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$576+ Cheap flights from Rome (ROM) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — SCL
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Find cheap flights from Rome to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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3. Compare prices and book

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Cheapflights Tip: The best prices from Rome to Santiago Arturo Merino Benitez are usually found in May or March, booked 62 days in advance, depart on a Tuesday or Monday and return on a Friday

Cheap flight deals from Rome to Santiago

Cheapest flights from Rome to Santiago
Explore the most affordable flight options available from Rome to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:05 amFCO - SCL
1 stop25h 35mDelta
Mon 12/2911:10 pmSCL - FCO
1 stop31h 20mDelta
Deal found 12/17$913
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:40 pmFCO - SCL
1 stop23h 00mDelta
Tue 12/3011:10 pmSCL - FCO
1 stop31h 20mDelta
Deal found 12/17$960
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2612:40 pmFCO - SCL
1 stop23h 00mDelta
Mon 12/2911:10 pmSCL - FCO
1 stop31h 20mDelta
Deal found 12/17$972
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:40 pmFCO - SCL
1 stop23h 00mDelta
Tue 12/3011:10 pmSCL - FCO
1 stop28h 45mDelta
Deal found 12/17$1,031
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2612:40 pmFCO - SCL
1 stop23h 00mDelta
Tue 12/309:30 pmSCL - FCO
1 stop30h 25mDelta
Deal found 12/17$1,089
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:05 amFCO - SCL
1 stop24h 05mDelta
Sat 12/279:30 pmSCL - FCO
1 stop30h 25mDelta
Deal found 12/17$1,090
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:05 amFCO - SCL
1 stop24h 05mDelta
Mon 12/2911:10 pmSCL - FCO
1 stop31h 20mDelta
Deal found 12/17$1,108
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:40 pmFCO - SCL
1 stop23h 00mDelta
Sun 12/2811:10 pmSCL - FCO
1 stop28h 45mDelta
Deal found 12/17$1,190
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:05 amFCO - SCL
1 stop25h 35mDelta
Tue 12/3011:10 pmSCL - FCO
1 stop28h 45mDelta
Deal found 12/17$1,225
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2712:40 pmFCO - SCL
1 stop23h 00mDelta
Mon 12/2911:10 pmSCL - FCO
1 stop31h 20mDelta
Deal found 12/17$1,278

Find flight deals from Rome to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Rome (ROM) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$842
(Delta)

One-way from

$576
(LEVEL)

Popular in

July

Cheapest in

May

Average price

$1,149
Provider with most accurate pricing for Rome (ROM)-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Rome (ROM)-Santiago Arturo Merino Benitez flights.
Search Deals
From Rome (ROM) to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Rome (ROM) to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($153 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Rome to Santiago that are best for you.

Fly from

Rome

Fly to

Santiago

Route

Depart

Return

Price

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Thu 1/15

12:00 pm-7:40 am

2 stops47h 40m

Santiago Arturo Merino Benitez

Thu 3/26

10:10 pm-6:05 am

2 stops27h 55m

$842

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Fri 1/16

12:40 pm-7:40 am

1 stop23h 00m

Santiago Arturo Merino Benitez

Wed 3/25

10:10 pm-8:45 am

2 stops30h 35m

$842

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Wed 1/14

6:00 am-6:10 am

2 stops28h 10m

Santiago Arturo Merino Benitez

Sun 3/22

10:10 pm-10:45 pm

2 stops44h 35m

$882

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Thu 1/15

12:40 pm-7:40 am

1 stop23h 00m

Santiago Arturo Merino Benitez

Sat 3/21

10:10 pm-9:10 am

2 stops31h 00m

$882

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Thu 1/15

12:00 pm-7:40 am

2 stops47h 40m

Santiago Arturo Merino Benitez

Tue 3/24

10:10 pm-4:25 pm

2 stops38h 15m

$882

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Thu 1/15

12:00 pm-7:40 am

2 stops47h 40m

Santiago Arturo Merino Benitez

Wed 3/25

10:10 pm-4:25 pm

2 stops38h 15m

$882

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Sun 2/1

12:40 pm-7:40 am

1 stop23h 00m

Santiago Arturo Merino Benitez

Sun 2/15

11:10 pm-10:30 am

1 stop31h 20m

$900

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Wed 1/14

6:00 am-7:40 am

2 stops29h 40m

Santiago Arturo Merino Benitez

Tue 3/24

10:10 pm-4:25 pm

2 stops38h 15m

$904

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 1/12

12:45 pm-6:10 am

2 stops45h 25m

Santiago Arturo Merino Benitez

Wed 3/25

10:10 pm-4:25 pm

2 stops38h 15m

$913

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Fri 5/29

10:30 am-8:45 am

1 stop28h 15m

$576

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 20 results
1
2

Compare providers for flights from Rome to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Rome to Santiago in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Rome-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Rome-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Rome-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Rome-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rome-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Rome to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to Santiago

How far ahead should I book a flight from Rome to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Rome to Santiago. Price data was last updated on December 12, 2025.

To ensure you get the cheapest price possible for a flight from Rome to Santiago, you should look to book at least 62 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Rome to Santiago?

Currently, May is the cheapest month in which you can book a flight from Rome to Santiago (average of $448). Flying from Rome to Santiago in August is currently the most expensive (average of $1,090). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Rome to Santiago?

Related info for your journey

Find useful and relevant information for your journey from Rome to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Rome?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Rome. Booking flights from Rome to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Rome from 0 different airlines.

  • How long is the flight from Rome to Santiago?

    Delta can get you from Rome to Santiago in just under 47h 40m. Your travel time can differ by up to . Airlines will cover a distance of 7384 mi.

  • Can I find deals for flights from Rome to Santiago that include hotel bookings?

    Yes. In addition to deals on Rome to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to Santiago.

  • Can I find deals for business class flights from Rome to Santiago?

    Yes. Cheapflights offers flight deals from Rome to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rome to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Rome to Santiago (average of $448). Flying from Rome to Santiago in August is currently the most expensive (average of $1,090). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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