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$764+ Cheap flights from Buffalo (BUF) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SCL
Dec 12 — Dec 191
Fri 12/12
Fri 12/19
1 adult, Economy
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Find flight deals from Buffalo to Santiago

Cheapest flights from Buffalo to Santiago
Explore the most affordable flight options available from Buffalo to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2025.

This Expedia deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/212:10 pmBUF - SCL
1 stop17h 30mLATAM Airlines
Sun 12/710:25 pmSCL - BUF
2 stops27h 34mLATAM Airlines
Deal found 11/11$789
This LATAM Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/13:45 pmBUF - SCL
1 stop13h 10mLATAM Airlines
Sun 12/145:15 amSCL - BUF
2 stops20h 44mLATAM Airlines
Deal found 11/12$804
This Expedia deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:25 pmBUF - SCL
1 stop35h 15mLATAM Airlines
Fri 12/54:35 amSCL - BUF
2 stops21h 24mLATAM Airlines
Deal found 11/11$838
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2312:31 pmBUF - SCL
2 stops18h 29mAmerican Airlines
Sat 12/610:30 pmSCL - BUF
2 stops18h 37mAmerican Airlines
Deal found 11/11$849
This LATAM Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:10 amBUF - SCL
2 stops30h 10mMultiple Airlines
Sat 12/134:35 amSCL - BUF
2 stops18h 07mMultiple Airlines
Deal found 11/12$984
This FlightHub deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:49 pmBUF - SCL
1 stop13h 06mLATAM Airlines
Wed 12/319:30 pmSCL - BUF
1 stop17h 34mLATAM Airlines
Deal found 11/11$1,151

Cheap flight deals from Buffalo to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$764
(LATAM Airlines)
Provider with most accurate pricing for Buffalo-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Santiago Arturo Merino Benitez flights.
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From Buffalo to Santiago Arturo Merino Benitez
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 12, 2025.
Use the filters below to find and compare flights from Buffalo to Santiago that are best for you.

Fly from

Buffalo

Fly to

Santiago

Route

Depart

Return

Price

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Tue 2/10

6:00 am-2:20 pm

2 stops30h 20m

Santiago Arturo Merino Benitez

Wed 2/18

11:30 pm-9:09 pm

1 stop23h 39m

$764

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Tue 2/10

11:27 am-9:00 am

2 stops19h 33m

Santiago Arturo Merino Benitez

Wed 2/18

10:15 pm-3:26 pm

2 stops19h 11m

$769

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Tue 12/2

6:00 am-6:35 am

2 stops22h 35m

Santiago Arturo Merino Benitez

Sun 12/7

6:30 pm-11:04 am

2 stops18h 34m

$804

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Mon 12/1

3:45 pm-6:55 am

1 stop13h 10m

Santiago Arturo Merino Benitez

Sat 12/13

4:35 am-11:59 pm

2 stops21h 24m

$804

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Tue 12/2

3:55 pm-6:55 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Sat 12/6

4:35 am-11:59 pm

2 stops21h 24m

$829

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Sun 11/23

6:25 pm-7:40 am

1 stop35h 15m

Santiago Arturo Merino Benitez

Sat 12/6

5:15 am-11:59 pm

2 stops20h 44m

$838

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Compare providers for flights from Buffalo to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Santiago in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star
SmartFaresPrice Accuracy1 starTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated November 12, 2025.
Get a feel of what it's like to fly with LATAM Airlines from Buffalo to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,874 reviews

Comfort

7.3

Food

6.7

Entertainment

7.0

Overall

7.5

Crew

8.0

Boarding

7.6

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
LATAM Airlines
7.5
Good
1,874 reviews
LATAM Airlines
7.5
Good
1,874 reviews

Comfort

7.3

Food

6.7

Entertainment

7.0

Overall

7.5

Crew

8.0

Boarding

7.6

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santiago?

    American Airlines, Delta, and LATAM Airlines can get you from Buffalo to Santiago in just under 13h 10m. Your travel time can differ by up to 9h 25m. The distance between Buffalo and Santiago is about 5294 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Buffalo to Santiago round-trip?

    Flying on LATAM Airlines is currently your cheapest option to Santiago, with prices starting at $763.

  • Can I find deals for flights from Buffalo to Santiago that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santiago.

  • Can I find deals for business class flights from Buffalo to Santiago?

    Yes. Cheapflights offers flight deals from Buffalo to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Buffalo to Santiago

Discover the top airline that operate flights from Buffalo to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$763Average$1,251FlexibilityNo cancel feeOn-time81%

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