What is the cheapest airline to fly from Knoxville to Santo Domingo round-trip?

Cheapflights users have booked flights from Knoxville to Santo Domingo round-trip from $474. American Airlines is currently priced 32% below the average price you’ll pay for this route.

What is the cheapest day to fly from Knoxville to Santo Domingo?

Travelers seeking maximum savings on their Knoxville to Santo Domingo flight should consider departing on Wednesday mornings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What is the cheapest day to fly round-trip from Knoxville to Santo Domingo?

Users have found that flying from Knoxville to Santo Domingo on a Sunday typically leans towards higher prices. However, this doesn’t mean you still can’t find a deal. Flexibility with other aspects of your flight can still land a great price for your trip.

What is the cheapest month to fly from Knoxville to Santo Domingo?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, October can be a great choice for travel to Santo Domingo. Flights to Santo Domingo from Knoxville in October are about $700 on average during October, but can be found for as low as $470.

What is the cheapest time of day to fly from TYS to SDQ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Santo Domingo as you normally would.

Can I find deals for flights from Knoxville to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Knoxville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Santo Domingo.

Can I find deals for business class flights from Knoxville to Santo Domingo?

Yes. Cheapflights offers flight deals from Knoxville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Cheap flight deals from Knoxville to Santo Domingo

Popular in	December
Cheapest in	October
Average price	$634

Highest demand for flights based on searches. 10% potential increase in price ($83 potential increase over avg. RT price).

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Cheapest flight prices on average. 5% potential price decrease ($37 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Best time to book a flight from Knoxville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Santo Domingo

What is the cheapest month to book a flight from Knoxville to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Santo Domingo (average of $362). Flying from Knoxville to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Peruse reviews from past customers who have flown with American Airlines from Knoxville to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

What is the cheapest airline to fly from Knoxville to Santo Domingo round-trip?
Cheapflights users have booked flights from Knoxville to Santo Domingo round-trip from $474. American Airlines is currently priced 32% below the average price you’ll pay for this route.
Can I find deals for flights from Knoxville to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Knoxville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Santo Domingo.
Can I find deals for business class flights from Knoxville to Santo Domingo?
Yes. Cheapflights offers flight deals from Knoxville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Santo Domingo (average of $362). Flying from Knoxville to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

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Top airline flying from Knoxville to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$474	Average$731	FlexibilityNo cancel fee	On-time71%

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Cheap flights from Knoxville (TYS) to Santo Domingo (SDQ)

Find cheap flights from Knoxville to Santo Domingo with Cheapflights

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2. Select your favorite providers

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Cheap flight deals from Knoxville to Santo Domingo

Popular in

Cheapest in

Average price

Best time to book a flight from Knoxville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Santo Domingo

What is the cheapest month to book a flight from Knoxville to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Peruse reviews from past customers who have flown with American Airlines from Knoxville to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What is the cheapest airline to fly from Knoxville to Santo Domingo round-trip?

Can I find deals for flights from Knoxville to Santo Domingo that include hotel bookings?

How can I find direct flights from Knoxville to Santo Domingo?

Can I find deals for business class flights from Knoxville to Santo Domingo?

What is the cheapest month to book a flight from Knoxville to Santo Domingo?

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Top airline flying from Knoxville to Santo Domingo

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