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$346+ Cheap flights from Jacksonville (JAX) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — SCL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Jacksonville to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$684
(LATAM Airlines)

One-way from

$346
(Kiwi.com)

Popular in

March

Cheapest in

October

Average price

$853
From Jacksonville to Santiago Arturo Merino Benitez
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One-way flight from Jacksonville to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 5% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Jacksonville to Santiago

Cheapest flights from Jacksonville to Santiago
Explore the most affordable flight options available from Jacksonville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:17 amJAX - SCL
2 stops17h 28mDelta
Mon 10/68:15 amSCL - JAX
2 stops15h 41mDelta
Deal found 9/10$684
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/212:45 pmJAX - SCL
2 stops16h 55mLATAM Airlines
Mon 10/68:15 amSCL - JAX
2 stops16h 44mLATAM Airlines
Deal found 9/9$688
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:32 pmJAX - SCL
1 stop13h 08mDelta
Sat 11/156:30 pmSCL - JAX
2 stops19h 32mDelta
Deal found 9/11$724
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3012:54 pmJAX - SCL
2 stops19h 01mAmerican Airlines
Sat 11/1511:15 pmSCL - JAX
1 stop14h 12mAmerican Airlines
Deal found 9/9$728
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:05 pmJAX - SCL
1 stop13h 45mUnited Airlines
Sat 11/110:45 pmSCL - JAX
1 stop13h 52mUnited Airlines
Deal found 9/10$764
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:22 pmJAX - SCL
1 stop11h 33mAmerican Airlines
Mon 10/69:55 pmSCL - JAX
1 stop12h 40mAmerican Airlines
Deal found 9/8$844
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:10 pmJAX - SCL
1 stop11h 30mLATAM Airlines
Fri 11/144:35 amSCL - JAX
2 stops21h 31mLATAM Airlines
Deal found 9/9$864
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:28 pmJAX - SCL
2 stops18h 37mLATAM Airlines
Fri 1/912:25 amSCL - JAX
2 stops25h 36mLATAM Airlines
Deal found 9/9$994

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Jacksonville to Santiago that are best for you.

Fly from

Jacksonville

Fly to

Santiago

Route

Depart

Return

Price

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Thu 10/2

5:01 pm-2:25 pm

2 stops20h 24m

Santiago Arturo Merino Benitez

Mon 10/6

9:40 pm-8:59 am

1 stop12h 19m

$684

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Thu 10/2

11:17 am-5:45 am

2 stops17h 28m

Santiago Arturo Merino Benitez

Mon 10/6

8:15 am-10:56 pm

2 stops15h 41m

$684

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Thu 10/30

11:27 am-6:35 am

2 stops18h 08m

Santiago Arturo Merino Benitez

Fri 11/14

12:55 am-7:03 pm

2 stops20h 08m

$724

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Mon 10/6

4:16 pm-3:35 am

3 stops34h 19m

$346

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Wed 10/15

1:26 pm-6:00 am

2 stops15h 34m

$493

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Mon 10/6

7:35 am-4:30 am

2 stops19h 55m

$543

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Jacksonville to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Santiago

What is the cheapest time of day to fly from JAX to SCL?

Find hourly flight availability from Jacksonville to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 25% on flights from Jacksonville to Santiago by exploring options for tickets at noon.

How much does it cost to fly round-trip from Jacksonville to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Jacksonville to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Jacksonville to Santiago?

    There are many flights that can get you from Jacksonville to Santiago in 17h 28m. Fly via LATAM Airlines or Delta to get the fastest option. Jacksonville and Santiago are separated by a distance of 4468 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Jacksonville to Santiago round-trip?

    Our cheapest airline available from Jacksonville to Santiago is Delta. Our recent data shows that you can find tickets from as low as $657 on this airline. An additional option worth looking into is American Airlines, starting at $703. Delta is priced at 28% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Jacksonville to Santiago that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Santiago.

  • Can I find deals for business class flights from Jacksonville to Santiago?

    Yes. Cheapflights offers flight deals from Jacksonville to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Jacksonville to Santiago (average of $752). Flying from Jacksonville to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Jacksonville to Santiago

Discover the top 2 airlines that operate flights from Jacksonville to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$657Average$942FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$703Average$863FlexibilityNo cancel feeOn-time71%

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