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Santander

$492+ Cheap flights from San Francisco (SFO) to Santander (SDR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDR
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from San Francisco to Santander

Cheapest flights from San Francisco to Santander
Explore the most affordable flight options available from San Francisco to Santander. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Rumbo deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:30 pm
SFO
-
SDR
2 stops18h 30m
Iberia
Sun 3/159:25 am
SDR
-
SFO
2 stops19h 48m
Iberia
Deal found 1/26$951
This Cheapflightsfares deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:50 pm
SFO
-
SDR
2 stops17h 00m
Iberia
Sun 9/209:20 am
SDR
-
SFO
2 stops17h 45m
Iberia
Deal found 1/26$1,207
This Iberia deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:15 am
SFO
-
SDR
2 stops17h 35m
Iberia
Tue 2/249:00 am
SDR
-
SFO
2 stops21h 16m
Iberia
Deal found 1/26$1,232
This Iberia deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:00 am
SFO
-
SDR
2 stops16h 45m
Iberia
Mon 7/65:40 pm
SDR
-
SFO
1 stop31h 40m
Iberia
Deal found 1/26$1,644
This Iberia deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:00 am
SFO
-
SDR
2 stops16h 45m
Iberia
Sat 7/49:20 am
SDR
-
SFO
1 stop16h 00m
Iberia
Deal found 1/26$1,649
This Iberia deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:55 pm
SFO
-
SDR
1 stop14h 05m
Iberia
Mon 7/65:40 pm
SDR
-
SFO
1 stop31h 40m
Iberia
Deal found 1/26$1,697
This Iberia deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:55 pm
SFO
-
SDR
1 stop14h 05m
Iberia
Sat 7/49:20 am
SDR
-
SFO
1 stop16h 00m
Iberia
Deal found 1/26$1,701
This Iberia deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:55 pm
SFO
-
SDR
1 stop18h 55m
Iberia
Sun 7/59:20 am
SDR
-
SFO
2 stops20h 36m
Iberia
Deal found 1/26$1,761
This Iberia deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:00 am
SFO
-
SDR
2 stops16h 45m
Iberia
Sun 7/55:40 pm
SDR
-
SFO
2 stops39h 18m
Iberia
Deal found 1/26$1,823

Find flight deals from San Francisco to Santander

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santander (SDR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Round-trip from

$951
(Rumbo)

One-way from

$492
(Trip.com)
From San Francisco to Santander
Search Deals
One-way flight from San Francisco to Santander
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Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Santander that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from San Francisco to Santander that are best for you.

Fly from

San Francisco

Fly to

Santander

Route

Depart

Return

Price

San FranciscoSantander

SFO - SDR

SFOSDR

San Francisco

Tue 3/10

6:30 pm-9:00 pm

2 stops18h 30m

Santander

Sun 3/15

9:25 am-9:13 pm

2 stops19h 48m

$951

San FranciscoSantander

SFO - SDR

SFOSDR

San Francisco

Fri 2/20

10:36 am-9:00 pm

2 stops25h 24m

Santander

Tue 2/24

9:00 am-11:59 pm

2 stops23h 59m

$1,232

San FranciscoSantander

SFO - SDR

SFOSDR

San Francisco

Fri 6/19

7:00 am-8:45 am

2 stops16h 45m

Santander

Mon 7/6

5:40 pm-4:20 pm

1 stop31h 40m

$1,644

San FranciscoSantander

SFO - SDR

SFOSDR

San Francisco

Fri 6/19

7:00 am-8:45 am

2 stops16h 45m

Santander

Sat 7/4

9:20 am-4:20 pm

1 stop16h 00m

$1,649

San FranciscoSantander

SFO - SDR

SFOSDR

San Francisco

Sat 6/20

5:55 pm-5:00 pm

1 stop14h 05m

Santander

Mon 7/6

5:40 pm-4:20 pm

1 stop31h 40m

$1,697

San FranciscoSantander

SFO - SDR

SFOSDR

San Francisco

Sat 6/20

5:55 pm-5:00 pm

1 stop14h 05m

Santander

Sat 7/4

9:20 am-4:20 pm

1 stop16h 00m

$1,701

San FranciscoSantander

SFO - SDR

SFOSDR

San Francisco

Sat 6/20

5:55 pm-9:50 pm

1 stop18h 55m

Santander

Sun 7/5

9:20 am-8:56 pm

2 stops20h 36m

$1,761

San FranciscoSantander

SFO - SDR

SFOSDR

San Francisco

Fri 6/19

7:00 am-8:45 am

2 stops16h 45m

Santander

Sun 7/5

5:40 pm-11:58 pm

2 stops39h 18m

$1,823

San FranciscoSantander

SFO - SDR

SFOSDR

San Francisco

Sat 5/23

7:35 pm-5:00 pm

2 stops36h 25m

$492

San FranciscoSantander

SFO - SDR

SFOSDR

San Francisco

Fri 5/22

8:20 pm-7:20 pm

3 stops38h 00m

$502

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 15 results
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Best time to book a flight from San Francisco to Santander

Have a flexible travel schedule? Discover the best time to fly to Santander from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santander

What is the cheapest month to book a flight from San Francisco to Santander?

Currently, March is the cheapest month in which you can book a flight from San Francisco to Santander (average of $396). Flying from San Francisco to Santander in June is currently the most expensive (average of $901). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santander. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Santander?

    Departing from San Francisco to Santander will take you 18h 30m. There are 5640 mi between San Francisco and Santander.

  • Can I find deals for flights from San Francisco to Santander that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santander flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santander?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santander.

  • Can I find deals for business class flights from San Francisco to Santander?

    Yes. Cheapflights offers flight deals from San Francisco to Santander by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santander?

    Currently, March is the cheapest month in which you can book a flight from San Francisco to Santander (average of $396). Flying from San Francisco to Santander in June is currently the most expensive (average of $901). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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