$223+ Cheap flights from Tampa (TPA) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — SCL
Mar 13 — Mar 201
1 adult, Economy
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Cheapest flights from Tampa to SantiagoExplore the most affordable flight options available from Tampa to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.
Explore the most affordable flight options available from Tampa to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.
This Avianca deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:45 pm
TPA
- SCL
1 stop13h 00m
Avianca
Fri 8/1412:30 am
SCL
- TPA
1 stop13h 50m
Avianca
Deal found 2/9![Avianca logo]()
$501
This Copa Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:27 pm
TPA
- SCL
1 stop10h 49m
Copa Airlines
Tue 9/1512:22 pm
SCL
- TPA
1 stop11h 43m
Copa Airlines
Deal found 2/9![Copa Airlines logo]()
$503
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:33 pm
TPA
- SCL
1 stop14h 32m
American Airlines
Wed 3/259:20 pm
SCL
- TPA
1 stop12h 50m
American Airlines
Deal found 2/8![American Airlines logo]()
$511
This LATAM Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:50 pm
TPA
- SCL
2 stops19h 15m
LATAM Airlines
Sun 5/174:30 pm
SCL
- TPA
2 stops26h 11m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$515
This Avianca deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:45 pm
TPA
- SCL
1 stop13h 00m
Avianca
Tue 5/2612:30 am
SCL
- TPA
1 stop13h 50m
Avianca
Deal found 2/9![Avianca logo]()
$517
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:25 pm
TPA
- SCL
2 stops18h 25m
United Airlines
Tue 3/179:45 pm
SCL
- TPA
2 stops20h 19m
United Airlines
Deal found 2/9![United Airlines logo]()
$520
This Copa Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:23 am
TPA
- SCL
1 stop17h 20m
Copa Airlines
Fri 5/1511:17 am
SCL
- TPA
1 stop11h 48m
Copa Airlines
Deal found 2/10![Copa Airlines logo]()
$521
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:32 pm
TPA
- SCL
2 stops15h 18m
American Airlines
Sat 8/158:30 pm
SCL
- TPA
1 stop12h 54m
American Airlines
Deal found 2/11![American Airlines logo]()
$530
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/159:00 am
TPA
- SCL
1 stop21h 50m
United Airlines
Wed 3/410:45 pm
SCL
- TPA
2 stops49h 14m
United Airlines
Deal found 2/9![United Airlines logo]()
$535
This Expedia deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/51:05 pm
TPA
- SCL
1 stop18h 10m
LATAM Airlines
Mon 4/134:30 pm
SCL
- TPA
2 stops31h 54m
LATAM Airlines
Deal found 2/11![LATAM Airlines logo]()
$540
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:00 am
TPA
- SCL
3 stops45h 50m
United Airlines
Wed 3/189:45 pm
SCL
- TPA
1 stop13h 49m
United Airlines
Deal found 2/9![United Airlines logo]()
$541
Best flights from Tampa to SantiagoDiscover carefully curated flight deals from Tampa to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 11, 2026.
Discover carefully curated flight deals from Tampa to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 11, 2026.
This Avianca deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:45 pm
TPA
- SCL
1 stop13h 00m
Avianca
Fri 8/1412:30 am
SCL
- TPA
1 stop13h 50m
Avianca
Deal found 2/8![Avianca logo]()
$501
This Copa Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/94:51 am
TPA
- SCL
1 stop17h 58m
Copa Airlines
Fri 3/1312:28 pm
SCL
- TPA
1 stop11h 37m
Copa Airlines
Deal found 2/10![Copa Airlines logo]()
$503
This LATAM Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:50 pm
TPA
- SCL
1 stop12h 25m
LATAM Airlines
Sun 5/178:40 pm
SCL
- TPA
1 stop13h 16m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$515
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/109:30 am
TPA
- SCL
1 stop21h 20m
United Airlines
Tue 3/179:45 pm
SCL
- TPA
1 stop13h 49m
United Airlines
Deal found 2/9![United Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:05 pm
TPA
- SCL
1 stop15h 45m
American Airlines
Sat 8/158:30 pm
SCL
- TPA
1 stop11h 35m
American Airlines
Deal found 2/10![American Airlines logo]()
$515
This Avianca deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/13:45 pm
TPA
- SCL
1 stop13h 00m
Avianca
Fri 8/712:30 am
SCL
- TPA
1 stop13h 50m
Avianca
Deal found 2/9![Avianca logo]()
$501
This Copa Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:23 am
TPA
- SCL
1 stop18h 03m
Copa Airlines
Fri 5/1511:17 am
SCL
- TPA
1 stop11h 48m
Copa Airlines
Deal found 2/7![Copa Airlines logo]()
$503
This KAYAK deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:55 pm
TPA
- SCL
2 stops22h 10m
LATAM Airlines
Wed 5/611:05 pm
SCL
- TPA
2 stops19h 36m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$515
This deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:05 pm
TPA
- SCL
1 stop13h 45m
United Airlines
Wed 3/259:45 pm
SCL
- TPA
1 stop13h 49m
United Airlines
Deal found 2/9![United Airlines logo]()
$515
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:26 pm
TPA
- SCL
1 stop18h 49m
LATAM Airlines
Mon 4/135:40 am
SCL
- TPA
2 stops27h 12m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$515
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:16 am
TPA
- SCL
1 stop21h 39m
LATAM Airlines
Wed 3/186:40 pm
SCL
- TPA
2 stops18h 55m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$515
Last-minute flights from Tampa to SantiagoDiscover last-minute flight deals from Tampa to Santiago. Data last updated February 11, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to Santiago. Data last updated February 11, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/159:00 am
TPA
- SCL
1 stop21h 50m
United Airlines
Wed 3/410:45 pm
SCL
- TPA
2 stops49h 14m
United Airlines
Deal found 2/9![United Airlines logo]()
$535
This Gurufare deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:38 pm
TPA
- SCL
1 stop17h 02m
LATAM Airlines
Mon 3/236:40 pm
SCL
- TPA
2 stops20h 12m
LATAM Airlines
Deal found 2/8![LATAM Airlines logo]()
$527
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:21 am
TPA
- SCL
1 stop18h 44m
American Airlines
Sat 3/79:15 pm
SCL
- TPA
2 stops16h 46m
American Airlines
Deal found 2/9![American Airlines logo]()
$530
This Copa Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/94:51 am
TPA
- SCL
1 stop17h 58m
Copa Airlines
Fri 3/1312:28 pm
SCL
- TPA
1 stop11h 37m
Copa Airlines
Deal found 2/10![Copa Airlines logo]()
$503
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:25 pm
TPA
- SCL
2 stops18h 25m
United Airlines
Tue 3/179:45 pm
SCL
- TPA
2 stops20h 19m
United Airlines
Deal found 2/9![United Airlines logo]()
$520
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:40 am
TPA
- SCL
1 stop19h 10m
United Airlines
Wed 3/189:45 pm
SCL
- TPA
1 stop20h 49m
United Airlines
Deal found 2/9![United Airlines logo]()
$515
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:00 am
TPA
- SCL
1 stop23h 50m
United Airlines
Thu 3/199:45 pm
SCL
- TPA
1 stop13h 49m
United Airlines
Deal found 2/10![United Airlines logo]()
$573
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:36 pm
TPA
- SCL
2 stops36h 14m
United Airlines
Tue 3/179:45 pm
SCL
- TPA
2 stops20h 19m
United Airlines
Deal found 2/8![United Airlines logo]()
$586
This Expedia deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/183:55 pm
TPA
- SCL
1 stop31h 35m
Multiple Airlines
Sat 3/214:20 pm
SCL
- TPA
2 stops42h 35m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$554
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:33 pm
TPA
- SCL
1 stop14h 32m
American Airlines
Wed 3/259:20 pm
SCL
- TPA
1 stop12h 50m
American Airlines
Deal found 2/8![American Airlines logo]()
$511
One-way flights from Tampa to SantiagoSearch for one-way flight options from Tampa to Santiago. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.
Search for one-way flight options from Tampa to Santiago. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:44 am
TPA
- SCL
3 stops44h 46m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$223
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/151:05 pm
TPA
- SCL
1 stop17h 35m
Delta
Deal found 2/8![Delta logo]()
$238
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:45 pm
TPA
- SCL
1 stop11h 20m
American Airlines
Deal found 2/10![American Airlines logo]()
$240
This Trip.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/223:45 pm
TPA
- SCL
1 stop13h 00m
Avianca
Deal found 2/10![Avianca logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/155:30 am
TPA
- SCL
3 stops56h 10m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:57 am
TPA
- SCL
2 stops36h 29m
United Airlines
Deal found 2/10![United Airlines logo]()
$320
This Travelocity deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:56 pm
TPA
- SCL
2 stops41h 39m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/154:49 pm
TPA
- SCL
2 stops15h 16m
American Airlines
Deal found 2/11![American Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2512:30 pm
TPA
- SCL
2 stops42h 20m
United Airlines
Deal found 2/9![United Airlines logo]()
$413
Find flight deals from Tampa to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $501 (Avianca) |
One-way from | $223 (Kiwi.com) |
Popular in | July |
Cheapest in | October |
Average price | $828 |
Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Tampa to Santiago that are best for you.
