What are the cheapest airlines to fly from Italy to San Francisco one-way?

One-way options have recently been found by users for as low as $337 on TAP AIR PORTUGAL. Other airlines that offer cheap prices include Vueling from $365 and Iberia from $436 one-way.

What are the most popular routes from Italy to San Francisco?

The most popular route from Italy to San Francisco is Rome Fiumicino - San Francisco. You may also consider Milan Malpensa - San Francisco or Milan Linate - San Francisco.

How far in advance should I book a flight from Italy to San Francisco?

To save on the cost of your flight from Italy to San Francisco, book at least 48 days before your planned departure. Booking around this time can save you about 18% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $648 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $648.

What is the cheapest month to fly from Italy to San Francisco?

The best pricing can be found in the month of March. Prices to San Francisco from Italy average $688. You can even find prices in March for less than $688, as users have found deals to San Francisco from as low as $440. The month of July appears to be one of the more expensive times to travel to San Francisco from Italy. Flying in the targeted month can save you up to 26%.

What airport do you fly into for flights to San Francisco from Italy?

Located just 11.8 mi from the city center, San Francisco (SFO) is the airport most travelers will use when flying to San Francisco from Italy.

Can I find deals for flights from Italy to San Francisco that include hotel bookings?

Yes. In addition to deals on Italy to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Italy to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to San Francisco.

Can I find deals for business class flights from Italy to San Francisco?

Yes. Cheapflights offers flight deals from Italy to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$572+ Flights from Italy to San Francisco - Compare & Save Big

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Cheap flight deals from Italy to San Francisco

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$538 (Booking.com)
One-way from	$305 (Kiwi.com)
Popular in	July
Cheapest in	March
Average price	$645
Good round-trip deal	$673 or less
Good one-way deal	$712 or less

Provider with most accurate pricing for Rome (ROM)-San Francisco flight deals.

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Provider most trusted by Cheapflights users for Rome (ROM)-San Francisco flights.

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From Italy to San Francisco

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One-way flight from Italy to San Francisco

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Highest demand for flights based on searches. 14% potential increase in price ($112 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).

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Average for round-trip flights in May 2025

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Price to beat on a round-trip flight from Italy to San Francisco.

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Price to beat on a one-way flight from Italy to San Francisco.

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Find flight deals from Italy to San Francisco

Cheapest flights from Italy to San Francisco
Explore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Thu 5/157:50 amBLQ - SFO

1 stop18h 25mBritish Airways

Mon 5/197:30 pmSFO - BLQ

1 stop19h 15mBritish Airways

Deal found 4/30

$538

Fri 8/299:50 amVCE - SFO

2 stops22h 07mMultiple Airlines

Fri 10/34:35 pmSFO - VCE

1 stop20h 40mMultiple Airlines

Deal found 4/30

$540

Mon 8/2512:15 pmVCE - SFO

1 stop20h 13mBritish Airways

Sun 9/74:35 pmSFO - VCE

1 stop18h 45mBritish Airways

Deal found 4/30

$541

Fri 9/1912:00 pmNAP - SFO

1 stop18h 49mBritish Airways

Sun 9/284:35 pmSFO - NAP

1 stop20h 25mBritish Airways

Deal found 4/30

$543

Tue 8/269:40 amBLQ - SFO

2 stops20h 11mMultiple Airlines

Thu 9/411:59 pmSFO - BLQ

2 stops33h 31mMultiple Airlines

Deal found 4/30

$543

Thu 5/812:15 pmVCE - SFO

1 stop18h 50mAmerican Airlines

Thu 5/224:20 pmSFO - VCE

1 stop19h 15mAmerican Airlines

Deal found 4/30

$545

Fri 5/93:00 pmNAP - SFO

1 stop28h 36mAmerican Airlines

Sat 5/2411:05 pmSFO - NAP

1 stop25h 55mAmerican Airlines

Deal found 4/30

$551

Sun 6/89:00 amMXP - SFO

1 stop14h 30mCondor

Wed 7/164:30 pmSFO - MXP

1 stop14h 45mCondor

Deal found 4/30

$555

Thu 5/87:25 amLIN - SFO

2 stops18h 34mBritish Airways

Thu 5/297:30 pmSFO - LIN

1 stop17h 20mBritish Airways

Deal found 4/30

$558

Wed 5/711:10 amMXP - SFO

1 stop18h 25mAmerican Airlines

Sun 6/111:05 pmSFO - MXP

1 stop27h 15mAmerican Airlines

Deal found 4/30

$558

Sun 5/49:00 amMXP - SFO

1 stop14h 30mMultiple Airlines

Tue 5/209:25 amSFO - MXP

2 stops21h 50mMultiple Airlines

Deal found 4/30

$559

Sun 10/269:25 pmMXP - SFO

1 stop26h 35mBritish Airways

Sun 11/910:39 pmSFO - MXP

1 stop24h 31mBritish Airways

Deal found 4/30

$566

Best flights from Italy to San Francisco
Discover carefully curated flight deals from Italy to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2025.

