$124+ Cheap flights from Sioux Falls to San Francisco (FSD - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — SFO
Dec 10 — Dec 171
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to San Francisco
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Cheapest flights from Sioux Falls to San FranciscoExplore the most affordable flight options available from Sioux Falls to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
Explore the most affordable flight options available from Sioux Falls to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:10 pm -
1 stop14h 24m
Thu 12/102:17 pm -
1 stop19h 09m
Deal found 11/8![Multiple Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop7h 25m
Sat 12/1212:41 pm -
1 stop7h 36m
Deal found 11/5![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:26 pm -
1 stop7h 17m
Sat 12/124:03 pm -
1 stop5h 56m
Deal found 11/8![American Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:45 am -
1 stop7h 48m
Sat 12/54:42 pm -
1 stop5h 02m
Deal found 11/9![United Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:39 pm -
1 stop19h 43m
Fri 12/114:33 pm -
2 stops20h 13m
Deal found 11/9![Multiple Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:21 pm -
1 stop7h 09m
Thu 12/106:38 am -
1 stop8h 49m
Deal found 11/6![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:01 am -
2 stops11h 17m
Mon 12/1411:39 pm -
1 stop8h 33m
Deal found 11/5![Delta logo]()
$427
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:55 am -
1 stop5h 34m
Tue 11/245:00 am -
1 stop7h 23m
Deal found 11/5![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:59 pm -
2 stops12h 44m
Sat 12/126:00 am -
1 stop8h 20m
Deal found 11/8![Delta logo]()
$444
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:05 am -
1 stop7h 55m
Mon 11/2311:35 pm -
1 stop8h 45m
Deal found 11/5![Delta logo]()
$449
Best flights from Sioux Falls to San FranciscoDiscover carefully curated flight deals from Sioux Falls to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
Discover carefully curated flight deals from Sioux Falls to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2812:40 pm -
1 stop22h 09m
Sun 1/316:30 pm -
1 stop24h 16m
Deal found 11/7![Multiple Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop7h 25m
Sat 12/1212:41 pm -
1 stop7h 36m
Deal found 11/5![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/118:23 am -
1 stop6h 26m
Sat 2/136:00 am -
1 stop8h 19m
Deal found 11/8![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:40 am -
1 stop7h 35m
Mon 12/1412:41 pm -
1 stop7h 31m
Deal found 11/5![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:01 am -
2 stops11h 17m
Mon 12/1411:39 pm -
1 stop8h 33m
Deal found 11/5![Delta logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:06 pm -
1 stop15h 40m
Thu 12/102:22 pm -
2 stops19h 04m
Deal found 11/6![Multiple Airlines logo]()
$481
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:59 pm -
2 stops12h 44m
Sat 12/126:00 am -
1 stop8h 20m
Deal found 11/8![Delta logo]()
$444
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:12 am -
1 stop7h 38m
Tue 12/82:17 pm -
1 stop7h 13m
Deal found 11/6![United Airlines logo]()
$479
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:05 am -
1 stop7h 55m
Mon 11/2311:35 pm -
1 stop8h 45m
Deal found 11/5![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:50 am -
1 stop5h 47m
Wed 12/3011:30 pm -
1 stop9h 09m
Deal found 11/8![United Airlines logo]()
$489
Last-minute flights from Sioux Falls to San FranciscoDiscover last-minute flight deals from Sioux Falls to San Francisco. Data last updated November 10, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to San Francisco. Data last updated November 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:21 pm -
1 stop7h 09m
Thu 12/106:38 am -
1 stop8h 49m
Deal found 11/6![American Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:55 am -
1 stop5h 34m
Tue 11/245:00 am -
1 stop7h 23m
Deal found 11/5![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:05 am -
1 stop7h 55m
Mon 11/2311:35 pm -
1 stop8h 45m
Deal found 11/5![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:45 am -
1 stop7h 48m
Sat 12/54:42 pm -
1 stop5h 02m
Deal found 11/9![United Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop7h 25m
Sat 12/1212:41 pm -
1 stop7h 36m
Deal found 11/5![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:26 pm -
1 stop7h 17m
Sat 12/124:03 pm -
1 stop5h 56m
Deal found 11/8![American Airlines logo]()
$375
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:59 pm -
2 stops12h 44m
Sat 12/126:00 am -
1 stop8h 20m
Deal found 11/8![Delta logo]()
$444
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:39 pm -
1 stop19h 43m
Fri 12/114:33 pm -
2 stops20h 13m
Deal found 11/9![Multiple Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:10 pm -
1 stop14h 24m
Thu 12/102:17 pm -
1 stop19h 09m
