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Santa Cruz de la Sierra

$503+ Cheap flights from Santo Domingo (SDQ) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — VVI
Feb 21 — Feb 281
Sat 2/21
Sat 2/28
1 adult, Economy
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Cheap flight deals from Santo Domingo to Santa Cruz de la Sierra

Cheapest flights from Santo Domingo to Santa Cruz de la Sierra
Explore the most affordable flight options available from Santo Domingo to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 22, 2026.

This Copa Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:48 am
SDQ
-
VVI
1 stop13h 52m
Copa Airlines
Sat 7/181:12 am
VVI
-
SDQ
1 stop10h 30m
Copa Airlines
Deal found 1/20$770
This Copa Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/232:11 pm
SDQ
-
VVI
1 stop13h 33m
Copa Airlines
Thu 1/291:15 am
VVI
-
SDQ
1 stop10h 17m
Copa Airlines
Deal found 1/22$778
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/47:25 pm
SDQ
-
VVI
2 stops33h 10m
Multiple Airlines
Tue 3/33:40 am
VVI
-
SDQ
1 stop19h 20m
Multiple Airlines
Deal found 1/21$1,107
This Copa Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/42:11 pm
SDQ
-
VVI
1 stop8h 39m
Copa Airlines
Tue 3/31:14 am
VVI
-
SDQ
1 stop9h 34m
Copa Airlines
Deal found 1/21$1,208
This Copa Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/232:11 pm
SDQ
-
VVI
1 stop13h 33m
Copa Airlines
Sun 1/251:15 am
VVI
-
SDQ
1 stop10h 17m
Copa Airlines
Deal found 1/21$1,210
This Copa Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/217:05 pm
SDQ
-
VVI
1 stop8h 39m
Copa Airlines
Tue 1/271:15 am
VVI
-
SDQ
1 stop16h 50m
Copa Airlines
Deal found 1/20$1,214
This Avianca Connect deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/215:45 pm
SDQ
-
VVI
1 stop8h 50m
Avianca
Tue 1/273:40 am
VVI
-
SDQ
1 stop13h 10m
Avianca
Deal found 1/20$1,909

Find flight deals from Santo Domingo to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$1,107
(Kiwi.com)

One-way from

$503
(Avianca)

Popular in

May

Cheapest in

April

Average price

$679
Provider with most accurate pricing for Santo Domingo Las Americas-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Santo Domingo Las Americas to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Santo Domingo Las Americas to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($53 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from Santo Domingo to Santa Cruz de la Sierra that are best for you.

Fly from

Santo Domingo

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

Santo DomingoSanta Cruz de la Sierra

SDQ - VVI

SDQVVI

Santo Domingo Las Americas

Sun 7/12

8:48 am-10:40 pm

1 stop13h 52m

Santa Cruz de la Sierra Viru Viru Intl

Sat 7/18

1:12 am-11:42 am

1 stop10h 30m

$770

Santo DomingoSanta Cruz de la Sierra

SDQ - VVI

SDQVVI

Santo Domingo Las Americas

Wed 2/4

7:25 pm-4:35 am

2 stops33h 10m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/3

3:40 am-11:00 pm

1 stop19h 20m

$1,107

Santo DomingoSanta Cruz de la Sierra

SDQ - VVI

SDQVVI

Santo Domingo Las Americas

Wed 2/4

2:11 pm-10:50 pm

1 stop8h 39m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/3

1:14 am-10:48 am

1 stop9h 34m

$1,208

Santo DomingoSanta Cruz de la Sierra

SDQ - VVI

SDQVVI

Santo Domingo Las Americas

Thu 1/29

12:20 pm-2:35 am

1 stop14h 15m

$503

Santo DomingoSanta Cruz de la Sierra

SDQ - VVI

SDQVVI

Santo Domingo Las Americas

Tue 1/27

12:20 pm-2:35 am

1 stop14h 15m

$503

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

  • Most accurate provider: When it comes to deals on Santo Domingo-Santa Cruz de la Sierra flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-Santa Cruz de la Sierra flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Santa Cruz de la Sierra flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Santa Cruz de la Sierra

How far ahead should I book a flight from Santo Domingo to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Santa Cruz de la Sierra. Price data was last updated on January 16, 2026.

The price you pay for your flight from Santo Domingo to Santa Cruz de la Sierra may vary depending on when you book. For the best chance of a lower fare, look to book 28 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santo Domingo to Santa Cruz de la Sierra?

Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Santa Cruz de la Sierra (average of $293). Flying from Santo Domingo to Santa Cruz de la Sierra in August is currently the most expensive (average of $665). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santo Domingo to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated January 22, 2026.
See what other customers who have flown with Avianca from Santo Domingo to Santa Cruz de la Sierra have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Avianca
6.6
Okay
2,496 reviews

Entertainment

5.4

Food

5.0

Overall

6.6

Boarding

6.9

Crew

7.2

Comfort

6.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOG - LPB

no meals provided. Staff was nice. no entertainment behind seats
Avianca
6.6
Okay
2,496 reviews
Avianca
6.6
Okay
2,496 reviews

Entertainment

5.4

Food

5.0

Overall

6.6

Boarding

6.9

Crew

7.2

Comfort

6.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOG - LPB

no meals provided. Staff was nice. no entertainment behind seats

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Santa Cruz de la Sierra?

    There are many flights that can get you from Santo Domingo to Santa Cruz de la Sierra in 13h 52m. Fly via Copa Airlines to get the fastest option. Santo Domingo and Santa Cruz de la Sierra are separated by a distance of 2530 mi.

  • What is the cheapest airline to fly from Santo Domingo to Santa Cruz de la Sierra round-trip?

    Avianca, at $284, was found to be the cheapest airline from Santo Domingo to Santa Cruz de la Sierra.. Avianca is 60% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santo Domingo to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Santo Domingo to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Santo Domingo to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Santa Cruz de la Sierra?

    Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Santa Cruz de la Sierra (average of $293). Flying from Santo Domingo to Santa Cruz de la Sierra in August is currently the most expensive (average of $665). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.
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Top airline flying from Santo Domingo to Santa Cruz de la Sierra

Discover the top airline that operate flights from Santo Domingo to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$284Average$737FlexibilityNo cancel feeOn-time71%

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