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$224+ Cheap flights from Cartagena (CTG) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
CTG — SCL
out 17 — out 241
sex 10/17
sex 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Cartagena Rafael Nunez to Santiago Arturo Merino Benitez are usually found in November or October, booked 62 days in advance, depart on a Monday or Tuesday and return on a Thursday

Cheap flight deals from Cartagena to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cartagena (CTG) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated setembro 17, 2025.

Round-trip from

$446
(JetSMART)

One-way from

$224
(JetSMART)

Popular in

February

Cheapest in

November

Average price

$505

Good one-way deal

$312 or less
From Cartagena Rafael Nunez to Santiago Arturo Merino Benitez
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One-way flight from Cartagena Rafael Nunez to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 6% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a one-way flight from Cartagena Rafael Nunez to Santiago Arturo Merino Benitez.
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Find flight deals from Cartagena to Santiago

Cheapest flights from Cartagena to Santiago
Explore the most affordable flight options available from Cartagena to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on setembro 17, 2025.

This JetSMART deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 12/251:54 pmCTG - SCL
1 stop13h 20mJetSMART
dom 1/49:29 pmSCL - CTG
1 stop23h 40mJetSMART
Deal found 9/17$446
This JetSMART deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 11/301:28 pmCTG - SCL
1 stop30h 53mJetSMART
seg 1/195:59 amSCL - CTG
1 stop15h 10mJetSMART
Deal found 9/16$467
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 11/106:24 amCTG - SCL
1 stop19h 00mCopa Airlines
qui 11/133:23 amSCL - CTG
1 stop9h 38mCopa Airlines
Deal found 9/15$472
This LATAM Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 11/711:27 amCTG - SCL
1 stop9h 23mLATAM Airlines
ter 11/114:35 amSCL - CTG
1 stop9h 30mLATAM Airlines
Deal found 9/17$473
This LATAM Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 11/1112:35 pmCTG - SCL
2 stops16h 00mLATAM Airlines
sáb 11/155:15 amSCL - CTG
2 stops15h 01mLATAM Airlines
Deal found 9/17$475
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 10/209:22 amCTG - SCL
1 stop8h 58mCopa Airlines
qui 2/191:16 amSCL - CTG
1 stop11h 45mCopa Airlines
Deal found 9/15$490

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cartagena to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated setembro 17, 2025.
Use the filters below to find and compare flights from Cartagena to Santiago that are best for you.

