$638+ Cheap flights from Rome (ROM) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — SCL
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Rome to SantiagoExplore the most affordable flight options available from Rome to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from Rome to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:10 pm -
1 stop24h 05m
Fri 10/3011:10 pm -
1 stop29h 05m
Deal found 8/25![Delta logo]()
$842
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:45 am -
1 stop27h 30m
Wed 10/218:40 pm -
1 stop29h 55m
Deal found 8/21![Delta logo]()
$843
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:00 am -
2 stops28h 15m
Mon 9/288:40 pm -
2 stops30h 15m
Deal found 8/26![Delta logo]()
$851
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am -
2 stops25h 40m
Thu 11/2611:10 pm -
2 stops29h 35m
Deal found 8/24![Delta logo]()
$852
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:05 am -
2 stops31h 10m
Mon 11/211:10 pm -
2 stops28h 35m
Deal found 8/25![Delta logo]()
$864
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:30 am -
2 stops30h 45m
Fri 9/188:40 pm -
2 stops56h 25m
Deal found 8/25![Delta logo]()
$873
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:10 am -
2 stops27h 05m
Fri 9/258:40 pm -
2 stops56h 25m
Deal found 8/26![Delta logo]()
$900
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:45 am -
2 stops47h 55m
Sun 11/2911:10 pm -
1 stop29h 05m
Deal found 8/24![Delta logo]()
$901
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:00 am -
2 stops28h 15m
Sun 9/278:40 pm -
2 stops54h 15m
Deal found 8/26![Delta logo]()
$909
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am -
2 stops25h 40m
Sun 11/2911:10 pm -
1 stop32h 10m
Deal found 8/24![Delta logo]()
$910
Best flights from Rome to SantiagoDiscover carefully curated flight deals from Rome to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from Rome to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/181:30 pm -
1 stop22h 10m
Thu 2/2511:10 pm -
2 stops31h 35m
Deal found 8/26![Delta logo]()
$842
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/71:10 pm -
1 stop24h 05m
Mon 9/288:40 pm -
2 stops30h 15m
Deal found 8/26![Delta logo]()
$842
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:00 am -
2 stops27h 15m
Sat 9/198:40 pm -
1 stop29h 55m
Deal found 8/23![Delta logo]()
$935
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:25 am -
1 stop25h 15m
Mon 11/3011:10 pm -
1 stop29h 05m
Deal found 8/21![Delta logo]()
$960
Last-minute flights from Rome to SantiagoDiscover last-minute flight deals from Rome to Santiago. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from Rome to Santiago. Data last updated August 26, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:05 am -
2 stops31h 10m
Fri 9/188:40 pm -
2 stops56h 25m
Deal found 8/25![Delta logo]()
$864
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:30 am -
2 stops30h 45m
Fri 9/188:40 pm -
2 stops56h 25m
Deal found 8/25![Delta logo]()
$873
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:05 am -
2 stops31h 10m
Fri 9/258:40 pm -
2 stops53h 10m
Deal found 8/26![Delta logo]()
$922
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:45 am -
1 stop27h 30m
Mon 9/288:40 pm -
2 stops30h 15m
Deal found 8/26![Delta logo]()
$842
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:10 am -
2 stops27h 05m
Fri 9/258:40 pm -
2 stops56h 25m
Deal found 8/26![Delta logo]()
$900
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:00 am -
2 stops28h 15m
Mon 9/288:40 pm -
2 stops30h 15m
Deal found 8/26![Delta logo]()
$851
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:00 am -
2 stops28h 15m
Sun 9/278:40 pm -
2 stops54h 15m
Deal found 8/26![Delta logo]()
$909
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:10 pm -
1 stop24h 05m
Fri 9/188:40 pm -
2 stops30h 15m
Deal found 8/23![Delta logo]()
$912
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:10 pm -
1 stop24h 05m
Sun 9/208:40 pm -
2 stops39h 50m
Deal found 8/21![Delta logo]()
$921
One-way flights from Rome to SantiagoSearch for one-way flight options from Rome to Santiago. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
Search for one-way flight options from Rome to Santiago. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
This Turkish Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:05 pm -
3 stops39h 05m
Deal found 8/26![Turkish Airlines logo]()
$638
This Turkish Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:05 am -
2 stops49h 51m
Deal found 8/21![Multiple Airlines logo]()
$657
This Turkish Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:05 am -
2 stops46h 17m
Deal found 8/26![Multiple Airlines logo]()
$660
This Turkish Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:40 am -
2 stops41h 35m
Deal found 8/25![Multiple Airlines logo]()
