How popular is this Key Largo to Santiago de los Caballeros flight route?

Flights from Key Largo to Santiago de los Caballeros have been viewed 2 times in the past calendar month.

What are the cheapest airlines to fly from Key Largo to Santiago de los Caballeros one-way?

The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $144. However, be on the lookout for offers from Spirit Airlines and American Airlines, as they are both options that can get you from Key Largo to Santiago de los Caballeros for a low price.

What are the most popular airlines that fly from Key Largo to Santiago de los Caballeros?

The most popular airlines flying from Key Largo to Santiago de los Caballeros are American Airlines, JetBlue and Copa Airlines. Something to consider prior to booking your flight.

What is the cheapest month to fly from Key Largo to Santiago de los Caballeros?

October is one of the best times of the year to fly to Santiago de los Caballeros from Key Largo. Prices for October average $477 per person but you can even find prices for as low as $257. The most expensive prices can be found in the month of December. Opting for a October flight can save you 37% on your journey compared to booking in December

What airport do you fly into for flights to Santiago de los Caballeros from Key Largo?

Most people fly into Santiago de los Caballeros (STI) if they book a flight to Santiago de los Caballeros from Key Largo. On average, Santiago has 1 inbound flight from Key Largo per day from 5 airlines. Santiago de los Caballeros is conveniently located just 6.8 mi from Santiago de los Caballeros’s city center.

How can I find direct flights from Key Largo to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Santiago de los Caballeros.

Can I find deals for business class flights from Key Largo to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Key Largo to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$144+ Flights from Key Largo to Santiago de los Caballeros

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Cheapflights Tip: The best prices from Key Largo to Santiago de los Caballeros are usually found in October or September, booked 85 days in advance, depart on a Thursday or Wednesday and return on a Friday

Cheap flight deals from Key Largo to Santiago de los Caballeros

Round-trip from	$296 (Priceline)
One-way from	$144 (Priceline)
Popular in	December
Cheapest in	October
Average price	$425

From Key Largo to Santiago de los Caballeros

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One-way flight from Key Largo to Santiago de los Caballeros

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Highest demand for flights based on searches. 11% potential increase in price ($59 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).

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Average for round-trip flights in June 2025

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Find flight deals from Key Largo to Santiago de los Caballeros

Cheapest flights from Key Largo to Santiago de los Caballeros
Explore the most affordable flight options available from Key Largo to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

mar. 8/123:40 pmMIA - STI

1 stop21h 11mFrontier

jue. 8/211:26 pmSTI - MIA

1 stop10h 21mFrontier

Deal found 6/12

$296

mar. 8/126:43 pmMIA - STI

Nonstop2h 05mAmerican Airlines

jue. 8/217:00 amSTI - MIA

Nonstop2h 10mAmerican Airlines

Deal found 6/12

$392

sáb. 9/67:00 amMIA - STI

1 stop12h 24mDelta

sáb. 9/206:20 amSTI - MIA

1 stop12h 19mDelta

Deal found 6/10

$407

mar. 6/176:33 pmMIA - STI

1 stop18h 17mMultiple Airlines

lun. 6/302:10 pmSTI - MIA

1 stop9h 27mMultiple Airlines

Deal found 6/11

$416

sáb. 7/52:53 pmMIA - STI

2 stops19h 36mSpirit Airlines

sáb. 7/1210:55 amSTI - MIA

2 stops29h 58mSpirit Airlines

Deal found 6/12

$458

Best flights from Key Largo to Santiago de los Caballeros
Discover carefully curated flight deals from Key Largo to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated junio 12, 2025.

mar. 8/123:40 pmMIA - STI

1 stop21h 11mFrontier

jue. 8/211:26 pmSTI - MIA

1 stop10h 21mFrontier

Deal found 6/12

$296

mar. 8/126:43 pmMIA - STI

Nonstop2h 05mAmerican Airlines

jue. 8/217:00 amSTI - MIA

Nonstop2h 10mAmerican Airlines

Deal found 6/12

$392

sáb. 9/67:00 amMIA - STI

1 stop12h 24mDelta

sáb. 9/206:20 amSTI - MIA

1 stop12h 19mDelta

Deal found 6/10

$407

mar. 6/176:33 pmMIA - STI

1 stop18h 17mMultiple Airlines

lun. 6/302:10 pmSTI - MIA

1 stop9h 27mMultiple Airlines

Deal found 6/11

$416

sáb. 7/52:53 pmMIA - STI

2 stops19h 36mSpirit Airlines

sáb. 7/1210:55 amSTI - MIA

2 stops29h 58mSpirit Airlines

Deal found 6/12

$458

Last-minute flights from Key Largo to Santiago de los Caballeros
Discover last-minute flight deals from Key Largo to Santiago de los Caballeros. Data last updated junio 12, 2025 and is based on user searches.

