How long is the flight from Denver to Santiago de los Caballeros?

Departing from Denver to Santiago de los Caballeros will take you 11h 57m. Denver and Santiago de los Caballeros are separated by a distance of 2461 mi.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Most accurate provider : When it comes to deals on Denver-Santiago de los Caballeros flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Denver-Santiago de los Caballeros flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Denver-Santiago de los Caballeros flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Denver-Santiago de los Caballeros flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

How can I find direct flights from Denver to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santiago de los Caballeros.

Can I find deals for business class flights from Denver to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Denver to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$174+ Flights from Denver to Santiago de los Caballeros

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Cheap flight deals from Denver to Santiago de los Caballeros

Cheapest flights from Denver to Santiago de los Caballeros
Explore the most affordable flight options available from Denver to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Tue 12/3011:59 pmDEN - STI

2 stops18h 05mAmerican Airlines

Thu 1/156:00 amSTI - DEN

2 stops15h 13mAmerican Airlines

Deal found 12/11

$566

Sat 12/2711:59 pmDEN - STI

1 stop7h 53mMultiple Airlines

Fri 1/27:00 amSTI - DEN

1 stop12h 52mMultiple Airlines

Deal found 12/11

$831

Sat 12/2711:59 pmDEN - STI

2 stops18h 05mAmerican Airlines

Fri 1/26:00 amSTI - DEN

1 stop20h 59mAmerican Airlines

Deal found 12/11

$982

Sun 12/2111:59 pmDEN - STI

2 stops18h 05mAmerican Airlines

Fri 1/26:00 amSTI - DEN

1 stop20h 59mAmerican Airlines

Deal found 12/11

$1,027

Sun 12/2110:02 amDEN - STI

1 stop13h 52mJetBlue

Fri 1/27:00 amSTI - DEN

1 stop12h 52mJetBlue

Deal found 12/10

$1,118

Best flights from Denver to Santiago de los Caballeros
Discover carefully curated flight deals from Denver to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Sat 1/311:40 pmDEN - STI

1 stop11h 57mJetBlue

Mon 2/1610:09 pmSTI - DEN

1 stop14h 29mJetBlue

Deal found 12/10

$397

Tue 12/3011:59 pmDEN - STI

2 stops18h 05mAmerican Airlines

Thu 1/156:00 amSTI - DEN

2 stops15h 13mAmerican Airlines

Deal found 12/11

$566

Sun 1/186:00 amDEN - STI

2 stops11h 34mDelta

Sun 1/259:59 pmSTI - DEN

1 stop15h 58mDelta

Deal found 12/10

$566

Mon 1/261:40 pmDEN - STI

1 stop11h 52mJetBlue

Fri 1/305:05 amSTI - DEN

1 stop10h 40mJetBlue

Deal found 12/10

$422

Sat 3/142:50 pmDEN - STI

1 stop8h 33mJetBlue

Sun 3/2210:01 amSTI - DEN

1 stop15h 03mJetBlue

Deal found 12/10

$428

Sun 1/256:00 amDEN - STI

2 stops11h 34mDelta

Sun 2/19:59 pmSTI - DEN

2 stops18h 38mDelta

Deal found 12/11

$566

Sun 1/1811:35 amDEN - STI

1 stop12h 35mJetBlue

Sun 1/255:10 amSTI - DEN

1 stop10h 35mJetBlue

Deal found 12/10

$508

Tue 3/242:50 pmDEN - STI

1 stop8h 33mJetBlue

Wed 4/810:00 amSTI - DEN

1 stop15h 02mJetBlue

Deal found 12/10

$508

Last-minute flights from Denver to Santiago de los Caballeros
Discover last-minute flight deals from Denver to Santiago de los Caballeros. Data last updated December 12, 2025 and is based on user searches.

