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$188+ Cheap flights from Mesa, AZ to Santa Fe (SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SAF
Dec 2 — Dec 91
Tue 12/2
Tue 12/9
1 adult, Economy
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Cheap flight deals from Mesa to Santa Fe

Keep the following information in mind while searching for Mesa to Santa Fe flight deals. Data was last updated November 2, 2025.

Round-trip from

$363
(American Airlines)

One-way from

$188
(American Airlines)

Popular in

November

Cheapest in

September

Average price

$626
From Mesa to Santa Fe
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One-way flight from Mesa to Santa Fe
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Highest demand for flights based on searches. 4% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Mesa to Santa Fe

Cheapest flights from Mesa to Santa Fe
Explore the most affordable flight options available from Mesa to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2025.

This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/61:32 pmPHX - SAF
Nonstop1h 23mAmerican Airlines
Sun 12/73:25 pmSAF - PHX
Nonstop1h 36mAmerican Airlines
Deal found 11/1$363
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/14:34 pmPHX - SAF
Nonstop1h 26mAmerican Airlines
Mon 12/81:16 pmSAF - PHX
1 stop19h 19mAmerican Airlines
Deal found 11/1$378
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/151:32 pmPHX - SAF
Nonstop1h 23mAmerican Airlines
Mon 12/226:50 pmSAF - PHX
Nonstop1h 42mAmerican Airlines
Deal found 10/31$394

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Mesa to Santa Fe that are best for you.

Fly from

Mesa

Fly to

Santa Fe

Route

Depart

Return

Price

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Sat 12/6

1:32 pm-2:55 pm

Nonstop1h 23m

Santa Fe

Sun 12/7

3:25 pm-5:01 pm

Nonstop1h 36m

$363

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Fri 1/16

4:33 pm-5:57 pm

Nonstop1h 24m

Santa Fe

Mon 1/19

12:14 pm-9:04 am

1 stop20h 50m

$378

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Mon 12/1

4:34 pm-6:00 pm

Nonstop1h 26m

Santa Fe

Mon 12/8

1:16 pm-8:35 am

1 stop19h 19m

$378

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Mon 12/15

1:32 pm-2:55 pm

Nonstop1h 23m

Santa Fe

Mon 12/22

6:50 pm-8:32 pm

Nonstop1h 42m

$394

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Thu 1/1

8:15 am-1:00 pm

1 stop4h 45m

$248

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Fri 1/30

8:50 am-11:43 am

1 stop26h 53m

$253

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Wed 12/31

8:15 pm-12:24 pm

2 stops16h 09m

$260

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Sat 1/31

7:59 pm-12:29 pm

2 stops16h 30m

$260

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Fri 1/30

4:36 pm-12:39 pm

2 stops20h 03m

$274

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Wed 2/11

3:07 pm-1:20 pm

1 stop22h 13m

$275

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/31

Showing 1-10 of 11 results
1
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Best time to book a flight from Mesa to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Santa Fe

What is the cheapest month to book a flight from Mesa to Santa Fe?

Currently, June is the cheapest month in which you can book a flight from Mesa to Santa Fe (average of $143). Flying from Mesa to Santa Fe in February is currently the most expensive (average of $212). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SAF?

Find hourly flight availability from Mesa to Santa Fe. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 2, 2025.

It’s optimal to fly from Mesa to Santa Fe in the morning. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight in the evening.

Weekly flight availability from Mesa to Santa Fe

Explore weekly flight availability from Mesa to Santa Fe. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 2, 2025.

The most flights from MS9 to SAF are scheduled on a Monday (3 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated November 2, 2025.
Read reviews from past customers who have flown American Airlines from Mesa to Santa Fe. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,037 reviews

Comfort

7.2

Food

6.4

Overall

7.2

Crew

8.0

Entertainment

6.9

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,037 reviews
American Airlines
7.2
Good
11,037 reviews

Comfort

7.2

Food

6.4

Overall

7.2

Crew

8.0

Entertainment

6.9

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Mesa to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from Mesa?

    For a flight from Mesa to Santa Fe, you will be flying into Santa Fe. Santa Fe (SAF) is just 9.8 mi from the center of the city. Santa Fe is the only Santa Fe airport and it handles 1 inbound flight from Mesa per day. 1 airline has flights to Santa Fe from Mesa on a regular basis.

  • How long is the flight from Mesa to Santa Fe?

    There are many flights that can get you from Mesa to Santa Fe in 1h 23m. Fly via American Airlines to get the fastest option. The distance between Mesa and Santa Fe is about 368 mi. Generally, flights for this route are nonstop.

  • What are the most reliable airlines from Mesa to Santa Fe?

    Consider SkyWest Airlines (85%), American Airlines (85%) or Porter Airlines (75%) when booking your flight. These represent the most reliable airlines when flying from Mesa to Santa Fe.

  • What are the cheapest flights from Mesa to Santa Fe?

    The cheapest flight price from Mesa to Santa Fe is $332. On average you can expect to pay $506. The most popular route, (Phoenix Sky Harbor Intl - Santa Fe), can usually be booked for $461.

  • Can I find deals for flights from Mesa to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Mesa to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Santa Fe.

  • Can I find deals for business class flights from Mesa to Santa Fe?

    Yes. Cheapflights offers flight deals from Mesa to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Santa Fe?

    Currently, June is the cheapest month in which you can book a flight from Mesa to Santa Fe (average of $143). Flying from Mesa to Santa Fe in February is currently the most expensive (average of $212). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Top airline flying from Mesa to Santa Fe

Discover the top airline that operate flights from Mesa to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$332Average$470FlexibilityNo cancel feeOn-time71%

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