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Santiago de los Caballeros

$137+ Cheap flights from Key Largo, FL to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — STI
Aug 18 — Aug 251
Mon 8/18
Mon 8/25
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to Santiago de los Caballeros are usually found in September or February, booked 85 days in advance, depart on a Thursday or Wednesday and return on a Friday

Cheap flight deals from Key Largo to Santiago de los Caballeros

Keep the following information in mind while searching for Key Largo to Santiago de los Caballeros flight deals. Data was last updated August 13, 2025.

Round-trip from

$260
(American Airlines)

One-way from

$137
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$450
From Key Largo to Santiago de los Caballeros
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One-way flight from Key Largo to Santiago de los Caballeros
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Highest demand for flights based on searches. 12% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Key Largo to Santiago de los Caballeros

Cheapest flights from Key Largo to Santiago de los Caballeros
Explore the most affordable flight options available from Key Largo to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2025.

This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2110:11 amMIA - STI
Nonstop2h 20mAmerican Airlines
Tue 8/261:31 pmSTI - MIA
Nonstop2h 20mAmerican Airlines
Deal found 8/10$260
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3110:08 amMIA - STI
Nonstop2h 05mAmerican Airlines
Mon 11/34:36 pmSTI - MIA
Nonstop2h 18mAmerican Airlines
Deal found 8/11$262
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2110:11 amMIA - STI
Nonstop2h 20mAmerican Airlines
Sun 8/247:00 amSTI - MIA
Nonstop2h 10mAmerican Airlines
Deal found 8/10$265
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:43 pmMIA - STI
Nonstop2h 05mAmerican Airlines
Sun 8/247:00 amSTI - MIA
Nonstop2h 10mAmerican Airlines
Deal found 8/10$270
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1010:08 amMIA - STI
Nonstop2h 05mAmerican Airlines
Mon 10/131:14 pmSTI - MIA
Nonstop2h 15mAmerican Airlines
Deal found 8/11$340
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2110:08 amMIA - STI
Nonstop2h 05mAmerican Airlines
Mon 11/107:00 amSTI - MIA
Nonstop2h 15mAmerican Airlines
Deal found 8/9$342
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/612:14 pmMIA - STI
Nonstop2h 16mAmerican Airlines
Tue 11/117:00 amSTI - MIA
Nonstop2h 15mAmerican Airlines
Deal found 8/10$343
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/410:17 amMIA - STI
Nonstop2h 10mAmerican Airlines
Sun 10/121:14 pmSTI - MIA
Nonstop2h 15mAmerican Airlines
Deal found 8/12$345
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:17 amMIA - STI
Nonstop2h 10mAmerican Airlines
Mon 9/291:29 pmSTI - MIA
Nonstop2h 16mAmerican Airlines
Deal found 8/9$347
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1910:17 amMIA - STI
Nonstop2h 10mAmerican Airlines
Mon 9/221:29 pmSTI - MIA
Nonstop2h 16mAmerican Airlines
Deal found 8/12$351
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/107:05 amMIA - STI
1 stop12h 01mDelta
Sun 10/126:00 amSTI - MIA
1 stop12h 33mDelta
Deal found 8/12$355

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2025.
Use the filters below to find and compare flights from Key Largo to Santiago de los Caballeros that are best for you.

