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$222+ Cheap flights from Durham, NC to Santa Fe (SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SAF
sep. 8 — sep. 151
lun. 9/8
lun. 9/15
1 adult, Economy
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Cheap flight deals from Durham to Santa Fe

Keep the following information in mind while searching for Durham to Santa Fe flight deals. Data was last updated septiembre 3, 2025.

Round-trip from

$284
(American Airlines)

One-way from

$222
(United Airlines)

Popular in

June

Cheapest in

January

Average price

$483
From Durham to Santa Fe
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One-way flight from Durham to Santa Fe
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Highest demand for flights based on searches. 8% potential increase in price ($45 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Durham to Santa Fe

Cheapest flights from Durham to Santa Fe
Explore the most affordable flight options available from Durham to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 3, 2025.

This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/275:13 amRDU - SAF
1 stop6h 20mAmerican Airlines
mar. 9/306:15 amSAF - RDU
1 stop5h 42mAmerican Airlines
Deal found 9/3$284
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/178:08 amRDU - SAF
1 stop6h 38mAmerican Airlines
jue. 12/251:28 pmSAF - RDU
1 stop6h 25mAmerican Airlines
Deal found 9/2$324
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/141:15 pmRDU - SAF
1 stop9h 06mAmerican Airlines
lun. 11/176:15 amSAF - RDU
1 stop6h 20mAmerican Airlines
Deal found 9/2$349
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/254:20 pmRDU - SAF
2 stops7h 50mAmerican Airlines
sáb. 11/111:44 amSAF - RDU
2 stops8h 22mAmerican Airlines
Deal found 8/31$359
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/113:13 pmRDU - SAF
1 stop7h 48mAmerican Airlines
lun. 10/136:15 amSAF - RDU
1 stop6h 07mAmerican Airlines
Deal found 9/1$369
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/235:16 amRDU - SAF
1 stop6h 35mAmerican Airlines
lun. 10/276:15 amSAF - RDU
1 stop6h 07mAmerican Airlines
Deal found 9/3$414

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 3, 2025.
Use the filters below to find and compare flights from Durham to Santa Fe that are best for you.

Fly from

Durham

Fly to

Santa Fe

Route

Depart

Return

Price

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

sáb. 9/27

5:13 am-9:33 am

1 stop6h 20m

Santa Fe

mar. 9/30

6:15 am-1:57 pm

1 stop5h 42m

$284

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

vie. 11/14

5:00 am-9:28 am

1 stop6h 28m

Santa Fe

lun. 11/17

6:15 am-2:35 pm

1 stop6h 20m

$304

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

vie. 2/6

7:30 am-2:39 pm

1 stop9h 09m

Santa Fe

dom. 2/8

10:43 am-6:05 pm

1 stop5h 22m

$304

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

sáb. 10/25

11:47 am-4:29 pm

1 stop6h 42m

Santa Fe

sáb. 11/1

6:15 am-2:20 pm

1 stop6h 05m

$304

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

mié. 12/17

8:08 am-12:46 pm

1 stop6h 38m

Santa Fe

jue. 12/25

1:28 pm-9:53 pm

1 stop6h 25m

$324

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

jue. 12/25

5:01 am-12:18 pm

1 stop9h 17m

Santa Fe

mié. 12/31

1:28 pm-10:38 pm

1 stop7h 10m

$349

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

sáb. 9/13

7:00 am-5:09 pm

2 stops12h 09m

$222

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

sáb. 10/4

4:30 pm-10:03 pm

1 stop7h 33m

$388

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

sáb. 9/13

5:13 am-9:33 am

1 stop6h 20m

$410

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

lun. 9/15

4:28 pm-10:00 pm

1 stop7h 32m

$652

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/2

Best time to book a flight from Durham to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santa Fe

What is the cheapest month to book a flight from Durham to Santa Fe?

Currently, January is the cheapest month in which you can book a flight from Durham to Santa Fe (average of $372). Flying from Durham to Santa Fe in March is currently the most expensive (average of $537). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SAF?

Find hourly flight availability from Durham to Santa Fe. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 3, 2025.

When flying from Durham to Santa Fe, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Durham to Santa Fe?

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated septiembre 3, 2025.
Read reviews from past customers who have flown United Airlines and American Airlines from Durham to Santa Fe. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Food

6.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Food

6.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,937 reviews

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Food

6.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Durham to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from Durham?

    For a flight from Durham to Santa Fe, you will be flying into Santa Fe. Santa Fe (SAF) is just 9.8 mi from the center of the city. Santa Fe is the only Santa Fe airport and it handles 0 inbound flights from Durham per day. 2 airlines have flights to Santa Fe from Durham on a regular basis.

  • How long is the flight from Durham to Santa Fe?

    Departing from Durham to Santa Fe will take you 6h 20m. Durham and Santa Fe are separated by a distance of 1525 mi.

  • Can I find deals for flights from Durham to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Durham to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santa Fe.

  • Can I find deals for business class flights from Durham to Santa Fe?

    Yes. Cheapflights offers flight deals from Durham to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Santa Fe?

    Currently, January is the cheapest month in which you can book a flight from Durham to Santa Fe (average of $372). Flying from Durham to Santa Fe in March is currently the most expensive (average of $537). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Top 2 airlines flying from Durham to Santa Fe

Discover the top 2 airlines that operate flights from Durham to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$263Average$502FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$317Average$441FlexibilityNo cancel feeOn-time69%

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