What are the cheapest airlines flying from Harrisburg to Santo Domingo round-trip?

Flying on American Airlines is currently your cheapest option to Santo Domingo, with prices starting at $478. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $679 and $936, respectively. These flights start at 32% lower than the current average price 3 months from now.

What are the cheapest airlines to fly from Harrisburg to Santo Domingo one-way?

The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $222. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Harrisburg to Santo Domingo for a low price.

What is the cheapest day to fly from Harrisburg to Santo Domingo?

Travelers seeking maximum savings on their Harrisburg to Santo Domingo flight should consider departing on Tuesday mornings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What is the cheapest day to fly round-trip from Harrisburg to Santo Domingo?

Friday flights are found to be more expensive to fly from Harrisburg to Santo Domingo. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Santo Domingo.

What is the cheapest month to fly from Harrisburg to Santo Domingo?

The best pricing can be found in the month of September. Prices to Santo Domingo from Harrisburg average $705. You can even find prices in September for less than $705, as users have found deals to Santo Domingo from as low as $364. The month of December appears to be one of the more expensive times to travel to Santo Domingo from Harrisburg. Flying in the targeted month can save you up to 119%.

Can I find deals for flights from Harrisburg to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Harrisburg to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Harrisburg to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Santo Domingo.

Can I find deals for business class flights from Harrisburg to Santo Domingo?

Yes. Cheapflights offers flight deals from Harrisburg to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$222+ Flights from Harrisburg to Santo Domingo

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Cheap flight deals from Harrisburg to Santo Domingo

Round-trip from	$422 (Mytrip)
One-way from	$222 (Delta)
Popular in	December
Cheapest in	September
Average price	$668

From Harrisburg to Santo Domingo Las Americas

Search Deals

One-way flight from Harrisburg to Santo Domingo Las Americas

Search Deals

Highest demand for flights based on searches. 23% potential increase in price ($215 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 12% potential price decrease ($78 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Harrisburg to Santo Domingo

Cheapest flights from Harrisburg to Santo Domingo
Explore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

dom. 7/137:00 pmMDT - SDQ

1 stop14h 50mMultiple Airlines

dom. 7/2010:55 amSDQ - MDT

1 stop7h 15mMultiple Airlines

Deal found 7/2

$422

mar. 8/192:49 pmMDT - SDQ

2 stops18h 36mAmerican Airlines

mar. 8/264:25 pmSDQ - MDT

2 stops17h 40mAmerican Airlines

Deal found 7/1

$478

mar. 8/196:00 amMDT - SDQ

1 stop7h 22mDelta

mar. 8/262:47 pmSDQ - MDT

1 stop7h 37mDelta

Deal found 7/1

$679

sáb. 8/168:30 amMDT - SDQ

2 stops17h 20mUnited Airlines

sáb. 8/233:20 pmSDQ - MDT

2 stops22h 28mUnited Airlines

Deal found 7/2

$936

Best flights from Harrisburg to Santo Domingo
Discover carefully curated flight deals from Harrisburg to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated julio 3, 2025.

dom. 7/137:00 pmMDT - SDQ

1 stop14h 50mMultiple Airlines

dom. 7/2010:55 amSDQ - MDT

1 stop7h 15mMultiple Airlines

Deal found 7/2

$422

mar. 8/192:49 pmMDT - SDQ

2 stops18h 36mAmerican Airlines

mar. 8/264:25 pmSDQ - MDT

2 stops17h 40mAmerican Airlines

Deal found 7/1

$478

mar. 8/196:00 amMDT - SDQ

1 stop7h 22mDelta

mar. 8/262:47 pmSDQ - MDT

1 stop7h 37mDelta

Deal found 7/1

$679

sáb. 8/168:30 amMDT - SDQ

2 stops17h 20mUnited Airlines

sáb. 8/233:20 pmSDQ - MDT

2 stops22h 28mUnited Airlines

Deal found 7/2

$936

Last-minute flights from Harrisburg to Santo Domingo
Discover last-minute flight deals from Harrisburg to Santo Domingo. Data last updated julio 3, 2025 and is based on user searches.

dom. 7/137:00 pmMDT - SDQ

1 stop14h 50mMultiple Airlines

dom. 7/2010:55 amSDQ - MDT

1 stop7h 15mMultiple Airlines

Deal found 7/2

$422

dom. 7/136:00 amMDT - SDQ

1 stop7h 12mDelta

lun. 7/282:38 pmSDQ - MDT

1 stop9h 14mDelta

Deal found 7/2

$1,250

sáb. 8/168:30 amMDT - SDQ

2 stops17h 20mUnited Airlines

sáb. 8/233:20 pmSDQ - MDT

2 stops22h 28mUnited Airlines

Deal found 7/2

$936

mar. 8/192:49 pmMDT - SDQ

2 stops18h 36mAmerican Airlines

mar. 8/264:25 pmSDQ - MDT

2 stops17h 40mAmerican Airlines

Deal found 7/1

$478

mar. 8/196:00 amMDT - SDQ

1 stop7h 22mDelta

mar. 8/262:47 pmSDQ - MDT

1 stop7h 37mDelta

Deal found 7/1

$679

One-way flights from Harrisburg to Santo Domingo
Search for one-way flight options from Harrisburg to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated julio 3, 2025.

