$273+ Cheap flights from Mesa, AZ to Santa Fe (SAF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/22. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SAF
Oct 8 — Oct 151
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to Santa Fe with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mesa to Santa Fe
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Best
Last-minute
One-way
Cheapest flights from Mesa to Santa FeExplore the most affordable flight options available from Mesa to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from Mesa to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:15 am -
1 stop9h 23m
Tue 11/36:18 pm -
1 stop18h 07m
Deal found 9/3![American Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:15 am -
1 stop9h 32m
Sun 11/156:18 pm -
1 stop14h 14m
Deal found 9/3![American Airlines logo]()
$455
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:00 am -
1 stop8h 38m
Wed 10/147:15 pm -
Nonstop1h 39m
Deal found 9/8![American Airlines logo]()
$460
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:15 am -
1 stop9h 34m
Sat 12/512:14 pm -
Nonstop1h 42m
Deal found 9/7![American Airlines logo]()
$490
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/299:31 am -
Nonstop1h 41m
Sat 1/211:42 am -
Nonstop1h 42m
Deal found 9/3![American Airlines logo]()
$494
Best flights from Mesa to Santa FeDiscover carefully curated flight deals from Mesa to Santa Fe that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from Mesa to Santa Fe that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:57 am -
Nonstop1h 29m
Tue 11/312:21 pm -
Nonstop1h 42m
Deal found 9/3![American Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:18 am -
1 stop6h 31m
Wed 12/305:46 pm -
1 stop4h 59m
Deal found 9/7![United Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:15 am -
1 stop9h 34m
Sat 12/512:14 pm -
Nonstop1h 42m
Deal found 9/7![American Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/54:30 pm -
1 stop4h 21m
Sat 1/91:20 pm -
1 stop4h 52m
Deal found 9/7![United Airlines logo]()
$563
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/124:30 pm -
1 stop5h 31m
Mon 2/153:20 pm -
1 stop5h 54m
Deal found 9/3![United Airlines logo]()
$563
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
2 stops13h 29m
Tue 11/31:26 pm -
1 stop6h 29m
Deal found 9/3![United Airlines logo]()
$584
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:10 am -
1 stop6h 35m
Sat 10/317:00 am -
2 stops14h 25m
Deal found 9/4![United Airlines logo]()
$623
Last-minute flights from Mesa to Santa FeDiscover last-minute flight deals from Mesa to Santa Fe. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Santa Fe. Data last updated September 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:30 am -
Nonstop1h 35m
Sat 9/2612:35 pm -
Nonstop1h 30m
Deal found 9/4![American Airlines logo]()
$506
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:57 am -
Nonstop1h 29m
Tue 10/1311:56 am -
Nonstop1h 30m
Deal found 9/6![American Airlines logo]()
$498
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:00 am -
1 stop8h 38m
Wed 10/147:15 pm -
Nonstop1h 39m
Deal found 9/8![American Airlines logo]()
$460
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:57 am -
Nonstop1h 29m
Thu 10/297:15 pm -
Nonstop1h 39m
Deal found 9/7![American Airlines logo]()
$499
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:15 am -
1 stop9h 23m
Tue 11/36:18 pm -
1 stop18h 07m
Deal found 9/3![American Airlines logo]()
$385
One-way flights from Mesa to Santa FeSearch for one-way flight options from Mesa to Santa Fe. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
Search for one-way flight options from Mesa to Santa Fe. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/229:54 am -
Nonstop1h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:05 pm -
1 stop27h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:29 pm -
2 stops17h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/59:24 pm -
1 stop15h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:43 pm -
2 stops19h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:59 pm -
2 stops13h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:51 am -
2 stops29h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$376
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:20 pm -
2 stops17h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/69:24 pm -
1 stop15h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:31 pm -
2 stops17h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$387
Find flight deals from Mesa to Santa Fe
Keep the following information in mind while searching for Mesa to Santa Fe flight deals. Data was last updated September 8, 2026.
