$230+ Cheap flights from Santa Cruz de la Sierra (VVI) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/22. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SCL
Jun 10 — Jun 171
Round-trip
1 adult, Economy
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Find cheap flights from Santa Cruz de la Sierra to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez are usually found in September or October, booked 53 days in advance, depart on a Wednesday or Monday and return on a Monday
Cheap flight deals from Santa Cruz de la Sierra to Santiago
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santa Cruz de la Sierra to SantiagoExplore the most affordable flight options available from Santa Cruz de la Sierra to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
Explore the most affordable flight options available from Santa Cruz de la Sierra to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
This Trip.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Sat 8/2212:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/8![BoA logo]()
$379
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Mon 8/3112:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/11![BoA logo]()
$402
This CheapOair deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Sat 6/2712:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/8![BoA logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Mon 6/1512:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/10![BoA logo]()
$422
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Sat 7/1812:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/11![BoA logo]()
$424
This CheapOair deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Sat 7/412:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/10![BoA logo]()
$444
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:00 am
VVI
- SCL
Nonstop3h 15m
Multiple Airlines
Mon 8/312:35 pm
SCL
- VVI
1 stop10h 35m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:00 am
VVI
- SCL
1 stop21h 11m
Multiple Airlines
Mon 6/1512:10 pm
SCL
- VVI
Nonstop3h 15m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$455
This CheapOair deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:00 am
VVI
- SCL
Nonstop3h 15m
Multiple Airlines
Sat 7/45:32 am
SCL
- VVI
1 stop4h 57m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$462
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/192:20 am
VVI
- SCL
1 stop15h 05m
Multiple Airlines
Sat 6/2712:10 pm
SCL
- VVI
Nonstop3h 15m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$464
Best flights from Santa Cruz de la Sierra to SantiagoDiscover carefully curated flight deals from Santa Cruz de la Sierra to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
Discover carefully curated flight deals from Santa Cruz de la Sierra to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Mon 8/3112:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/11![BoA logo]()
$402
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:00 am
VVI
- SCL
Nonstop3h 15m
Multiple Airlines
Mon 8/312:35 pm
SCL
- VVI
1 stop10h 35m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$448
This CheapOair deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Sat 7/1812:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/10![BoA logo]()
$424
This CheapOair deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:00 am
VVI
- SCL
Nonstop2h 15m
Multiple Airlines
Tue 11/37:45 pm
SCL
- VVI
1 stop9h 50m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$524
This CheapOair deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:15 am
VVI
- SCL
Nonstop2h 09m
Multiple Airlines
Sun 9/278:50 pm
SCL
- VVI
1 stop29h 20m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$536
Last-minute flights from Santa Cruz de la Sierra to SantiagoDiscover last-minute flight deals from Santa Cruz de la Sierra to Santiago. Data last updated May 11, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Cruz de la Sierra to Santiago. Data last updated May 11, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:15 am
VVI
- SCL
Nonstop3h 09m
Multiple Airlines
Sun 6/78:50 pm
SCL
- VVI
1 stop28h 20m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$557
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Mon 6/1512:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/10![BoA logo]()
$422
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:00 am
VVI
- SCL
1 stop21h 11m
Multiple Airlines
Mon 6/1512:10 pm
SCL
- VVI
Nonstop3h 15m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$455
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/192:20 am
VVI
- SCL
1 stop15h 05m
Multiple Airlines
Sat 6/2712:10 pm
SCL
- VVI
Nonstop3h 15m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$464
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Sat 6/2712:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/11![BoA logo]()
$402
This CheapOair deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Sat 7/412:10 pm
SCL
- VVI
Nonstop3h 15m
BoA
Deal found 5/10![BoA logo]()
$444
This CheapOair deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:00 am
VVI
- SCL
Nonstop3h 15m
Multiple Airlines
Sat 7/45:32 am
SCL
- VVI
1 stop4h 57m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$462
One-way flights from Santa Cruz de la Sierra to SantiagoSearch for one-way flight options from Santa Cruz de la Sierra to Santiago. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
Search for one-way flight options from Santa Cruz de la Sierra to Santiago. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
This SmartFares deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Deal found 5/6![BoA logo]()
$230
This CheapOair deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Deal found 5/10![BoA logo]()
$247