Deal found 11/8![Multiple Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:01 am -
2 stops11h 17m
Mon 12/1411:39 pm -
1 stop8h 33m
Deal found 11/5![Delta logo]()
$427
One-way flights from Sioux Falls to San FranciscoSearch for one-way flight options from Sioux Falls to San Francisco. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
Search for one-way flight options from Sioux Falls to San Francisco. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1712:40 pm -
1 stop21h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:37 pm -
1 stop21h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:17 pm -
1 stop7h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$229
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:31 am -
1 stop5h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/254:39 pm -
1 stop17h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:38 am -
3 stops51h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$341
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:12 am -
1 stop9h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/78:15 am -
1 stop6h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Delta logo]()
$349
Find flight deals from Sioux Falls to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $333 (Kiwi.com) |
One-way from | $124 (Kiwi.com) |
Popular in | February |
Cheapest in | April |
Average price | $548 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
Use the filters below to find and compare flights from Sioux Falls to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Sun 1/17
12:40 pm-7:43 am
1 stop21h 03m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$124
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Tue 11/24
8:31 am-12:22 pm
1 stop5h 51m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$238
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Fri 12/25
4:39 pm-7:39 am
1 stop17h 00m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$302
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Thu 1/28
12:40 pm-8:49 am
1 stop22h 09m
San Francisco
Sun 1/31
6:30 pm-8:46 pm
1 stop24h 16m
$333
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Thu 12/3
10:38 am-12:00 pm
3 stops51h 22m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$341
Quickest round-trip
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Thu 12/17
5:50 am-9:37 am
1 stop5h 47m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$349
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Sun 3/7
8:15 am-12:31 pm
1 stop6h 16m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$349
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Wed 12/16
6:00 am-11:25 am
1 stop7h 25m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$349
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Wed 12/9
12:59 pm-8:18 pm
2 stops9h 19m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$356
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Sat 12/5
6:00 am-11:25 am
1 stop7h 25m
San Francisco
Sat 12/12
12:41 pm-10:17 pm
1 stop7h 36m
$369
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to San Francisco in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Sioux Falls with our price prediction graph.
FSD-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to San Francisco
What is the cheapest month to book a flight from Sioux Falls to San Francisco?
Currently, April is the cheapest month in which you can book a flight from Sioux Falls to San Francisco (average of $286). Flying from Sioux Falls to San Francisco in February is currently the most expensive (average of $708). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sioux Falls to San Francisco?
Airfare is below average for this route at the moment.
Sioux Falls to San Francisco flights typically cost between $490 and $588 in January.The cheapest round-trip price found within the last 5 days was $333 on Multiple Airlines (Jan 28-Jan 31).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated November 10, 2026.
Read through reviews of airlines operating flights from Sioux Falls to San Francisco, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Entertainment
7.8
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Entertainment
7.8
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Entertainment
7.8
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Hayward
Emeryville
Newark
Burlingame
San Bruno
Rancho Cordova
Vallejo
Cupertino
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Sioux Falls and San Francisco flights
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Top 3 airlines flying from Sioux Falls to San Francisco
Discover the top 3 airlines that operate flights from Sioux Falls to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$416 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$523 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$310 | Average$414 | FlexibilityNo cancel fee | On-timeN/A |