$491+ Cheap flights from Santa Cruz de la Sierra (VVI) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SDQ
Jun 11 — Jun 181
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Cruz de la Sierra to Santo Domingo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santa Cruz de la Sierra to Santo DomingoExplore the most affordable flight options available from Santa Cruz de la Sierra to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
Explore the most affordable flight options available from Santa Cruz de la Sierra to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
This Avianca deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:35 am
VVI
- SDQ
1 stop8h 15m
Avianca
Thu 7/96:50 pm
SDQ
- VVI
1 stop7h 40m
Avianca
Deal found 5/11![Avianca logo]()
$886
This Copa Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:12 am
VVI
- SDQ
1 stop15h 03m
Copa Airlines
Fri 11/2012:40 pm
SDQ
- VVI
1 stop10h 10m
Copa Airlines
Deal found 5/7![Copa Airlines logo]()
$889
This Copa Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/261:12 am
VVI
- SDQ
1 stop15h 03m
Copa Airlines
Thu 7/306:07 am
SDQ
- VVI
1 stop16h 33m
Copa Airlines
Deal found 5/7![Copa Airlines logo]()
$915
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:35 am
VVI
- SDQ
2 stops12h 54m
Multiple Airlines
Mon 10/512:45 pm
SDQ
- VVI
1 stop13h 45m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$989
This Priceline deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:55 pm
VVI
- SDQ
2 stops23h 00m
Multiple Airlines
Mon 6/296:50 pm
SDQ
- VVI
1 stop7h 40m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$1,000
This FlightHub deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:55 pm
VVI
- SDQ
2 stops40h 55m
Multiple Airlines
Thu 7/96:50 pm
SDQ
- VVI
1 stop7h 40m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$1,038
This Copa Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:12 am
VVI
- SDQ
1 stop15h 03m
Copa Airlines
Fri 7/312:17 pm
SDQ
- VVI
1 stop8h 23m
Copa Airlines
Deal found 5/11![Copa Airlines logo]()
$1,047
This Copa Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:12 am
VVI
- SDQ
1 stop15h 03m
Copa Airlines
Mon 7/1312:43 pm
SDQ
- VVI
1 stop14h 52m
Copa Airlines
Deal found 5/8![Copa Airlines logo]()
$1,051
Best flights from Santa Cruz de la Sierra to Santo DomingoDiscover carefully curated flight deals from Santa Cruz de la Sierra to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
Discover carefully curated flight deals from Santa Cruz de la Sierra to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
This Avianca deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:35 am
VVI
- SDQ
1 stop8h 15m
Avianca
Mon 10/56:50 pm
SDQ
- VVI
1 stop7h 40m
Avianca
Deal found 5/8![Avianca logo]()
$886
This Copa Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:12 am
VVI
- SDQ
1 stop15h 03m
Copa Airlines
Fri 11/2012:40 pm
SDQ
- VVI
1 stop10h 10m
Copa Airlines
Deal found 5/7![Copa Airlines logo]()
$889
This Priceline deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:55 pm
VVI
- SDQ
2 stops23h 00m
Multiple Airlines
Mon 6/296:50 pm
SDQ
- VVI
1 stop7h 40m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$1,000
This Avianca deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/213:35 am
VVI
- SDQ
1 stop8h 15m
Avianca
Mon 6/2912:45 pm
SDQ
- VVI
1 stop13h 45m
Avianca
Deal found 5/7![Avianca logo]()
$886
This Copa Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/261:12 am
VVI
- SDQ
1 stop15h 03m
Copa Airlines
Thu 7/306:07 am
SDQ
- VVI
1 stop16h 33m
Copa Airlines
Deal found 5/7![Copa Airlines logo]()
$915
This Avianca deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:35 am
VVI
- SDQ
1 stop8h 15m
Avianca
Thu 7/96:50 pm
SDQ
- VVI
1 stop7h 40m
Avianca
Deal found 5/11![Avianca logo]()
$886
This FlightHub deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:55 pm
VVI
- SDQ
2 stops40h 55m
Multiple Airlines
Thu 7/912:45 pm
SDQ
- VVI
1 stop13h 45m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$1,038
This Copa Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:12 am
VVI
- SDQ
1 stop15h 03m
Copa Airlines
Fri 7/312:17 pm
SDQ
- VVI
1 stop8h 23m
Copa Airlines
Deal found 5/11![Copa Airlines logo]()
$1,047
Last-minute flights from Santa Cruz de la Sierra to Santo DomingoDiscover last-minute flight deals from Santa Cruz de la Sierra to Santo Domingo. Data last updated May 12, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Cruz de la Sierra to Santo Domingo. Data last updated May 12, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:55 pm
VVI
- SDQ
2 stops23h 00m
Multiple Airlines
Mon 6/296:50 pm
SDQ
- VVI
1 stop7h 40m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$1,000
This Avianca deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:35 am
VVI
- SDQ
1 stop8h 15m
Avianca
Thu 7/96:50 pm
SDQ
- VVI
1 stop7h 40m
Avianca
Deal found 5/11![Avianca logo]()
$886
This FlightHub deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:55 pm
VVI
- SDQ
2 stops40h 55m
Multiple Airlines
Thu 7/96:50 pm
SDQ
- VVI
1 stop7h 40m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$1,038
One-way flights from Santa Cruz de la Sierra to Santo DomingoSearch for one-way flight options from Santa Cruz de la Sierra to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
Search for one-way flight options from Santa Cruz de la Sierra to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
This Avianca deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:35 am
VVI
- SDQ
1 stop8h 15m
Avianca
Deal found 5/8![Avianca logo]()
$491