Thu 5/157:50 amBLQ - SFO

1 stop18h 25mBritish Airways

Mon 5/197:30 pmSFO - BLQ

1 stop19h 15mBritish Airways

Deal found 4/30

$538

Fri 8/299:50 amVCE - SFO

2 stops22h 07mMultiple Airlines

Fri 10/34:35 pmSFO - VCE

1 stop20h 40mMultiple Airlines

Deal found 4/30

$540

Sun 6/89:00 amMXP - SFO

1 stop14h 30mCondor

Wed 7/164:30 pmSFO - MXP

1 stop14h 45mCondor

Deal found 4/30

$555

Sun 5/1111:10 amMXP - SFO

1 stop21h 56mAmerican Airlines

Sun 6/111:05 pmSFO - MXP

1 stop27h 15mAmerican Airlines

Deal found 4/30

$558

Sun 10/2611:00 amMXP - SFO

2 stops18h 25mFinnair

Wed 11/1210:25 amSFO - MXP

1 stop36h 45mFinnair

Deal found 4/30

$587

Tue 9/1611:50 amFLR - SFO

1 stop35h 45mTAP AIR PORTUGAL

Wed 10/295:35 pmSFO - FLR

1 stop16h 55mTAP AIR PORTUGAL

Deal found 5/1

$594

Thu 9/189:15 amMXP - SFO

1 stop16h 15mScandinavian Airlines

Wed 10/87:40 pmSFO - MXP

1 stop14h 35mScandinavian Airlines

Deal found 5/1

$594

Tue 10/79:00 pmLIN - SFO

1 stop25h 15mITA Airways

Wed 10/153:15 pmSFO - LIN

1 stop16h 55mITA Airways

Deal found 5/1

$596

Thu 5/159:05 amNAP - SFO

1 stop35h 40mKLM

Wed 5/288:25 pmSFO - NAP

1 stop16h 40mKLM

Deal found 4/30

$658

Tue 8/266:00 amBLQ - SFO

1 stop14h 45mDelta

Thu 9/411:05 amSFO - BLQ

2 stops21h 00mDelta

Deal found 5/1

$658

Fri 10/246:50 amMXP - SFO

1 stop15h 00mAir France

Fri 10/319:00 amSFO - MXP

1 stop15h 45mAir France

Deal found 4/30

$679

Sat 6/148:40 pmNAP - SFO

1 stop22h 55mTurkish Airlines

Sun 6/2212:40 pmSFO - NAP

1 stop34h 40mTurkish Airlines

Deal found 4/30

$683

Last-minute flights from Italy to San Francisco
Discover last-minute flight deals from Italy to San Francisco. Data last updated May 1, 2025 and is based on user searches.

