$250+ Cheap flights from Islip, NY to San Francisco (ISP - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — SFO
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Islip to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Islip to San Francisco
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Best
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Cheapest flights from Islip to San FranciscoExplore the most affordable flight options available from Islip to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Islip to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:35 am -
2 stops11h 15m
Mon 11/99:25 pm -
1 stop11h 20m
Deal found 9/16![Southwest logo]()
$451
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:43 pm -
2 stops33h 31m
Tue 10/69:00 am -
2 stops28h 58m
Deal found 9/16![Frontier logo]()
$491
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:15 am -
1 stop9h 05m
Tue 10/69:20 am -
2 stops10h 20m
Deal found 9/16![Southwest logo]()
$509
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:35 am -
1 stop11h 10m
Thu 11/129:25 pm -
1 stop11h 20m
Deal found 9/12![Southwest logo]()
$512
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:15 am -
1 stop9h 05m
Sat 10/1711:10 am -
1 stop7h 40m
Deal found 9/12![Southwest logo]()
$533
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:40 am -
1 stop7h 55m
Wed 10/1411:40 pm -
2 stops11h 50m
Deal found 9/12![Southwest logo]()
$538
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:05 am -
2 stops12h 05m
Sun 10/189:35 pm -
1 stop13h 55m
Deal found 9/16![Southwest logo]()
$544
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:43 pm -
2 stops20h 04m
Sat 10/312:36 pm -
1 stop27h 15m
Deal found 9/14![Multiple Airlines logo]()
$552
Best flights from Islip to San FranciscoDiscover carefully curated flight deals from Islip to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Islip to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:15 am -
1 stop9h 05m
Tue 10/69:20 am -
2 stops10h 20m
Deal found 9/16![Southwest logo]()
$509
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:35 am -
1 stop11h 10m
Thu 11/129:40 am -
2 stops10h 55m
Deal found 9/12![Southwest logo]()
$512
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:35 am -
2 stops11h 15m
Mon 11/98:00 am -
2 stops12h 35m
Deal found 9/16![Southwest logo]()
$517
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:20 pm -
2 stops12h 30m
Sat 10/176:30 am -
2 stops12h 20m
Deal found 9/12![Southwest logo]()
$543
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:05 am -
2 stops12h 05m
Sun 10/189:35 pm -
1 stop13h 55m
Deal found 9/16![Southwest logo]()
$544
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
2 stops9h 30m
Mon 10/511:40 pm -
2 stops13h 05m
Deal found 9/15![Southwest logo]()
$588
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:20 pm -
2 stops12h 25m
Mon 10/1211:40 pm -
2 stops13h 05m
Deal found 9/13![Southwest logo]()
$603
Last-minute flights from Islip to San FranciscoDiscover last-minute flight deals from Islip to San Francisco. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to San Francisco. Data last updated September 17, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:43 pm -
2 stops20h 04m
Sat 10/312:36 pm -
1 stop27h 15m
Deal found 9/14![Multiple Airlines logo]()
$552
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
2 stops9h 30m
Mon 10/511:40 pm -
2 stops13h 05m
Deal found 9/15![Southwest logo]()
$588
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:43 pm -
2 stops33h 31m
Tue 10/69:00 am -
2 stops28h 58m
Deal found 9/16![Frontier logo]()
$491
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:15 am -
1 stop9h 05m
Tue 10/69:20 am -
2 stops10h 20m
Deal found 9/16![Southwest logo]()
$509
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:15 am -
1 stop9h 05m
Mon 10/1211:40 pm -
2 stops13h 05m
Deal found 9/13![Southwest logo]()
$598
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:40 am -
1 stop7h 55m
Wed 10/1411:40 pm -
2 stops11h 50m
Deal found 9/12![Southwest logo]()
$538
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:15 am -
1 stop9h 05m
Sat 10/1711:10 am -
1 stop7h 40m
Deal found 9/12![Southwest logo]()
$533
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:05 am -
2 stops12h 05m
Sun 10/189:35 pm -
1 stop13h 55m
Deal found 9/16![Southwest logo]()
$544
One-way flights from Islip to San FranciscoSearch for one-way flight options from Islip to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Islip to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:55 pm -
2 stops40h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$250
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:50 pm -
2 stops11h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$290
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:10 pm -
2 stops11h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:52 am -
2 stops37h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:15 am -
1 stop9h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$309
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:33 pm -
3 stops29h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:33 pm -
3 stops29h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$326
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
1 stop11h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:02 pm -
3 stops20h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$360
Find flight deals from Islip to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $369 (Southwest) |
One-way from | $250 (Kiwi.com) |
Popular in | June |
Cheapest in | January |
Average price | $489 |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Islip to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IslipSan Francisco
ISP Islip Long Island - SFO San Francisco
ISPSFO
Islip Long Island
Thu 10/15
3:10 pm-11:15 pm
2 stops11h 05m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$290
IslipSan Francisco
ISP Islip Long Island - SFO San Francisco
ISPSFO
Islip Long Island
Fri 10/16
3:10 pm-11:15 pm
2 stops11h 05m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$305
IslipSan Francisco
ISP Islip Long Island - SFO San Francisco
ISPSFO
Islip Long Island
Sat 10/3
6:15 am-12:20 pm
1 stop9h 05m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$309
Quickest round-trip
IslipSan Francisco
ISP Islip Long Island - SFO San Francisco
ISPSFO
Islip Long Island
Wed 10/14
9:40 am-2:35 pm
1 stop7h 55m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$336
IslipSan Francisco
ISP Islip Long Island - SFO San Francisco
ISPSFO
Islip Long Island
Thu 11/19
7:45 pm-11:09 am
3 stops18h 24m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$376
IslipSan Francisco
ISP Islip Long Island - SFO San Francisco
ISPSFO
Islip Long Island
Mon 10/12
6:00 am-9:05 am
1 stop30h 05m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$392
IslipSan Francisco
ISP Islip Long Island - SFO San Francisco
ISPSFO
Islip Long Island
Sun 10/4
7:45 pm-11:09 am
3 stops18h 24m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$426
IslipSan Francisco
ISP Islip Long Island - SFO San Francisco
ISPSFO
Islip Long Island
Thu 10/29
7:45 pm-11:09 am
3 stops18h 24m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$426
IslipSan Francisco
ISP Islip Long Island - SFO San Francisco
ISPSFO
Islip Long Island
Sun 10/25
7:45 pm-11:09 am
3 stops18h 24m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$446
IslipSan Francisco
ISP Islip Long Island - SFO San Francisco
ISPSFO
Islip Long Island
Wed 10/7
7:00 am-11:19 pm
1 stop19h 19m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$476
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Islip to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to San Francisco in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Islip, New York-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Islip, New York-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Islip to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Islip with our price prediction graph.
ISP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Islip to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
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Santa Cruz
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Burlingame
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Roseville
Fairfield
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Cupertino
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