San Francisco

$485+ Cheap flights from Santa Cruz de la Sierra (VVI) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SFO
Apr 14 — Apr 211
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Cheap flight deals from Santa Cruz de la Sierra to San Francisco

Cheapest flights from Santa Cruz de la Sierra to San Francisco
Explore the most affordable flight options available from Santa Cruz de la Sierra to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.

This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:47 am
VVI
-
SFO
2 stops24h 25m
United Airlines
Tue 8/1111:30 pm
SFO
-
VVI
2 stops20h 10m
United Airlines
Deal found 3/10$975
This KAYAK deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:48 am
VVI
-
SFO
2 stops25h 37m
Copa Airlines
Thu 5/2811:59 pm
SFO
-
VVI
2 stops24h 32m
Copa Airlines
Deal found 3/13$978
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:44 am
VVI
-
SFO
2 stops23h 36m
United Airlines
Fri 11/2712:45 am
SFO
-
VVI
2 stops18h 05m
United Airlines
Deal found 3/12$984
This KAYAK deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:48 am
VVI
-
SFO
2 stops34h 10m
Copa Airlines
Tue 8/1112:45 am
SFO
-
VVI
2 stops42h 55m
Copa Airlines
Deal found 3/10$992
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:47 am
VVI
-
SFO
2 stops22h 48m
United Airlines
Fri 8/1411:59 pm
SFO
-
VVI
2 stops19h 41m
United Airlines
Deal found 3/10$993
This BusinessClass deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:48 am
VVI
-
SFO
2 stops32h 25m
Copa Airlines
Sun 7/1912:45 am
SFO
-
VVI
2 stops23h 50m
Copa Airlines
Deal found 3/14$1,017
This KAYAK deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:48 am
VVI
-
SFO
2 stops24h 28m
Copa Airlines
Thu 11/2611:05 pm
SFO
-
VVI
2 stops24h 39m
Copa Airlines
Deal found 3/12$1,023
This Gotogate deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/303:35 am
VVI
-
SFO
2 stops22h 00m
Multiple Airlines
Wed 8/121:12 am
SFO
-
VVI
1 stop18h 28m
Multiple Airlines
Deal found 3/10$1,029
This Gotogate deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:47 am
VVI
-
SFO
1 stop33h 27m
Copa Airlines
Wed 8/121:12 am
SFO
-
VVI
1 stop18h 28m
Copa Airlines
Deal found 3/10$1,043
This Flightnetwork deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:35 am
VVI
-
SFO
2 stops22h 00m
Multiple Airlines
Wed 8/121:12 am
SFO
-
VVI
1 stop18h 28m
Multiple Airlines
Deal found 3/10$1,044
This Flightnetwork deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:47 am
VVI
-
SFO
1 stop14h 53m
Copa Airlines
Tue 8/118:21 pm
SFO
-
VVI
1 stop28h 14m
Copa Airlines
Deal found 3/10$1,045

Find flight deals from Santa Cruz de la Sierra to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$975
(United Airlines)

One-way from

$485
(Kiwi.com)

Popular in

January

Cheapest in

May

Average price

$1,092
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-San Francisco flight deals.
Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-San Francisco flights.
From Santa Cruz de la Sierra Viru Viru Intl to San Francisco
One-way flight from Santa Cruz de la Sierra Viru Viru Intl to San Francisco
Highest demand for flights based on searches. 10% potential increase in price ($108 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 6/1

11:47 am-10:50 am

2 stops26h 03m

San Francisco

Thu 8/13

9:30 pm-10:40 pm

2 stops22h 10m

$975

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 6/2

11:47 am-7:35 am

2 stops22h 48m

San Francisco

Wed 8/12

12:45 am-10:40 pm

2 stops18h 55m

$975

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Sat 6/6

11:47 am-7:35 am

2 stops22h 48m

San Francisco

Tue 8/11

10:35 pm-10:40 pm

2 stops21h 05m

$993
Quickest round-trip

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/20

11:48 am-11:40 pm

1 stop14h 52m

San Francisco

Wed 5/27

1:12 am-10:38 pm

1 stop18h 26m

$1,001

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/9

11:48 am-9:16 am

2 stops24h 28m

San Francisco

Thu 11/26

11:05 pm-3:44 am

2 stops24h 39m

$1,023

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 5/7

1:12 am-11:40 pm

1 stop25h 28m

San Francisco

Tue 5/26

1:12 am-10:38 pm

1 stop18h 26m

$1,050

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/2

11:48 am-11:40 pm

1 stop14h 52m

San Francisco

Tue 8/11

1:12 am-10:40 pm

1 stop18h 28m

$1,053

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/24

3:40 am-10:25 am

3 stops33h 45m

San Francisco

Tue 4/21

2:15 pm-2:30 am

2 stops33h 15m

$1,119

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/9

3:35 am-10:15 am

3 stops33h 40m

San Francisco

Sat 4/18

2:30 am-4:45 am

3 stops23h 15m

$1,127

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/8

3:35 am-12:50 pm

2 stops36h 15m

San Francisco

Thu 9/10

11:55 pm-2:30 am

2 stops23h 35m

$1,295

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/10

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3
  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to San Francisco

What is the cheapest month to book a flight from Santa Cruz de la Sierra to San Francisco?

Currently, May is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to San Francisco (average of $321). Flying from Santa Cruz de la Sierra to San Francisco in February is currently the most expensive (average of $1,068). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated March 15, 2026.
Read reviews from past customers who have flown Copa Airlines,United Airlines, andAvianca from Santa Cruz de la Sierra to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.8

Boarding

7.8

Overall

7.5

Crew

8.1

Comfort

7.4

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Entertainment

6.8

Boarding

7.8

Overall

7.5

Crew

8.1

Comfort

7.4

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Entertainment

6.8

Boarding

7.8

Overall

7.5

Crew

8.1

Comfort

7.4

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Entertainment

6.8

Boarding

7.8

Overall

7.5

Crew

8.1

Comfort

7.4

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Santa Cruz de la Sierra to San Francisco?

    United Airlines and Copa Airlines can get you from Santa Cruz de la Sierra to San Francisco in just under 14h 52m. Your travel time can differ by up to 11h 11m. Airlines will cover a distance of 5414 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to San Francisco round-trip?

    According to our current data, United Airlines ($299), Avianca ($322), and Copa Airlines ($401) offers the cheapest pricing from Santa Cruz de la Sierra to San Francisco. United Airlines is 66% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santa Cruz de la Sierra to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to San Francisco.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to San Francisco?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to San Francisco?

    Currently, May is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to San Francisco (average of $321). Flying from Santa Cruz de la Sierra to San Francisco in February is currently the most expensive (average of $1,068). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
Livermore
Roseville
Watsonville
Rancho Cordova
San Bruno
San Ramon
Sunnyvale
Vacaville
San Carlos
Redwood City
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Rohnert Park

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santa Cruz de la Sierra to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Santa Cruz de la Sierra to San Francisco

Discover the top 3 airlines that operate flights from Santa Cruz de la Sierra to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$299Average$837FlexibilityNo cancel feeOn-time69%
AviancaCheapest$322Average$1,003FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$401Average$959FlexibilityNo cancel feeOn-time70%

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