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$476+ Cheap flights from Rome (ROM) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — SCL
Mar 9 — Mar 161
Mon 3/9
Mon 3/16
1 adult, Economy
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Cheap flight deals from Rome to Santiago

Cheapest flights from Rome to Santiago
Explore the most affordable flight options available from Rome to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.

This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:00 am
FCO
-
SCL
2 stops48h 40m
Delta
Wed 3/1810:25 pm
SCL
-
FCO
2 stops29h 15m
Delta
Deal found 2/6$844
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/812:00 pm
FCO
-
SCL
2 stops47h 40m
Delta
Mon 2/2311:10 pm
SCL
-
FCO
2 stops30h 35m
Delta
Deal found 2/5$846
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:40 am
FCO
-
SCL
1 stop24h 00m
Delta
Wed 4/88:40 pm
SCL
-
FCO
2 stops32h 20m
Delta
Deal found 2/6$853
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:10 am
FCO
-
SCL
2 stops29h 30m
Delta
Wed 3/1810:25 pm
SCL
-
FCO
2 stops29h 15m
Delta
Deal found 2/6$877
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:40 am
FCO
-
SCL
1 stop24h 00m
Delta
Tue 3/1710:25 pm
SCL
-
FCO
2 stops30h 45m
Delta
Deal found 2/6$885
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:00 am
FCO
-
SCL
2 stops48h 40m
Delta
Thu 3/1910:25 pm
SCL
-
FCO
2 stops53h 15m
Delta
Deal found 2/6$903
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:10 am
FCO
-
SCL
2 stops29h 30m
Delta
Tue 3/1710:25 pm
SCL
-
FCO
2 stops30h 45m
Delta
Deal found 2/6$917

Find flight deals from Rome to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Rome (ROM) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$844
(Delta)

One-way from

$476
(Kiwi.com)

Popular in

July

Cheapest in

May

Average price

$973
Provider with most accurate pricing for Rome (ROM)-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Rome (ROM)-Santiago Arturo Merino Benitez flights.
Search Deals
From Rome (ROM) to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Rome (ROM) to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($150 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Rome to Santiago that are best for you.

Fly from

Rome

Fly to

Santiago

Route

Depart

Return

Price

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Fri 3/6

12:00 pm-7:40 am

2 stops47h 40m

Santiago Arturo Merino Benitez

Wed 3/18

10:25 pm-6:05 am

2 stops27h 40m

$844

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 3/9

9:05 am-7:40 am

1 stop26h 35m

Santiago Arturo Merino Benitez

Wed 4/8

8:40 pm-7:35 am

1 stop28h 55m

$844

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Sat 3/7

6:10 am-7:40 am

2 stops29h 30m

Santiago Arturo Merino Benitez

Wed 3/18

10:25 pm-7:40 am

2 stops29h 15m

$877

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Fri 3/6

12:00 pm-7:40 am

2 stops47h 40m

Santiago Arturo Merino Benitez

Tue 3/17

10:25 pm-9:10 am

2 stops30h 45m

$885

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 3/9

11:40 am-7:40 am

1 stop24h 00m

Santiago Arturo Merino Benitez

Tue 3/17

10:25 pm-9:10 am

2 stops30h 45m

$885

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 3/9

9:05 am-7:40 am

1 stop26h 35m

Santiago Arturo Merino Benitez

Thu 3/19

10:25 pm-7:40 am

2 stops53h 15m

$903

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Thu 3/5

6:10 am-7:40 am

2 stops29h 30m

Santiago Arturo Merino Benitez

Wed 3/18

10:25 pm-6:05 am

2 stops27h 40m

$938

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Tue 3/3

6:10 am-7:40 am

2 stops29h 30m

Santiago Arturo Merino Benitez

Wed 3/18

10:25 pm-7:40 am

2 stops29h 15m

$938

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Wed 5/13

2:45 pm-7:25 am

1 stop22h 40m

$534

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 5/18

10:35 pm-11:20 pm

2 stops30h 45m

$539

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/5

Showing 1-10 of 19 results
1
2
  • Most accurate provider: When it comes to deals on Rome-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Rome-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Rome-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Rome-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rome-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Rome to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to Santiago

How far ahead should I book a flight from Rome to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Rome to Santiago. Price data was last updated on February 6, 2026.

To ensure you get the cheapest price possible for a flight from Rome to Santiago, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Rome to Santiago?

Currently, May is the cheapest month in which you can book a flight from Rome to Santiago (average of $500). Flying from Rome to Santiago in August is currently the most expensive (average of $1,090). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Rome to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Rome?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Rome. Booking flights from Rome to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Rome from 0 different airlines.

  • How long is the flight from Rome to Santiago?

    Delta can get you from Rome to Santiago in just under 47h 40m. Your travel time can differ by up to . Airlines will cover a distance of 7384 mi.

  • Can I find deals for flights from Rome to Santiago that include hotel bookings?

    Yes. In addition to deals on Rome to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to Santiago.

  • Can I find deals for business class flights from Rome to Santiago?

    Yes. Cheapflights offers flight deals from Rome to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rome to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Rome to Santiago (average of $500). Flying from Rome to Santiago in August is currently the most expensive (average of $1,090). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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