$116+ Cheap flights from Islip, NY to San Francisco (ISP - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — SFO
Apr 14 — Apr 211
Round-trip
1 adult, Economy
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Find cheap flights from Islip to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Islip to San Francisco
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Cheapest flights from Islip to San FranciscoExplore the most affordable flight options available from Islip to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
Explore the most affordable flight options available from Islip to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
This CheapOair deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:03 am
ISP
- SFO
1 stop15h 49m
Frontier
Mon 7/2011:59 pm
SFO
- ISP
1 stop30h 09m
Frontier
Deal found 3/11![Frontier logo]()
$350
This CheapOair deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:03 am
ISP
- SFO
1 stop15h 49m
Frontier
Sun 9/611:59 pm
SFO
- ISP
1 stop30h 09m
Frontier
Deal found 3/10![Frontier logo]()
$370
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Tue 4/219:15 pm
SFO
- ISP
1 stop13h 35m
Southwest
Deal found 3/9![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:55 pm
ISP
- SFO
1 stop7h 55m
Southwest
Mon 7/209:10 pm
SFO
- ISP
1 stop7h 55m
Southwest
Deal found 3/10![Southwest logo]()
$447
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Thu 4/167:25 am
SFO
- ISP
2 stops13h 05m
Southwest
Deal found 3/12![Southwest logo]()
$464
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:10 am
ISP
- SFO
1 stop9h 50m
Southwest
Sun 8/2310:30 pm
SFO
- ISP
1 stop8h 10m
Southwest
Deal found 3/14![Southwest logo]()
$467
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Fri 5/110:55 pm
SFO
- ISP
2 stops9h 40m
Southwest
Deal found 3/11![Southwest logo]()
$472
Best flights from Islip to San FranciscoDiscover carefully curated flight deals from Islip to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
Discover carefully curated flight deals from Islip to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Tue 4/219:15 pm
SFO
- ISP
1 stop13h 35m
Southwest
Deal found 3/9![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:10 am
ISP
- SFO
1 stop9h 50m
Southwest
Sun 8/2310:30 pm
SFO
- ISP
1 stop8h 10m
Southwest
Deal found 3/14![Southwest logo]()
$467
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
ISP
- SFO
2 stops12h 25m
Southwest
Thu 4/167:25 am
SFO
- ISP
2 stops13h 05m
Southwest
Deal found 3/12![Southwest logo]()
$469
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Fri 5/110:55 pm
SFO
- ISP
2 stops9h 40m
Southwest
Deal found 3/11![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:40 pm
ISP
- SFO
1 stop8h 25m
Southwest
Thu 4/167:25 am
SFO
- ISP
2 stops13h 05m
Southwest
Deal found 3/12![Southwest logo]()
$488
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:25 pm
ISP
- SFO
1 stop8h 55m
Southwest
Wed 4/159:15 pm
SFO
- ISP
1 stop11h 35m
Southwest
Deal found 3/9![Southwest logo]()
$538
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:55 pm
ISP
- SFO
1 stop8h 45m
Southwest
Mon 4/610:55 pm
SFO
- ISP
2 stops10h 00m
Southwest
Deal found 3/12![Southwest logo]()
$544
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:40 pm
ISP
- SFO
1 stop8h 25m
Southwest
Sun 3/2910:55 pm
SFO
- ISP
2 stops9h 45m
Southwest
Deal found 3/10![Southwest logo]()
$572
Last-minute flights from Islip to San FranciscoDiscover last-minute flight deals from Islip to San Francisco. Data last updated March 15, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to San Francisco. Data last updated March 15, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:40 pm
ISP
- SFO
1 stop8h 25m
Southwest
Thu 4/167:25 am
SFO
- ISP
2 stops13h 05m
Southwest
Deal found 3/12![Southwest logo]()
$488
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:55 pm
ISP
- SFO
1 stop8h 45m
Southwest
Mon 4/610:55 pm
SFO
- ISP
2 stops10h 00m
Southwest
Deal found 3/12![Southwest logo]()
$544
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:05 pm
ISP
- SFO
2 stops10h 10m
Southwest
Sat 4/119:15 pm
SFO
- ISP
1 stop11h 35m
Southwest
Deal found 3/10![Southwest logo]()
$538
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Thu 4/167:25 am
SFO
- ISP
2 stops13h 05m
Southwest
Deal found 3/12![Southwest logo]()
$464
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Tue 4/219:15 pm
SFO
- ISP