mar. 6/173:40 pmMIA - STI

1 stop21h 10mFrontier

mié. 7/22:10 pmSTI - MIA

1 stop8h 18mFrontier

Deal found 6/11

$305

mar. 6/176:33 pmMIA - STI

1 stop18h 17mMultiple Airlines

lun. 6/302:10 pmSTI - MIA

1 stop9h 27mMultiple Airlines

Deal found 6/11

$416

mar. 6/176:55 pmMIA - STI

Nonstop2h 10mAmerican Airlines

mar. 6/241:35 pmSTI - MIA

Nonstop2h 15mAmerican Airlines

Deal found 6/10

$510

mar. 6/175:19 pmMIA - STI

1 stop8h 27mUnited Airlines

mar. 6/246:00 amSTI - MIA

1 stop10h 11mUnited Airlines

Deal found 6/10

$850

mar. 6/172:34 pmMIA - STI

1 stop9h 22mJetBlue

mar. 6/244:20 amSTI - MIA

1 stop9h 18mJetBlue

Deal found 6/10

$933

mié. 6/182:53 pmMIA - STI

2 stops19h 36mSpirit Airlines

mar. 6/2411:29 amSTI - MIA

2 stops33h 46mSpirit Airlines

Deal found 6/10

$621

sáb. 7/52:53 pmMIA - STI

2 stops19h 36mSpirit Airlines

sáb. 7/1210:55 amSTI - MIA

2 stops29h 58mSpirit Airlines

Deal found 6/12

$458

sáb. 7/57:04 pmMIA - STI

Nonstop2h 15mAmerican Airlines

dom. 7/207:04 amSTI - MIA

Nonstop2h 10mAmerican Airlines

Deal found 6/10

$485

One-way flights from Key Largo to Santiago de los Caballeros
Search for one-way flight options from Key Largo to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated junio 12, 2025.

mar. 6/243:40 pmMIA - STI

1 stop21h 10mFrontier

Deal found 6/10

$144

jue. 7/1011:10 amMIA - STI

2 stops22h 40mSpirit Airlines

Deal found 6/10

$200

dom. 7/206:00 amMIA - STI

2 stops27h 50mMultiple Airlines

Deal found 6/11

$243

lun. 8/47:04 pmMIA - STI

Nonstop2h 15mAmerican Airlines

Deal found 6/12

$251

mié. 8/277:00 amMIA - STI

1 stop12h 24mDelta

Deal found 6/10

$256

mié. 8/1311:43 amMIA - STI

1 stop14h 00mJetBlue

Deal found 6/11

$336

mié. 7/26:22 amMIA - STI

1 stop8h 50mUnited Airlines

Deal found 6/10

$486

mié. 7/29:30 pmMIA - STI

1 stop22h 35mAir Europa

Deal found 6/12

$3,869

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key Largo to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

mar. 8/12

3:40 pm-12:51 pm

1 stop21h 11m

Santiago de los Caballeros

jue. 8/21

1:26 pm-11:47 pm

1 stop10h 21m

$296

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

mar. 8/12

6:43 pm-8:48 pm

Nonstop2h 05m

Santiago de los Caballeros

jue. 8/21

7:00 am-9:10 am

Nonstop2h 10m

$392

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

sáb. 9/6

7:00 am-7:24 pm

1 stop12h 24m

Santiago de los Caballeros

sáb. 9/20

6:20 am-6:39 pm

1 stop12h 19m

$407

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

mié. 8/6

2:48 pm-9:50 am

2 stops19h 02m

Santiago de los Caballeros

vie. 8/8

2:06 pm-8:04 pm

1 stop5h 58m

$418

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

sáb. 7/5

2:53 pm-10:29 am

2 stops19h 36m

Santiago de los Caballeros

sáb. 7/12

10:55 am-4:53 pm

2 stops29h 58m

$458

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

mar. 6/24

3:40 pm-12:50 pm

1 stop21h 10m

$144

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

jue. 7/10

11:10 am-9:50 am

2 stops22h 40m

$200

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

dom. 7/20

6:00 am-9:50 am

2 stops27h 50m

$243

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

lun. 8/4

7:04 pm-9:19 pm

Nonstop2h 15m

$251

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

sáb. 10/11

7:30 am-6:38 pm

1 stop11h 08m

$256

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 12 results

Best time to book a flight from Key Largo to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Key Largo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Santiago de los Caballeros

How far ahead should I book a flight from Key Largo to Santiago de los Caballeros?

The best time to book flights from Key Largo to Santiago de los Caballeros is 85 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Key Largo to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Key Largo to Santiago de los Caballeros (average of $347). Flying from Key Largo to Santiago de los Caballeros in July is currently the most expensive (average of $630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to STI?

When flying from Key Largo to Santiago de los Caballeros, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to Santiago de los Caballeros?

