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$309+ Cheap flights from Durham, NC to Santa Fe (SAF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SAF
Nov 25 — Dec 21
Tue 11/25
Tue 12/2
1 adult, Economy
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Cheap flight deals from Durham to Santa Fe

Keep the following information in mind while searching for Durham to Santa Fe flight deals. Data was last updated October 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$284
(American Airlines)

Popular in

June

Cheapest in

January

Average price

$468
Provider with most accurate pricing for Raleigh-Durham-Santa Fe flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Santa Fe flights.
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From Durham to Santa Fe
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Highest demand for flights based on searches. 10% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Durham to Santa Fe

Cheapest flights from Durham to Santa Fe
Explore the most affordable flight options available from Durham to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2025.

This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/141:15 pmRDU - SAF
1 stop9h 06mAmerican Airlines
Mon 11/176:15 amSAF - RDU
1 stop6h 20mAmerican Airlines
Deal found 10/25$309
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/88:00 amRDU - SAF
1 stop6h 41mUnited Airlines
Wed 11/121:26 pmSAF - RDU
2 stops8h 15mUnited Airlines
Deal found 10/25$344
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:00 amRDU - SAF
1 stop6h 40mUnited Airlines
Mon 11/1710:48 amSAF - RDU
2 stops10h 53mUnited Airlines
Deal found 10/25$409
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/108:00 amRDU - SAF
1 stop6h 40mUnited Airlines
Fri 11/1410:48 amSAF - RDU
2 stops21h 25mUnited Airlines
Deal found 10/26$528
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:00 amRDU - SAF
1 stop6h 28mAmerican Airlines
Fri 11/1412:32 pmSAF - RDU
1 stop7h 40mAmerican Airlines
Deal found 10/26$592
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:00 amRDU - SAF
1 stop6h 28mAmerican Airlines
Fri 11/286:15 amSAF - RDU
1 stop6h 20mAmerican Airlines
Deal found 10/23$663
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:00 amRDU - SAF
2 stops8h 41mUnited Airlines
Fri 11/286:00 pmSAF - RDU
2 stops13h 28mUnited Airlines
Deal found 10/23$682

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 26, 2025.
Use the filters below to find and compare flights from Durham to Santa Fe that are best for you.

Fly from

Durham

Fly to

Santa Fe

Route

Depart

Return

Price

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Sat 11/8

8:00 am-12:41 pm

1 stop6h 41m

Santa Fe

Wed 11/12

1:26 pm-11:41 pm

2 stops8h 15m

$344

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Wed 4/8

4:00 pm-10:01 pm

1 stop8h 01m

Santa Fe

Tue 4/14

1:26 pm-11:05 pm

1 stop7h 39m

$374

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Tue 4/7

3:55 pm-8:01 pm

1 stop6h 06m

Santa Fe

Wed 4/15

6:21 am-3:26 pm

2 stops7h 05m

$385

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Sat 4/4

12:45 pm-10:01 pm

2 stops11h 16m

Santa Fe

Tue 4/14

10:45 am-11:10 pm

2 stops10h 25m

$389

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Sat 4/4

5:05 am-9:26 am

1 stop6h 21m

Santa Fe

Wed 4/8

5:05 pm-12:23 am

1 stop5h 18m

$399

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Tue 4/7

2:50 pm-10:01 pm

2 stops9h 11m

Santa Fe

Wed 4/15

10:45 am-9:02 pm

2 stops8h 17m

$400

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Tue 4/7

3:55 pm-8:01 pm

1 stop6h 06m

Santa Fe

Sat 4/18

5:05 pm-12:23 am

1 stop5h 18m

$414

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Fri 11/14

6:00 am-4:57 pm

2 stops12h 57m

Santa Fe

Mon 11/17

1:26 pm-11:41 pm

2 stops8h 15m

$414

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Fri 2/6

1:56 pm-9:09 pm

2 stops9h 13m

Santa Fe

Wed 2/11

10:28 am-9:34 pm

2 stops9h 06m

$433

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Fri 11/7

7:03 am-2:52 pm

1 stop9h 49m

$473

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 11 results
1
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Best time to book a flight from Durham to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santa Fe

What is the cheapest month to book a flight from Durham to Santa Fe?

Currently, August is the cheapest month in which you can book a flight from Durham to Santa Fe (average of $223). Flying from Durham to Santa Fe in June is currently the most expensive (average of $301). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SAF?

Find hourly flight availability from Durham to Santa Fe. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 26, 2025.

A simple way to save on the total cost of your ticket is to fly from Durham to Santa Fe in the afternoon. If you’re flexible enough to do this you can expect to save up to 24% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated October 26, 2025.
Read reviews from past customers who have flown American Airlines from Durham to Santa Fe. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,030 reviews

Boarding

7.5

Crew

8.0

Entertainment

6.9

Comfort

7.2

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,030 reviews
American Airlines
7.2
Good
11,030 reviews

Boarding

7.5

Crew

8.0

Entertainment

6.9

Comfort

7.2

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Durham to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from Durham?

    For a flight from Durham to Santa Fe, you will be flying into Santa Fe. Santa Fe (SAF) is just 9.8 mi from the center of the city. Santa Fe is the only Santa Fe airport and it handles 0 inbound flights from Durham per day. 1 airline has flights to Santa Fe from Durham on a regular basis.

  • How long is the flight from Durham to Santa Fe?

    Departing from Durham to Santa Fe will take you 6h 06m. Durham and Santa Fe are separated by a distance of 1525 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Durham to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Durham to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santa Fe.

  • Can I find deals for business class flights from Durham to Santa Fe?

    Yes. Cheapflights offers flight deals from Durham to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Santa Fe?

    Currently, August is the cheapest month in which you can book a flight from Durham to Santa Fe (average of $223). Flying from Durham to Santa Fe in June is currently the most expensive (average of $301). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Top airline flying from Durham to Santa Fe

Discover the top airline that operate flights from Durham to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$263Average$507FlexibilityNo cancel feeOn-time71%

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