$485+ Cheap flights from Santa Cruz de la Sierra (VVI) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SFO
Apr 14 — Apr 211
Round-trip
1 adult, Economy
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Cheapest flights from Santa Cruz de la Sierra to San FranciscoExplore the most affordable flight options available from Santa Cruz de la Sierra to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
Explore the most affordable flight options available from Santa Cruz de la Sierra to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:47 am
VVI
- SFO
2 stops24h 25m
United Airlines
Tue 8/1111:30 pm
SFO
- VVI
2 stops20h 10m
United Airlines
Deal found 3/10![United Airlines logo]()
$975
This KAYAK deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:48 am
VVI
- SFO
2 stops25h 37m
Copa Airlines
Thu 5/2811:59 pm
SFO
- VVI
2 stops24h 32m
Copa Airlines
Deal found 3/13![Copa Airlines logo]()
$978
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:44 am
VVI
- SFO
2 stops23h 36m
United Airlines
Fri 11/2712:45 am
SFO
- VVI
2 stops18h 05m
United Airlines
Deal found 3/12![United Airlines logo]()
$984
This KAYAK deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:48 am
VVI
- SFO
2 stops34h 10m
Copa Airlines
Tue 8/1112:45 am
SFO
- VVI
2 stops42h 55m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$992
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:47 am
VVI
- SFO
2 stops22h 48m
United Airlines
Fri 8/1411:59 pm
SFO
- VVI
2 stops19h 41m
United Airlines
Deal found 3/10![United Airlines logo]()
$993
This BusinessClass deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:48 am
VVI
- SFO
2 stops32h 25m
Copa Airlines
Sun 7/1912:45 am
SFO
- VVI
2 stops23h 50m
Copa Airlines
Deal found 3/14![Copa Airlines logo]()
$1,017
This KAYAK deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:48 am
VVI
- SFO
2 stops24h 28m
Copa Airlines
Thu 11/2611:05 pm
SFO
- VVI
2 stops24h 39m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$1,023
This Gotogate deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/303:35 am
VVI
- SFO
2 stops22h 00m
Multiple Airlines
Wed 8/121:12 am
SFO
- VVI
1 stop18h 28m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$1,029
This Gotogate deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:47 am
VVI
- SFO
1 stop33h 27m
Copa Airlines
Wed 8/121:12 am
SFO
- VVI
1 stop18h 28m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$1,043
This Flightnetwork deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:35 am
VVI
- SFO
2 stops22h 00m
Multiple Airlines
Wed 8/121:12 am
SFO
- VVI
1 stop18h 28m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$1,044
This Flightnetwork deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:47 am
VVI
- SFO
1 stop14h 53m
Copa Airlines
Tue 8/118:21 pm
SFO
- VVI
1 stop28h 14m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$1,045
Best flights from Santa Cruz de la Sierra to San FranciscoDiscover carefully curated flight deals from Santa Cruz de la Sierra to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
Discover carefully curated flight deals from Santa Cruz de la Sierra to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:47 am
VVI
- SFO
2 stops26h 03m
United Airlines
Thu 8/139:30 pm
SFO
- VVI
2 stops22h 10m
United Airlines
Deal found 3/10![United Airlines logo]()
$975
This Copa Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:48 am
VVI
- SFO
1 stop14h 52m
Copa Airlines
Wed 5/271:12 am
SFO
- VVI
1 stop18h 26m
Copa Airlines
Deal found 3/13![Copa Airlines logo]()
$1,001
This Mytrip deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:40 am
VVI
- SFO
3 stops33h 45m
Multiple Airlines
Tue 4/212:15 pm
SFO
- VVI
2 stops33h 15m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$1,119
This Avianca deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:35 am
VVI
- SFO
2 stops36h 15m
Avianca
Thu 9/1011:55 pm
SFO
- VVI
2 stops23h 35m
Avianca
Deal found 3/10![Avianca logo]()
$1,295
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:47 am
VVI
- SFO
2 stops22h 48m
United Airlines
Wed 8/1212:45 am
SFO
- VVI
2 stops18h 55m
United Airlines
Deal found 3/10![United Airlines logo]()
$975
This KAYAK deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:48 am
VVI
- SFO
2 stops24h 28m
Copa Airlines
Thu 11/2611:05 pm
SFO
- VVI
2 stops24h 39m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$1,023
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:47 am
VVI