Tue 12/3011:59 pmDEN - STI

2 stops18h 05mAmerican Airlines

Thu 1/154:33 pmSTI - DEN

1 stop10h 21mAmerican Airlines

Deal found 12/11

$625

Sun 1/111:40 pmDEN - STI

1 stop11h 52mJetBlue

Thu 1/155:10 amSTI - DEN

1 stop10h 35mJetBlue

Deal found 12/11

$541

Sun 1/116:56 pmDEN - STI

2 stops17h 36mAmerican Airlines

Thu 1/156:00 amSTI - DEN

2 stops11h 14mAmerican Airlines

Deal found 12/11

$570

Sun 1/1811:35 amDEN - STI

1 stop12h 35mJetBlue

Sun 1/255:10 amSTI - DEN

1 stop10h 35mJetBlue

Deal found 12/10

$508

Sun 1/186:00 amDEN - STI

2 stops11h 34mDelta

Sun 1/259:59 pmSTI - DEN

1 stop15h 58mDelta

Deal found 12/10

$566

Sun 1/189:01 amDEN - STI

2 stops9h 45mAmerican Airlines

Sun 1/256:00 amSTI - DEN

2 stops17h 53mAmerican Airlines

Deal found 12/11

$575

Sun 1/2511:35 amDEN - STI

1 stop9h 50mJetBlue

Sun 2/15:10 amSTI - DEN

1 stop10h 35mJetBlue

Deal found 12/11

$549

Mon 1/261:40 pmDEN - STI

1 stop11h 52mJetBlue

Fri 1/305:05 amSTI - DEN

1 stop10h 40mJetBlue

Deal found 12/10

$422

Sat 1/311:40 pmDEN - STI

1 stop11h 57mJetBlue

Mon 2/1610:09 pmSTI - DEN

1 stop14h 29mJetBlue

Deal found 12/10

$397

One-way flights from Denver to Santiago de los Caballeros
Search for one-way flight options from Denver to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Tue 3/311:55 amDEN - STI

1 stop11h 49mJetBlue

Deal found 12/10

$174

Tue 3/37:10 amDEN - STI

2 stops15h 24mDelta

Deal found 12/10

$271

Tue 3/249:40 amDEN - STI

2 stops11h 11mUnited Airlines

Deal found 12/10

$1,572

Find flight deals from Denver to Santiago de los Caballeros

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$397 (Expedia)
One-way from	$174 (Priceline)
Popular in	December
Cheapest in	October
Average price	$946

Provider with most accurate pricing for Denver Intl-Santiago de los Caballeros flight deals.

Search Deals

Provider most trusted by Cheapflights users for Denver Intl-Santiago de los Caballeros flights.

Search Deals

From Denver Intl to Santiago de los Caballeros

Search Deals

One-way flight from Denver Intl to Santiago de los Caballeros

Search Deals

Highest demand for flights based on searches. 15% potential increase in price ($109 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($33 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sat 1/31

