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$283+ Cheap flights from Tampa (TPA) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — SCL
Aug 16 — Aug 231
Sat 8/16
Sat 8/23
1 adult, Economy
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Cheapflights Tip: The best prices from Tampa to Santiago Arturo Merino Benitez are usually found in August or September, booked 6 days in advance, depart on a Wednesday or Sunday and return on a Monday

Cheap flight deals from Tampa to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 11, 2025.

Round-trip from

$501
(Copa Airlines)

One-way from

$283
(Copa Airlines)

Popular in

January

Cheapest in

August

Average price

$613
From Tampa to Santiago Arturo Merino Benitez
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One-way flight from Tampa to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 14% potential increase in price ($126 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Tampa to Santiago

Cheapest flights from Tampa to Santiago
Explore the most affordable flight options available from Tampa to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

This Copa Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/173:16 pmTPA - SCL
1 stop11h 26mCopa Airlines
Tue 9/231:13 amSCL - TPA
1 stop13h 14mCopa Airlines
Deal found 8/9$501
This FlightHub deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1712:31 pmTPA - SCL
1 stop17h 29mLATAM Airlines
Wed 9/248:15 amSCL - TPA
2 stops16h 40mLATAM Airlines
Deal found 8/10$507
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/128:05 pmTPA - SCL
2 stops17h 55mDelta
Sun 9/2111:55 pmSCL - TPA
1 stop19h 05mDelta
Deal found 8/9$514
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/287:40 pmTPA - SCL
1 stop11h 15mAmerican Airlines
Mon 9/19:55 pmSCL - TPA
2 stops18h 19mAmerican Airlines
Deal found 8/10$518
This Copa Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/123:16 pmTPA - SCL
1 stop11h 26mCopa Airlines
Sat 9/203:26 amSCL - TPA
1 stop11h 01mCopa Airlines
Deal found 8/10$521
This Copa Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/223:16 pmTPA - SCL
1 stop11h 30mCopa Airlines
Sat 9/61:13 amSCL - TPA
1 stop15h 59mCopa Airlines
Deal found 8/11$522
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/127:40 pmTPA - SCL
1 stop11h 15mAmerican Airlines
Wed 8/209:55 pmSCL - TPA
1 stop16h 49mAmerican Airlines
Deal found 8/9$562
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/143:16 pmTPA - SCL
1 stop13h 46mMultiple Airlines
Sat 8/1611:55 pmSCL - TPA
1 stop12h 20mMultiple Airlines
Deal found 8/10$589
This Copa Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/123:16 pmTPA - SCL
1 stop13h 46mCopa Airlines
Tue 8/192:26 amSCL - TPA
1 stop13h 46mCopa Airlines
Deal found 8/11$598

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tampa to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
Use the filters below to find and compare flights from Tampa to Santiago that are best for you.

