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$574+ Cheap flights from Rome (ROM) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — SCL
Jun 13 — Jun 201
Sat 6/13
Sat 6/20
1 adult, Economy
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Cheap flight deals from Rome to Santiago

Cheapest flights from Rome to Santiago
Explore the most affordable flight options available from Rome to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 14, 2026.

This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:45 am
FCO
-
SCL
1 stop27h 30m
Delta
Sun 6/78:40 pm
SCL
-
FCO
1 stop28h 55m
Delta
Deal found 5/14$839
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:30 pm
FCO
-
SCL
1 stop22h 10m
Delta
Tue 11/1711:10 pm
SCL
-
FCO
1 stop29h 05m
Delta
Deal found 5/10$843
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:00 pm
FCO
-
SCL
2 stops46h 40m
Delta
Sun 11/1511:10 pm
SCL
-
FCO
1 stop29h 05m
Delta
Deal found 5/10$844
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/79:00 am
FCO
-
SCL
2 stops28h 15m
Delta
Mon 9/288:40 pm
SCL
-
FCO
2 stops30h 15m
Delta
Deal found 5/13$850
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/301:10 pm
FCO
-
SCL
2 stops48h 05m
Delta
Sat 6/68:40 pm
SCL
-
FCO
2 stops56h 20m
Delta
Deal found 5/11$853
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:10 am
FCO
-
SCL
2 stops51h 05m
Delta
Sun 9/208:40 pm
SCL
-
FCO
2 stops38h 55m
Delta
Deal found 5/13$860
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am
FCO
-
SCL
2 stops29h 40m
Delta
Sat 11/1411:10 pm
SCL
-
FCO
2 stops31h 50m
Delta
Deal found 5/10$866
This British Airways deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:05 pm
FCO
-
SCL
1 stop31h 35m
Iberia
Sun 6/1410:40 am
SCL
-
FCO
1 stop27h 00m
Iberia
Deal found 5/14$869
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:30 am
FCO
-
SCL
2 stops30h 45m
Delta
Tue 5/268:40 pm
SCL
-
FCO
2 stops29h 15m
Delta
Deal found 5/11$875

Find flight deals from Rome to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Rome (ROM) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$839
(Delta)

One-way from

$574
(British Airways)

Popular in

April

Cheapest in

February

Average price

$1,041
Provider with most accurate pricing for Rome (ROM)-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Rome (ROM)-Santiago Arturo Merino Benitez flights.
Search Deals
From Rome (ROM) to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Rome (ROM) to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 34% potential increase in price ($668 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 21% potential price decrease ($230 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 14, 2026.
Use the filters below to find and compare flights from Rome to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 6/1

10:10 am-7:15 am

2 stops27h 05m

Santiago Arturo Merino Benitez

Sun 6/7

8:40 pm-10:05 am

2 stops31h 25m

$841

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Tue 10/27

1:30 pm-7:40 am

1 stop22h 10m

Santiago Arturo Merino Benitez

Wed 11/18

11:10 pm-11:00 am

2 stops55h 50m

$844
Quickest round-trip

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Wed 10/28

1:30 pm-7:40 am

1 stop22h 10m

Santiago Arturo Merino Benitez

Fri 11/6

11:10 pm-8:15 am

1 stop29h 05m

$958

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Tue 6/16

10:45 am-5:03 am

3 stops48h 18m

Santiago Arturo Merino Benitez

Tue 8/11

10:15 am-2:05 pm

2 stops21h 50m

$968

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Thu 10/1

3:10 pm-5:59 am

3 stops43h 49m

Santiago Arturo Merino Benitez

Thu 10/15

11:15 am-2:05 pm

2 stops21h 50m

$968

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Tue 10/13

8:00 pm-5:59 am

3 stops38h 59m

Santiago Arturo Merino Benitez

Thu 10/29

11:40 am-9:55 pm

2 stops30h 15m

$968

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Tue 10/13

6:30 am-8:15 am

2 stops30h 45m

Santiago Arturo Merino Benitez

Fri 10/30

11:10 pm-7:45 am

2 stops28h 35m

$993
Cheapest one-way

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 8/31

3:35 pm-4:59 am

3 stops43h 24m

$624
Quickest one-way

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Wed 10/28

6:45 am-6:00 am

2 stops27h 15m

$625

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 8/31

7:05 am-7:19 pm

2 stops42h 14m

$649

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/9

Showing 1-10 of 13 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Rome-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Rome-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Rome-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Rome-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rome-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Rome to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to Santiago

How far ahead should I book a flight from Rome to Santiago?

To ensure you get the cheapest price possible for a flight from Rome to Santiago, you should look to book at least 13 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Rome to Santiago?

Currently, April is the cheapest month in which you can book a flight from Rome to Santiago (average of $474). Flying from Rome to Santiago in July is currently the most expensive (average of $911). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Rome to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 14, 2026.
Read reviews from past customers who have flown LATAM Airlines from Rome to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,925 reviews

Crew

8.0

Entertainment

7.0

Food

6.7

Boarding

7.5

Comfort

7.3

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
LATAM Airlines
7.4
Good
1,925 reviews
LATAM Airlines
7.4
Good
1,925 reviews

Crew

8.0

Entertainment

7.0

Food

6.7

Boarding

7.5

Comfort

7.3

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken

Related info for your journey

Find useful and relevant information for your journey from Rome to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Rome?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Rome. Booking flights from Rome to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Rome from 0 different airlines.

  • How long is the flight from Rome to Santiago?

    Delta can get you from Rome to Santiago in just under 22h 10m. Your travel time can differ by up to . Airlines will cover a distance of 7384 mi.

  • Can I find deals for flights from Rome to Santiago that include hotel bookings?

    Yes. In addition to deals on Rome to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to Santiago.

  • Can I find deals for business class flights from Rome to Santiago?

    Yes. Cheapflights offers flight deals from Rome to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rome to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Rome to Santiago (average of $474). Flying from Rome to Santiago in July is currently the most expensive (average of $911). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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