This Mytrip deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Deal found 5/11![BoA logo]()
$251
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:00 am
VVI
- SCL
Nonstop3h 15m
BoA
Deal found 5/11![BoA logo]()
$269
This FlightHub deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:20 am
VVI
- SCL
1 stop15h 00m
Aerolineas Argentinas
Deal found 5/10![Aerolineas Argentinas logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:00 am
VVI
- SCL
1 stop13h 36m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$322
This Justfly.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:25 am
VVI
- SCL
1 stop8h 40m
LATAM Airlines
Deal found 5/6![LATAM Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:00 am
VVI
- SCL
1 stop21h 11m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$338
This FlightHub deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:25 am
VVI
- SCL
1 stop8h 40m
LATAM Airlines
Deal found 5/6![LATAM Airlines logo]()
$340
Find flight deals from Santa Cruz de la Sierra to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $402 (CheapOair) |
One-way from | $230 (SmartFares) |
Popular in | July |
Cheapest in | September |
Average price | $610 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Cruz de la Sierra to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Santa Cruz de la SierraSantiago
VVI - SCL
VVISCL
Santa Cruz de la Sierra Viru Viru Intl
Mon 8/24
8:00 am-11:15 am
Nonstop3h 15m
Santiago Arturo Merino Benitez
Mon 8/31
12:10 pm-3:25 pm
Nonstop3h 15m
$402
Santa Cruz de la SierraSantiago
VVI - SCL
VVISCL
Santa Cruz de la Sierra Viru Viru Intl
Sat 7/11
8:00 am-11:15 am
Nonstop3h 15m
Santiago Arturo Merino Benitez
Sat 7/18
12:10 pm-3:25 pm
Nonstop3h 15m
$424
Santa Cruz de la SierraSantiago
VVI - SCL
VVISCL
Santa Cruz de la Sierra Viru Viru Intl
Mon 8/24
8:00 am-11:15 am
Nonstop3h 15m
Santiago Arturo Merino Benitez
Mon 8/31
2:35 pm-1:10 am
1 stop10h 35m
$448
Santa Cruz de la SierraSantiago
VVI - SCL
VVISCL
Santa Cruz de la Sierra Viru Viru Intl
Mon 10/26
8:00 am-11:15 am
Nonstop2h 15m
Santiago Arturo Merino Benitez
Tue 11/3
7:45 pm-4:35 am
1 stop9h 50m
$524
Santa Cruz de la SierraSantiago
VVI - SCL
VVISCL
Santa Cruz de la Sierra Viru Viru Intl
Thu 9/24
11:15 am-2:24 pm
Nonstop2h 09m
Santiago Arturo Merino Benitez
Sun 9/27
8:50 pm-1:10 am
1 stop29h 20m
$536
Cheapest one-way
Quickest one-way
Santa Cruz de la SierraSantiago
VVI - SCL
VVISCL
Santa Cruz de la Sierra Viru Viru Intl
Mon 6/22
8:00 am-11:15 am
Nonstop3h 15m
$230
Santa Cruz de la SierraSantiago
VVI - SCL
VVISCL
Santa Cruz de la Sierra Viru Viru Intl
Mon 7/20
8:00 am-11:15 am
Nonstop3h 15m
$247
Santa Cruz de la SierraSantiago
VVI - SCL
VVISCL
Santa Cruz de la Sierra Viru Viru Intl
Mon 6/8
8:00 am-11:15 am
Nonstop3h 15m
$251
Santa Cruz de la SierraSantiago
VVI - SCL
VVISCL
Santa Cruz de la Sierra Viru Viru Intl
Fri 6/12
2:20 am-5:20 pm
1 stop15h 00m
$297
Santa Cruz de la SierraSantiago
VVI - SCL
VVISCL
Santa Cruz de la Sierra Viru Viru Intl
Sun 6/7
1:10 am-11:36 pm
2 stops22h 26m
$324
Showing 1-10 of 12 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Cruz de la Sierra to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Santa Cruz de la Sierra with our price prediction graph.
VVI-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Cruz de la Sierra to Santiago
Prices
Delays
How far ahead should I book a flight from Santa Cruz de la Sierra to Santiago?
The best time to book flights from Santa Cruz de la Sierra to Santiago is 52 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santiago?
Currently, September is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santiago (average of $471). Flying from Santa Cruz de la Sierra to Santiago in July is currently the most expensive (average of $633). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from VVI to SCL?
Find hourly flight availability from Santa Cruz de la Sierra to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 11, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santa Cruz de la Sierra to Santiago as you normally would.
How often are flights from Santa Cruz de la Sierra to Santiago delayed?
About 10% of weekly flights between Santa Cruz de la Sierra and Santiago have experienced delays in the past year, with the average delay time being 96 minutes.
What is the most punctual flight time for Santa Cruz de la Sierra to Santiago flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Santa Cruz de la Sierra to Santiago flights?
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 8% of flights being delayed.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 11, 2026.
Read through reviews of airlines operating flights from Santa Cruz de la Sierra to Santiago, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.0
Boarding
7.5
Overall
7.4
Comfort
7.3
Crew
8.0
Food
6.7
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Entertainment
7.0
Boarding
7.5
Overall
7.4
Comfort
7.3
Crew
8.0
Food
6.7
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Related info for your journey
Find useful and relevant information for your journey from Santa Cruz de la Sierra to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Santa Cruz de la Sierra to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Santa Cruz de la Sierra to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Santa Cruz de la Sierra and Santiago flights
Browse other Santa Cruz de la Sierra and Santiago flight options. Last updated on May 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 11, 2026.
Top airline flying from Santa Cruz de la Sierra to Santiago
Discover the top airline that operate flights from Santa Cruz de la Sierra to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$467 | Average$584 | FlexibilityNo cancel fee | On-time81% |