$111+ Cheap flights from Sioux Falls to San Francisco (FSD - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — SFO
Sep 14 — Sep 211
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to San Francisco
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Cheapest flights from Sioux Falls to San FranciscoExplore the most affordable flight options available from Sioux Falls to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 15, 2026.
Explore the most affordable flight options available from Sioux Falls to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 15, 2026.
This Frontier deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:31 pm -
1 stop6h 44m
Mon 10/266:00 am -
1 stop10h 36m
Deal found 8/11![Frontier logo]()
$231
This Frontier deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:56 pm -
1 stop5h 22m
Mon 9/76:00 am -
1 stop12h 01m
Deal found 8/13![Frontier logo]()
$240
This Frontier deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:56 pm -
1 stop5h 22m
Mon 8/316:00 am -
1 stop12h 01m
Deal found 8/10![Frontier logo]()
$255
This Frontier deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:52 pm -
1 stop5h 22m
Fri 9/2511:42 am -
1 stop6h 25m
Deal found 8/12![Frontier logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:52 pm -
2 stops23h 32m
Mon 9/286:04 am -
1 stop12h 03m
Deal found 8/12![Frontier logo]()
$288
This Expedia deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:56 pm -
1 stop5h 22m
Fri 8/286:00 am -
1 stop12h 01m
Deal found 8/13![Frontier logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:41 pm -
1 stop27h 09m
Fri 10/306:15 am -
1 stop11h 38m
Deal found 8/14![Multiple Airlines logo]()
$297
This Orbitz deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:08 pm -
1 stop6h 10m
Mon 8/176:00 am -
1 stop11h 23m
Deal found 8/10![Frontier logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:28 pm -
1 stop29h 04m
Mon 10/266:00 am -
1 stop10h 36m
Deal found 8/12![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:31 pm -
1 stop17h 34m
Sun 10/1810:06 pm -
1 stop12h 32m
Deal found 8/12![Multiple Airlines logo]()
$326
Best flights from Sioux Falls to San FranciscoDiscover carefully curated flight deals from Sioux Falls to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 15, 2026.
Discover carefully curated flight deals from Sioux Falls to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 15, 2026.
This Frontier deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:52 pm -
1 stop5h 22m
Fri 9/2511:42 am -
1 stop6h 25m
Deal found 8/10![Frontier logo]()
$240
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:05 am -
1 stop7h 56m
Wed 10/284:00 pm -
1 stop5h 58m
Deal found 8/13![American Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:50 pm -
1 stop6h 05m
Sun 9/61:54 pm -
1 stop7h 28m
Deal found 8/12![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:00 pm -
2 stops8h 56m
Mon 10/268:59 pm -
2 stops11h 01m
Deal found 8/13![Delta logo]()
$534
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop7h 25m
Tue 12/82:25 pm -
1 stop6h 31m
Deal found 8/10![United Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:52 pm -
2 stops8h 47m
Mon 10/265:30 am -
1 stop9h 53m
Deal found 8/13![American Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:50 pm -
1 stop6h 05m
Sat 9/511:30 pm -
1 stop8h 59m
Deal found 8/12![United Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:00 pm -
2 stops8h 56m
Mon 10/268:59 pm -
2 stops11h 01m
Deal found 8/12![Delta logo]()
$563
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:00 pm -
2 stops8h 56m
Wed 10/2810:35 am -
2 stops10h 47m
Deal found 8/13![Delta logo]()
$569
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:41 pm -
1 stop7h 49m
Fri 9/257:10 pm -
2 stops19h 13m
Deal found 8/11![United Airlines logo]()
$583
Last-minute flights from Sioux Falls to San FranciscoDiscover last-minute flight deals from Sioux Falls to San Francisco. Data last updated August 15, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to San Francisco. Data last updated August 15, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:56 pm -
1 stop5h 22m
Fri 8/286:00 am -
1 stop12h 01m
Deal found 8/13![Frontier logo]()
$295
This Frontier deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:56 pm -
1 stop5h 22m
Mon 8/316:00 am -
1 stop12h 01m
Deal found 8/10![Frontier logo]()
$255
This Frontier deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:56 pm -
1 stop5h 22m
Mon 9/76:00 am -
1 stop12h 01m
Deal found 8/13![Frontier logo]()
$240
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:50 pm -
1 stop6h 05m
Sun 9/61:54 pm -
1 stop7h 28m
Deal found 8/12![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:52 pm -
1 stop29h 22m
Mon 9/1411:42 am -
1 stop6h 25m
Deal found 8/10![Frontier logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:52 pm -
1 stop15h 55m
Sun 9/204:31 pm -
2 stops25h 36m
Deal found 8/12![Frontier logo]()
$361
This Frontier deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:52 pm -
1 stop5h 22m
Fri 9/2511:42 am -
1 stop6h 25m
Deal found 8/12![Frontier logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:52 pm -
2 stops23h 32m
Mon 9/286:04 am -
1 stop12h 03m
Deal found 8/12![Frontier logo]()
$288
One-way flights from Sioux Falls to San FranciscoSearch for one-way flight options from Sioux Falls to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 15, 2026.
