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$440+ Cheap flights from Santa Cruz de la Sierra (VVI) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SFO
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Santa Cruz de la Sierra to San Francisco

Cheapest flights from Santa Cruz de la Sierra to San Francisco
Explore the most affordable flight options available from Santa Cruz de la Sierra to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1811:40 amVVI - SFO
2 stops26h 15mUnited Airlines
Mon 12/111:20 amSFO - VVI
2 stops31h 26mUnited Airlines
Deal found 10/27$811
This United deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:40 amVVI - SFO
2 stops24h 41mMultiple Airlines
Tue 12/3012:30 amSFO - VVI
2 stops23h 06mMultiple Airlines
Deal found 10/27$829
This Cheapflightsfares deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/173:40 amVVI - SFO
2 stops22h 10mAvianca
Mon 12/111:10 pmSFO - VVI
2 stops23h 25mAvianca
Deal found 10/26$853
This Copa Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:40 amVVI - SFO
1 stop15h 37mCopa Airlines
Tue 1/612:42 amSFO - VVI
1 stop23h 02mCopa Airlines
Deal found 10/26$1,039
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/173:40 amVVI - SFO
2 stops23h 40mAvianca
Wed 1/711:10 pmSFO - VVI
2 stops23h 25mAvianca
Deal found 10/27$1,049
This Copa Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1811:40 amVVI - SFO
1 stop15h 37mCopa Airlines
Sun 11/3012:36 amSFO - VVI
1 stop23h 00mCopa Airlines
Deal found 10/27$1,051

Cheap flight deals from Santa Cruz de la Sierra to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$811
(United Airlines)

One-way from

$440
(Cheapflightsfares)

Popular in

March

Cheapest in

September

Average price

$768
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-San Francisco flights.
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From Santa Cruz de la Sierra Viru Viru Intl to San Francisco
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One-way flight from Santa Cruz de la Sierra Viru Viru Intl to San Francisco
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Highest demand for flights based on searches. 15% potential increase in price ($152 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to San Francisco that are best for you.

Fly from

Santa Cruz de la Sierra

Fly to

San Francisco

Route

Depart

Return

Price

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/18

11:40 am-9:45 am

2 stops26h 05m

San Francisco

Mon 12/1

9:20 pm-10:46 pm

2 stops21h 26m

$811

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Sat 12/20

3:40 am-12:21 am

2 stops24h 41m

San Francisco

Tue 12/30

12:30 am-3:36 am

2 stops23h 06m

$829

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/18

11:40 am-11:17 pm

1 stop15h 37m

San Francisco

Tue 1/6

12:42 am-3:44 am

1 stop23h 02m

$1,039

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/17

3:40 am-11:20 pm

2 stops23h 40m

San Francisco

Tue 1/6

1:35 am-2:35 am

2 stops21h 00m

$1,049

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/18

11:40 am-11:17 pm

1 stop15h 37m

San Francisco

Sun 11/30

12:36 am-3:36 am

1 stop23h 00m

$1,051

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Sun 11/2

3:40 am-9:50 pm

2 stops22h 10m

$440

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/3

11:40 am-11:17 pm

1 stop15h 37m

$455

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/3

11:40 am-9:47 am

2 stops50h 07m

$461

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 1/13

11:44 am-9:39 pm

2 stops37h 55m

$466

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 1/15

11:44 am-8:00 am

2 stops48h 16m

$472

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 12 results
1
2

Compare providers for flights from Santa Cruz de la Sierra to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Cruz de la Sierra to San Francisco in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Cruz de la Sierra-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to San Francisco

What is the cheapest month to book a flight from Santa Cruz de la Sierra to San Francisco?

Currently, May is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to San Francisco (average of $323). Flying from Santa Cruz de la Sierra to San Francisco in March is currently the most expensive (average of $956). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated October 28, 2025.
Read reviews from past customers who have flown Copa Airlines, United Airlines, and Avianca from Santa Cruz de la Sierra to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,560 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,560 reviews
Copa Airlines
7.6
Good
1,560 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
United Airlines
7.4
Good
8,996 reviews
Copa Airlines
7.6
Good
1,560 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.6
Okay
2,468 reviews
Copa Airlines
7.6
Good
1,560 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to San Francisco?

    United Airlines can get you from Santa Cruz de la Sierra to San Francisco in just under 26h 05m. Your travel time can differ by up to . Airlines will cover a distance of 5414 mi.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to San Francisco round-trip?

    According to our current data, United Airlines ($324), Copa Airlines ($413), and Avianca ($706) offers the cheapest pricing from Santa Cruz de la Sierra to San Francisco. United Airlines is 62% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Santa Cruz de la Sierra to San Francisco one-way?

    One-way options have recently been found by users for as low as $440 on Avianca. Other airlines that offer cheap prices include Copa Airlines from $455 and United Airlines from $461 one-way.

  • Can I find deals for flights from Santa Cruz de la Sierra to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to San Francisco.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to San Francisco?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to San Francisco?

    Currently, May is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to San Francisco (average of $323). Flying from Santa Cruz de la Sierra to San Francisco in March is currently the most expensive (average of $956). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Watsonville
Sunnyvale
Santa Clara
Antioch
Manteca
Vallejo
Hollister
Vacaville
San Bruno
Foster City
Redwood City
Union City
Fairfield
Burlingame
Lodi

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Top 3 airlines flying from Santa Cruz de la Sierra to San Francisco

Discover the top 3 airlines that operate flights from Santa Cruz de la Sierra to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$324Average$854FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$413Average$1,096FlexibilityNo cancel feeOn-time70%
AviancaCheapest$706Average$1,067FlexibilityNo cancel feeOn-time71%

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