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Santa Cruz de la Sierra

$668+ Cheap flights from Santo Domingo (SDQ) to Santa Cruz de la Sierra (VVI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — VVI
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Santa Cruz de la Sierra Viru Viru Intl are usually found in April or May, booked 29 days in advance, depart on a Monday or Wednesday and return on a Tuesday

Find flight deals from Santo Domingo to Santa Cruz de la Sierra

Cheapest flights from Santo Domingo to Santa Cruz de la Sierra
Explore the most affordable flight options available from Santo Domingo to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Copa Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:39 pmSDQ - VVI
1 stop8h 57mCopa Airlines
Sat 11/1511:40 amVVI - SDQ
1 stop14h 46mCopa Airlines
Deal found 11/5$668
This Copa Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/272:15 pmSDQ - VVI
1 stop8h 31mCopa Airlines
Sat 11/291:09 amVVI - SDQ
1 stop12h 03mCopa Airlines
Deal found 11/5$696
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:55 amSDQ - VVI
1 stop18h 41mCopa Airlines
Tue 12/91:09 amVVI - SDQ
1 stop21h 47mCopa Airlines
Deal found 11/5$718
This Copa Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:39 pmSDQ - VVI
1 stop8h 57mCopa Airlines
Fri 12/121:09 amVVI - SDQ
1 stop15h 06mCopa Airlines
Deal found 11/5$769
This Copa Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:15 pmSDQ - VVI
1 stop8h 31mCopa Airlines
Sat 12/131:09 amVVI - SDQ
1 stop10h 31mCopa Airlines
Deal found 11/5$782
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:45 pmSDQ - VVI
1 stop8h 50mMultiple Airlines
Wed 12/105:25 amVVI - SDQ
2 stops20h 15mMultiple Airlines
Deal found 11/5$875

Cheap flight deals from Santo Domingo to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$668
(Copa Airlines)

Popular in

December

Cheapest in

April

Average price

$625
Provider with most accurate pricing for Santo Domingo Las Americas-Santa Cruz de la Sierra Viru Viru Intl flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Santo Domingo Las Americas to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($85 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Santo Domingo to Santa Cruz de la Sierra that are best for you.

Fly from

Santo Domingo

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

Santo DomingoSanta Cruz de la Sierra

SDQ - VVI

SDQVVI

Santo Domingo Las Americas

Wed 4/15

12:40 pm-10:50 pm

1 stop10h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/20

11:44 am-2:17 am

1 stop14h 33m

$668

Santo DomingoSanta Cruz de la Sierra

SDQ - VVI

SDQVVI

Santo Domingo Las Americas

Wed 12/3

8:55 am-3:36 am

1 stop18h 41m

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/9

1:09 am-10:56 pm

1 stop21h 47m

$718

Santo DomingoSanta Cruz de la Sierra

SDQ - VVI

SDQVVI

Santo Domingo Las Americas

Sat 12/6

12:40 pm-10:46 pm

1 stop10h 06m

Santa Cruz de la Sierra Viru Viru Intl

Fri 12/12

1:09 am-4:15 pm

1 stop15h 06m

$769

Santo DomingoSanta Cruz de la Sierra

SDQ - VVI

SDQVVI

Santo Domingo Las Americas

Thu 3/26

2:13 pm-10:50 pm

1 stop8h 37m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/30

12:15 pm-2:18 am

1 stop14h 03m

$779

Santo DomingoSanta Cruz de la Sierra

SDQ - VVI

SDQVVI

Santo Domingo Las Americas

Wed 12/3

5:45 pm-2:35 am

1 stop8h 50m

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/10

5:25 am-1:40 am

2 stops20h 15m

$875

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Compare providers for flights from Santo Domingo to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Santa Cruz de la Sierra in November.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Santa Cruz de la Sierra flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santo Domingo-Santa Cruz de la Sierra flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santo Domingo-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Santa Cruz de la Sierra flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Santa Cruz de la Sierra

How far ahead should I book a flight from Santo Domingo to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Santa Cruz de la Sierra. Price data was last updated on October 31, 2025.

The price you pay for your flight from Santo Domingo to Santa Cruz de la Sierra may vary depending on when you book. For the best chance of a lower fare, look to book 28 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santo Domingo to Santa Cruz de la Sierra?

Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Santa Cruz de la Sierra (average of $293). Flying from Santo Domingo to Santa Cruz de la Sierra in August is currently the most expensive (average of $665). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santo Domingo to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated November 6, 2025.
See what other customers who have flown with Avianca from Santo Domingo to Santa Cruz de la Sierra have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Avianca
6.6
Okay
2,469 reviews

Crew

7.2

Food

5.1

Overall

6.6

Boarding

7.0

Entertainment

5.4

Comfort

6.3

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOG - LPB

no meals provided. Staff was nice. no entertainment behind seats
Avianca
6.6
Okay
2,469 reviews
Avianca
6.6
Okay
2,469 reviews

Crew

7.2

Food

5.1

Overall

6.6

Boarding

7.0

Entertainment

5.4

Comfort

6.3

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOG - LPB

no meals provided. Staff was nice. no entertainment behind seats

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Santa Cruz de la Sierra?

    There are many flights that can get you from Santo Domingo to Santa Cruz de la Sierra in 10h 10m. Fly via Copa Airlines to get the fastest option. Santo Domingo and Santa Cruz de la Sierra are separated by a distance of 2530 mi.

  • What is the cheapest airline to fly from Santo Domingo to Santa Cruz de la Sierra round-trip?

    Avianca, at $505, was found to be the cheapest airline from Santo Domingo to Santa Cruz de la Sierra.. Avianca is 23% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santo Domingo to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Santo Domingo to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Santo Domingo to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Santa Cruz de la Sierra?

    Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Santa Cruz de la Sierra (average of $293). Flying from Santo Domingo to Santa Cruz de la Sierra in August is currently the most expensive (average of $665). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.
Santa Cruz de la Sierra car rentals
Santa Cruz de la Sierra Viru Viru Intl Airport car rentals
La Paz car rentals
Cochabamba car rentals
Tarija car rentals

Top airline flying from Santo Domingo to Santa Cruz de la Sierra

Discover the top airline that operate flights from Santo Domingo to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$505Average$606FlexibilityNo cancel feeOn-time71%

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