- SFO
2 stops22h 48m
United Airlines
Tue 8/1110:35 pm
SFO
- VVI
2 stops21h 05m
United Airlines
Deal found 3/10![United Airlines logo]()
$993
This Mytrip deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:35 am
VVI
- SFO
3 stops33h 40m
Multiple Airlines
Sat 4/182:30 am
SFO
- VVI
3 stops23h 15m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$1,127
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:12 am
VVI
- SFO
1 stop25h 28m
Copa Airlines
Tue 5/261:12 am
SFO
- VVI
1 stop18h 26m
Copa Airlines
Deal found 3/13![Copa Airlines logo]()
$1,050
This Copa Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:48 am
VVI
- SFO
1 stop14h 52m
Copa Airlines
Tue 8/111:12 am
SFO
- VVI
1 stop18h 28m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$1,053
Last-minute flights from Santa Cruz de la Sierra to San FranciscoDiscover last-minute flight deals from Santa Cruz de la Sierra to San Francisco. Data last updated March 15, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Cruz de la Sierra to San Francisco. Data last updated March 15, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:40 am
VVI
- SFO
2 stops20h 20m
Multiple Airlines
Tue 4/2111:55 pm
SFO
- VVI
2 stops23h 35m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$1,119
This Mytrip deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/13:35 am
VVI
- SFO
3 stops33h 50m
Multiple Airlines
Wed 8/1211:55 pm
SFO
- VVI
2 stops23h 35m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$1,138
This KAYAK deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:48 am
VVI
- SFO
2 stops34h 10m
Copa Airlines
Tue 8/1112:45 am
SFO
- VVI
2 stops42h 55m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$992
This KAYAK deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:48 am
VVI
- SFO
2 stops24h 28m
Copa Airlines
Thu 11/2611:05 pm
SFO
- VVI
2 stops24h 39m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$1,023
This Mytrip deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:35 am
VVI
- SFO
3 stops33h 40m
Multiple Airlines
Sat 4/182:30 am
SFO
- VVI
3 stops23h 15m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$1,127
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/193:35 am
VVI
- SFO
2 stops36h 15m
Avianca
Thu 5/282:15 pm
SFO
- VVI
3 stops33h 15m
Avianca
Deal found 3/13![Avianca logo]()
$1,202
This Booking.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/193:35 am
VVI
- SFO
2 stops22h 00m
Avianca
Mon 7/207:45 am
SFO
- VVI
3 stops39h 45m
Avianca
Deal found 3/14![Avianca logo]()
$1,256
This KAYAK deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:48 am
VVI
- SFO
2 stops25h 37m
Copa Airlines
Thu 5/2811:59 pm
SFO
- VVI
2 stops24h 32m
Copa Airlines
Deal found 3/13![Copa Airlines logo]()
$978
This BusinessClass deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:48 am
VVI
- SFO
2 stops32h 25m
Copa Airlines
Sun 7/1912:45 am
SFO
- VVI
2 stops23h 50m
Copa Airlines
Deal found 3/14![Copa Airlines logo]()
$1,017
One-way flights from Santa Cruz de la Sierra to San FranciscoSearch for one-way flight options from Santa Cruz de la Sierra to San Francisco. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
Search for one-way flight options from Santa Cruz de la Sierra to San Francisco. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:35 am
VVI
- SFO
3 stops22h 29m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$485
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:35 am
VVI
- SFO
2 stops22h 29m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$492
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:35 am
VVI
- SFO
3 stops41h 50m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$507
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:35 am
VVI
- SFO
3 stops22h 29m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$511
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:35 am
VVI
- SFO
3 stops41h 50m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:35 am
VVI
- SFO
3 stops21h 56m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$515
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/303:35 am
VVI
- SFO
3 stops41h 50m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$520
This Trip.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/183:35 am
VVI
- SFO
2 stops21h 56m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$551
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:35 am
VVI
- SFO
