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Santa Cruz de la Sierra

$299+ Cheap flights from San Francisco (SFO) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/26. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — VVI
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheap flight deals from San Francisco to Santa Cruz de la Sierra

Cheapest flights from San Francisco to Santa Cruz de la Sierra
Explore the most affordable flight options available from San Francisco to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This Justfly.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/2211:10 pmSFO - VVI
2 stops47h 25mAvianca
dom. 1/43:40 amVVI - SFO
2 stops47h 40mAvianca
Deal found 12/10$2,337
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/201:35 amSFO - VVI
2 stops21h 00mAvianca
sáb. 1/33:40 amVVI - SFO
2 stops22h 10mAvianca
Deal found 12/10$2,505
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/228:45 amSFO - VVI
1 stop14h 51mUnited Airlines
lun. 1/511:44 amVVI - SFO
2 stops26h 39mUnited Airlines
Deal found 12/11$3,976
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/2112:36 amSFO - VVI
1 stop23h 00mCopa Airlines
dom. 1/41:15 amVVI - SFO
1 stop23h 14mCopa Airlines
Deal found 12/10$4,343
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/218:16 pmSFO - VVI
2 stops28h 19mMultiple Airlines
sáb. 1/31:15 amVVI - SFO
1 stop26h 05mMultiple Airlines
Deal found 12/10$4,423

Find flight deals from San Francisco to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated diciembre 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$638
(United Airlines)

One-way from

$299
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$1,667
Provider with most accurate pricing for San Francisco-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Santa Cruz de la Sierra Viru Viru Intl flights.
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From San Francisco to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from San Francisco to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($214 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($66 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from San Francisco to Santa Cruz de la Sierra that are best for you.

Fly from

San Francisco

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

vie. 1/30

10:35 pm-10:50 pm

2 stops20h 15m

Santa Cruz de la Sierra Viru Viru Intl

mar. 2/3

11:44 am-10:57 pm

2 stops39h 13m

$638

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

mar. 2/3

9:20 pm-3:44 am

2 stops26h 24m

Santa Cruz de la Sierra Viru Viru Intl

mar. 2/17

11:44 am-11:10 pm

2 stops39h 26m

$638

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

lun. 2/2

12:42 am-10:50 pm

1 stop18h 08m

Santa Cruz de la Sierra Viru Viru Intl

lun. 2/16

1:15 am-11:20 pm

1 stop26h 05m

$841

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

vie. 1/2

8:45 am-10:50 pm

1 stop34h 05m

Santa Cruz de la Sierra Viru Viru Intl

mar. 2/3

11:44 am-5:19 pm

2 stops33h 35m

$1,018

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

vie. 1/2

8:45 am-10:50 pm

1 stop34h 05m

Santa Cruz de la Sierra Viru Viru Intl

jue. 2/5

11:44 am-7:49 am

2 stops24h 05m

$1,018

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

jue. 1/1

12:42 am-3:44 am

1 stop23h 02m

Santa Cruz de la Sierra Viru Viru Intl

sáb. 2/7

11:44 am-5:19 pm

2 stops33h 35m

$1,018

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

dom. 1/4

8:45 am-3:44 am

1 stop14h 59m

Santa Cruz de la Sierra Viru Viru Intl

sáb. 2/7

11:44 am-5:19 pm

2 stops33h 35m

$1,018

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

vie. 12/26

11:05 pm-10:46 pm

2 stops43h 41m

$299

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

dom. 12/28

6:00 am-10:46 pm

2 stops36h 46m

$311

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

mié. 12/24

11:59 pm-10:46 pm

2 stops42h 47m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 13 results
1
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Compare providers for flights from San Francisco to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santa Cruz de la Sierra in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Santa Cruz de la Sierra flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Santa Cruz de la Sierra flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Santa Cruz de la Sierra flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santa Cruz de la Sierra

What is the cheapest month to book a flight from San Francisco to Santa Cruz de la Sierra?

Currently, June is the cheapest month in which you can book a flight from San Francisco to Santa Cruz de la Sierra (average of $353). Flying from San Francisco to Santa Cruz de la Sierra in July is currently the most expensive (average of $921). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to VVI?

Find hourly flight availability from San Francisco to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 12, 2025.

It’s optimal to fly from San Francisco to Santa Cruz de la Sierra in the morning. By choosing this option you can save up to 56% on the cost of your flight, compared to a flight in the evening.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated diciembre 12, 2025.
Get a feel of what it's like to fly with Copa Airlines, United Airlines, and Avianca from San Francisco to Santa Cruz de la Sierra by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,558 reviews

Food

6.9

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.6

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,558 reviews
Copa Airlines
7.6
Good
1,558 reviews

Food

6.9

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.6

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
9,095 reviews
Copa Airlines
7.6
Good
1,558 reviews

Food

6.9

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.6

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,480 reviews
Copa Airlines
7.6
Good
1,558 reviews

Food

6.9

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.6

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Santa Cruz de la Sierra?

    For as low as $841, United Airlines can have you in Santa Cruz de la Sierra from San Francisco in 18h 08m. The distance from San Francisco to Santa Cruz de la Sierra is about 5414 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Francisco to Santa Cruz de la Sierra round-trip?

    Cheapflights users have booked flights from San Francisco to Santa Cruz de la Sierra round-trip from $622. Other airlines that can offer you cheap pricing are United Airlines, from $637, and Avianca, from $640. Copa Airlines is priced at 34% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Francisco to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from San Francisco to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from San Francisco to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santa Cruz de la Sierra?

    Currently, June is the cheapest month in which you can book a flight from San Francisco to Santa Cruz de la Sierra (average of $353). Flying from San Francisco to Santa Cruz de la Sierra in July is currently the most expensive (average of $921). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to Santa Cruz de la Sierra

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Top 3 airlines flying from San Francisco to Santa Cruz de la Sierra

Discover the top 3 airlines that operate flights from San Francisco to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$622Average$897FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$637Average$1,075FlexibilityNo cancel feeOn-time69%
AviancaCheapest$640Average$892FlexibilityNo cancel feeOn-time71%

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