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$429+ Cheap flights from Rome (ROM) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — SCL
Apr 26 — May 31
Sun 4/26
Sun 5/3
1 adult, Economy
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Cheap flight deals from Rome to Santiago

Cheapest flights from Rome to Santiago
Explore the most affordable flight options available from Rome to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.

This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:45 am
FCO
-
SCL
1 stop27h 30m
Delta
Thu 10/18:40 pm
SCL
-
FCO
2 stops53h 10m
Delta
Deal found 3/27$828
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:10 am
FCO
-
SCL
2 stops27h 05m
Delta
Mon 4/278:40 pm
SCL
-
FCO
2 stops29h 15m
Delta
Deal found 3/24$830
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:05 am
FCO
-
SCL
1 stop25h 35m
Delta
Fri 11/2011:10 pm
SCL
-
FCO
1 stop28h 45m
Delta
Deal found 3/26$831
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:05 am
FCO
-
SCL
2 stops25h 35m
Delta
Mon 11/2311:10 pm
SCL
-
FCO
1 stop28h 45m
Delta
Deal found 3/26$840
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
FCO
-
SCL
2 stops29h 40m
Delta
Thu 11/1911:10 pm
SCL
-
FCO
2 stops30h 35m
Delta
Deal found 3/26$853
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/812:45 pm
FCO
-
SCL
2 stops46h 55m
Delta
Sat 11/2111:10 pm
SCL
-
FCO
1 stop28h 45m
Delta
Deal found 3/26$862
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:10 pm
FCO
-
SCL
1 stop24h 05m
Delta
Thu 4/238:40 pm
SCL
-
FCO
1 stop32h 10m
Delta
Deal found 3/27$875
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:10 am
FCO
-
SCL
2 stops27h 05m
Delta
Sat 4/258:40 pm
SCL
-
FCO
1 stop28h 55m
Delta
Deal found 3/26$889

Find flight deals from Rome to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Rome (ROM) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$830
(Delta)

One-way from

$429
(LEVEL)

Popular in

August

Cheapest in

May

Average price

$1,023
Provider with most accurate pricing for Rome (ROM)-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Rome (ROM)-Santiago Arturo Merino Benitez flights.
Search Deals
From Rome (ROM) to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Rome (ROM) to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($128 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Rome to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 4/13

9:45 am-7:15 am

1 stop27h 30m

Santiago Arturo Merino Benitez

Mon 4/27

8:40 pm-10:05 am

2 stops31h 25m

$831

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Tue 6/16

10:45 am-8:30 am

2 stops27h 45m

Santiago Arturo Merino Benitez

Tue 8/11

10:15 am-2:05 pm

2 stops21h 50m

$966
Quickest round-trip

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 6/15

3:35 pm-8:30 am

2 stops22h 55m

Santiago Arturo Merino Benitez

Tue 6/30

10:15 am-6:25 pm

2 stops26h 10m

$1,069

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Sun 8/16

6:30 am-7:15 am

2 stops30h 45m

Santiago Arturo Merino Benitez

Wed 8/26

8:40 pm-9:35 am

2 stops30h 55m

$1,083

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Wed 6/10

8:00 pm-8:30 am

2 stops42h 30m

Santiago Arturo Merino Benitez

Wed 7/15

10:15 am-6:25 pm

2 stops26h 10m

$1,088

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Thu 9/17

9:45 am-8:15 am

1 stop27h 30m

Santiago Arturo Merino Benitez

Fri 10/2

8:40 pm-7:35 am

1 stop29h 55m

$1,145

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Sun 8/16

9:00 pm-7:30 am

1 stop40h 30m

Santiago Arturo Merino Benitez

Sun 9/6

11:00 pm-11:45 pm

2 stops19h 45m

$1,190

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Tue 8/18

9:45 am-7:15 am

1 stop27h 30m

Santiago Arturo Merino Benitez

Sat 9/5

8:40 pm-5:30 pm

2 stops38h 50m

$1,193

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Wed 4/22

9:45 am-7:15 am

1 stop27h 30m

Santiago Arturo Merino Benitez

Wed 4/29

8:40 pm-7:35 am

1 stop28h 55m

$1,264

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Wed 8/12

1:10 pm-7:15 am

1 stop24h 05m

Santiago Arturo Merino Benitez

Fri 8/28

8:40 pm-9:35 am

2 stops54h 55m

$1,338

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 18 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Rome-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Rome-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Rome-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Rome-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rome-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Rome to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to Santiago

How far ahead should I book a flight from Rome to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Rome to Santiago. Price data was last updated on March 13, 2026.

To ensure you get the cheapest price possible for a flight from Rome to Santiago, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Rome to Santiago?

Currently, April is the cheapest month in which you can book a flight from Rome to Santiago (average of $498). Flying from Rome to Santiago in August is currently the most expensive (average of $1,115). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Rome to Santiago?

Related info for your journey

Find useful and relevant information for your journey from Rome to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Rome?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Rome. Booking flights from Rome to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Rome from 0 different airlines.

  • How long is the flight from Rome to Santiago?

    Delta and Turkish Airlines can get you from Rome to Santiago in just under 27h 05m. Your travel time can differ by up to 15h 25m. Airlines will cover a distance of 7384 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Rome to Santiago that include hotel bookings?

    Yes. In addition to deals on Rome to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to Santiago.

  • Can I find deals for business class flights from Rome to Santiago?

    Yes. Cheapflights offers flight deals from Rome to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rome to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Rome to Santiago (average of $498). Flying from Rome to Santiago in August is currently the most expensive (average of $1,115). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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