Fly from
Tampa
Fly to
Santiago
Route
Depart
Return
Price
TampaSantiago
TPA - SCL
TPASCL
Tampa
Fri 8/7
3:45 pm-4:45 am
1 stop13h 00m
Santiago Arturo Merino Benitez
Fri 8/14
12:30 am-2:20 pm
1 stop13h 50m
$501
TampaSantiago
TPA - SCL
TPASCL
Tampa
Sat 8/1
3:45 pm-4:45 am
1 stop13h 00m
Santiago Arturo Merino Benitez
Fri 8/7
12:30 am-2:20 pm
1 stop13h 50m
$501
TampaSantiago
TPA - SCL
TPASCL
Tampa
Mon 3/9
4:51 am-11:49 pm
1 stop17h 58m
Santiago Arturo Merino Benitez
Fri 3/13
12:28 pm-11:05 pm
1 stop11h 37m
$503
TampaSantiago
TPA - SCL
TPASCL
Tampa
Fri 5/1
5:23 am-11:26 pm
1 stop18h 03m
Santiago Arturo Merino Benitez
Fri 5/15
11:17 am-11:05 pm
1 stop11h 48m
$503
TampaSantiago
TPA - SCL
TPASCL
Tampa
Wed 5/13
6:50 pm-7:15 am
1 stop12h 25m
Santiago Arturo Merino Benitez
Sun 5/17
8:40 pm-9:56 am
1 stop13h 16m
$515
TampaSantiago
TPA - SCL
TPASCL
Tampa
Tue 3/10
9:30 am-7:50 am
1 stop21h 20m
Santiago Arturo Merino Benitez
Tue 3/17
9:45 pm-10:34 am
1 stop13h 49m
$515
TampaSantiago
TPA - SCL
TPASCL
Tampa
Fri 8/7
3:05 pm-6:50 am
1 stop15h 45m
Santiago Arturo Merino Benitez
Sat 8/15
8:30 pm-8:05 am
1 stop11h 35m
$515
TampaSantiago
TPA - SCL
TPASCL
Tampa
Thu 4/30
3:55 pm-2:05 pm
2 stops22h 10m
Santiago Arturo Merino Benitez
Wed 5/6
11:05 pm-6:41 pm
2 stops19h 36m
$515
TampaSantiago
TPA - SCL
TPASCL
Tampa
Mon 3/23
5:05 pm-7:50 am
1 stop13h 45m
Santiago Arturo Merino Benitez
Wed 3/25
9:45 pm-10:34 am
1 stop13h 49m
$515
TampaSantiago
TPA - SCL
TPASCL
Tampa
Wed 4/1
12:26 pm-8:15 am
1 stop18h 49m
Santiago Arturo Merino Benitez
Mon 4/13
5:40 am-8:52 am
2 stops27h 12m
$515
Showing 1-10 of 19 results
Compare providers for flights from Tampa to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tampa to Santiago in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Tampa-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tampa-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tampa-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Tampa-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tampa-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Tampa to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Tampa with our price prediction graph.
TPA-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Tampa to Santiago
Prices
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What is the cheapest month to book a flight from Tampa to Santiago?
Currently, November is the cheapest month in which you can book a flight from Tampa to Santiago (average of $245). Flying from Tampa to Santiago in December is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Tampa to Santiago?
What’s the top layover airport for flights from Tampa to Santiago?
Share of 1-stop round-trip flights from Tampa to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 50% of 1-stop itineraries from Tampa to Santiago on Cheapflights.
What’s the cheapest layover airport for flights from Tampa to Santiago?
Average round-trip fare for 1-stop flights from Tampa to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Houston (IAH) is the most affordable 1-stop option, with an average round-trip price of $494.
What’s the fastest layover option from Tampa to Santiago?
Shortest average travel time for 1-stop one-way flights from Tampa to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 11h 27m.
Which airport typically offers the quickest layover for flights from Tampa to Santiago?
Average layover duration for 1-stop one-way flights from Tampa to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 10m.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated February 11, 2026.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and Copa Airlines from Tampa to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.9
Overall
7.9
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Comfort
7.9
Overall
7.9
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Comfort
7.9
Overall
7.9
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Comfort
7.9
Overall
7.9
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Comfort
7.9
Overall
7.9
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Comfort
7.9
Overall
7.9
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Tampa to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Tampa to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Tampa to Santiago by cabin class
Find flights from Tampa to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Tampa and Santiago flights
Browse other Tampa and Santiago flight options. Last updated on February 11, 2026.
Other flights from Tampa
Browse through other flights departing from Tampa. Flights are based on user searches made on Cheapflights and were last updated on February 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 11, 2026.
Top 5 airlines flying from Tampa to Santiago
Discover the top 5 airlines that operate flights from Tampa to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$298 | Average$571 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$304 | Average$614 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$381 | Average$642 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$473 | Average$574 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$493 | Average$695 | FlexibilityNo cancel fee | On-time71% |