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Santa Cruz de la Sierra

$617+ Cheap flights from San Francisco (SFO) to Santa Cruz de la Sierra (VVI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — VVI
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from San Francisco to Santa Cruz de la Sierra

Cheapest flights from San Francisco to Santa Cruz de la Sierra
Explore the most affordable flight options available from San Francisco to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/151:35 amSFO - VVI
2 stops21h 00mAvianca
Sat 11/223:40 amVVI - SFO
2 stops22h 10mAvianca
Deal found 10/26$617
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/134:15 pmSFO - VVI
2 stops26h 31mUnited Airlines
Thu 11/2011:40 amVVI - SFO
2 stops23h 44mUnited Airlines
Deal found 10/28$638
This United deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2712:43 amSFO - VVI
2 stops18h 57mMultiple Airlines
Mon 11/33:40 amVVI - SFO
2 stops17h 07mMultiple Airlines
Deal found 10/27$643
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2712:43 amSFO - VVI
2 stops18h 57mUnited Airlines
Tue 11/411:40 amVVI - SFO
2 stops23h 55mUnited Airlines
Deal found 10/27$645
This Copa Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/271:36 amSFO - VVI
1 stop18h 04mCopa Airlines
Tue 11/411:40 amVVI - SFO
1 stop15h 37mCopa Airlines
Deal found 10/27$657
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/511:10 pmSFO - VVI
2 stops23h 25mAvianca
Sun 11/163:40 amVVI - SFO
2 stops22h 10mAvianca
Deal found 10/27$688
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:10 pmSFO - VVI
2 stops23h 25mAvianca
Sun 11/233:40 amVVI - SFO
2 stops22h 10mAvianca
Deal found 10/27$689
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/61:20 pmSFO - VVI
2 stops33h 15mAvianca
Mon 11/173:40 amVVI - SFO
2 stops22h 10mAvianca
Deal found 10/27$697
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1212:36 amSFO - VVI
1 stop18h 10mCopa Airlines
Mon 11/2411:40 amVVI - SFO
1 stop15h 37mCopa Airlines
Deal found 10/28$698
This Justfly.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/163:35 pmSFO - VVI
2 stops33h 00mLATAM Airlines
Sun 11/2310:43 amVVI - SFO
2 stops31h 52mLATAM Airlines
Deal found 10/26$815
This FlightHub deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:20 pmSFO - VVI
2 stops33h 15mAvianca
Wed 11/193:40 amVVI - SFO
2 stops22h 10mAvianca
Deal found 10/28$840

Cheap flight deals from San Francisco to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$568
(Cheapflightsfares)

Popular in

December

Cheapest in

March

Average price

$776
Provider with most accurate pricing for San Francisco-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From San Francisco to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($94 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from San Francisco to Santa Cruz de la Sierra that are best for you.

Fly from

San Francisco

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 11/13

2:49 pm-10:46 pm

2 stops27h 57m

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/24

11:40 am-9:36 am

2 stops25h 56m

$638

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 11/13

11:44 pm-3:36 am

2 stops23h 52m

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/20

11:40 am-7:35 am

2 stops23h 55m

$638

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sun 3/1

12:43 am-2:35 am

2 stops45h 52m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

11:44 am-7:30 pm

2 stops34h 46m

$663

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sat 2/14

4:10 pm-10:50 pm

2 stops26h 40m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/7

11:42 am-8:39 am

2 stops24h 57m

$675

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Fri 2/27

7:00 am-10:50 pm

2 stops35h 50m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

11:44 am-7:30 pm

2 stops34h 46m

$702

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 3/5

9:30 pm-10:50 pm

2 stops21h 20m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

11:44 am-7:30 pm

2 stops34h 46m

$702

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sat 2/28

12:43 am-3:38 am

2 stops22h 55m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

11:44 am-7:30 pm

2 stops34h 46m

$702

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 3/3

6:50 pm-10:50 pm

2 stops24h 00m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

11:44 am-7:30 pm

2 stops34h 46m

$702

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sun 3/1

10:40 pm-10:50 pm

2 stops20h 10m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

11:44 am-9:05 am

2 stops24h 21m

$712

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Compare providers for flights from San Francisco to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santa Cruz de la Sierra in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Santa Cruz de la Sierra flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Santa Cruz de la Sierra flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Santa Cruz de la Sierra flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santa Cruz de la Sierra

What is the cheapest month to book a flight from San Francisco to Santa Cruz de la Sierra?

Currently, April is the cheapest month in which you can book a flight from San Francisco to Santa Cruz de la Sierra (average of $353). Flying from San Francisco to Santa Cruz de la Sierra in July is currently the most expensive (average of $921). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to VVI?

Find hourly flight availability from San Francisco to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

It’s optimal to fly from San Francisco to Santa Cruz de la Sierra in the morning. By choosing this option you can save up to 56% on the cost of your flight, compared to a flight in the evening.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated October 28, 2025.
Get a feel of what it's like to fly with Copa Airlines, United Airlines, and Avianca from San Francisco to Santa Cruz de la Sierra by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,560 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,560 reviews
Copa Airlines
7.6
Good
1,560 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
8,996 reviews
Copa Airlines
7.6
Good
1,560 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,468 reviews
Copa Airlines
7.6
Good
1,560 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Santa Cruz de la Sierra?

    For as low as $638, United Airlines can have you in Santa Cruz de la Sierra from San Francisco in 27h 57m. The distance from San Francisco to Santa Cruz de la Sierra is about 5414 mi.

  • What are the cheapest airlines flying from San Francisco to Santa Cruz de la Sierra round-trip?

    Cheapflights users have booked flights from San Francisco to Santa Cruz de la Sierra round-trip from $585. Other airlines that can offer you cheap pricing are Copa Airlines, from $622, and United Airlines, from $644. Avianca is priced at 33% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Francisco to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from San Francisco to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from San Francisco to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santa Cruz de la Sierra?

    Currently, April is the cheapest month in which you can book a flight from San Francisco to Santa Cruz de la Sierra (average of $353). Flying from San Francisco to Santa Cruz de la Sierra in July is currently the most expensive (average of $921). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from San Francisco to Santa Cruz de la Sierra

Discover the top 3 airlines that operate flights from San Francisco to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$585Average$816FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$622Average$985FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$644Average$965FlexibilityNo cancel feeOn-time69%

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