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$258+ Cheap flights from Santo Domingo (SDQ) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — SFO
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to San Francisco are usually found in September or December, booked 64 days in advance, depart on a Thursday or Wednesday and return on a Tuesday

Cheap flight deals from Santo Domingo to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$518
(Booking.com)

One-way from

$258
(Booking.com)

Popular in

June

Cheapest in

September

Average price

$1,001
From Santo Domingo Las Americas to San Francisco
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One-way flight from Santo Domingo Las Americas to San Francisco
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Highest demand for flights based on searches. 12% potential increase in price ($94 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Santo Domingo to San Francisco

Cheapest flights from Santo Domingo to San Francisco
Explore the most affordable flight options available from Santo Domingo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1011:50 amSDQ - SFO
1 stop25h 35mFrontier
Mon 7/1410:29 pmSFO - SDQ
1 stop22h 59mFrontier
Deal found 6/11$518
This JetBlue deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/22:35 amSDQ - SFO
1 stop12h 34mJetBlue
Tue 11/116:00 amSFO - SDQ
1 stop16h 32mJetBlue
Deal found 6/11$537
This Avianca deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1611:45 amSDQ - SFO
2 stops15h 10mAvianca
Fri 8/222:20 pmSFO - SDQ
2 stops17h 30mAvianca
Deal found 6/12$552
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/262:47 pmSDQ - SFO
1 stop11h 02mDelta
Tue 9/24:10 pmSFO - SDQ
2 stops18h 12mDelta
Deal found 6/11$648
This Trip.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/911:01 amSDQ - SFO
1 stop13h 43mAeromexico
Tue 7/152:51 pmSFO - SDQ
1 stop12h 53mAeromexico
Deal found 6/11$658
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1010:55 amSDQ - SFO
2 stops26h 30mMultiple Airlines
Mon 7/1410:19 pmSFO - SDQ
1 stop15h 11mMultiple Airlines
Deal found 6/11$668
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/297:00 amSDQ - SFO
2 stops11h 56mAmerican Airlines
Thu 8/712:45 amSFO - SDQ
2 stops14h 35mAmerican Airlines
Deal found 6/10$695
This Copa Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/92:07 pmSDQ - SFO
1 stop12h 33mCopa Airlines
Mon 7/141:25 amSFO - SDQ
1 stop11h 52mCopa Airlines
Deal found 6/11$746
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/206:00 amSDQ - SFO
1 stop13h 25mUnited Airlines
Sat 6/2810:45 pmSFO - SDQ
1 stop12h 25mUnited Airlines
Deal found 6/11$966

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Santo Domingo to San Francisco that are best for you.

Fly from

Santo Domingo

Fly to

San Francisco

Route

Depart

Return

Price

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Thu 7/10

11:50 am-10:25 am

1 stop25h 35m

San Francisco

Mon 7/14

10:29 pm-12:28 am

1 stop22h 59m

$518

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Sun 11/2

2:35 am-11:09 am

1 stop12h 34m

San Francisco

Tue 11/11

6:00 am-2:32 am

1 stop16h 32m

$537

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Sat 8/16

11:45 am-11:55 pm

2 stops15h 10m

San Francisco

Fri 8/22

2:20 pm-10:50 am

2 stops17h 30m

$552

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Tue 8/26

2:47 pm-10:49 pm

1 stop11h 02m

San Francisco

Tue 9/2

4:10 pm-1:22 pm

2 stops18h 12m

$648

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Wed 7/9

11:01 am-9:44 pm

1 stop13h 43m

San Francisco

Tue 7/15

2:51 pm-6:44 am

1 stop12h 53m

$658

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Thu 7/10

10:55 am-10:25 am

2 stops26h 30m

San Francisco

Mon 7/14

10:19 pm-4:30 pm

1 stop15h 11m

$668

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Tue 7/29

7:00 am-8:26 pm

2 stops16h 26m

San Francisco

Fri 8/8

8:00 am-8:30 pm

1 stop9h 30m

$695

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Wed 7/9

2:07 pm-11:40 pm

1 stop12h 33m

San Francisco

Mon 7/14

1:25 am-4:17 pm

1 stop11h 52m

$746

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Tue 6/24

1:49 am-9:26 pm

1 stop22h 37m

$258

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Thu 7/24

11:45 am-11:55 pm

2 stops15h 10m

$280

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 13 results
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Best time to book a flight from Santo Domingo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to San Francisco

How far ahead should I book a flight from Santo Domingo to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to San Francisco. Price data was last updated on June 9, 2025.

Booking 63 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santo Domingo to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santo Domingo to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to San Francisco (average of $276). Flying from Santo Domingo to San Francisco in June is currently the most expensive (average of $364). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to SFO?

Find hourly flight availability from Santo Domingo to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

It’s typically best to fly out from Santo Domingo to San Francisco in the evening. Doing so could potentially save you 67% on the flight price compared to flying at noon, which is usually more expensive.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 12, 2025.
To help decide which airline to fly from Santo Domingo to San Francisco, see what other customers have to say about Delta, Copa Airlines and Aeromexico. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Aeromexico
7.5
Good
1,706 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
JetBlue
7.3
Good
2,925 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santo Domingo to San Francisco round-trip?

    Our cheapest airline available from Santo Domingo to San Francisco is Frontier. Our recent data shows that you can find tickets from as low as $518 on this airline. Additional options worth looking into are JetBlue and Avianca, starting at $539 and $552 round-trip. Frontier is currently priced 23% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Santo Domingo to San Francisco one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $258. Users have also found prices from $280 and $361 on Avianca and Aeromexico, respectively.

  • Can I find deals for flights from Santo Domingo to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to San Francisco.

  • Can I find deals for business class flights from Santo Domingo to San Francisco?

    Yes. Cheapflights offers flight deals from Santo Domingo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to San Francisco (average of $276). Flying from Santo Domingo to San Francisco in June is currently the most expensive (average of $364). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Roseville
Mountain View
South San Francisco
Livermore
Turlock
Santa Cruz
Manteca
Fairfield
Watsonville
Antioch
Hollister
Milpitas
Newark
Hayward
Alameda
Sunnyvale
Daly City
Union City
Campbell
Capitola

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Alternative routes for Santo Domingo to San Francisco

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Top 3 airlines flying from Santo Domingo to San Francisco

Discover the top 3 airlines that operate flights from Santo Domingo to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$430Average$642FlexibilityNo cancel feeOn-time62%
DeltaCheapest$584Average$678FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$686Average$931FlexibilityNo cancel feeOn-time71%

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