HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago de los Caballeros

$485+ Cheap flights from Denver (DEN) to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — STI
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Denver to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$485
(JetBlue)

Popular in

December

Cheapest in

February

Average price

$531
From Denver Intl to Santiago de los Caballeros
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($190 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Denver to Santiago de los Caballeros

Cheapest flights from Denver to Santiago de los Caballeros
Explore the most affordable flight options available from Denver to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/111:25 amDEN - STI
1 stop12h 56mJetBlue
Mon 10/69:55 amSTI - DEN
1 stop15h 09mJetBlue
Deal found 9/10$523
This SmartFares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:46 amDEN - STI
1 stop15h 12mJetBlue
Thu 12/111:00 pmSTI - DEN
1 stop12h 04mJetBlue
Deal found 9/11$530
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1011:49 amDEN - STI
2 stops17h 28mJetBlue
Sun 12/1410:46 amSTI - DEN
1 stop14h 18mJetBlue
Deal found 9/11$538
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:10 amDEN - STI
1 stop9h 26mDelta
Tue 12/98:57 pmSTI - DEN
1 stop16h 52mDelta
Deal found 9/11$557
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2712:42 pmDEN - STI
1 stop9h 42mDelta
Fri 10/316:00 amSTI - DEN
1 stop17h 41mDelta
Deal found 9/11$563
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2312:20 pmDEN - STI
1 stop9h 39mDelta
Wed 11/269:01 pmSTI - DEN
1 stop15h 58mDelta
Deal found 9/11$565
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/278:05 amDEN - STI
1 stop13h 54mDelta
Thu 12/116:35 amSTI - DEN
2 stops13h 50mDelta
Deal found 9/11$566
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2412:17 amDEN - STI
1 stop19h 39mAmerican Airlines
Tue 12/96:04 amSTI - DEN
1 stop18h 25mAmerican Airlines
Deal found 9/11$569
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:59 pmDEN - STI
2 stops17h 34mAmerican Airlines
Sun 12/146:04 amSTI - DEN
2 stops15h 57mAmerican Airlines
Deal found 9/11$571

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Denver to Santiago de los Caballeros that are best for you.

Fly from

Denver

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sun 3/1

10:44 pm-12:07 pm

1 stop10h 23m

Santiago de los Caballeros

Thu 3/5

1:35 pm-9:49 pm

1 stop11h 14m

$485

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Wed 10/1

11:25 am-2:21 am

1 stop12h 56m

Santiago de los Caballeros

Mon 10/6

9:55 am-11:04 pm

1 stop15h 09m

$523

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Mon 11/24

12:17 am-3:32 pm

1 stop12h 15m

Santiago de los Caballeros

Tue 12/9

4:32 pm-11:03 pm

1 stop9h 31m

$557

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Tue 11/25

7:10 am-12:59 am

1 stop14h 49m

Santiago de los Caballeros

Tue 12/9

6:35 am-11:46 pm

1 stop20h 11m

$557

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Mon 10/27

7:10 am-12:24 am

1 stop15h 14m

Santiago de los Caballeros

Fri 10/31

6:00 am-9:41 pm

1 stop17h 41m

$563

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Denver to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santiago de los Caballeros

What is the cheapest month to book a flight from Denver to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Denver to Santiago de los Caballeros (average of $347). Flying from Denver to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to STI?

Find hourly flight availability from Denver to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Denver to Santiago de los Caballeros in the morning. If you’re flexible enough to do this you can expect to save up to 10% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Denver to Santiago de los Caballeros, such as Delta, American Airlines, and JetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
JetBlue
7.2
Good
2,913 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Denver to Santiago de los Caballeros?

    Departing from Denver to Santiago de los Caballeros will take you 10h 23m. Denver and Santiago de los Caballeros are separated by a distance of 2461 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Denver to Santiago de los Caballeros round-trip?

    Our cheapest airline available from Denver to Santiago de los Caballeros is JetBlue. Our recent data shows that you can find tickets from as low as $296 on this airline. Additional options worth looking into are American Airlines and Delta, starting at $495 and $498 round-trip. Users have found that JetBlue is 55% cheaper than the other options available to this destination.

  • Can I find deals for flights from Denver to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Denver to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santiago de los Caballeros.

  • Can I find deals for business class flights from Denver to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Denver to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from Denver to Santiago de los Caballeros (average of $347). Flying from Denver to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
Denver to Punta Cana flights
Denver to Santo Domingo flights
Denver to Puerto Plata flights
Colorado Springs to Punta Cana flights
Colorado Springs to Santo Domingo flights
Denver to Nagua flights

Top 3 airlines flying from Denver to Santiago de los Caballeros

Discover the top 3 airlines that operate flights from Denver to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$296Average$555FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$495Average$685FlexibilityNo cancel feeOn-time71%
DeltaCheapest$498Average$582FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.