$111+ Cheap flights from Islip, NY to San Francisco (ISP - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — SFO
May 10 — May 171
Round-trip
1 adult, Economy
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Find cheap flights from Islip to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Islip to San Francisco
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Cheapest flights from Islip to San FranciscoExplore the most affordable flight options available from Islip to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from Islip to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This CheapOair deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Thu 6/118:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/5![Frontier logo]()
$235
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:02 pm
ISP
- SFO
1 stop19h 39m
Frontier
Sun 6/78:44 pm
SFO
- ISP
1 stop10h 21m
Frontier
Deal found 4/6![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Tue 6/98:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/6![Frontier logo]()
$255
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:48 am
ISP
- SFO
1 stop26h 41m
Frontier
Sun 6/218:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/6![Frontier logo]()
$270
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Tue 6/98:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/8![Frontier logo]()
$290
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:48 am
ISP
- SFO
1 stop26h 46m
Frontier
Mon 6/298:51 pm
SFO
- ISP
1 stop16h 05m
Frontier
Deal found 4/9![Frontier logo]()
$315
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:48 am
ISP
- SFO
1 stop26h 41m
Frontier
Tue 6/238:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/6![Frontier logo]()
$335
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:41 pm
ISP
- SFO
1 stop20h 48m
Frontier
Sun 9/68:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/8![Frontier logo]()
$355
This CheapOair deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Wed 6/108:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/7![Frontier logo]()
$380
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:48 am
ISP
- SFO
1 stop26h 46m
Frontier
Thu 7/28:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/9![Frontier logo]()
$384
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:10 pm
ISP
- SFO
1 stop8h 15m
Southwest
Wed 4/295:25 am
SFO
- ISP
2 stops10h 05m
Southwest
Deal found 4/7![Southwest logo]()
$388
Best flights from Islip to San FranciscoDiscover carefully curated flight deals from Islip to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from Islip to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:02 pm
ISP
- SFO
1 stop19h 39m
Frontier
Tue 6/98:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/6![Frontier logo]()
$250
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/54:10 pm
ISP
- SFO
1 stop8h 15m
Southwest
Tue 5/1211:25 pm
SFO
- ISP
2 stops9h 30m
Southwest
Deal found 4/7![Southwest logo]()
$388
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:48 am
ISP
- SFO
1 stop26h 41m
Frontier
Tue 7/288:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/6![Frontier logo]()
$270
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Tue 6/98:51 pm
SFO
- ISP
1 stop10h 12m
Frontier
Deal found 4/9![Frontier logo]()
$290
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Sat 5/29:15 pm
SFO
- ISP
1 stop11h 35m
Southwest
Deal found 4/5![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:20 am
ISP
- SFO
2 stops12h 35m
Southwest
Sat 5/306:15 am
SFO
- ISP
2 stops14h 05m
Southwest
Deal found 4/10![Southwest logo]()
$409
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:10 pm
ISP
- SFO
2 stops10h 05m
Southwest
Thu 5/1410:10 am
SFO
- ISP
2 stops10h 20m
Southwest
Deal found 4/9![Southwest logo]()
$445
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/94:41 pm
ISP
- SFO
1 stop20h 53m
Frontier
Mon 6/158:51 pm
SFO
- ISP
1 stop16h 05m
Frontier
Deal found 4/9![Frontier logo]()
$476
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:10 am
ISP
- SFO
2 stops11h 00m
Southwest
Sun 9/610:30 pm
SFO
- ISP
1 stop8h 10m
Southwest
Deal found 4/7![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:55 am
ISP
- SFO
2 stops12h 30m
Southwest
Mon 9/147:55 pm
SFO
- ISP
2 stops11h 20m
Southwest
Deal found 4/8![Southwest logo]()
$477
Last-minute flights from Islip to San FranciscoDiscover last-minute flight deals from Islip to San Francisco. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to San Francisco. Data last updated April 10, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Fri 4/2410:30 am
SFO
- ISP
2 stops10h 00m
Southwest
Deal found 4/6![Southwest logo]()
$592
This KAYAK deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:04 pm
ISP
- SFO
1 stop29h 52m
JetBlue
Fri 4/2411:05 pm
SFO
- ISP
1 stop18h 18m
JetBlue
Deal found 4/9![JetBlue logo]()
$1,198
One-way flights from Islip to San FranciscoSearch for one-way flight options from Islip to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from Islip to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:02 pm
ISP
- SFO
1 stop19h 39m
Frontier
Deal found 4/6![Frontier logo]()
$111
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Deal found 4/6![Frontier logo]()
$116
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/1410:48 am
ISP
- SFO
1 stop26h 41m
Frontier
Deal found 4/6![Frontier logo]()
$131
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Deal found 4/6![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:07 pm
ISP
- SFO
2 stops53h 38m
Frontier
Deal found 4/7![Frontier logo]()
$192
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:10 pm
ISP
- SFO
2 stops10h 25m
Southwest
Deal found 4/7![Southwest logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:31 pm
ISP
- SFO
3 stops44h 21m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$205
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1310:48 am
ISP
- SFO
1 stop26h 41m
Frontier
Deal found 4/6![Frontier logo]()
$216
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Deal found 4/6![Frontier logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:49 pm
ISP
- SFO
3 stops49h 45m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$267
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:41 pm
ISP
- SFO
1 stop20h 53m
Frontier
Deal found 4/8![Frontier logo]()
$276
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Deal found 4/7![Southwest logo]()
$294
Find flight deals from Islip to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $235 (CheapOair) |
One-way from | $111 (CheapOair) |
Popular in | December |
Cheapest in | January |
Average price | $398 |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Islip to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Tue 6/2
6:02 pm-10:41 am
1 stop19h 39m
San Francisco
Tue 6/9
8:51 pm-10:03 am
1 stop10h 12m
$250
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Sat 7/25
10:48 am-10:29 am
1 stop26h 41m
San Francisco
Tue 7/28
8:51 pm-10:03 am
1 stop10h 12m
$270
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Thu 6/4
11:00 am-10:41 am
1 stop26h 41m
San Francisco
Tue 6/9
8:51 pm-10:03 am
1 stop10h 12m
$290
Quickest round-trip
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Tue 5/5
4:10 pm-9:25 pm
1 stop8h 15m
San Francisco
Tue 5/12
11:25 pm-11:55 am
2 stops9h 30m
$388
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Thu 4/30
4:30 pm-11:20 pm
1 stop9h 50m
San Francisco
Sat 5/2
9:15 pm-11:50 am
1 stop11h 35m
$404
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Sat 5/23
9:20 am-6:55 pm
2 stops12h 35m
San Francisco
Sat 5/30
6:15 am-11:20 pm
2 stops14h 05m
$409
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Tue 5/12
4:10 pm-11:15 pm
2 stops10h 05m
San Francisco
Thu 5/14
10:10 am-11:30 pm
2 stops10h 20m
$445
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Thu 9/3
6:10 am-2:10 pm
2 stops11h 00m
San Francisco
Sun 9/6
10:30 pm-9:40 am
1 stop8h 10m
$472
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Tue 6/9
4:41 pm-10:34 am
1 stop20h 53m
San Francisco
Mon 6/15
8:51 pm-3:56 pm
1 stop16h 05m
$476
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Sat 9/12
11:55 am-9:25 pm
2 stops12h 30m
San Francisco
Mon 9/14
7:55 pm-10:15 am
2 stops11h 20m
$477
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Islip to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to San Francisco in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Islip, New York-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Islip, New York-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Islip to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Islip with our price prediction graph.
ISP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Islip to San Francisco
Related info for your journey
Find useful and relevant information for your journey from Islip to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
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