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$279+ Cheap flights from Charlotte (CLT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — SCL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Charlotte to Santiago

Cheapest flights from Charlotte to Santiago
Explore the most affordable flight options available from Charlotte to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:57 pmCLT - SCL
1 stop12h 38mMultiple Airlines
Wed 12/316:00 amSCL - CLT
2 stops28h 32mMultiple Airlines
Deal found 12/11$945
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:11 amCLT - SCL
1 stop24h 14mAmerican Airlines
Wed 12/3111:15 pmSCL - CLT
1 stop15h 02mAmerican Airlines
Deal found 12/11$952
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:00 amCLT - SCL
1 stop19h 55mAmerican Airlines
Thu 12/1811:55 pmSCL - CLT
1 stop19h 44mAmerican Airlines
Deal found 12/10$1,034
This Avianca Connect deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:00 amCLT - SCL
2 stops20h 30mMultiple Airlines
Wed 12/171:35 amSCL - CLT
2 stops21h 04mMultiple Airlines
Deal found 12/10$1,054
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:09 pmCLT - SCL
2 stops61h 41mUnited Airlines
Wed 12/3110:45 pmSCL - CLT
2 stops20h 53mUnited Airlines
Deal found 12/11$1,095
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:19 amCLT - SCL
1 stop19h 51mDelta
Fri 12/2611:10 pmSCL - CLT
1 stop22h 00mDelta
Deal found 12/10$1,114
This Mytrip deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:55 pmCLT - SCL
2 stops26h 14mMultiple Airlines
Wed 12/316:00 amSCL - CLT
2 stops29h 39mMultiple Airlines
Deal found 12/11$1,136

Find flight deals from Charlotte to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$654
(FlightHub)

One-way from

$279
(eDestinos)

Popular in

April

Cheapest in

November

Average price

$958
Provider with most accurate pricing for Charlotte Douglas-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Santiago Arturo Merino Benitez flights.
Search Deals
From Charlotte Douglas to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Charlotte Douglas to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($93 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Charlotte to Santiago that are best for you.

Fly from

Charlotte

Fly to

Santiago

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 3/2

2:10 pm-6:55 am

1 stop14h 45m

Santiago Arturo Merino Benitez

Mon 3/16

10:30 pm-2:45 pm

1 stop17h 15m

$654

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 2/16

4:57 pm-7:40 am

1 stop12h 43m

Santiago Arturo Merino Benitez

Thu 2/26

11:30 pm-1:30 pm

1 stop16h 00m

$684

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 1/19

1:24 pm-10:39 am

2 stops19h 15m

Santiago Arturo Merino Benitez

Mon 2/9

11:24 am-10:55 am

2 stops25h 31m

$687

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 2/16

6:01 pm-4:00 am

2 stops31h 59m

Santiago Arturo Merino Benitez

Thu 2/26

10:35 am-3:30 pm

1 stop30h 55m

$689

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 3/5

7:00 am-3:35 am

2 stops18h 35m

Santiago Arturo Merino Benitez

Sun 3/22

5:50 am-12:19 pm

2 stops31h 29m

$753

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sat 3/7

5:28 pm-7:50 am

2 stops60h 22m

Santiago Arturo Merino Benitez

Sun 3/22

9:45 pm-10:26 am

2 stops61h 41m

$791

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 4/6

3:25 pm-6:00 am

1 stop14h 35m

Santiago Arturo Merino Benitez

Thu 4/23

10:55 pm-1:52 pm

1 stop14h 57m

$799

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sun 1/4

11:35 am-7:45 am

1 stop18h 10m

Santiago Arturo Merino Benitez

Sun 5/10

8:50 pm-5:43 pm

1 stop20h 53m

$814

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 3/5

6:59 pm-2:05 pm

2 stops17h 06m

Santiago Arturo Merino Benitez

Tue 3/24

6:40 am-11:50 pm

2 stops18h 10m

$834

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 1/19

9:13 am-2:40 pm

2 stops27h 27m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 17 results
1
2

Compare providers for flights from Charlotte to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charlotte to Santiago in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
Justfly.comPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charlotte-Santiago flights, users find the pricing of Justfly.com to be most consistent on Cheapflights vs. Justfly.com Users can find the same prices on Charlotte-Santiago flight deals on Cheapflights vs. Justfly.com >95% of the time. Price accuracy is based on data collected from Charlotte-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charlotte-Santiago flights, Cheapflights users trust Justfly.com the most. Justfly.com has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charlotte-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charlotte to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Santiago

What is the cheapest month to book a flight from Charlotte to Santiago?

Currently, December is the cheapest month in which you can book a flight from Charlotte to Santiago (average of $696). Flying from Charlotte to Santiago in May is currently the most expensive (average of $1,025). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to SCL?

Find hourly flight availability from Charlotte to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Charlotte to Santiago in the evening. If you’re flexible enough to do this you can expect to save up to 21% on your trip compared to booking a flight in the morning.

How much does it cost to fly round-trip from Charlotte to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines, and American Airlines from Charlotte to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,887 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charlotte to Santiago?

    Airlines like LATAM Airlines fly from Charlotte to Santiago in about 14h 45m. The time it takes to get you to your destination can typically vary by up to . The distance from Charlotte to Santiago is about 4783 mi.

  • What are the cheapest airlines flying from Charlotte to Santiago round-trip?

    Cheapflights users have booked flights from Charlotte to Santiago round-trip from $714. Other airlines that can offer you cheap pricing are Delta, from $752, and LATAM Airlines, from $754. American Airlines is currently priced 23% below the average price you’ll pay for this route.

  • Can I find deals for flights from Charlotte to Santiago that include hotel bookings?

    Yes. In addition to deals on Charlotte to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Santiago.

  • Can I find deals for business class flights from Charlotte to Santiago?

    Yes. Cheapflights offers flight deals from Charlotte to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Santiago?

    Currently, December is the cheapest month in which you can book a flight from Charlotte to Santiago (average of $696). Flying from Charlotte to Santiago in May is currently the most expensive (average of $1,025). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Charlotte to Santiago

Discover the top 3 airlines that operate flights from Charlotte to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$714Average$930FlexibilityNo cancel feeOn-time71%
DeltaCheapest$752Average$1,068FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$754Average$963FlexibilityNo cancel feeOn-time81%

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