1 stop13h 35m
Southwest
Deal found 3/9![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:30 pm
ISP
- SFO
1 stop9h 50m
Southwest
Fri 5/19:15 pm
SFO
- ISP
1 stop11h 20m
Southwest
Deal found 3/11![Southwest logo]()
$472
One-way flights from Islip to San FranciscoSearch for one-way flight options from Islip to San Francisco. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
Search for one-way flight options from Islip to San Francisco. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
This CheapOair deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Deal found 3/14![Frontier logo]()
$116
This CheapOair deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:02 pm
ISP
- SFO
1 stop19h 39m
Frontier
Deal found 3/12![Frontier logo]()
$121
This CheapOair deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Deal found 3/11![Frontier logo]()
$137
This CheapOair deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/711:00 am
ISP
- SFO
1 stop26h 41m
Frontier
Deal found 3/11![Frontier logo]()
$181
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:30 pm
ISP
- SFO
2 stops10h 50m
Southwest
Deal found 3/13![Southwest logo]()
$205
This JetBlue deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/173:07 pm
ISP
- SFO
1 stop11h 47m
JetBlue
Deal found 3/10![JetBlue logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:28 pm
ISP
- SFO
2 stops32h 32m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$238
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:20 am
ISP
- SFO
1 stop9h 50m
Southwest
Deal found 3/12![Southwest logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/910:03 am
ISP
- SFO
2 stops36h 07m
Frontier
Deal found 3/12![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:27 pm
ISP
- SFO
3 stops32h 37m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$249
This JetBlue deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/53:07 pm
ISP
- SFO
1 stop11h 47m
JetBlue
Deal found 3/13![JetBlue logo]()
$268
Find flight deals from Islip to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $350 (CheapOair) |
One-way from | $116 (CheapOair) |
Popular in | December |
Cheapest in | January |
Average price | $399 |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Islip to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Fri 4/17
4:30 pm-11:20 pm
1 stop9h 50m
San Francisco
Tue 4/21
9:15 pm-1:50 pm
1 stop13h 35m
$412
Quickest round-trip
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Fri 8/21
6:10 am-1:00 pm
1 stop9h 50m
San Francisco
Sun 8/23
10:30 pm-9:40 am
1 stop8h 10m
$467
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Thu 4/9
6:00 am-3:25 pm
2 stops12h 25m
San Francisco
Thu 4/16
7:25 am-11:30 pm
2 stops13h 05m
$469
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Fri 4/24
4:30 pm-11:20 pm
1 stop9h 50m
San Francisco
Fri 5/1
10:55 pm-11:35 am
2 stops9h 40m
$472
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Tue 3/31
4:40 pm-10:05 pm
1 stop8h 25m
San Francisco
Thu 4/16
7:25 am-11:30 pm
2 stops13h 05m
$488
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Sun 4/12
5:25 pm-11:20 pm
1 stop8h 55m
San Francisco
Wed 4/15
9:15 pm-11:50 am
1 stop11h 35m
$538
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Fri 4/3
5:55 pm-11:40 pm
1 stop8h 45m
San Francisco
Mon 4/6
10:55 pm-11:55 am
2 stops10h 00m
$544
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Wed 3/25
4:40 pm-10:05 pm
1 stop8h 25m
San Francisco
Sun 3/29
10:55 pm-11:40 am
2 stops9h 45m
$572
Cheapest one-way
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Tue 6/9
2:55 pm-10:25 pm
2 stops10h 30m
$205
IslipSan Francisco
ISP - SFO
ISPSFO
Islip Long Island
Thu 4/9
4:30 pm-12:20 am
2 stops10h 50m
$205
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Islip to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to San Francisco in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Islip, New York-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Islip, New York-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Islip to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Islip with our price prediction graph.
ISP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Islip to San Francisco
Related info for your journey
Find useful and relevant information for your journey from Islip to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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