Fly from

Cartagena

Fly to

Santiago

Route

Depart

Return

Price

CartagenaSantiago

CTG - SCL

CTGSCL

Cartagena Rafael Nunez

qui 12/25

1:54 pm-5:14 am

1 stop13h 20m

Santiago Arturo Merino Benitez

dom 1/4

9:29 pm-7:09 pm

1 stop23h 40m

$446

CartagenaSantiago

CTG - SCL

CTGSCL

Cartagena Rafael Nunez

dom 11/30

1:28 pm-10:21 pm

1 stop30h 53m

Santiago Arturo Merino Benitez

seg 1/19

5:59 am-7:09 pm

1 stop15h 10m

$467

CartagenaSantiago

CTG - SCL

CTGSCL

Cartagena Rafael Nunez

qui 10/2

12:00 pm-12:04 am

1 stop10h 04m

Santiago Arturo Merino Benitez

qui 11/6

3:23 am-11:01 am

1 stop9h 38m

$472

CartagenaSantiago

CTG - SCL

CTGSCL

Cartagena Rafael Nunez

seg 11/10

6:24 am-3:24 am

1 stop19h 00m

Santiago Arturo Merino Benitez

qui 11/13

3:23 am-11:01 am

1 stop9h 38m

$472

CartagenaSantiago

CTG - SCL

CTGSCL

Cartagena Rafael Nunez

sex 10/17

6:20 am-8:20 pm

1 stop12h 00m

Santiago Arturo Merino Benitez

dom 10/26

12:20 pm-10:58 pm

1 stop12h 38m

$472

CartagenaSantiago

CTG - SCL

CTGSCL

Cartagena Rafael Nunez

qui 10/2

6:20 am-11:40 pm

1 stop15h 20m

Santiago Arturo Merino Benitez

qua 10/8

12:29 pm-11:00 pm

1 stop12h 31m

$472

CartagenaSantiago

CTG - SCL

CTGSCL

Cartagena Rafael Nunez

qua 10/1

12:00 pm-11:40 pm

1 stop9h 40m

Santiago Arturo Merino Benitez

qua 10/8

12:29 pm-11:00 pm

1 stop12h 31m

$472

CartagenaSantiago

CTG - SCL

CTGSCL

Cartagena Rafael Nunez

qua 10/15

9:42 am-12:04 am

1 stop12h 22m

Santiago Arturo Merino Benitez

qua 10/22

5:28 am-2:15 pm

1 stop10h 47m

$472

CartagenaSantiago

CTG - SCL

CTGSCL

Cartagena Rafael Nunez

seg 10/27

9:27 am-8:20 pm

1 stop8h 53m

Santiago Arturo Merino Benitez

ter 11/11

3:23 am-2:05 pm

1 stop12h 42m

$472

CartagenaSantiago

CTG - SCL

CTGSCL

Cartagena Rafael Nunez

qua 10/1

6:20 am-11:40 pm

1 stop15h 20m

Santiago Arturo Merino Benitez

dom 10/5

12:29 pm-11:00 pm

1 stop12h 31m

$472

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 18 results
1
2

Best time to book a flight from Cartagena to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cartagena with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cartagena to Santiago

How far ahead should I book a flight from Cartagena to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Cartagena to Santiago. Price data was last updated on September 12, 2025.

The price you pay for your flight from Cartagena to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Cartagena to Santiago?

Currently, April is the cheapest month in which you can book a flight from Cartagena to Santiago (average of $752). Flying from Cartagena to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated setembro 17, 2025.
Read through reviews of airlines operating flights from Cartagena to Santiago, such as Avianca and JetSMART. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Avianca
6.7
Okay
2,436 reviews

Entertainment

5.4

Food

5.1

Overall

6.7

Comfort

6.3

Crew

7.2

Boarding

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOG - LPB

no meals provided. Staff was nice. no entertainment behind seats
Avianca
6.7
Okay
2,436 reviews
Avianca
6.7
Okay
2,436 reviews

Entertainment

5.4

Food

5.1

Overall

6.7

Comfort

6.3

Crew

7.2

Boarding

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOG - LPB

no meals provided. Staff was nice. no entertainment behind seats
JetSMART
6.5
Okay
225 reviews
Avianca
6.7
Okay
2,436 reviews

Entertainment

5.4

Food

5.1

Overall

6.7

Comfort

6.3

Crew

7.2

Boarding

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOG - LPB

no meals provided. Staff was nice. no entertainment behind seats

Related info for your journey

Find useful and relevant information for your journey from Cartagena to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cartagena to Santiago?

    There are many flights that can get you from Cartagena to Santiago in 10h 04m. Fly via JetSMART or Copa Airlines to get the fastest option. The distance from Cartagena to Santiago is about 3043 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Cartagena to Santiago round-trip?

    Flying on Avianca is currently your cheapest option to Santiago, with prices starting at $325. Another option worth looking into is JetSMART, starting at $410 round trip. You may be able to fly from Cartagena to Santiago for 30% less than the average price by searching for these airlines.

  • What are the cheapest flights from Cartagena to Santiago?

    Looking for the cheapest flight from Cartagena to Santiago? While on average our users pay $313, our data indicates the cheapest price to be $312. The most popular route (Cartagena Rafael Nunez - Santiago Arturo Merino Benitez), is priced around $485.

  • Can I find deals for flights from Cartagena to Santiago that include hotel bookings?

    Yes. In addition to deals on Cartagena to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cartagena to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cartagena to Santiago.

  • Can I find deals for business class flights from Cartagena to Santiago?

    Yes. Cheapflights offers flight deals from Cartagena to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cartagena to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Cartagena to Santiago (average of $752). Flying from Cartagena to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Cartagena to Santiago

Discover the top 2 airlines that operate flights from Cartagena to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated setembro 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$325Average$709FlexibilityNo cancel feeOn-time71%
JetSMARTCheapest$410Average$532FlexibilityNo cancel feeOn-timeN/A

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