This Avianca deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:35 am
VVI
- SDQ
1 stop14h 20m
Avianca
Deal found 5/9![Avianca logo]()
$492
This deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/263:35 am
VVI
- SDQ
1 stop8h 15m
Avianca
Deal found 5/9![Avianca logo]()
$519
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:35 pm
VVI
- SDQ
3 stops58h 10m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$533
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/263:35 am
VVI
- SDQ
2 stops20h 22m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$542
This Copa Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/61:12 am
VVI
- SDQ
1 stop11h 56m
Copa Airlines
Deal found 5/10![Copa Airlines logo]()
$548
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:35 am
VVI
- SDQ
3 stops34h 02m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$596
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:50 pm
VVI
- SDQ
3 stops44h 53m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$642
Find flight deals from Santa Cruz de la Sierra to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $886 (Avianca) |
One-way from | $491 (Avianca) |
Popular in | April |
Cheapest in | September |
Average price | $708 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Cruz de la Sierra to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Santa Cruz de la SierraSanto Domingo
VVI - SDQ
VVISDQ
Santa Cruz de la Sierra Viru Viru Intl
Thu 9/24
3:35 am-11:50 am
1 stop8h 15m
Santo Domingo Las Americas
Mon 10/5
6:50 pm-2:30 am
1 stop7h 40m
$886
Santa Cruz de la SierraSanto Domingo
VVI - SDQ
VVISDQ
Santa Cruz de la Sierra Viru Viru Intl
Sun 6/21
3:35 am-11:50 am
1 stop8h 15m
Santo Domingo Las Americas
Mon 6/29
12:45 pm-2:30 am
1 stop13h 45m
$886
Santa Cruz de la SierraSanto Domingo
VVI - SDQ
VVISDQ
Santa Cruz de la Sierra Viru Viru Intl
Sat 6/27
3:35 am-11:50 am
1 stop8h 15m
Santo Domingo Las Americas
Thu 7/9
6:50 pm-2:30 am
1 stop7h 40m
$886
Santa Cruz de la SierraSanto Domingo
VVI - SDQ
VVISDQ
Santa Cruz de la Sierra Viru Viru Intl
Tue 9/15
1:12 am-4:15 pm
1 stop15h 03m
Santo Domingo Las Americas
Fri 11/20
12:40 pm-10:50 pm
1 stop10h 10m
$889
Santa Cruz de la SierraSanto Domingo
VVI - SDQ
VVISDQ
Santa Cruz de la Sierra Viru Viru Intl
Sun 7/26
1:12 am-4:15 pm
1 stop15h 03m
Santo Domingo Las Americas
Thu 7/30
6:07 am-10:40 pm
1 stop16h 33m
$915
Santa Cruz de la SierraSanto Domingo
VVI - SDQ
VVISDQ
Santa Cruz de la Sierra Viru Viru Intl
Mon 6/22
6:55 pm-5:55 pm
2 stops23h 00m
Santo Domingo Las Americas
Mon 6/29
6:50 pm-2:30 am
1 stop7h 40m
$1,000
Santa Cruz de la SierraSanto Domingo
VVI - SDQ
VVISDQ
Santa Cruz de la Sierra Viru Viru Intl
Sun 6/28
6:55 pm-11:50 am
2 stops40h 55m
Santo Domingo Las Americas
Thu 7/9
12:45 pm-2:30 am
1 stop13h 45m
$1,038
Santa Cruz de la SierraSanto Domingo
VVI - SDQ
VVISDQ
Santa Cruz de la Sierra Viru Viru Intl
Thu 7/2
1:12 am-4:15 pm
1 stop15h 03m
Santo Domingo Las Americas
Fri 7/31
2:17 pm-10:40 pm
1 stop8h 23m
$1,047
Cheapest one-way
Santa Cruz de la SierraSanto Domingo
VVI - SDQ
VVISDQ
Santa Cruz de la Sierra Viru Viru Intl
Tue 5/26
3:35 am-5:55 pm
1 stop14h 20m
$491
Quickest one-way
Santa Cruz de la SierraSanto Domingo
VVI - SDQ
VVISDQ
Santa Cruz de la Sierra Viru Viru Intl
Wed 5/20
3:35 am-11:50 am
1 stop8h 15m
$491
Showing 1-10 of 15 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Cruz de la Sierra to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Santa Cruz de la Sierra with our price prediction graph.
VVI-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Cruz de la Sierra to Santo Domingo
How far ahead should I book a flight from Santa Cruz de la Sierra to Santo Domingo?
The price you pay for your flight from Santa Cruz de la Sierra to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 6 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santo Domingo?
Currently, September is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santo Domingo (average of $704). Flying from Santa Cruz de la Sierra to Santo Domingo in April is currently the most expensive (average of $945). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Cruz de la Sierra to Santo Domingo?
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated May 12, 2026.
Read reviews from past customers who have flown Copa Airlines and Avianca from Santa Cruz de la Sierra to Santo Domingo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.5
Comfort
7.4
Food
6.8
Boarding
7.8
Crew
8.1
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Overall
7.5
Comfort
7.4
Food
6.8
Boarding
7.8
Crew
8.1
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Overall
7.5
Comfort
7.4
Food
6.8
Boarding
7.8
Crew
8.1
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Related info for your journey
Find useful and relevant information for your journey from Santa Cruz de la Sierra to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Santa Cruz de la Sierra and Santo Domingo flights
Browse other Santa Cruz de la Sierra and Santo Domingo flight options. Last updated on May 12, 2026.
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Other flights to Santo Domingo
Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 12, 2026.
Top 2 airlines flying from Santa Cruz de la Sierra to Santo Domingo
Discover the top 2 airlines that operate flights from Santa Cruz de la Sierra to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$628 | Average$786 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$688 | Average$747 | FlexibilityNo cancel fee | On-time71% |