Travelers seeking maximum savings on their Key Largo to Santiago de los Caballeros flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to Santiago de los Caballeros

The most flights from KE9 to STI are scheduled on a Monday (2 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in Santiago de los Caballeros by month

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

Temperature in Santiago de los Caballeros by month

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Santiago de los Caballeros

Read reviews from past customers who have flown Delta, United Airlines and JetBlue from Key Largo to Santiago de los Caballeros. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Delta

8.0

Very good

7,950 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

United Airlines

7.4

Good

8,790 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

JetBlue

7.3

Good

2,925 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Air Europa

6.9

Okay

529 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Related info for your journey

What airport do you fly into for flights to Santiago de los Caballeros from Key Largo?
Most people fly into Santiago de los Caballeros (STI) if they book a flight to Santiago de los Caballeros from Key Largo. On average, Santiago has 1 inbound flight from Key Largo per day from 5 airlines. Santiago de los Caballeros is conveniently located just 6.8 mi from Santiago de los Caballeros’s city center.
How popular is this Key Largo to Santiago de los Caballeros flight route?
Flights from Key Largo to Santiago de los Caballeros have been viewed 2 times in the past calendar month.
What are the cheapest airlines to fly from Key Largo to Santiago de los Caballeros one-way?
The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $144. However, be on the lookout for offers from Spirit Airlines and American Airlines, as they are both options that can get you from Key Largo to Santiago de los Caballeros for a low price.
What are the cheapest flights from Key Largo to Santiago de los Caballeros?
On average you can expect to pay $707 for a flight from Key Largo to Santiago de los Caballeros. The cheapest flight overall is $183 while the most popular route, (Miami - Santiago de los Caballeros) is currently priced at $407.
Can I find deals for flights from Key Largo to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Key Largo to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Key Largo to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Santiago de los Caballeros.
Can I find deals for business class flights from Key Largo to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Key Largo to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Key Largo to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from Key Largo to Santiago de los Caballeros (average of $347). Flying from Key Largo to Santiago de los Caballeros in July is currently the most expensive (average of $630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Key Largo to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$225	Average$284	FlexibilityNo cancel fee	On-time62%
Spirit Airlines	Cheapest$248	Average$356	FlexibilityNo cancel fee	On-time65%
Copa Airlines	Cheapest$303	Average$343	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$327	Average$493	FlexibilityNo cancel fee	On-time71%
JetBlue	Cheapest$354	Average$491	FlexibilityNo cancel fee	On-time62%

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$144+ Cheap flights from Key Largo, FL to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Key Largo to Santiago de los Caballeros with Cheapflights

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Cheapflights Tip: The best prices from Key Largo to Santiago de los Caballeros are usually found in October or September, booked 85 days in advance, depart on a Thursday or Wednesday and return on a Friday

Cheap flight deals from Key Largo to Santiago de los Caballeros

Keep the following information in mind while searching for Key Largo to Santiago de los Caballeros flight deals. Data was last updated junio 12, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Key Largo to Santiago de los Caballeros

Cheapest flights from Key Largo to Santiago de los CaballerosExplore the most affordable flight options available from Key Largo to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

Explore the most affordable flight options available from Key Largo to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key Largo to Santiago de los Caballeros that are best for you.

Best time to book a flight from Key Largo to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Key Largo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Santiago de los Caballeros

How far ahead should I book a flight from Key Largo to Santiago de los Caballeros?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to Santiago de los Caballeros. Price data was last updated on June 9, 2025.

What is the cheapest month to book a flight from Key Largo to Santiago de los Caballeros?

What is the cheapest time of day to fly from KE9 to STI?

Find hourly flight availability from Key Largo to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

What is the cheapest day to fly from Key Largo to Santiago de los Caballeros?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Santiago de los Caballeros. Price data was last updated on December 16, 2024.

Weekly flight availability from Key Largo to Santiago de los Caballeros

Rainfall in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average rainfall totals by month.

Temperature in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago de los Caballeros

Read reviews from past customers who have flown Delta, United Airlines and JetBlue from Key Largo to Santiago de los Caballeros. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santiago de los Caballeros from Key Largo?

How popular is this Key Largo to Santiago de los Caballeros flight route?

What are the cheapest airlines to fly from Key Largo to Santiago de los Caballeros one-way?

What are the cheapest flights from Key Largo to Santiago de los Caballeros?

Can I find deals for flights from Key Largo to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Key Largo to Santiago de los Caballeros?

Can I find deals for business class flights from Key Largo to Santiago de los Caballeros?

What is the cheapest month to book a flight from Key Largo to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Key Largo to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Key Largo to Santiago de los Caballeros

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Cheapest flights from Key Largo to Santiago de los Caballeros
Explore the most affordable flight options available from Key Largo to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.