HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago de los Caballeros

$373+ Cheap flights from Denver (DEN) to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — STI
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Denver to Santiago de los Caballeros

Cheapest flights from Denver to Santiago de los Caballeros
Explore the most affordable flight options available from Denver to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Expedia deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:08 pm
DEN
-
STI
1 stop11h 37m
JetBlue
Sat 5/2310:10 pm
STI
-
DEN
1 stop12h 35m
JetBlue
Deal found 1/25$373
This Travelocity deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:59 pm
DEN
-
STI
1 stop25h 00m
JetBlue
Tue 4/143:34 am
STI
-
DEN
1 stop13h 56m
JetBlue
Deal found 1/26$458
This JetBlue deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/611:40 am
DEN
-
STI
1 stop9h 09m
JetBlue
Mon 2/1611:09 pm
STI
-
DEN
1 stop13h 37m
JetBlue
Deal found 1/26$462
This Orbitz deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/311:35 am
DEN
-
STI
1 stop11h 21m
JetBlue
Mon 2/95:10 am
STI
-
DEN
1 stop10h 40m
JetBlue
Deal found 1/26$515
This JetBlue deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:14 pm
DEN
-
STI
1 stop11h 35m
JetBlue
Sun 3/111:06 pm
STI
-
DEN
1 stop15h 04m
JetBlue
Deal found 1/27$562
This Trip.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1911:59 pm
DEN
-
STI
1 stop11h 54m
JetBlue
Sun 3/224:10 am
STI
-
DEN
1 stop11h 50m
JetBlue
Deal found 1/24$568
This Expedia deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:15 pm
DEN
-
STI
1 stop26h 34m
JetBlue
Tue 3/173:10 am
STI
-
DEN
1 stop11h 30m
JetBlue
Deal found 1/25$578
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:59 pm
DEN
-
STI
1 stop17h 21m
Delta
Thu 6/256:15 am
STI
-
DEN
1 stop14h 19m
Delta
Deal found 1/26$579
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:10 am
DEN
-
STI
2 stops15h 44m
Delta
Wed 4/156:00 am
STI
-
DEN
2 stops12h 55m
Delta
Deal found 1/27$587
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:40 am
DEN
-
STI
1 stop15h 10m
Delta
Mon 2/169:59 pm
STI
-
DEN
2 stops18h 36m
Delta
Deal found 1/27$591

Find flight deals from Denver to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$373
(Expedia)

Popular in

December

Cheapest in

October

Average price

$557
Provider with most accurate pricing for Denver Intl-Santiago de los Caballeros flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Santiago de los Caballeros flights.
Search Deals
From Denver Intl to Santiago de los Caballeros
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Denver to Santiago de los Caballeros that are best for you.

Fly from

Denver

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Thu 4/9

11:59 pm-2:59 am

1 stop25h 00m

Santiago de los Caballeros

Tue 4/14

3:34 am-3:30 pm

1 stop13h 56m

$458

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Fri 2/6

1:45 pm-4:32 am

1 stop11h 47m

Santiago de los Caballeros

Mon 2/16

11:09 pm-9:46 am

1 stop13h 37m

$462

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Fri 5/29

11:05 am-2:49 am

1 stop13h 44m

Santiago de los Caballeros

Sun 6/7

11:10 am-9:39 pm

1 stop12h 29m

$562

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Tue 2/24

12:14 pm-2:49 am

1 stop11h 35m

Santiago de los Caballeros

Sun 3/1

11:06 pm-11:10 am

1 stop15h 04m

$562

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Thu 3/19

11:59 pm-1:53 pm

1 stop11h 54m

Santiago de los Caballeros

Sun 3/22

4:10 am-2:00 pm

1 stop11h 50m

$568

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Wed 3/11

11:15 pm-3:49 am

1 stop26h 34m

Santiago de los Caballeros

Tue 3/17

3:10 am-12:40 pm

1 stop11h 30m

$578

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Mon 6/1

11:59 pm-12:05 pm

1 stop10h 06m

Santiago de los Caballeros

Thu 6/25

6:15 am-10:49 pm

1 stop18h 34m

$579

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

  • Most accurate provider: When it comes to deals on Denver-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Santiago de los Caballeros flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santiago de los Caballeros

What is the cheapest month to book a flight from Denver to Santiago de los Caballeros?

Currently, October is the cheapest month in which you can book a flight from Denver to Santiago de los Caballeros (average of $253). Flying from Denver to Santiago de los Caballeros in August is currently the most expensive (average of $522). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated January 27, 2026.
Read through reviews of airlines operating flights from Denver to Santiago de los Caballeros, such as American Airlines and JetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,197 reviews

Overall

7.2

Comfort

7.2

Crew

8.0

Food

6.4

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,197 reviews
American Airlines
7.2
Good
11,197 reviews

Overall

7.2

Comfort

7.2

Crew

8.0

Food

6.4

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
JetBlue
7.2
Good
2,890 reviews
American Airlines
7.2
Good
11,197 reviews

Overall

7.2

Comfort

7.2

Crew

8.0

Food

6.4

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Denver to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Denver to Santiago de los Caballeros?

    Departing from Denver to Santiago de los Caballeros will take you 25h. Denver and Santiago de los Caballeros are separated by a distance of 2461 mi.

  • What are the cheapest airlines flying from Denver to Santiago de los Caballeros round-trip?

    Our cheapest airline available from Denver to Santiago de los Caballeros is JetBlue. Our recent data shows that you can find tickets from as low as $244 on this airline. An additional option worth looking into is American Airlines, starting at $413. Users have found that JetBlue is 58% cheaper than the other options available to this destination.

  • Can I find deals for flights from Denver to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Denver to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santiago de los Caballeros.

  • Can I find deals for business class flights from Denver to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Denver to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Santiago de los Caballeros?

    Currently, October is the cheapest month in which you can book a flight from Denver to Santiago de los Caballeros (average of $253). Flying from Denver to Santiago de los Caballeros in August is currently the most expensive (average of $522). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
Denver to Punta Cana flights
Denver to Santo Domingo flights
Denver to Puerto Plata flights
Colorado Springs to Punta Cana flights
Colorado Springs to Santo Domingo flights
Denver to Nagua flights

Top 2 airlines flying from Denver to Santiago de los Caballeros

Discover the top 2 airlines that operate flights from Denver to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$244Average$549FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$413Average$643FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.