Round-trip from | $385 (American Airlines) |
|---|---|
One-way from | $273 (American Airlines) |
Popular in | December |
Cheapest in | November |
Average price | $470 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from Mesa to Santa Fe that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixSanta Fe
PHX Phoenix Sky Harbor Intl - SAF Santa Fe
PHXSAF
Phoenix Sky Harbor Intl
Sat 10/3
4:00 pm-2:46 pm
2 stops21h 46m
Santa Fe
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$397
PhoenixSanta Fe
PHX Phoenix Sky Harbor Intl - SAF Santa Fe
PHXSAF
Phoenix Sky Harbor Intl
Tue 11/3
5:41 pm-9:12 am
1 stop15h 31m
Santa Fe
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$407
PhoenixSanta Fe
PHX Phoenix Sky Harbor Intl - SAF Santa Fe
PHXSAF
Phoenix Sky Harbor Intl
Thu 11/5
5:41 pm-9:45 am
1 stop16h 04m
Santa Fe
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$407
PhoenixSanta Fe
PHX Phoenix Sky Harbor Intl - SAF Santa Fe
PHXSAF
Phoenix Sky Harbor Intl
Tue 10/6
2:19 pm-9:55 pm
1 stop6h 36m
Santa Fe
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$418
PhoenixSanta Fe
PHX Phoenix Sky Harbor Intl - SAF Santa Fe
PHXSAF
Phoenix Sky Harbor Intl
Tue 3/2
9:50 am-2:49 pm
1 stop4h 59m
Santa Fe
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$418
PhoenixSanta Fe
PHX Phoenix Sky Harbor Intl - SAF Santa Fe
PHXSAF
Phoenix Sky Harbor Intl
Fri 10/30
5:20 am-5:10 pm
1 stop10h 50m
Santa Fe
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$425
PhoenixSanta Fe
PHX Phoenix Sky Harbor Intl - SAF Santa Fe
PHXSAF
Phoenix Sky Harbor Intl
Fri 10/2
4:15 pm-2:46 pm
3 stops21h 31m
Santa Fe
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$437
Quickest round-trip
PhoenixSanta Fe
PHX Phoenix Sky Harbor Intl - SAF Santa Fe
PHXSAF
Phoenix Sky Harbor Intl
Mon 3/1
1:35 pm-3:02 pm
Nonstop1h 27m
Santa Fe
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$438
PhoenixSanta Fe
PHX Phoenix Sky Harbor Intl - SAF Santa Fe
PHXSAF
Phoenix Sky Harbor Intl
Thu 3/4
4:36 pm-6:05 pm
Nonstop1h 29m
Santa Fe
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$438
PhoenixSanta Fe
PHX Phoenix Sky Harbor Intl - SAF Santa Fe
PHXSAF
Phoenix Sky Harbor Intl
Thu 10/1
9:10 am-4:59 pm
1 stop6h 49m
Santa Fe
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$448
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Mesa to Santa Fe
Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Mesa with our price prediction graph.
PHX-SAF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Santa Fe
MS9-SAF
PHX-SAF
What is the cheapest time of day to fly from MS9 to SAF?
Find hourly flight availability from Mesa to Santa Fe. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 8, 2026.
It’s optimal to fly from Mesa to Santa Fe at noon. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight in the evening.
How much does it cost to fly round-trip from Mesa to Santa Fe?
Airfare is typical for this route at the moment.
Mesa to Santa Fe flights typically cost between $416 and $622 in October.The cheapest round-trip price found within the last 5 days was $420 on American Airlines (Oct 31-Nov 3).
Reviews of airlines servicing Santa Fe
Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated September 8, 2026.
Read reviews from past customers who have flown American Airlines from Mesa to Santa Fe. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Boarding
7.5
Overall
7.1
Entertainment
6.8
Comfort
7.2
Crew
7.9
Reviews
1 / 20
4.0
OkayAmanda,Sep 2023
PHX - OGG
Food
6.4
Boarding
7.5
Overall
7.1
Entertainment
6.8
Comfort
7.2
Crew
7.9
Reviews
1 / 20
4.0
OkayAmanda,Sep 2023
PHX - OGG
Related info for your journey
Find useful and relevant information for your journey from Mesa to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santa Fe?
Book flights to Santa Fe if you plan to visit one of these locationsSanta Rosa
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Complete your trip
Complete your trip to Santa Fe by adding a car rental and/or hotel reservation to your travel itinerary.
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Mesa and Santa Fe flights
Browse other Mesa and Santa Fe flight options. Last updated on September 8, 2026.
Popular flight searches
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Other flights to Santa Fe
Explore flights to Santa Fe departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 8, 2026.
Mesa to Santa Fe flights
Consider these flights traveling from Mesa to Santa Fe.
Top airline flying from Mesa to Santa Fe
Discover the top airline that operate flights from Mesa to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$332 | Average$482 | FlexibilityNo cancel fee | On-time71% |