Fri 5/29:00 amMXP - SFO

1 stop14h 30mCondor

Fri 5/94:30 pmSFO - MXP

1 stop14h 45mCondor

Deal found 4/30

$583

Sun 5/49:00 amMXP - SFO

1 stop14h 30mMultiple Airlines

Tue 5/209:25 amSFO - MXP

2 stops21h 50mMultiple Airlines

Deal found 4/30

$559

Tue 5/66:15 amVCE - SFO

2 stops23h 37mITA Airways

Sat 5/1011:12 amSFO - VCE

2 stops18h 18mITA Airways

Deal found 5/1

$666

Tue 5/68:20 amFCO - SFO

2 stops24h 14mMultiple Airlines

Tue 5/138:00 amSFO - FCO

2 stops23h 55mMultiple Airlines

Deal found 4/29

$680

Tue 5/69:20 amVCE - SFO

1 stop34h 15mTurkish Airlines

Sat 5/1012:40 pmSFO - VCE

1 stop34h 40mTurkish Airlines

Deal found 4/30

$685

Wed 5/711:00 amLIN - SFO

2 stops18h 01mDelta

Wed 5/2811:15 amSFO - LIN

2 stops17h 40mDelta

Deal found 4/30

$669

Wed 5/710:55 pmLIN - SFO

1 stop21h 50mKLM

Fri 5/301:45 pmSFO - LIN

1 stop35h 20mKLM

Deal found 4/30

$701

Wed 5/711:10 amMXP - SFO

1 stop18h 25mBritish Airways

Fri 5/3010:20 pmSFO - MXP

1 stop25h 50mBritish Airways

Deal found 4/30

$710

Wed 5/711:10 amMXP - SFO

1 stop18h 25mAmerican Airlines

Sat 5/3110:20 pmSFO - MXP

1 stop25h 50mAmerican Airlines

Deal found 4/30

$558

Wed 5/77:50 amLIN - SFO

2 stops20h 47mAmerican Airlines

Thu 5/295:45 pmSFO - LIN

1 stop16h 50mAmerican Airlines

Deal found 4/30

$584

Wed 5/711:10 amMXP - SFO

1 stop21h 56mFinnair

Mon 5/267:30 pmSFO - MXP

2 stops29h 35mFinnair

Deal found 4/30

$591

Thu 5/86:50 amBLQ - SFO

2 stops21h 47mMultiple Airlines

Thu 5/224:20 pmSFO - BLQ

1 stop22h 35mMultiple Airlines

Deal found 4/30

$668

One-way flights from Italy to San Francisco
Search for one-way flight options from Italy to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 1, 2025.

Fri 5/98:00 amTSF - SFO

2 stops45h 27mMultiple Airlines

Deal found 4/30

$305

Mon 6/96:50 amBGY - SFO

2 stops57h 41mMultiple Airlines

Deal found 5/1

$322

Mon 6/97:00 amNAP - SFO

2 stops57h 31mMultiple Airlines

Deal found 4/30

$324

Wed 6/48:40 pmVCE - SFO

1 stop26h 10mMultiple Airlines

Deal found 5/1

$329

Sun 6/87:15 pmFLR - SFO

1 stop28h 15mTAP AIR PORTUGAL

Deal found 4/30

$337

Thu 6/57:15 pmNAP - SFO

1 stop27h 20mTAP AIR PORTUGAL

Deal found 4/30

$340

Mon 5/1210:30 pmVCE - SFO

1 stop28h 30mVueling

Deal found 4/29

$365

Wed 5/77:05 pmVCE - SFO

1 stop28h 25mTAP AIR PORTUGAL

Deal found 4/30

$391

Wed 5/286:25 amFLR - SFO

2 stops22h 25mMultiple Airlines

Deal found 4/30

$399

Mon 6/98:15 pmMXP - SFO

2 stops29h 30mTAP AIR PORTUGAL

Deal found 4/30

$410

Sun 6/159:00 pmLIN - SFO

2 stops55h 43mMultiple Airlines

Deal found 5/1

$427

Fri 9/56:55 pmTRN - SFO

1 stop32h 15mVueling

Deal found 4/29

$433

Cheapflights Fare Finder

Use the filters below to find and compare flights from Italy to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BolognaSan Francisco

