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$243+ Cheap flights from Charlotte (CLT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — SCL
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheapflights Tip: The best prices from Charlotte Douglas to Santiago Arturo Merino Benitez are usually found in September or February, booked 36 days in advance, depart on a Wednesday or Tuesday and return on a Thursday

Cheap flight deals from Charlotte to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$508
(Mytrip)

One-way from

$243
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$858
From Charlotte Douglas to Santiago Arturo Merino Benitez
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One-way flight from Charlotte Douglas to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 6% potential increase in price ($62 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Charlotte to Santiago

Cheapest flights from Charlotte to Santiago
Explore the most affordable flight options available from Charlotte to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/111:28 pmCLT - SCL
2 stops23h 57mMultiple Airlines
Thu 9/183:30 pmSCL - CLT
2 stops21h 53mMultiple Airlines
Deal found 7/28$508
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/151:11 pmCLT - SCL
1 stop17h 39mLATAM Airlines
Mon 9/2911:55 pmSCL - CLT
1 stop14h 26mLATAM Airlines
Deal found 7/28$715
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/102:30 pmCLT - SCL
1 stop16h 25mAmerican Airlines
Wed 9/179:55 pmSCL - CLT
1 stop15h 14mAmerican Airlines
Deal found 7/27$745

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Charlotte to Santiago that are best for you.

Fly from

Charlotte

Fly to

Santiago

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 9/11

1:28 pm-2:25 pm

2 stops23h 57m

Santiago Arturo Merino Benitez

Thu 9/18

3:30 pm-12:23 pm

2 stops21h 53m

$508

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 9/15

1:11 pm-7:50 am

1 stop17h 39m

Santiago Arturo Merino Benitez

Mon 9/29

11:55 pm-1:21 pm

1 stop14h 26m

$715

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 9/10

2:30 pm-7:55 am

1 stop16h 25m

Santiago Arturo Merino Benitez

Wed 9/17

9:55 pm-12:09 pm

1 stop15h 14m

$745

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 12/10

10:32 am-5:10 am

2 stops16h 38m

$243

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sun 12/7

9:30 am-12:15 pm

1 stop24h 45m

$470

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 12/9

1:15 pm-6:55 am

1 stop15h 40m

$494

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 12/11

5:30 am-6:10 am

1 stop22h 40m

$518

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sun 10/26

11:34 am-7:50 am

1 stop19h 16m

$2,118

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Charlotte to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Santiago

How far ahead should I book a flight from Charlotte to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Charlotte to Santiago. Price data was last updated on July 25, 2025.

The price you pay for your flight from Charlotte to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Charlotte to Santiago?

Currently, April is the cheapest month in which you can book a flight from Charlotte to Santiago (average of $752). Flying from Charlotte to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to SCL?

Find hourly flight availability from Charlotte to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Charlotte to Santiago in the evening. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 29, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines, and United Airlines from Charlotte to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,822 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air Canada
7.1
Good
9,826 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Charlotte to Santiago round-trip?

    Cheapflights users have booked flights from Charlotte to Santiago round-trip from $715. Another airline that can offer you cheap pricing is American Airlines. LATAM Airlines is currently priced 24% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Charlotte to Santiago one-way?

    One-way options have recently been found by users for as low as $470 on Air Canada. Other airlines that offer cheap prices include LATAM Airlines from $494 and Delta from $518 one-way.

  • Can I find deals for flights from Charlotte to Santiago that include hotel bookings?

    Yes. In addition to deals on Charlotte to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Santiago.

  • Can I find deals for business class flights from Charlotte to Santiago?

    Yes. Cheapflights offers flight deals from Charlotte to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Charlotte to Santiago (average of $752). Flying from Charlotte to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Charlotte to Santiago

Discover the top 3 airlines that operate flights from Charlotte to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$748Average$967FlexibilityNo cancel feeOn-time71%
DeltaCheapest$752Average$1,058FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$788Average$997FlexibilityNo cancel feeOn-time81%

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