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$311+ Cheap flights from Charlotte (CLT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — SCL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Charlotte Douglas to Santiago Arturo Merino Benitez are usually found in September or February, booked 36 days in advance, depart on a Wednesday or Tuesday and return on a Thursday

Cheap flight deals from Charlotte to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$617
(Kiwi.com)

One-way from

$311
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$828
From Charlotte Douglas to Santiago Arturo Merino Benitez
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One-way flight from Charlotte Douglas to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 7% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Charlotte to Santiago

Cheapest flights from Charlotte to Santiago
Explore the most affordable flight options available from Charlotte to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/21:50 pmCLT - SCL
2 stops31h 25mMultiple Airlines
Wed 10/1511:00 amSCL - CLT
1 stop26h 39mMultiple Airlines
Deal found 9/11$617
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:46 pmCLT - SCL
2 stops24h 44mMultiple Airlines
Sun 11/1611:25 pmSCL - CLT
1 stop24h 32mMultiple Airlines
Deal found 9/9$650
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/251:49 pmCLT - SCL
2 stops39h 01mMultiple Airlines
Sat 11/111:25 pmSCL - CLT
1 stop24h 32mMultiple Airlines
Deal found 9/10$657
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:00 amCLT - SCL
1 stop18h 55mLATAM Airlines
Tue 12/911:40 pmSCL - CLT
1 stop15h 48mLATAM Airlines
Deal found 9/10$703
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:12 pmCLT - SCL
2 stops14h 48mLATAM Airlines
Thu 12/1111:40 pmSCL - CLT
1 stop15h 48mLATAM Airlines
Deal found 9/10$707
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:05 amCLT - SCL
1 stop18h 40mLATAM Airlines
Wed 10/1510:55 pmSCL - CLT
1 stop15h 28mLATAM Airlines
Deal found 9/11$711
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/52:27 pmCLT - SCL
2 stops14h 33mLATAM Airlines
Tue 11/1111:40 pmSCL - CLT
1 stop15h 48mLATAM Airlines
Deal found 9/11$717

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Charlotte to Santiago that are best for you.

Fly from

Charlotte

Fly to

Santiago

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sat 11/8

9:49 am-5:30 am

2 stops17h 41m

Santiago Arturo Merino Benitez

Sat 11/15

1:35 am-4:01 pm

2 stops16h 26m

$659

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sat 10/25

5:45 am-5:30 am

2 stops22h 45m

Santiago Arturo Merino Benitez

Sat 11/1

4:25 pm-1:39 pm

2 stops22h 14m

$690

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 12/3

1:22 pm-6:55 am

1 stop15h 33m

Santiago Arturo Merino Benitez

Tue 12/9

11:40 pm-1:28 pm

1 stop15h 48m

$703

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 12/1

1:21 pm-6:55 am

1 stop15h 34m

Santiago Arturo Merino Benitez

Mon 12/15

8:20 am-11:48 pm

2 stops17h 28m

$703

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 11/5

2:27 pm-7:00 am

2 stops14h 33m

Santiago Arturo Merino Benitez

Tue 11/11

11:40 pm-1:28 pm

1 stop15h 48m

$717

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 11/26

2:12 pm-7:00 am

2 stops14h 48m

Santiago Arturo Merino Benitez

Mon 12/1

11:10 pm-6:26 pm

1 stop21h 16m

$723

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 9/30

10:46 am-5:15 am

2 stops17h 29m

Santiago Arturo Merino Benitez

Fri 10/10

3:30 pm-12:39 pm

2 stops22h 09m

$732

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 12/4

11:38 am-6:40 am

2 stops17h 02m

Santiago Arturo Merino Benitez

Tue 12/9

8:20 am-11:48 pm

2 stops17h 28m

$734

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 10/1

6:00 pm-2:25 pm

2 stops19h 25m

Santiago Arturo Merino Benitez

Tue 10/14

5:55 pm-1:42 pm

2 stops20h 47m

$734

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 10/29

5:50 pm-10:15 pm

3 stops51h 25m

$311

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 15 results
1
2

Best time to book a flight from Charlotte to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Santiago

How far ahead should I book a flight from Charlotte to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Charlotte to Santiago. Price data was last updated on August 29, 2025.

The price you pay for your flight from Charlotte to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Charlotte to Santiago?

Currently, April is the cheapest month in which you can book a flight from Charlotte to Santiago (average of $752). Flying from Charlotte to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to SCL?

Find hourly flight availability from Charlotte to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Charlotte to Santiago in the evening. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the morning.

How much does it cost to fly round-trip from Charlotte to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines, and American Airlines from Charlotte to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charlotte to Santiago?

    Airlines like LATAM Airlines fly from Charlotte to Santiago in about 15h 33m. The time it takes to get you to your destination can typically vary by up to . The distance from Charlotte to Santiago is about 4783 mi.

  • What are the cheapest airlines flying from Charlotte to Santiago round-trip?

    Cheapflights users have booked flights from Charlotte to Santiago round-trip from $748. Other airlines that can offer you cheap pricing are LATAM Airlines, from $754, and Delta, from $773. American Airlines is currently priced 20% below the average price you’ll pay for this route.

  • Can I find deals for flights from Charlotte to Santiago that include hotel bookings?

    Yes. In addition to deals on Charlotte to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Santiago.

  • Can I find deals for business class flights from Charlotte to Santiago?

    Yes. Cheapflights offers flight deals from Charlotte to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Charlotte to Santiago (average of $752). Flying from Charlotte to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Charlotte to Santiago

Discover the top 3 airlines that operate flights from Charlotte to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$748Average$967FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$754Average$971FlexibilityNo cancel feeOn-time81%
DeltaCheapest$773Average$1,068FlexibilityNo cancel feeOn-timeN/A

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