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Santa Fe

$279+ Cheap flights from Durham, NC to Santa Fe (SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SAF
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Durham to Santa Fe

Cheapest flights from Durham to Santa Fe
Explore the most affordable flight options available from Durham to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:01 amRDU - SAF
1 stop6h 34mAmerican Airlines
Sun 1/44:43 pmSAF - RDU
1 stop5h 45mAmerican Airlines
Deal found 12/16$527
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:38 amRDU - SAF
1 stop7h 46mAmerican Airlines
Tue 12/306:15 amSAF - RDU
1 stop6h 18mAmerican Airlines
Deal found 12/17$556
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:31 amRDU - SAF
2 stops11h 31mUnited Airlines
Tue 12/307:00 amSAF - RDU
2 stops14h 46mUnited Airlines
Deal found 12/17$623
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:45 amRDU - SAF
2 stops8h 17mUnited Airlines
Sun 1/46:02 pmSAF - RDU
2 stops13h 37mUnited Airlines
Deal found 12/16$649
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:29 amRDU - SAF
2 stops10h 33mUnited Airlines
Sat 1/36:02 pmSAF - RDU
1 stop26h 57mUnited Airlines
Deal found 12/14$763
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:23 pmRDU - SAF
1 stop8h 35mAmerican Airlines
Sat 1/34:43 pmSAF - RDU
1 stop15h 57mAmerican Airlines
Deal found 12/14$943

Find flight deals from Durham to Santa Fe

Keep the following information in mind while searching for Durham to Santa Fe flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$304
(United Airlines)

One-way from

$279
(American Airlines)

Popular in

June

Cheapest in

October

Average price

$588
Provider with most accurate pricing for Raleigh-Durham-Santa Fe flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Santa Fe flights.
Search Deals
From Durham to Santa Fe
Search Deals
One-way flight from Durham to Santa Fe
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Durham to Santa Fe that are best for you.

Fly from

Durham

Fly to

Santa Fe

Route

Depart

Return

Price

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Tue 1/27

4:07 pm-8:47 pm

1 stop6h 40m

Santa Fe

Mon 2/2

3:30 pm-11:15 pm

1 stop5h 45m

$304

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Wed 1/14

1:56 pm-9:09 pm

2 stops9h 13m

Santa Fe

Wed 1/21

6:25 am-4:48 pm

1 stop8h 23m

$314

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Fri 2/20

7:00 am-3:02 pm

1 stop10h 02m

Santa Fe

Tue 2/24

6:15 am-2:56 pm

1 stop6h 41m

$329

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 1/1

4:14 pm-9:59 pm

1 stop7h 45m

Santa Fe

Sat 1/10

1:16 pm-11:15 pm

1 stop7h 59m

$329

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 4/23

5:13 am-9:26 am

1 stop6h 13m

Santa Fe

Mon 4/27

5:05 pm-12:23 am

1 stop5h 18m

$329

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 1/1

6:00 am-1:00 pm

1 stop9h 00m

Santa Fe

Wed 1/21

10:28 am-7:05 pm

1 stop6h 37m

$329

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Sun 3/8

7:00 am-2:48 pm

1 stop9h 48m

$279

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 2/5

5:10 am-9:57 am

1 stop6h 47m

$279

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 2/19

11:18 am-8:31 pm

2 stops11h 13m

$284

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 1/29

11:30 am-4:35 pm

1 stop7h 05m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 13 results
1
2

Best time to book a flight from Durham to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santa Fe

What is the cheapest month to book a flight from Durham to Santa Fe?

Currently, August is the cheapest month in which you can book a flight from Durham to Santa Fe (average of $223). Flying from Durham to Santa Fe in June is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SAF?

Find hourly flight availability from Durham to Santa Fe. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

A simple way to save on the total cost of your ticket is to fly from Durham to Santa Fe in the afternoon. If you’re flexible enough to do this you can expect to save up to 24% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated December 18, 2025.
Read reviews from past customers who have flown United Airlines and American Airlines from Durham to Santa Fe. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,091 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability
United Airlines
7.4
Good
9,091 reviews
United Airlines
7.4
Good
9,091 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability
American Airlines
7.2
Good
11,054 reviews
United Airlines
7.4
Good
9,091 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability

Related info for your journey

Find useful and relevant information for your journey from Durham to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from Durham?

    For a flight from Durham to Santa Fe, you will be flying into Santa Fe. Santa Fe (SAF) is just 9.8 mi from the center of the city. Santa Fe is the only Santa Fe airport and it handles 0 inbound flights from Durham per day. 2 airlines have flights to Santa Fe from Durham on a regular basis.

  • How long is the flight from Durham to Santa Fe?

    Departing from Durham to Santa Fe will take you 6h 40m. Durham and Santa Fe are separated by a distance of 1525 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Durham to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Durham to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santa Fe.

  • Can I find deals for business class flights from Durham to Santa Fe?

    Yes. Cheapflights offers flight deals from Durham to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Santa Fe?

    Currently, August is the cheapest month in which you can book a flight from Durham to Santa Fe (average of $223). Flying from Durham to Santa Fe in June is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Top 2 airlines flying from Durham to Santa Fe

Discover the top 2 airlines that operate flights from Durham to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$284Average$408FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$284Average$513FlexibilityNo cancel feeOn-time71%

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