Santa Ana

$74+ Cheap flights from Florida Keys to Santa Ana, CA (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SNA
Jan 22 — Jan 291
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Cheap flight deals from Florida Keys to Santa Ana

Cheapest flights from Florida Keys to Santa Ana
Explore the most affordable flight options available from Florida Keys to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This Frontier deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:05 amMIA - SNA
1 stop14h 17mFrontier
Wed 12/3111:53 amSNA - MIA
1 stop14h 07mFrontier
Deal found 12/22$383
This CheapOair deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:05 amMIA - SNA
1 stop14h 17mFrontier
Sat 12/276:55 pmSNA - MIA
1 stop7h 40mFrontier
Deal found 12/20$388
This CheapOair deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:05 amMIA - SNA
1 stop15h 16mFrontier
Sat 12/276:55 pmSNA - MIA
1 stop7h 40mFrontier
Deal found 12/20$408
This Frontier deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:05 amMIA - SNA
1 stop14h 17mFrontier
Sun 1/47:57 pmSNA - MIA
1 stop6h 38mFrontier
Deal found 12/21$412
This CheapOair deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:05 amMIA - SNA
1 stop8h 03mFrontier
Sun 12/287:57 pmSNA - MIA
1 stop6h 38mFrontier
Deal found 12/21$413
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:05 amMIA - SNA
1 stop30h 11mMultiple Airlines
Sun 1/47:57 pmSNA - MIA
2 stops42h 22mMultiple Airlines
Deal found 12/21$436
This CheapOair deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:05 amMIA - SNA
1 stop14h 05mFrontier
Sun 12/287:57 pmSNA - MIA
1 stop6h 38mFrontier
Deal found 12/22$443

Find flight deals from Florida Keys to Santa Ana

Keep the following information in mind while searching for Florida Keys to Santa Ana flight deals. Data was last updated December 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$183
(CheapOair)

One-way from

$74
(Kiwi.com)
Provider with most accurate pricing for Key West-Los Angeles flight deals.
Provider most trusted by Cheapflights users for Key West-Los Angeles flights.
From Florida Keys to Santa Ana J. Wayne/Orange Cnty
One-way flight from Florida Keys to Santa Ana J. Wayne/Orange Cnty

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Florida Keys to Santa Ana that are best for you.

Fly from

Florida Keys

Fly to

Santa Ana

Route

Depart

Return

Price

MiamiSanta Ana

MIA - SNA

MIASNA

Miami

Fri 1/23

5:37 pm-10:19 am

1 stop19h 42m

Santa Ana J. Wayne/Orange Cnty

Mon 1/26

7:30 am-4:27 pm

1 stop29h 57m

$247

MiamiSanta Ana

MIA - SNA

MIASNA

Miami

Fri 1/23

5:37 pm-10:19 am

1 stop19h 42m

Santa Ana J. Wayne/Orange Cnty

Wed 1/28

11:15 am-5:28 am

2 stops15h 13m

$252

MiamiSanta Ana

MIA - SNA

MIASNA

Miami

Wed 1/21

5:37 pm-10:18 pm

1 stop31h 41m

Santa Ana J. Wayne/Orange Cnty

Mon 1/26

11:15 am-5:28 am

2 stops15h 13m

$252

MiamiSanta Ana

MIA - SNA

MIASNA

Miami

Thu 1/22

6:43 am-4:34 pm

2 stops12h 51m

Santa Ana J. Wayne/Orange Cnty

Tue 1/27

5:30 pm-4:27 pm

1 stop19h 57m

$252

MiamiSanta Ana

MIA - SNA

MIASNA

Miami

Thu 1/22

10:33 am-10:18 pm

2 stops14h 45m

Santa Ana J. Wayne/Orange Cnty

Thu 1/29

11:15 am-5:28 am

2 stops15h 13m

$258

MiamiSanta Ana

MIA - SNA

MIASNA

Miami

Thu 2/26

5:59 pm-9:12 pm

1 stop30h 13m

Santa Ana J. Wayne/Orange Cnty

Sat 2/28

6:45 am-4:59 pm

1 stop31h 14m

$276

MiamiSanta Ana

MIA - SNA

MIASNA

Miami

Thu 1/22

3:25 pm-10:15 pm

1 stop9h 50m

Santa Ana J. Wayne/Orange Cnty

Mon 1/26

7:30 am-5:28 am

2 stops18h 58m

$303

MiamiSanta Ana

MIA - SNA

MIASNA

Miami

Sat 1/17

9:26 pm-8:57 pm

3 stops26h 31m

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

4:37 pm-5:59 pm

2 stops22h 22m

$307

MiamiSanta Ana

MIA - SNA

MIASNA

Miami

Thu 1/22

10:33 am-10:18 pm

2 stops14h 45m

Santa Ana J. Wayne/Orange Cnty

Sun 1/25

7:10 pm-5:28 am

1 stop7h 18m

$323

MiamiSanta Ana

MIA - SNA

MIASNA

Miami

Thu 1/22

6:34 pm-10:27 pm

1 stop30h 53m

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

8:15 am-5:34 pm

1 stop30h 19m

$326

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 31 results
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Best time to book a flight from Florida Keys to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Santa Ana
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated December 23, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Florida Keys to Santa Ana have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santa Ana from Florida Keys?

    Santa Ana J. Wayne/Orange Cnty (SNA), located 4.8 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Santa Ana.

  • How long is the flight from Florida Keys to Santa Ana, California?

    Departing from Florida Keys to Santa Ana, California will take you 9h. Florida Keys and Santa Ana, California are separated by a distance of 2254 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Florida Keys to Santa Ana, California one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $96. Spirit Airlines flights start at $109 while deals on American Airlines start at $168 one-way.

  • Can I find deals for flights from Florida Keys to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Santa Ana.

  • Can I find deals for business class flights from Florida Keys to Santa Ana?

    Yes. Cheapflights offers flight deals from Florida Keys to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Tustin

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Alternative routes for Florida Keys to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Florida Keys to Santa Ana

Discover the top 3 airlines that operate flights from Florida Keys to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$338Average$498FlexibilityNo cancel feeOn-time71%
DeltaCheapest$373Average$518FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$447Average$449FlexibilityNo cancel feeOn-time69%

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