$111+ Cheap flights from Islip, NY to San Francisco (ISP - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — SFO
May 18 — May 251
Round-trip
1 adult, Economy
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Find cheap flights from Islip to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Islip to San Francisco
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Cheapest flights from Islip to San FranciscoExplore the most affordable flight options available from Islip to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
Explore the most affordable flight options available from Islip to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
This CheapOair deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:48 am
ISP
- SFO
1 stop26h 41m
Frontier
Tue 7/218:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/15![Frontier logo]()
$355
This Travelocity deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1810:48 am
ISP
- SFO
1 stop26h 41m
Frontier
Sat 7/258:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/17![Frontier logo]()
$420
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:55 pm
ISP
- SFO
2 stops10h 30m
Southwest
Sun 6/147:10 pm
SFO
- ISP
2 stops10h 10m
Southwest
Deal found 4/13![Southwest logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:48 am
ISP
- SFO
1 stop26h 46m
Frontier
Mon 6/228:21 pm
SFO
- ISP
2 stops34h 42m
Frontier
Deal found 4/14![Frontier logo]()
$443
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:20 am
ISP
- SFO
1 stop8h 05m
Southwest
Sat 6/610:10 am
SFO
- ISP
2 stops10h 00m
Southwest
Deal found 4/15![Southwest logo]()
$448
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:30 pm
ISP
- SFO
2 stops11h 00m
Southwest
Sat 7/259:30 pm
SFO
- ISP
1 stop11h 15m
Southwest
Deal found 4/17![Southwest logo]()
$478
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:30 pm
ISP
- SFO
2 stops10h 40m
Southwest
Mon 5/1810:55 pm
SFO
- ISP
2 stops10h 00m
Southwest
Deal found 4/13![Southwest logo]()
$479
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:43 pm
ISP
- SFO
2 stops18h 45m
Frontier
Tue 6/98:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/14![Frontier logo]()
$481
This CheapOair deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1210:48 am
ISP
- SFO
1 stop26h 46m
Frontier
Mon 6/158:51 pm
SFO
- ISP
1 stop16h 05m
Frontier
Deal found 4/16![Frontier logo]()
$485
Best flights from Islip to San FranciscoDiscover carefully curated flight deals from Islip to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
Discover carefully curated flight deals from Islip to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:20 am
ISP
- SFO
1 stop8h 05m
Southwest
Sat 6/610:10 am
SFO
- ISP
2 stops10h 00m
Southwest
Deal found 4/15![Southwest logo]()
$448
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:30 pm
ISP
- SFO
2 stops11h 00m
Southwest
Sat 7/259:30 pm
SFO
- ISP
1 stop11h 15m
Southwest
Deal found 4/17![Southwest logo]()
$478
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:30 pm
ISP
- SFO
2 stops10h 40m
Southwest
Mon 5/1810:55 pm
SFO
- ISP
2 stops10h 00m
Southwest
Deal found 4/13![Southwest logo]()
$479
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1712:25 pm
ISP
- SFO
2 stops10h 30m
Southwest
Mon 6/226:10 pm
SFO
- ISP
2 stops10h 55m
Southwest
Deal found 4/14![Southwest logo]()
$487
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1812:30 pm
ISP
- SFO
1 stop8h 00m
Southwest
Mon 6/226:45 pm
SFO
- ISP
2 stops10h 20m
Southwest
Deal found 4/16![Southwest logo]()
$518
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:10 pm
ISP
- SFO
1 stop8h 15m
Southwest
Sat 5/28:20 am
SFO
- ISP
2 stops12h 00m
Southwest
Deal found 4/13![Southwest logo]()
$592
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Wed 5/69:15 pm
SFO
- ISP
1 stop11h 35m
Southwest
Deal found 4/17![Southwest logo]()
$592
Last-minute flights from Islip to San FranciscoDiscover last-minute flight deals from Islip to San Francisco. Data last updated April 18, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to San Francisco. Data last updated April 18, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:10 pm
ISP
- SFO
1 stop8h 15m
Southwest
Sat 5/28:20 am
SFO
- ISP
2 stops12h 00m
Southwest
Deal found 4/13![Southwest logo]()
$592
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:50 am
ISP
- SFO
1 stop14h 30m
Southwest
Thu 5/710:30 am
SFO
- ISP
2 stops10h 00m
Southwest
Deal found 4/17![Southwest logo]()
$598
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:07 pm
ISP
- SFO
2 stops22h 40m
Multiple Airlines
Wed 5/612:22 pm
