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Santa Fe

$309+ Cheap flights from Durham, NC to Santa Fe (SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SAF
May 4 — May 111
Mon 5/4
Mon 5/11
1 adult, Economy
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Cheap flight deals from Durham to Santa Fe

Cheapest flights from Durham to Santa Fe
Explore the most affordable flight options available from Durham to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2026.

This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:20 am
RDU
-
SAF
1 stop6h 18m
American Airlines
Sat 5/307:18 pm
SAF
-
RDU
1 stop9h 16m
American Airlines
Deal found 3/31$326
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:20 am
RDU
-
SAF
1 stop6h 18m
American Airlines
Thu 6/117:18 pm
SAF
-
RDU
1 stop9h 16m
American Airlines
Deal found 3/30$345
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:09 pm
RDU
-
SAF
2 stops9h 58m
American Airlines
Sat 5/26:15 am
SAF
-
RDU
1 stop6h 45m
American Airlines
Deal found 4/1$355
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:30 am
RDU
-
SAF
1 stop9h 02m
American Airlines
Sat 8/158:40 am
SAF
-
RDU
1 stop7h 56m
American Airlines
Deal found 3/31$375
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:16 am
RDU
-
SAF
1 stop6h 25m
American Airlines
Tue 8/1112:30 pm
SAF
-
RDU
1 stop6h 36m
American Airlines
Deal found 3/31$378
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:00 pm
RDU
-
SAF
1 stop8h 42m
American Airlines
Tue 6/166:05 am
SAF
-
RDU
1 stop7h 54m
American Airlines
Deal found 4/4$384
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:50 pm
RDU
-
SAF
1 stop7h 17m
American Airlines
Fri 4/242:04 pm
SAF
-
RDU
1 stop6h 33m
American Airlines
Deal found 3/31$389
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:30 am
RDU
-
SAF
1 stop9h 02m
American Airlines
Tue 8/1110:20 am
SAF
-
RDU
1 stop8h 46m
American Airlines
Deal found 3/31$403
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:00 am
RDU
-
SAF
1 stop9h 06m
American Airlines
Sat 4/1812:36 pm
SAF
-
RDU
1 stop6h 34m
American Airlines
Deal found 3/30$414
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:15 am
RDU
-
SAF
2 stops10h 53m
United Airlines
Sat 4/183:24 pm
SAF
-
RDU
1 stop5h 55m
United Airlines
Deal found 3/30$420

Find flight deals from Durham to Santa Fe

Keep the following information in mind while searching for Durham to Santa Fe flight deals. Data was last updated April 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$326
(American Airlines)

One-way from

$309
(American Airlines)

Popular in

March

Cheapest in

January

Average price

$374
Provider with most accurate pricing for Raleigh-Durham-Santa Fe flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Santa Fe flights.
Search Deals
From Durham to Santa Fe
Search Deals
One-way flight from Durham to Santa Fe
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($9 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from Durham to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Wed 5/27

6:00 am-5:12 pm

2 stops13h 12m

Santa Fe

Sat 5/30

1:22 pm-12:50 am

2 stops9h 28m

$479

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 7/2

8:00 am-2:44 pm

2 stops8h 44m

Santa Fe

Thu 7/9

1:22 pm-12:51 am

2 stops9h 29m

$532
Quickest round-trip

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Tue 4/21

4:18 pm-9:13 pm

1 stop6h 55m

Santa Fe

Tue 4/28

3:24 pm-11:19 pm

1 stop5h 55m

$570

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Sat 4/18

4:18 pm-8:38 pm

1 stop6h 20m

Santa Fe

Sun 4/26

1:19 pm-11:19 pm

1 stop8h 00m

$603

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Tue 4/14

8:15 am-5:08 pm

2 stops10h 53m

Santa Fe

Sat 4/18

10:24 am-9:23 pm

2 stops8h 59m

$633

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Sat 8/8

10:32 am-9:44 am

3 stops25h 12m

Santa Fe

Tue 8/11

3:21 pm-11:36 pm

1 stop6h 15m

$673
Cheapest one-way

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Fri 5/8

5:00 am-12:06 pm

1 stop9h 06m

$309
Quickest one-way

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 5/14

5:00 am-10:07 am

1 stop7h 07m

$309

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 4/23

7:00 am-5:08 pm

2 stops12h 08m

$364

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 5/14

6:20 am-2:50 pm

2 stops10h 30m

$505

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Sorted by cheapest first

Best time to book a flight from Durham to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santa Fe

What is the cheapest month to book a flight from Durham to Santa Fe?

Currently, August is the cheapest month in which you can book a flight from Durham to Santa Fe (average of $223). Flying from Durham to Santa Fe in February is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Durham to Santa Fe?

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated April 4, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Durham to Santa Fe. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,542 reviews

Entertainment

7.1

Comfort

7.3

Crew

8.1

Food

6.6

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,542 reviews
United Airlines
7.4
Good
9,542 reviews

Entertainment

7.1

Comfort

7.3

Crew

8.1

Food

6.6

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.1
Good
11,559 reviews
United Airlines
7.4
Good
9,542 reviews

Entertainment

7.1

Comfort

7.3

Crew

8.1

Food

6.6

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Durham to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from Durham?

    For a flight from Durham to Santa Fe, you will be flying into Santa Fe. Santa Fe (SAF) is just 9.8 mi from the center of the city. Santa Fe is the only Santa Fe airport and it handles 0 inbound flights from Durham per day. 2 airlines have flights to Santa Fe from Durham on a regular basis.

  • How long is the flight from Durham to Santa Fe?

    Departing from Durham to Santa Fe will take you 13h 12m. Durham and Santa Fe are separated by a distance of 1525 mi.

  • Can I find deals for flights from Durham to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Durham to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santa Fe.

  • Can I find deals for business class flights from Durham to Santa Fe?

    Yes. Cheapflights offers flight deals from Durham to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Santa Fe?

    Currently, August is the cheapest month in which you can book a flight from Durham to Santa Fe (average of $223). Flying from Durham to Santa Fe in February is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Top 2 airlines flying from Durham to Santa Fe

Discover the top 2 airlines that operate flights from Durham to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$264Average$500FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$284Average$400FlexibilityNo cancel feeOn-time69%

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