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$420+ Cheap flights from Rome (ROM) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — SFO
Oct 19 — Oct 261
Sun 10/19
Sun 10/26
1 adult, Economy
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Cheapflights Tip: The best prices from Rome to San Francisco are usually found in March or February, booked 60 days in advance, depart on a Monday or Friday and return on a Tuesday

Cheap flight deals from Rome to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Rome (ROM) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 19, 2025.

Round-trip from

$591
(lol.travel)

One-way from

$420
(Kiwi.com)

Popular in

July

Cheapest in

March

Average price

$646

Good round-trip deal

$695 or less

Good one-way deal

$701 or less
From Rome (ROM) to San Francisco
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One-way flight from Rome (ROM) to San Francisco
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Highest demand for flights based on searches. 10% potential increase in price ($83 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Rome (ROM) to San Francisco.
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Price to beat on a one-way flight from Rome (ROM) to San Francisco.
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Find flight deals from Rome to San Francisco

Cheapest flights from Rome to San Francisco
Explore the most affordable flight options available from Rome to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2025.

This lol.travel deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/177:05 amFCO - SFO
1 stop14h 35mUnited Airlines
Sun 11/3012:30 amSFO - FCO
1 stop22h 15mUnited Airlines
Deal found 9/17$591
This lol.travel deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:10 amFCO - SFO
Nonstop12h 55mITA Airways
Thu 11/273:05 pmSFO - FCO
Nonstop12h 10mITA Airways
Deal found 9/17$593
This lol.travel deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:10 amFCO - SFO
Nonstop12h 55mITA Airways
Thu 11/203:05 pmSFO - FCO
Nonstop12h 10mITA Airways
Deal found 9/18$594
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/249:20 amFCO - SFO
Nonstop13h 05mITA Airways
Wed 10/13:15 pmSFO - FCO
Nonstop12h 00mITA Airways
Deal found 9/17$596
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/218:00 amFCO - SFO
2 stops20h 05mUnited Airlines
Fri 10/317:50 pmSFO - FCO
2 stops19h 10mUnited Airlines
Deal found 9/17$598
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/179:45 amFCO - SFO
2 stops22h 12mUnited Airlines
Fri 10/317:50 pmSFO - FCO
2 stops19h 10mUnited Airlines
Deal found 9/17$601
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/207:55 pmFCO - SFO
1 stop26h 40mTAP AIR PORTUGAL
Sat 11/15:35 pmSFO - FCO
1 stop22h 30mTAP AIR PORTUGAL
Deal found 9/17$604
This oojo deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:35 pmFCO - SFO
1 stop27h 55mTAP AIR PORTUGAL
Wed 12/34:35 pmSFO - FCO
1 stop22h 30mTAP AIR PORTUGAL
Deal found 9/18$606
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/228:00 amFCO - SFO
2 stops17h 00mMultiple Airlines
Wed 10/293:40 pmSFO - FCO
2 stops17h 30mMultiple Airlines
Deal found 9/17$607
This Iberia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:35 amFCO - SFO
2 stops23h 34mIberia
Fri 10/176:51 amSFO - FCO
1 stop15h 14mIberia
Deal found 9/17$608
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/24:25 pmCIA - SFO
2 stops28h 25mMultiple Airlines
Sun 11/91:55 pmSFO - CIA
2 stops20h 45mMultiple Airlines
Deal found 9/18$865
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:05 amCIA - SFO
2 stops18h 30mMultiple Airlines
Sat 11/85:20 pmSFO - CIA
2 stops19h 05mMultiple Airlines
Deal found 9/17$878

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Rome to San Francisco that are best for you.

Fly from

Rome

Fly to

San Francisco

Route

Depart

Return

Price

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Fri 10/17

9:45 am-10:57 pm

2 stops22h 12m

San Francisco

Fri 10/31

7:50 pm-11:00 pm

2 stops19h 10m

$601

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Tue 11/25

7:05 am-12:40 pm

1 stop14h 35m

San Francisco

Wed 12/3

6:30 am-8:30 am

2 stops17h 00m

$649

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Mon 11/24

7:05 am-3:55 pm

1 stop17h 50m

San Francisco

Tue 12/2

6:30 am-8:30 am

2 stops17h 00m

$649

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Thu 11/13

7:05 am-12:40 pm

1 stop14h 35m

San Francisco

Wed 11/19

7:00 am-7:45 am

1 stop15h 45m

$649

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Sat 11/8

9:10 am-1:05 pm

Nonstop12h 55m

San Francisco

Thu 11/13

3:05 pm-12:15 pm

Nonstop12h 10m

$650

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Wed 10/22

9:20 am-1:25 pm

Nonstop13h 05m

San Francisco

Mon 10/27

4:05 pm-12:15 pm

Nonstop12h 10m

$650

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Fri 11/14

6:10 am-11:50 am

1 stop14h 40m

San Francisco

Mon 11/24

10:30 am-3:20 pm

2 stops19h 50m

$654

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Mon 10/13

6:00 pm-1:50 pm

1 stop28h 50m

San Francisco

Tue 10/28

3:50 pm-9:55 pm

2 stops22h 05m

$656

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Tue 11/18

7:05 am-7:07 pm

2 stops21h 02m

San Francisco

Sat 2/14

7:00 am-11:05 am

2 stops19h 05m

$656

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Thu 11/6

7:40 am-8:14 pm

2 stops21h 34m

San Francisco

Tue 11/11

5:30 pm-4:55 pm

1 stop14h 25m

$659

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 39 results
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The best insider tips for Rome to San Francisco flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Rome to San Francisco trip
Airports
FCO

Consider using Fast Track at FCO for a quicker security and passport control experience, especially if you're not flying business class.

