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$557+ Cheap flights from Detroit (DTT) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — SCL
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Detroit to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$557
(Avianca Connect)

Popular in

December

Cheapest in

October

Average price

$932
From Detroit (DTT) to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 14% potential increase in price ($186 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($66 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Detroit to Santiago

Cheapest flights from Detroit to Santiago
Explore the most affordable flight options available from Detroit to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Avianca Connect deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:52 amDTW - SCL
2 stops21h 38mMultiple Airlines
Wed 11/51:35 amSCL - DTW
2 stops19h 19mMultiple Airlines
Deal found 9/15$557
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/189:05 pmDTW - SCL
3 stops40h 40mMultiple Airlines
Sun 10/267:25 amSCL - DTW
3 stops32h 55mMultiple Airlines
Deal found 9/15$616
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:17 amDTW - SCL
3 stops29h 03mMultiple Airlines
Mon 11/1010:50 amSCL - DTW
1 stop29h 19mMultiple Airlines
Deal found 9/16$622
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:17 amDTW - SCL
3 stops29h 03mMultiple Airlines
Fri 11/1410:50 amSCL - DTW
1 stop29h 19mMultiple Airlines
Deal found 9/16$630
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:17 amDTW - SCL
2 stops31h 28mMultiple Airlines
Wed 11/1211:25 pmSCL - DTW
1 stop16h 44mMultiple Airlines
Deal found 9/14$640
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:17 amDTW - SCL
2 stops38h 58mMultiple Airlines
Mon 11/1010:50 amSCL - DTW
1 stop29h 19mMultiple Airlines
Deal found 9/16$644
This Avianca Connect deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:52 amDTW - SCL
2 stops21h 23mMultiple Airlines
Tue 11/111:35 amSCL - DTW
2 stops22h 01mMultiple Airlines
Deal found 9/14$649
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:17 amDTW - SCL
2 stops38h 58mMultiple Airlines
Fri 11/1410:50 amSCL - DTW
1 stop29h 19mMultiple Airlines
Deal found 9/16$652

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Detroit to Santiago that are best for you.

Fly from

Detroit

Fly to

Santiago

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 10/30

6:52 am-5:30 am

2 stops21h 38m

Santiago Arturo Merino Benitez

Wed 11/5

1:35 am-6:54 pm

2 stops19h 19m

$557

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 10/24

6:17 am-12:20 pm

3 stops29h 03m

Santiago Arturo Merino Benitez

Fri 11/14

10:50 am-2:09 pm

1 stop29h 19m

$631

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 10/20

6:17 am-12:20 pm

3 stops29h 03m

Santiago Arturo Merino Benitez

Wed 11/12

11:25 pm-2:09 pm

1 stop16h 44m

$642

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 10/22

6:52 am-5:15 am

2 stops21h 23m

Santiago Arturo Merino Benitez

Tue 11/11

1:35 am-9:36 pm

2 stops22h 01m

$649

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 10/24

11:04 am-5:15 am

2 stops17h 11m

Santiago Arturo Merino Benitez

Thu 11/13

11:25 pm-2:09 pm

1 stop16h 44m

$679

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 10/22

9:30 am-5:15 am

2 stops18h 45m

Santiago Arturo Merino Benitez

Thu 11/13

11:25 pm-2:09 pm

1 stop16h 44m

$679

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 10/23

9:30 am-5:15 am

2 stops18h 45m

Santiago Arturo Merino Benitez

Mon 11/10

10:50 am-2:09 pm

1 stop29h 19m

$713

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 10/18

9:05 pm-2:45 pm

3 stops40h 40m

Santiago Arturo Merino Benitez

Sat 10/25

1:35 am-11:58 am

3 stops35h 23m

$718

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 10/24

9:16 am-6:00 am

1 stop19h 44m

Santiago Arturo Merino Benitez

Sun 11/9

1:35 am-6:54 pm

2 stops19h 19m

$811

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Detroit to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Santiago

What is the cheapest time of day to fly from DTT to SCL?

Find hourly flight availability from Detroit to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

A simple way to save on the total cost of your ticket is to fly from Detroit to Santiago in the evening. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Detroit to Santiago, such as Delta and LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit to Santiago round-trip?

    According to our current data, Air Canada ($684), LATAM Airlines ($733), and Delta ($768) offers the cheapest pricing from Detroit to Santiago. You may be able to fly from Detroit to Santiago for 36% less than the average price by searching for these airlines.

  • Can I find deals for flights from Detroit to Santiago that include hotel bookings?

    Yes. In addition to deals on Detroit to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santiago.

  • Can I find deals for business class flights from Detroit to Santiago?

    Yes. Cheapflights offers flight deals from Detroit to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Detroit to Santiago (average of $752). Flying from Detroit to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Detroit to Santiago

Discover the top 4 airlines that operate flights from Detroit to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air CanadaCheapest$684Average$811FlexibilityNo cancel feeOn-time67%
LATAM AirlinesCheapest$733Average$1,272FlexibilityNo cancel feeOn-time81%
DeltaCheapest$768Average$1,262FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$822Average$1,047FlexibilityNo cancel feeOn-time71%

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