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Santa Fe

$254+ Cheap flights from Mesa, AZ to Santa Fe (SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SAF
May 3 — May 101
Sun 5/3
Sun 5/10
1 adult, Economy
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Cheap flight deals from Mesa to Santa Fe

Cheapest flights from Mesa to Santa Fe
Explore the most affordable flight options available from Mesa to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.

This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:58 pm
PHX
-
SAF
1 stop17h 24m
American Airlines
Tue 5/511:56 am
SAF
-
PHX
1 stop10h 08m
American Airlines
Deal found 3/31$392
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:30 am
PHX
-
SAF
Nonstop1h 43m
American Airlines
Tue 11/33:25 pm
SAF
-
PHX
Nonstop1h 37m
American Airlines
Deal found 3/31$401
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:27 pm
PHX
-
SAF
Nonstop1h 28m
American Airlines
Sat 5/1611:56 am
SAF
-
PHX
1 stop9h 26m
American Airlines
Deal found 3/30$407
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:27 pm
PHX
-
SAF
Nonstop1h 28m
American Airlines
Sun 5/36:30 pm
SAF
-
PHX
Nonstop1h 40m
American Airlines
Deal found 3/30$435
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:30 pm
PHX
-
SAF
Nonstop1h 26m
American Airlines
Mon 5/183:26 pm
SAF
-
PHX
Nonstop1h 40m
American Airlines
Deal found 4/2$436
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:30 pm
PHX
-
SAF
Nonstop1h 26m
American Airlines
Sat 5/1611:56 am
SAF
-
PHX
1 stop9h 26m
American Airlines
Deal found 3/31$442
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:30 pm
PHX
-
SAF
Nonstop1h 26m
American Airlines
Wed 4/2211:56 am
SAF
-
PHX
1 stop10h 18m
American Airlines
Deal found 3/31$443

Find flight deals from Mesa to Santa Fe

Keep the following information in mind while searching for Mesa to Santa Fe flight deals. Data was last updated April 3, 2026.

Round-trip from

$392
(American Airlines)

One-way from

$254
(American Airlines)

Popular in

December

Cheapest in

July

Average price

$450
From Mesa to Santa Fe
Search Deals
One-way flight from Mesa to Santa Fe
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Mesa to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Thu 5/21

4:23 pm-6:48 pm

Nonstop1h 25m

Santa Fe

Sat 5/23

3:27 pm-4:05 pm

Nonstop1h 38m

$436

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Wed 5/13

12:27 pm-2:55 pm

Nonstop1h 28m

Santa Fe

Mon 5/18

11:56 am-6:07 pm

1 stop7h 11m

$446

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Sat 6/13

9:08 am-5:12 pm

1 stop7h 04m

Santa Fe

Thu 6/18

6:00 pm-9:59 pm

1 stop4h 59m

$490

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Tue 4/14

12:00 pm-5:08 pm

1 stop4h 08m

Santa Fe

Sat 4/18

10:24 am-4:54 pm

1 stop7h 30m

$492

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Mon 4/20

12:30 pm-2:56 pm

Nonstop1h 26m

Santa Fe

Sat 4/25

11:56 am-6:07 pm

1 stop7h 11m

$516

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Sat 5/9

9:50 am-2:50 pm

1 stop4h 00m

Santa Fe

Sat 5/16

5:49 pm-9:54 am

2 stops17h 05m

$547

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Wed 4/15

12:00 pm-5:08 pm

1 stop4h 08m

Santa Fe

Wed 4/22

5:49 pm-8:48 am

1 stop15h 59m

$560

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Thu 5/21

6:59 pm-9:44 am

1 stop13h 45m

Santa Fe

Sat 5/23

3:19 pm-8:30 pm

1 stop6h 11m

$588

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Tue 4/28

7:08 pm-5:06 pm

2 stops20h 58m

Santa Fe

Tue 5/5

5:49 pm-12:19 pm

2 stops19h 30m

$598

PhoenixSanta Fe

PHX - SAF

PHXSAF

Phoenix Sky Harbor Intl

Fri 4/17

6:00 am-12:44 pm

1 stop5h 44m

Santa Fe

Mon 4/20

5:49 pm-10:48 am

1 stop17h 59m

$606

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 23 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Mesa to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Santa Fe

What is the cheapest month to book a flight from Mesa to Santa Fe?

Currently, June is the cheapest month in which you can book a flight from Mesa to Santa Fe (average of $143). Flying from Mesa to Santa Fe in March is currently the most expensive (average of $213). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SAF?

Find hourly flight availability from Mesa to Santa Fe. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 3, 2026.

It’s optimal to fly from Mesa to Santa Fe at noon. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight in the evening.

How much does it cost to fly round-trip from Mesa to Santa Fe?

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated April 3, 2026.
Read reviews from past customers who have flown American Airlines from Mesa to Santa Fe. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,552 reviews

Entertainment

6.9

Crew

7.9

Comfort

7.2

Food

6.4

Boarding

7.5

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,552 reviews
American Airlines
7.1
Good
11,552 reviews

Entertainment

6.9

Crew

7.9

Comfort

7.2

Food

6.4

Boarding

7.5

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Mesa to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from Mesa?

    For a flight from Mesa to Santa Fe, you will be flying into Santa Fe. Santa Fe (SAF) is just 9.8 mi from the center of the city. Santa Fe is the only Santa Fe airport and it handles 1 inbound flight from Mesa per day. 1 airline has flights to Santa Fe from Mesa on a regular basis.

  • How long is the flight from Mesa to Santa Fe?

    There are many flights that can get you from Mesa to Santa Fe in 1h 25m. Fly via American Airlines or United Airlines to get the fastest option. The distance between Mesa and Santa Fe is about 368 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most reliable airlines from Mesa to Santa Fe?

    Consider SkyWest Airlines (84%), American Airlines (84%) or Alaska Airlines (80%) when booking your flight. These represent the most reliable airlines when flying from Mesa to Santa Fe.

  • What are the cheapest flights from Mesa to Santa Fe?

    The cheapest flight price from Mesa to Santa Fe is $362. On average you can expect to pay $439. The most popular route, (Phoenix Sky Harbor Intl - Santa Fe), can usually be booked for $432.

  • Can I find deals for flights from Mesa to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Mesa to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Santa Fe.

  • Can I find deals for business class flights from Mesa to Santa Fe?

    Yes. Cheapflights offers flight deals from Mesa to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Santa Fe?

    Currently, June is the cheapest month in which you can book a flight from Mesa to Santa Fe (average of $143). Flying from Mesa to Santa Fe in March is currently the most expensive (average of $213). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Top airline flying from Mesa to Santa Fe

Discover the top airline that operate flights from Mesa to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$332Average$432FlexibilityNo cancel feeOn-time71%

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