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$280+ Cheap flights from Detroit (DTT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — SCL
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Detroit to Santiago

Cheapest flights from Detroit to Santiago
Explore the most affordable flight options available from Detroit to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:30 pmDTW - SCL
1 stop14h 20mUnited Airlines
Mon 12/2910:45 pmSCL - DTW
1 stop19h 04mUnited Airlines
Deal found 12/22$1,134
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:30 pmDTW - SCL
1 stop14h 20mUnited Airlines
Mon 12/2910:45 pmSCL - DTW
2 stops25h 45mUnited Airlines
Deal found 12/21$1,139
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:12 amDTW - SCL
2 stops21h 38mUnited Airlines
Tue 12/3010:45 pmSCL - DTW
1 stop26h 58mUnited Airlines
Deal found 12/22$1,149
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:00 amDTW - SCL
1 stop24h 50mUnited Airlines
Mon 12/2910:45 pmSCL - DTW
2 stops26h 53mUnited Airlines
Deal found 12/21$1,153
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:30 pmDTW - SCL
1 stop14h 20mUnited Airlines
Tue 12/3010:45 pmSCL - DTW
2 stops37h 48mUnited Airlines
Deal found 12/21$1,155
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:30 pmDTW - SCL
1 stop14h 20mUnited Airlines
Sun 12/2810:45 pmSCL - DTW
1 stop19h 04mUnited Airlines
Deal found 12/21$1,174
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:12 amDTW - SCL
2 stops21h 38mUnited Airlines
Sun 12/2810:45 pmSCL - DTW
2 stops25h 45mUnited Airlines
Deal found 12/21$1,179
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:12 amDTW - SCL
2 stops21h 38mUnited Airlines
Tue 12/3010:45 pmSCL - DTW
1 stop26h 58mUnited Airlines
Deal found 12/21$1,189

Find flight deals from Detroit to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$631
(Mytrip)

One-way from

$280
(Avianca Connect)

Popular in

February

Cheapest in

October

Average price

$1,166
Provider with most accurate pricing for Detroit (DTT)-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Santiago Arturo Merino Benitez flights.
Search Deals
From Detroit (DTT) to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Detroit (DTT) to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Detroit to Santiago that are best for you.

Fly from

Detroit

Fly to

Santiago

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 2/24

6:00 am-10:34 am

3 stops26h 34m

Santiago Arturo Merino Benitez

Tue 3/3

12:35 pm-9:39 pm

2 stops35h 04m

$631

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 2/23

6:36 pm-5:14 am

2 stops32h 38m

Santiago Arturo Merino Benitez

Mon 3/9

11:25 pm-9:39 pm

1 stop23h 14m

$676

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 4/4

9:41 am-5:15 am

2 stops18h 34m

Santiago Arturo Merino Benitez

Wed 4/15

11:55 pm-9:34 pm

2 stops21h 39m

$689

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 2/11

6:35 am-5:30 am

2 stops20h 55m

Santiago Arturo Merino Benitez

Mon 2/16

4:25 pm-9:11 am

2 stops18h 46m

$716

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 2/5

5:30 am-5:30 am

2 stops22h 00m

Santiago Arturo Merino Benitez

Thu 2/12

4:25 pm-9:11 am

2 stops18h 46m

$728

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 2/4

6:35 am-5:30 am

2 stops20h 55m

Santiago Arturo Merino Benitez

Thu 2/12

1:35 am-9:00 pm

2 stops21h 25m

$776

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 2/12

3:09 pm-2:30 pm

2 stops21h 21m

Santiago Arturo Merino Benitez

Wed 2/18

9:05 pm-10:43 pm

2 stops27h 38m

$819

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 1/29

11:20 am-8:15 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Tue 2/10

10:35 pm-11:30 am

1 stop14h 55m

$864

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 2/16

6:10 pm-8:50 am

2 stops36h 40m

Santiago Arturo Merino Benitez

Mon 2/23

10:45 pm-10:09 pm

2 stops25h 24m

$869

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 2/23

1:08 pm-9:25 am

2 stops18h 17m

Santiago Arturo Merino Benitez

Mon 3/9

9:15 pm-1:41 pm

2 stops17h 26m

$869

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 16 results
1
2

Compare providers for flights from Detroit to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Santiago in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Detroit-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Detroit-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Santiago

What is the cheapest time of day to fly from DTT to SCL?

Find hourly flight availability from Detroit to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

A simple way to save on the total cost of your ticket is to fly from Detroit to Santiago in the evening. If you’re flexible enough to do this you can expect to save up to 18% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 23, 2025.
Read through reviews of airlines operating flights from Detroit to Santiago, such as Delta and LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,015 reviews

Food

7.3

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,015 reviews
Delta
7.9
Good
8,015 reviews

Food

7.3

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,894 reviews
Delta
7.9
Good
8,015 reviews

Food

7.3

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit to Santiago round-trip?

    According to our current data, LATAM Airlines ($733), American Airlines ($808), and Delta ($873) offers the cheapest pricing from Detroit to Santiago. You may be able to fly from Detroit to Santiago for 30% less than the average price by searching for these airlines.

  • Can I find deals for flights from Detroit to Santiago that include hotel bookings?

    Yes. In addition to deals on Detroit to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santiago.

  • Can I find deals for business class flights from Detroit to Santiago?

    Yes. Cheapflights offers flight deals from Detroit to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Detroit to Santiago

Discover the top 3 airlines that operate flights from Detroit to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$733Average$1,418FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$808Average$1,108FlexibilityNo cancel feeOn-time71%
DeltaCheapest$873Average$1,353FlexibilityNo cancel feeOn-timeN/A

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