3 stops22h 29m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$553
This Copa Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:48 am
VVI
- SFO
1 stop14h 52m
Copa Airlines
Deal found 3/13![Copa Airlines logo]()
$558
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:35 am
VVI
- SFO
3 stops20h 38m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$560
Find flight deals from Santa Cruz de la Sierra to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $975 (United Airlines) |
One-way from | $485 (Kiwi.com) |
Popular in | January |
Cheapest in | May |
Average price | $1,092 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Cruz de la Sierra to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa Cruz de la SierraSan Francisco
VVI - SFO
VVISFO
Santa Cruz de la Sierra Viru Viru Intl
Mon 6/1
11:47 am-10:50 am
2 stops26h 03m
San Francisco
Thu 8/13
9:30 pm-10:40 pm
2 stops22h 10m
$975
Santa Cruz de la SierraSan Francisco
VVI - SFO
VVISFO
Santa Cruz de la Sierra Viru Viru Intl
Tue 6/2
11:47 am-7:35 am
2 stops22h 48m
San Francisco
Wed 8/12
12:45 am-10:40 pm
2 stops18h 55m
$975
Santa Cruz de la SierraSan Francisco
VVI - SFO
VVISFO
Santa Cruz de la Sierra Viru Viru Intl
Sat 6/6
11:47 am-7:35 am
2 stops22h 48m
San Francisco
Tue 8/11
10:35 pm-10:40 pm
2 stops21h 05m
$993
Quickest round-trip
Santa Cruz de la SierraSan Francisco
VVI - SFO
VVISFO
Santa Cruz de la Sierra Viru Viru Intl
Mon 4/20
11:48 am-11:40 pm
1 stop14h 52m
San Francisco
Wed 5/27
1:12 am-10:38 pm
1 stop18h 26m
$1,001
Santa Cruz de la SierraSan Francisco
VVI - SFO
VVISFO
Santa Cruz de la Sierra Viru Viru Intl
Thu 4/9
11:48 am-9:16 am
2 stops24h 28m
San Francisco
Thu 11/26
11:05 pm-3:44 am
2 stops24h 39m
$1,023
Santa Cruz de la SierraSan Francisco
VVI - SFO
VVISFO
Santa Cruz de la Sierra Viru Viru Intl
Thu 5/7
1:12 am-11:40 pm
1 stop25h 28m
San Francisco
Tue 5/26
1:12 am-10:38 pm
1 stop18h 26m
$1,050
Santa Cruz de la SierraSan Francisco
VVI - SFO
VVISFO
Santa Cruz de la Sierra Viru Viru Intl
Thu 4/2
11:48 am-11:40 pm
1 stop14h 52m
San Francisco
Tue 8/11
1:12 am-10:40 pm
1 stop18h 28m
$1,053
Santa Cruz de la SierraSan Francisco
VVI - SFO
VVISFO
Santa Cruz de la Sierra Viru Viru Intl
Tue 3/24
3:40 am-10:25 am
3 stops33h 45m
San Francisco
Tue 4/21
2:15 pm-2:30 am
2 stops33h 15m
$1,119
Santa Cruz de la SierraSan Francisco
VVI - SFO
VVISFO
Santa Cruz de la Sierra Viru Viru Intl
Thu 4/9
3:35 am-10:15 am
3 stops33h 40m
San Francisco
Sat 4/18
2:30 am-4:45 am
3 stops23h 15m
$1,127
Santa Cruz de la SierraSan Francisco
VVI - SFO
VVISFO
Santa Cruz de la Sierra Viru Viru Intl
Tue 9/8
3:35 am-12:50 pm
2 stops36h 15m
San Francisco
Thu 9/10
11:55 pm-2:30 am
2 stops23h 35m
$1,295
Showing 1-10 of 21 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Cruz de la Sierra to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santa Cruz de la Sierra with our price prediction graph.
VVI-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Cruz de la Sierra to San Francisco
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated March 15, 2026.
Read reviews from past customers who have flown Copa Airlines,United Airlines, andAvianca from Santa Cruz de la Sierra to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Boarding
7.8
Overall
7.5
Crew
8.1
Comfort
7.4
Food
6.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Boarding
7.8
Overall
7.5
Crew
8.1
Comfort
7.4
Food
6.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Boarding
7.8
Overall
7.5
Crew
8.1
Comfort
7.4
Food
6.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Boarding
7.8
Overall
7.5
Crew
8.1
Comfort
7.4
Food
6.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Santa Cruz de la Sierra to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
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Santa Cruz de la Sierra and San Francisco flights
Browse other Santa Cruz de la Sierra and San Francisco flight options. Last updated on March 15, 2026.
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Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 15, 2026.
Top 3 airlines flying from Santa Cruz de la Sierra to San Francisco
Discover the top 3 airlines that operate flights from Santa Cruz de la Sierra to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$837 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$322 | Average$1,003 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$401 | Average$959 | FlexibilityNo cancel fee | On-time70% |