$661
This Turkish Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:05 am -
2 stops42h 27m
Deal found 8/26![Multiple Airlines logo]()
$663
This Turkish Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:05 am -
2 stops42h 27m
Deal found 8/22![Multiple Airlines logo]()
$664
This Turkish Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/711:15 am -
3 stops46h 42m
Deal found 8/25![Turkish Airlines logo]()
$665
This Turkish Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:50 pm -
2 stops47h 10m
Deal found 8/25![Turkish Airlines logo]()
$675
This LATAM Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:05 pm -
1 stop27h 25m
Deal found 8/21![LATAM Airlines logo]()
$682
This LATAM Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:05 pm -
1 stop27h 25m
Deal found 8/25![LATAM Airlines logo]()
$685
Find flight deals from Rome to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Rome (ROM) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $842 (Delta) |
One-way from | $638 (Turkish Airlines) |
Popular in | April |
Cheapest in | January |
Average price | $1,302 |
Cheapflights Fare Finder
Customize your flight search to find flights from Rome to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from Rome to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
RomeSantiago
FCO Rome Fiumicino - SCL Santiago Arturo Merino Benitez
FCOSCL
Rome Fiumicino
Mon 1/18
1:30 pm-7:40 am
1 stop22h 10m
Santiago Arturo Merino Benitez
Thu 2/25
11:10 pm-10:45 am
2 stops31h 35m
$842
RomeSantiago
FCO Rome Fiumicino - SCL Santiago Arturo Merino Benitez
FCOSCL
Rome Fiumicino
Mon 9/7
1:10 pm-8:15 am
1 stop24h 05m
Santiago Arturo Merino Benitez
Mon 9/28
8:40 pm-7:55 am
2 stops30h 15m
$842
RomeSantiago
FCO Rome Fiumicino - SCL Santiago Arturo Merino Benitez
FCOSCL
Rome Fiumicino
Mon 9/14
10:00 am-8:15 am
2 stops27h 15m
Santiago Arturo Merino Benitez
Sat 9/19
8:40 pm-7:35 am
1 stop29h 55m
$935
RomeSantiago
FCO Rome Fiumicino - SCL Santiago Arturo Merino Benitez
FCOSCL
Rome Fiumicino
Thu 11/5
10:25 am-7:40 am
1 stop25h 15m
Santiago Arturo Merino Benitez
Mon 11/30
11:10 pm-8:15 am
1 stop29h 05m
$960
Cheapest one-way
Quickest one-way
RomeSantiago
FCO Rome Fiumicino - SCL Santiago Arturo Merino Benitez
FCOSCL
Rome Fiumicino
Sat 11/7
6:40 am-8:15 pm
2 stops41h 35m
$657
RomeSantiago
FCO Rome Fiumicino - SCL Santiago Arturo Merino Benitez
FCOSCL
Rome Fiumicino
Wed 9/23
7:05 am-12:22 am
2 stops46h 17m
$660
RomeSantiago
FCO Rome Fiumicino - SCL Santiago Arturo Merino Benitez
FCOSCL
Rome Fiumicino
Mon 9/14
7:05 am-3:56 am
2 stops49h 51m
$661
RomeSantiago
FCO Rome Fiumicino - SCL Santiago Arturo Merino Benitez
FCOSCL
Rome Fiumicino
Thu 9/24
8:05 pm-8:32 pm
2 stops53h 27m
$663
RomeSantiago
FCO Rome Fiumicino - SCL Santiago Arturo Merino Benitez
FCOSCL
Rome Fiumicino
Sat 2/6
6:40 am-11:41 pm
2 stops45h 01m
$663
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Rome-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Rome-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Rome-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Rome-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rome-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Rome to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Rome with our price prediction graph.
ROM-SCL
FCO-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Rome to Santiago
ROM-SCL
FCO-SCL
What is the cheapest month to book a flight from Rome to Santiago?
Currently, September is the cheapest month in which you can book a flight from Rome to Santiago (average of $1,003). Flying from Rome to Santiago in April is currently the most expensive (average of $1,700). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Rome to Santiago?
Airfare is below average for this route at the moment.
Rome to Santiago flights typically cost between $978 and $1,350 in October.The cheapest round-trip price found within the last 5 days was $842 on Delta (Oct 15-Nov 2).
How far ahead should I book a flight from Rome to Santiago?
To ensure you get the cheapest price possible for a flight from Rome to Santiago, you should look to book at least 73 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated August 26, 2026.
Read reviews from past customers who have flown LATAM Airlines from Rome to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Boarding
7.5
Entertainment
7.0
Crew
8.0
Food
6.7
Overall
7.4
Reviews
1 / 20
8.0
ExcellentVictoria E,Mar 2026
SCL - JFK
Comfort
7.3
Boarding
7.5
Entertainment
7.0
Crew
8.0
Food
6.7
Overall
7.4
Reviews
1 / 20
8.0
ExcellentVictoria E,Mar 2026
SCL - JFK
Related info for your journey
Find useful and relevant information for your journey from Rome to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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