Fly from

Tampa

Fly to

Santiago

Route

Depart

Return

Price

TampaSantiago

TPA - SCL

TPASCL

Tampa

Wed 9/17

3:16 pm-3:42 am

1 stop11h 26m

Santiago Arturo Merino Benitez

Tue 9/23

1:13 am-1:27 pm

1 stop13h 14m

$501

TampaSantiago

TPA - SCL

TPASCL

Tampa

Wed 9/17

12:31 pm-7:00 am

1 stop17h 29m

Santiago Arturo Merino Benitez

Wed 9/24

8:15 am-11:55 pm

2 stops16h 40m

$507

TampaSantiago

TPA - SCL

TPASCL

Tampa

Fri 9/12

11:00 am-7:50 am

1 stop19h 50m

Santiago Arturo Merino Benitez

Sun 9/21

11:55 pm-10:20 pm

1 stop23h 25m

$514

TampaSantiago

TPA - SCL

TPASCL

Tampa

Thu 8/28

7:40 pm-6:55 am

1 stop11h 15m

Santiago Arturo Merino Benitez

Mon 9/1

9:55 pm-4:14 pm

2 stops18h 19m

$518

TampaSantiago

TPA - SCL

TPASCL

Tampa

Fri 9/12

3:16 pm-3:42 am

1 stop11h 26m

Santiago Arturo Merino Benitez

Sat 9/20

1:24 am-4:12 pm

1 stop15h 48m

$521

TampaSantiago

TPA - SCL

TPASCL

Tampa

Fri 8/22

3:16 pm-2:46 am

1 stop11h 30m

Santiago Arturo Merino Benitez

Sat 9/6

1:13 am-4:12 pm

1 stop15h 59m

$522

TampaSantiago

TPA - SCL

TPASCL

Tampa

Fri 8/22

11:14 am-4:45 am

2 stops17h 31m

Santiago Arturo Merino Benitez

Sun 9/7

11:55 pm-6:53 pm

2 stops19h 58m

$566

TampaSantiago

TPA - SCL

TPASCL

Tampa

Wed 11/26

12:18 pm-6:35 am

2 stops16h 17m

Santiago Arturo Merino Benitez

Sat 12/6

11:15 pm-9:53 am

1 stop12h 38m

$602

TampaSantiago

TPA - SCL

TPASCL

Tampa

Mon 9/8

3:16 pm-3:42 am

1 stop11h 26m

Santiago Arturo Merino Benitez

Sun 9/14

3:26 am-1:27 pm

1 stop11h 01m

$621

TampaSantiago

TPA - SCL

TPASCL

Tampa

Mon 9/8

7:58 pm-1:20 pm

2 stops16h 22m

Santiago Arturo Merino Benitez

Sun 9/14

12:55 am-12:15 pm

1 stop12h 20m

$666

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/9

Showing 1-10 of 17 results
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Best time to book a flight from Tampa to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Tampa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to Santiago

How far ahead should I book a flight from Tampa to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Tampa to Santiago. Price data was last updated on August 8, 2025.

Booking 6 days in advance of your planned departure date is, on average, the best time to get cheap flights from Tampa to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Tampa to Santiago?

Currently, April is the cheapest month in which you can book a flight from Tampa to Santiago (average of $752). Flying from Tampa to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TPA to SCL?

Find hourly flight availability from Tampa to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 11, 2025.

One of the essential ways to save on airfare from Tampa to Santiago is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 26% on airfare.

What’s the top layover airport for flights from Tampa to Santiago?

Share of 1-stop round-trip flights from Tampa to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.

Panama City (PTY) – chosen by Cheapflights users on 67% of 1-stop itineraries from Tampa to Santiago on Cheapflights.

What’s the cheapest layover airport for flights from Tampa to Santiago?

Average round-trip fare for 1-stop flights from Tampa to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Atlanta (ATL) is the most affordable 1-stop option, with an average round-trip price of $652.

What’s the fastest layover option from Tampa to Santiago?

Shortest average travel time for 1-stop one-way flights from Tampa to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 11h 27m.

Which airport typically offers the quickest layover for flights from Tampa to Santiago?

Average layover duration for 1-stop one-way flights from Tampa to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 10m.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated August 11, 2025.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and Copa Airlines from Tampa to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
LATAM Airlines
7.5
Good
1,837 reviews
Delta
8.0
Very good
7,979 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Copa Airlines
7.5
Good
1,505 reviews
Delta
8.0
Very good
7,979 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,920 reviews
Delta
8.0
Very good
7,979 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Tampa to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Tampa to Santiago round-trip?

    Flying on Copa Airlines is currently your cheapest option to Santiago, with prices starting at $501. Additional round-trip tickets that might be worth considering are offered by LATAM Airlines and Delta, with the lowest prices starting at $507 and $514, respectively. Users have found that Copa Airlines is 35% cheaper than the other options available to this destination.

  • Can I find deals for flights from Tampa to Santiago that include hotel bookings?

    Yes. In addition to deals on Tampa to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tampa to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tampa to Santiago.

  • Can I find deals for business class flights from Tampa to Santiago?

    Yes. Cheapflights offers flight deals from Tampa to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Tampa to Santiago (average of $752). Flying from Tampa to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from Tampa to Santiago

Discover the top 5 airlines that operate flights from Tampa to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$405Average$405FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$473Average$853FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$480Average$691FlexibilityNo cancel feeOn-time70%
DeltaCheapest$513Average$706FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$513Average$846FlexibilityNo cancel feeOn-time71%

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