajetCheapest$175Average$319FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$272Average$439FlexibilityNo cancel feeOn-time70%
AeromexicoCheapest$330Average$455FlexibilityNo cancel feeOn-timeN/A

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