Search for one-way flight options from Sioux Falls to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 15, 2026.
This Frontier deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:31 pm -
1 stop6h 44m
Deal found 8/12![Frontier logo]()
$111
This Expedia deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:56 pm -
1 stop5h 22m
Deal found 8/10![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:52 pm -
2 stops20h 54m
Deal found 8/11![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:48 pm -
1 stop27h 58m
Deal found 8/11![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:02 pm -
1 stop14h 53m
Deal found 8/11![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2412:58 pm -
1 stop28h 34m
Deal found 8/13![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:06 pm -
1 stop7h 43m
Deal found 8/10![Multiple Airlines logo]()
$221
Find flight deals from Sioux Falls to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $231 (Frontier) |
One-way from | $111 (Frontier) |
Popular in | February |
Cheapest in | April |
Average price | $442 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 15, 2026.
Use the filters below to find and compare flights from Sioux Falls to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Mon 9/21
8:52 pm-12:14 am
1 stop5h 22m
San Francisco
Fri 9/25
11:42 am-8:07 pm
1 stop6h 25m
$240
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Fri 10/23
8:05 am-2:01 pm
1 stop7h 56m
San Francisco
Wed 10/28
4:00 pm-11:58 pm
1 stop5h 58m
$330
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Fri 9/4
6:50 pm-10:55 pm
1 stop6h 05m
San Francisco
Sun 9/6
1:54 pm-11:22 pm
1 stop7h 28m
$339
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Sat 12/5
6:00 am-11:25 am
1 stop7h 25m
San Francisco
Tue 12/8
2:25 pm-10:56 pm
1 stop6h 31m
$411
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Wed 10/21
12:52 pm-7:39 pm
2 stops8h 47m
San Francisco
Mon 10/26
5:30 am-5:23 pm
1 stop9h 53m
$411
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Fri 9/4
6:50 pm-10:55 pm
1 stop6h 05m
San Francisco
Sat 9/5
11:30 pm-10:29 am
1 stop8h 59m
$429
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Wed 10/21
5:00 pm-11:56 pm
2 stops8h 56m
San Francisco
Mon 10/26
8:59 pm-10:00 am
2 stops11h 01m
$534
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Thu 10/22
5:00 pm-11:56 pm
2 stops8h 56m
San Francisco
Mon 10/26
8:59 pm-10:00 am
2 stops11h 01m
$563
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Fri 10/23
5:00 pm-11:56 pm
2 stops8h 56m
San Francisco
Wed 10/28
10:35 am-11:22 pm
2 stops10h 47m
$569
Sioux FallsSan Francisco
FSD Sioux Falls Joe Foss Field - SFO San Francisco
FSDSFO
Sioux Falls Joe Foss Field
Mon 9/21
6:41 pm-12:30 am
1 stop7h 49m
San Francisco
Fri 9/25
7:10 pm-4:23 pm
2 stops19h 13m
$583
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to San Francisco in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Sioux Falls with our price prediction graph.
FSD-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to San Francisco
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated August 15, 2026.
Read through reviews of airlines operating flights from Sioux Falls to San Francisco, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
San Bruno
Fairfield
Emeryville
Roseville
Burlingame
Rancho Cordova
Vallejo
Cupertino
Newark
Hayward
San Ramon
Redwood City
San Carlos
Manteca
Turlock
San Lorenzo
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Sioux Falls and San Francisco flights
Browse other Sioux Falls and San Francisco flight options. Last updated on August 15, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on August 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 15, 2026.
Top 3 airlines flying from Sioux Falls to San Francisco
Discover the top 3 airlines that operate flights from Sioux Falls to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$374 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$439 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$408 | FlexibilityNo cancel fee | On-time71% |