mié. 11/196:00 amMDT - SDQ

1 stop7h 57mDelta

Deal found 7/1

$222

jue. 7/107:00 pmMDT - SDQ

1 stop14h 50mMultiple Airlines

Deal found 7/1

$225

mié. 11/196:40 amMDT - SDQ

2 stops7h 55mAmerican Airlines

Deal found 7/1

$226

mié. 11/196:15 amMDT - SDQ

3 stops16h 31mUnited Airlines

Deal found 7/1

$267

Cheapflights Fare Finder

Use the filters below to find and compare flights from Harrisburg to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

dom. 7/13

7:00 pm-9:50 am

1 stop14h 50m

Santo Domingo Las Americas

dom. 7/20

10:55 am-6:10 pm

1 stop7h 15m

$422

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

mar. 8/19

2:49 pm-9:25 am

2 stops18h 36m

Santo Domingo Las Americas

mar. 8/26

4:25 pm-10:05 am

2 stops17h 40m

$478

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

mar. 8/19

6:00 am-1:22 pm

1 stop7h 22m

Santo Domingo Las Americas

mar. 8/26

2:47 pm-10:24 pm

1 stop7h 37m

$679

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

sáb. 8/16

8:30 am-1:50 am

2 stops17h 20m

Santo Domingo Las Americas

sáb. 8/23

3:20 pm-1:48 pm

2 stops22h 28m

$936

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

mié. 11/19

6:00 am-2:57 pm

1 stop7h 57m

$222

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

jue. 7/10

7:00 pm-9:50 am

1 stop14h 50m

$225

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

mié. 11/19

6:40 am-3:35 pm

2 stops7h 55m

$226

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

mié. 11/19

6:15 am-11:46 pm

3 stops16h 31m

$267

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Harrisburg to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Harrisburg with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Santo Domingo

What is the cheapest month to book a flight from Harrisburg to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Harrisburg to Santo Domingo (average of $362). Flying from Harrisburg to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to SDQ?

When flying from Harrisburg to Santo Domingo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Santo Domingo

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Harrisburg to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,982 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,861 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Harrisburg to Santo Domingo round-trip?
Flying on American Airlines is currently your cheapest option to Santo Domingo, with prices starting at $478. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $679 and $936, respectively. These flights start at 32% lower than the current average price 3 months from now.
What are the cheapest airlines to fly from Harrisburg to Santo Domingo one-way?
The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $222. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Harrisburg to Santo Domingo for a low price.
Can I find deals for flights from Harrisburg to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Harrisburg to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Harrisburg to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Santo Domingo.
Can I find deals for business class flights from Harrisburg to Santo Domingo?
Yes. Cheapflights offers flight deals from Harrisburg to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Harrisburg to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Harrisburg to Santo Domingo (average of $362). Flying from Harrisburg to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Harrisburg to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$356	Average$539	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$414	Average$731	FlexibilityNo cancel fee	On-time71%

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$222+ Cheap flights from Harrisburg (MDT) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Harrisburg to Santo Domingo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Harrisburg to Santo Domingo

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Harrisburg to Santo Domingo

Cheapest flights from Harrisburg to Santo DomingoExplore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

Explore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Harrisburg to Santo Domingo that are best for you.

Best time to book a flight from Harrisburg to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Harrisburg with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Santo Domingo

What is the cheapest month to book a flight from Harrisburg to Santo Domingo?

What is the cheapest time of day to fly from MDT to SDQ?

Find hourly flight availability from Harrisburg to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 3, 2025.

Reviews of airlines servicing Santo Domingo

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Harrisburg to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Harrisburg to Santo Domingo round-trip?

What are the cheapest airlines to fly from Harrisburg to Santo Domingo one-way?

Can I find deals for flights from Harrisburg to Santo Domingo that include hotel bookings?

How can I find direct flights from Harrisburg to Santo Domingo?

Can I find deals for business class flights from Harrisburg to Santo Domingo?

What is the cheapest month to book a flight from Harrisburg to Santo Domingo?

Traveling to a place near Harrisburg?

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Alternative routes for Harrisburg to Santo Domingo

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Top 2 airlines flying from Harrisburg to Santo Domingo

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Cheapest flights from Harrisburg to Santo Domingo
Explore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.