1:40 pm-4:37 am

1 stop11h 57m

Santiago de los Caballeros

Mon 2/16

10:09 pm-9:38 am

1 stop14h 29m

$397

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Mon 1/26

1:40 pm-4:32 am

1 stop11h 52m

Santiago de los Caballeros

Fri 1/30

5:05 am-12:45 pm

1 stop10h 40m

$422

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sat 3/14

2:50 pm-1:23 am

1 stop8h 33m

Santiago de los Caballeros

Sun 3/22

10:01 am-11:04 pm

1 stop15h 03m

$428

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sun 1/18

11:35 am-3:10 am

1 stop12h 35m

Santiago de los Caballeros

Sun 1/25

5:10 am-12:45 pm

1 stop10h 35m

$508

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Tue 3/24

2:50 pm-1:23 am

1 stop8h 33m

Santiago de los Caballeros

Wed 4/8

10:00 am-11:02 pm

1 stop15h 02m

$508

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Tue 12/30

11:59 pm-9:04 pm

2 stops18h 05m

Santiago de los Caballeros

Thu 1/15

6:00 am-6:13 pm

2 stops15h 13m

$566

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sun 1/18

6:00 am-8:34 pm

2 stops11h 34m

Santiago de los Caballeros

Sun 1/25

9:59 pm-10:57 am

1 stop15h 58m

$566

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sun 1/25

6:00 am-8:34 pm

2 stops11h 34m

Santiago de los Caballeros

Sun 2/1

9:59 pm-1:37 pm

2 stops18h 38m

$566

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Tue 3/3

11:55 am-2:44 am

1 stop11h 49m

$174

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Tue 3/24

2:50 pm-1:23 am

1 stop8h 33m

$174

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 12 results

Compare providers for flights from Denver to Santiago de los Caballeros

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santiago de los Caballeros in December.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Denver-Santiago de los Caballeros flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Denver-Santiago de los Caballeros flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Denver-Santiago de los Caballeros flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Denver-Santiago de los Caballeros flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Denver with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santiago de los Caballeros

What is the cheapest month to book a flight from Denver to Santiago de los Caballeros?

Currently, October is the cheapest month in which you can book a flight from Denver to Santiago de los Caballeros (average of $253). Flying from Denver to Santiago de los Caballeros in August is currently the most expensive (average of $522). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to STI?

A simple way to save on the total cost of your ticket is to fly from Denver to Santiago de los Caballeros in the morning. If you’re flexible enough to do this you can expect to save up to 9% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Santiago de los Caballeros

Read through reviews of airlines operating flights from Denver to Santiago de los Caballeros, such as American Airlines and JetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

11,048 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

American Airlines

7.2

Good

11,048 reviews

American Airlines

7.2

Good

11,048 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

JetBlue

7.2

Good

2,898 reviews

American Airlines

7.2

Good

11,048 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

How long is the flight from Denver to Santiago de los Caballeros?
Departing from Denver to Santiago de los Caballeros will take you 11h 57m. Denver and Santiago de los Caballeros are separated by a distance of 2461 mi.
What are the cheapest airlines flying from Denver to Santiago de los Caballeros round-trip?
Our cheapest airline available from Denver to Santiago de los Caballeros is JetBlue. Our recent data shows that you can find tickets from as low as $244 on this airline. An additional option worth looking into is American Airlines, starting at $413. Users have found that JetBlue is 59% cheaper than the other options available to this destination.
Can I find deals for flights from Denver to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Denver to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Denver to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santiago de los Caballeros.
Can I find deals for business class flights from Denver to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Denver to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Denver to Santiago de los Caballeros?
Currently, October is the cheapest month in which you can book a flight from Denver to Santiago de los Caballeros (average of $253). Flying from Denver to Santiago de los Caballeros in August is currently the most expensive (average of $522). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Denver to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
JetBlue	Cheapest$296	Average$531	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$413	Average$648	FlexibilityNo cancel fee	On-time71%

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$174+ Cheap flights from Denver (DEN) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Denver to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

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Cheap flight deals from Denver to Santiago de los Caballeros

Cheapest flights from Denver to Santiago de los CaballerosExplore the most affordable flight options available from Denver to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Denver to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Denver to Santiago de los Caballeros

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to Santiago de los Caballeros that are best for you.

Compare providers for flights from Denver to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santiago de los Caballeros in December.

Best time to book a flight from Denver to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Denver with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santiago de los Caballeros

What is the cheapest month to book a flight from Denver to Santiago de los Caballeros?

What is the cheapest time of day to fly from DEN to STI?

Reviews of airlines servicing Santiago de los Caballeros

Read through reviews of airlines operating flights from Denver to Santiago de los Caballeros, such as American Airlines and JetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Denver to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Denver to Santiago de los Caballeros?

What are the cheapest airlines flying from Denver to Santiago de los Caballeros round-trip?

Can I find deals for flights from Denver to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Denver to Santiago de los Caballeros?

Can I find deals for business class flights from Denver to Santiago de los Caballeros?

What is the cheapest month to book a flight from Denver to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Denver to Santiago de los Caballeros

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Cheapest flights from Denver to Santiago de los Caballeros
Explore the most affordable flight options available from Denver to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.