Read more about FCOby Robert Schrader
SFO

Use BART for an affordable 40-minute trip from SFO to downtown San Francisco. Purchase a Clipper Card or use the app for fare payment.

Read more about SFOby Harriet Baskas
Our travel experts
Robert Schrader

Robert Schrader

Expert on FCO

Robert Schrader

Robert Schrader

One of the web's original travel bloggers, Robert launched his first site Leave Your Daily Hell in 2009. Since then, he's expanded into destination niche sites (one each for Japan, Thailand and Taiwan), in addition to having written for the inflight magazines of Singapore Airlines and Korean Air. Overall, he's visited nearly 100 countries, and flies business as often as possible.

Read more
Harriet Baskas

Harriet Baskas

Expert on SFO

Harriet Baskas

Harriet Baskas

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more

Best time to book a flight from Rome to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to San Francisco

How far ahead should I book a flight from Rome to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Rome to San Francisco. Price data was last updated on September 12, 2025.

The best time to book flights from Rome to San Francisco is 60 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Rome to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Rome to San Francisco (average of $276). Flying from Rome to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROM to SFO?

Find hourly flight availability from Rome to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 19, 2025.

One of the essential ways to save on airfare from Rome to San Francisco is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 24% on airfare.

Weekly flight availability from Rome to San Francisco

Explore weekly flight availability from Rome to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 19, 2025.

The most flights from ROM to SFO are scheduled on a Wednesday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (4 on average).

How much does it cost to fly round-trip from Rome to San Francisco?

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 19, 2025.
See what other customers who have flown with United Airlines, Lufthansa, and ITA Airways from Rome to San Francisco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Boarding

7.7

Entertainment

7.1

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Boarding

7.7

Entertainment

7.1

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
Lufthansa
6.8
Okay
7,415 reviews
United Airlines
7.4
Good
8,926 reviews

Boarding

7.7

Entertainment

7.1

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
ITA Airways
6.7
Okay
1,037 reviews
United Airlines
7.4
Good
8,926 reviews

Boarding

7.7

Entertainment

7.1

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
British Airways
6.7
Okay
7,373 reviews
United Airlines
7.4
Good
8,926 reviews

Boarding

7.7

Entertainment

7.1

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
Condor
6.3
Okay
367 reviews
United Airlines
7.4
Good
8,926 reviews

Boarding

7.7

Entertainment

7.1

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Rome to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Rome?

    For a flight from Rome to San Francisco, you will be flying into San Francisco. San Francisco (SFO) is just 11.8 mi from the center of the city. San Francisco is the only San Francisco airport and it handles 4 inbound flights from Rome per day. 5 airlines have flights to San Francisco from Rome on a regular basis.

  • How long is the flight from Rome to San Francisco?

    For as low as $650, United Airlines can have you in San Francisco from Rome in 12h 55m. There are 6246 mi between Rome and San Francisco. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Rome to San Francisco round-trip?

    TAP AIR PORTUGAL, at $426, was found to be the cheapest airline from Rome to San Francisco.Alternate airlines to your destination round-trip include United Airlines and ITA Airways. These flights start at 38% lower than the current average price 3 months from now.

  • What are the most reliable airlines from Rome to San Francisco?

    Consider United Airlines (75%), Lufthansa (75%) or SAUDIA (57%) when booking your flight. These represent the most reliable airlines when flying from Rome to San Francisco.

  • What are the cheapest flights from Rome to San Francisco?

    The cheapest flight price from Rome to San Francisco is $562. On average you can expect to pay $2,075. The most popular route, (Rome Fiumicino - San Francisco), can usually be booked for $468.

  • Can I find deals for flights from Rome to San Francisco that include hotel bookings?

    Yes. In addition to deals on Rome to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to San Francisco.

  • Can I find deals for business class flights from Rome to San Francisco?

    Yes. Cheapflights offers flight deals from Rome to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rome to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Rome to San Francisco (average of $276). Flying from Rome to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Santa Clara
Manteca
Sunnyvale
Hollister
Vacaville
Foster City
Union City
Vallejo
Burlingame
Redwood City
San Mateo
San Leandro
Lathrop

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from Rome to San Francisco

Discover the top 5 airlines that operate flights from Rome to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
TAP AIR PORTUGALCheapest$426Average$555FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$574Average$772FlexibilityNo cancel feeOn-time69%
ITA AirwaysCheapest$575Average$733FlexibilityNo cancel feeOn-time81%
LufthansaCheapest$610Average$818FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$624Average$806FlexibilityNo cancel feeOn-time70%

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