BLQ - SFO

BLQSFO

Bologna Guglielmo Marconi

Thu 5/15

7:50 am-5:15 pm

1 stop18h 25m

San Francisco

Mon 5/19

7:30 pm-11:45 pm

1 stop19h 15m

$538

VeniceSan Francisco

VCE - SFO

VCESFO

Venice Marco Polo

Fri 8/29

9:50 am-10:57 pm

2 stops22h 07m

San Francisco

Fri 10/3

4:35 pm-10:15 pm

1 stop20h 40m

$540

VeniceSan Francisco

VCE - SFO

VCESFO

Venice Marco Polo

Mon 8/25

12:15 pm-11:28 pm

1 stop20h 13m

San Francisco

Sun 9/7

4:35 pm-8:20 pm

1 stop18h 45m

$541

BolognaSan Francisco

BLQ - SFO

BLQSFO

Bologna Guglielmo Marconi

Tue 8/26

9:40 am-8:51 pm

2 stops20h 11m

San Francisco

Thu 9/4

11:59 pm-6:30 pm

2 stops33h 31m

$543

NaplesSan Francisco

NAP - SFO

NAPSFO

Naples

Fri 9/19

12:00 pm-9:49 pm

1 stop18h 49m

San Francisco

Sun 9/28

4:19 pm-10:00 pm

2 stops20h 41m

$543

MilanSan Francisco

MXP - SFO

MXPSFO

Milan Malpensa

Sun 6/8

9:00 am-2:30 pm

1 stop14h 30m

San Francisco

Wed 7/16

4:30 pm-4:15 pm

1 stop14h 45m

$555

MilanSan Francisco

MXP - SFO

MXPSFO

Milan Malpensa

Sun 5/11

11:10 am-12:06 am

1 stop21h 56m

San Francisco

Sun 6/1

11:05 pm-11:20 am

1 stop27h 15m

$558

MilanSan Francisco

MXP - SFO

MXPSFO

Milan Malpensa

Wed 5/21

9:00 am-2:30 pm

1 stop14h 30m

San Francisco

Wed 5/28

9:25 am-4:15 pm

2 stops21h 50m

$580

MilanSan Francisco

MXP - SFO

MXPSFO

Milan Malpensa

Sun 10/26

11:00 am-9:25 pm

2 stops18h 25m

San Francisco

Wed 11/12

10:25 am-8:10 am

1 stop36h 45m

$587

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Tue 9/16

11:50 am-2:35 pm

1 stop35h 45m

San Francisco

Wed 10/29

5:35 pm-6:30 pm

1 stop16h 55m

$594

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 60 results

...

Best time to book a flight from Italy to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Italy with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to San Francisco

What is the cheapest month to book a flight from Italy to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Italy to San Francisco (average of $276). Flying from Italy to San Francisco in June is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IT to SFO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Italy to San Francisco as you normally would.

Rainfall in San Francisco by month

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Delta, Emirates and KLM from Italy to San Francisco by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,934 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Emirates

8.0

Very good

3,217 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

KLM

7.8

Good

1,334 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Austrian Airlines

7.6

Good

781 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Finnair

7.6

Good

1,275 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What airport do you fly into for flights to San Francisco from Italy?
Located just 11.8 mi from the city center, San Francisco (SFO) is the airport most travelers will use when flying to San Francisco from Italy.
What are the cheapest airlines to fly from Italy to San Francisco one-way?
One-way options have recently been found by users for as low as $337 on TAP AIR PORTUGAL. Other airlines that offer cheap prices include Vueling from $365 and Iberia from $436 one-way.
What are the most popular routes from Italy to San Francisco?
The most popular route from Italy to San Francisco is Rome Fiumicino - San Francisco. You may also consider Milan Malpensa - San Francisco or Milan Linate - San Francisco.
Can I find deals for flights from Italy to San Francisco that include hotel bookings?
Yes. In addition to deals on Italy to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Italy to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to San Francisco.
Can I find deals for business class flights from Italy to San Francisco?
Yes. Cheapflights offers flight deals from Italy to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Italy to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Italy to San Francisco (average of $276). Flying from Italy to San Francisco in June is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

Mountain View

Santa Cruz

Livermore

South San Francisco

Turlock

Manteca

Fairfield

Richmond

Watsonville

Hollister

Newark

Milpitas

Antioch

Sausalito

Hayward

Alameda

Sunnyvale

Campbell

Daly City

Browse thousands of different options on Cheapflights for your next trip

Top 7 airlines flying from Italy to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
TAP AIR PORTUGAL	Cheapest$426	Average$573	FlexibilityNo cancel fee	On-timeN/A
ITA Airways	Cheapest$484	Average$907	FlexibilityNo cancel fee	On-time81%
United Airlines	Cheapest$517	Average$726	FlexibilityNo cancel fee	On-time69%
Iberia	Cheapest$542	Average$561	FlexibilityNo cancel fee	On-time77%
British Airways	Cheapest$552	Average$780	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$555	Average$731	FlexibilityNo cancel fee	On-time71%
Lufthansa	Cheapest$570	Average$739	FlexibilityNo cancel fee	On-time76%

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$305+ Cheap flights from Italy to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Italy to San Francisco with Cheapflights

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Cheap flight deals from Italy to San Francisco

Keep the following information in mind while searching for Italy to San Francisco flight deals. Data was last updated May 1, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Italy to San Francisco

Cheapest flights from Italy to San FranciscoExplore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Explore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Italy to San Francisco that are best for you.

Best time to book a flight from Italy to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Italy with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Italy to San Francisco

What is the cheapest month to book a flight from Italy to San Francisco?

What is the cheapest time of day to fly from IT to SFO?

Find hourly flight availability from Italy to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Delta, Emirates and KLM from Italy to San Francisco by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Italy to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to San Francisco from Italy?

What are the cheapest airlines to fly from Italy to San Francisco one-way?

What are the most popular routes from Italy to San Francisco?

Can I find deals for flights from Italy to San Francisco that include hotel bookings?

How can I find direct flights from Italy to San Francisco?

Can I find deals for business class flights from Italy to San Francisco?

What is the cheapest month to book a flight from Italy to San Francisco?

Traveling to a place near Italy?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Italy to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Italy to San Francisco

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Cheapest flights from Italy to San Francisco
Explore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.