Fly from

Key Largo

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

Thu 8/21

10:11 am-12:31 pm

Nonstop2h 20m

Santiago de los Caballeros

Tue 8/26

1:31 pm-3:51 pm

Nonstop2h 20m

$260

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

Sun 9/21

10:17 am-12:27 pm

Nonstop2h 10m

Santiago de los Caballeros

Wed 10/8

1:14 pm-3:29 pm

Nonstop2h 15m

$260

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

Mon 9/8

10:17 am-12:27 pm

Nonstop2h 10m

Santiago de los Caballeros

Wed 9/10

1:29 pm-3:45 pm

Nonstop2h 16m

$260

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

Tue 9/9

10:17 am-12:27 pm

Nonstop2h 10m

Santiago de los Caballeros

Tue 9/16

1:29 pm-3:45 pm

Nonstop2h 16m

$260

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

Fri 9/26

10:17 am-12:27 pm

Nonstop2h 10m

Santiago de los Caballeros

Mon 9/29

1:29 pm-3:45 pm

Nonstop2h 16m

$260

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

Thu 8/21

10:11 am-12:31 pm

Nonstop2h 20m

Santiago de los Caballeros

Mon 8/25

7:00 am-9:10 am

Nonstop2h 10m

$260

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

Fri 9/26

10:17 am-12:27 pm

Nonstop2h 10m

Santiago de los Caballeros

Fri 10/3

1:29 pm-3:45 pm

Nonstop2h 16m

$260

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

Sun 8/24

6:30 am-12:16 pm

1 stop5h 46m

$137

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

Fri 8/15

6:30 am-12:51 pm

1 stop6h 21m

$147

MiamiSantiago de los Caballeros

MIA - STI

MIASTI

Miami

Mon 8/18

9:04 pm-12:16 pm

1 stop15h 12m

$159

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/10

Showing 1-10 of 14 results
1
2

Best time to book a flight from Key Largo to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Santiago de los Caballeros

How far ahead should I book a flight from Key Largo to Santiago de los Caballeros?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to Santiago de los Caballeros. Price data was last updated on August 8, 2025.

The best time to book flights from Key Largo to Santiago de los Caballeros is 85 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Key Largo to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Key Largo to Santiago de los Caballeros (average of $347). Flying from Key Largo to Santiago de los Caballeros in July is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to STI?

Find hourly flight availability from Key Largo to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 13, 2025.

When flying from Key Largo to Santiago de los Caballeros, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to Santiago de los Caballeros?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Santiago de los Caballeros. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to Santiago de los Caballeros flight should consider departing on Thursday at noon when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to Santiago de los Caballeros

Explore weekly flight availability from Key Largo to Santiago de los Caballeros. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 13, 2025.

The most flights from KE9 to STI are scheduled on a Tuesday (3 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

How much does it cost to fly round-trip from Key Largo to Santiago de los Caballeros?

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated August 13, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, American Airlines, and JetBlue from Key Largo to Santiago de los Caballeros to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,507 reviews

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Copa Airlines
7.5
Good
1,507 reviews
Copa Airlines
7.5
Good
1,507 reviews

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.5
Good
1,507 reviews

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
JetBlue
7.2
Good
2,915 reviews
Copa Airlines
7.5
Good
1,507 reviews

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Spirit Airlines
6.3
Okay
8,048 reviews
Copa Airlines
7.5
Good
1,507 reviews

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Frontier
5.8
Fair
3,221 reviews
Copa Airlines
7.5
Good
1,507 reviews

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago de los Caballeros from Key Largo?

    Most people fly into Santiago de los Caballeros (STI) if they book a flight to Santiago de los Caballeros from Key Largo. On average, Santiago has 2 inbound flights from Key Largo per day from 5 airlines. Santiago de los Caballeros is conveniently located just 6.8 mi from Santiago de los Caballeros’s city center.

  • How popular is this Key Largo to Santiago de los Caballeros flight route?

    Flights from Key Largo to Santiago de los Caballeros have been viewed 2 times in the past calendar month.

  • What are the cheapest flights from Key Largo to Santiago de los Caballeros?

    On average you can expect to pay $344 for a flight from Key Largo to Santiago de los Caballeros. The cheapest flight overall is $177 while the most popular route, (Miami - Santiago de los Caballeros) is currently priced at $355.

  • Can I find deals for flights from Key Largo to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Key Largo to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Santiago de los Caballeros.

  • Can I find deals for business class flights from Key Largo to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Key Largo to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from Key Largo to Santiago de los Caballeros (average of $347). Flying from Key Largo to Santiago de los Caballeros in July is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Key Largo to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Key Largo to Santiago de los Caballeros

Discover the top 5 airlines that operate flights from Key Largo to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$225Average$305FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$233Average$344FlexibilityNo cancel feeOn-time65%
Copa AirlinesCheapest$303Average$343FlexibilityNo cancel feeOn-time70%
JetBlueCheapest$315Average$486FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$368Average$505FlexibilityNo cancel feeOn-time71%

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