SFO
- ISP
1 stop26h 44m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$585
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:30 pm
ISP
- SFO
2 stops10h 40m
Southwest
Mon 5/1810:55 pm
SFO
- ISP
2 stops10h 00m
Southwest
Deal found 4/13![Southwest logo]()
$479
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/254:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Thu 5/289:15 pm
SFO
- ISP
1 stop11h 35m
Southwest
Deal found 4/15![Southwest logo]()
$680
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:20 am
ISP
- SFO
1 stop8h 05m
Southwest
Sat 6/610:10 am
SFO
- ISP
2 stops10h 00m
Southwest
Deal found 4/15![Southwest logo]()
$448
One-way flights from Islip to San FranciscoSearch for one-way flight options from Islip to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
Search for one-way flight options from Islip to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
This CheapOair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Deal found 4/17![Frontier logo]()
$111
This CheapOair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Deal found 4/17![Frontier logo]()
$131
This CheapOair deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:48 am
ISP
- SFO
1 stop26h 46m
Frontier
Deal found 4/18![Frontier logo]()
$151
This Trip.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:02 pm
ISP
- SFO
2 stops52h 47m
Frontier
Deal found 4/13![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:43 pm
ISP
- SFO
2 stops18h 19m
Breeze Airways
Deal found 4/15![Breeze Airways logo]()
$204
This CheapOair deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:41 pm
ISP
- SFO
1 stop20h 48m
Frontier
Deal found 4/14![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/172:28 pm
ISP
- SFO
3 stops32h 28m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:33 pm
ISP
- SFO
3 stops29h 08m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$233
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:05 am
ISP
- SFO
1 stop8h 30m
Southwest
Deal found 4/15![Southwest logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:27 pm
ISP
- SFO
3 stops30h 37m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$238
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:10 am
ISP
- SFO
1 stop9h 50m
Southwest
Deal found 4/15![Southwest logo]()
$244
Find flight deals from Islip to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $355 (CheapOair) |
One-way from | $111 (CheapOair) |
Popular in | December |
Cheapest in | January |
Average price | $400 |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from Islip to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Sat 5/30
9:20 am-2:25 pm
1 stop8h 05m
San Francisco
Sat 6/6
10:10 am-11:10 pm
2 stops10h 00m
$448
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Sat 7/18
3:30 pm-11:30 pm
2 stops11h 00m
San Francisco
Sat 7/25
9:30 pm-11:45 am
1 stop11h 15m
$478
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Mon 5/11
4:30 pm-12:10 am
2 stops10h 40m
San Francisco
Mon 5/18
10:55 pm-11:55 am
2 stops10h 00m
$479
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Wed 6/17
12:25 pm-7:55 pm
2 stops10h 30m
San Francisco
Mon 6/22
6:10 pm-8:05 am
2 stops10h 55m
$487
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Thu 6/18
12:30 pm-5:30 pm
1 stop8h 00m
San Francisco
Mon 6/22
6:45 pm-8:05 am
2 stops10h 20m
$518
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Tue 4/28
4:10 pm-9:25 pm
1 stop8h 15m
San Francisco
Sat 5/2
8:20 am-11:20 pm
2 stops12h 00m
$592
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Mon 5/4
4:30 pm-11:20 pm
1 stop9h 50m
San Francisco
Wed 5/6
9:15 pm-11:50 am
1 stop11h 35m
$592
Cheapest one-way
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Wed 6/24
10:48 am-10:34 am
1 stop26h 46m
$131
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Wed 8/12
6:05 am-1:50 pm
2 stops10h 45m
$239
Quickest one-way
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Tue 5/26
4:10 pm-9:25 pm
1 stop8h 15m
$256
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Islip to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to San Francisco in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Islip, New York-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Islip, New York-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Islip to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Islip with our price prediction graph.
ISP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Islip to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
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