What’s the cheapest layover airport for flights from Fort Myers to San Francisco?

St. Louis (STL) is the most affordable 1-stop option, with an average round-trip price of $362.

Which airport typically offers the quickest layover for flights from Fort Myers to San Francisco?

Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 24m.

What’s the fastest layover option from Fort Myers to San Francisco?

Flights via St. Louis (STL) have the shortest average one-way travel time for 1-stop routes: 9h 06m.

What’s the top layover airport for flights from Fort Myers to San Francisco?

Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from Fort Myers to San Francisco on Cheapflights.

How popular is this Fort Myers to San Francisco flight route?

Within the past month, 1 users have taken a look at flights from Fort Myers SW Florida Intl to San Francisco.

How long is the flight from Fort Myers to San Francisco?

There are many flights that can get you from Fort Myers to San Francisco in 12h 49m. Fly via JetBlue or Delta to get the fastest option. The distance between Fort Myers and San Francisco is about 2475 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Fort Myers to San Francisco round-trip?

Flying on American Airlines is currently your cheapest option to San Francisco, with prices starting at $204. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $256 and $256, respectively. American Airlines is currently priced 47% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Fort Myers to San Francisco one-way?

One-way options have recently been found by users for as low as $102 on American Airlines. Other airlines that offer cheap prices include Delta from $132 and United Airlines from $156 one-way.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What are the cheapest flights from Fort Myers to San Francisco?

While on average a flight from Fort Myers to San Francisco is generally $391, our data shows the cheapest flight currently is $158. When looking at the most popular route, (Fort Myers SW Florida Intl - San Francisco), you can expect to pay $263 for that flight.

What are the most popular airlines that fly from Fort Myers to San Francisco?

American Airlines, United Airlines and Delta are the most popular airlines when flying from Fort Myers to San Francisco.

Most accurate provider : When it comes to deals on Fort Myers-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Fort Myers-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Fort Myers-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Fort Myers-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Fort Myers to San Francisco?

To fly from Fort Myers to San Francisco, you need to book a flight from SW Florida Intl (RSW) to San Francisco (SFO). Nonstop flights to San Francisco from Fort Myers SW Florida Intl take 6h 19m on average. When it comes time to book airfare, you have a few options: there is 1 outbound flight from SW Florida Intl to San Francisco offered by 4 different airlines.

Can I find deals for flights from Fort Myers to San Francisco that include hotel bookings?

Yes. In addition to deals on Fort Myers to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Fort Myers to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to San Francisco.

Can I find deals for business class flights from Fort Myers to San Francisco?

Yes. Cheapflights offers flight deals from Fort Myers to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$107+ Flights from Fort Myers to San Francisco

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to San Francisco are usually found in July or June, booked 49 days in advance, depart on a Wednesday or Sunday and return on a Tuesday

Cheap flight deals from Fort Myers to San Francisco

Cheapest flights from Fort Myers to San Francisco
Explore the most affordable flight options available from Fort Myers to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Fri 12/268:30 amRSW - SFO

Nonstop6h 19mUnited Airlines

Tue 12/301:15 pmSFO - RSW

Nonstop5h 14mUnited Airlines

Deal found 12/9

$347

Wed 12/242:01 pmRSW - SFO

1 stop9h 49mDelta

Sat 1/1712:04 pmSFO - RSW

1 stop8h 23mDelta

Deal found 12/9

$349

Sat 12/203:35 pmRSW - SFO

1 stop9h 54mDelta

Sun 1/410:45 pmSFO - RSW

1 stop9h 53mDelta

Deal found 12/11

$414

Wed 12/248:30 amRSW - SFO

Nonstop6h 19mUnited Airlines

Sat 1/178:25 amSFO - RSW

Nonstop5h 20mUnited Airlines

Deal found 12/9

$429

Sat 12/201:51 pmRSW - SFO

1 stop10h 00mAmerican Airlines

Sat 1/36:00 amSFO - RSW

1 stop9h 18mAmerican Airlines

Deal found 12/11

$438

Mon 12/228:05 amRSW - SFO

1 stop10h 54mUnited Airlines

Sun 12/2812:30 amSFO - RSW

1 stop7h 10mUnited Airlines

Deal found 12/10

$454

Thu 12/258:30 amRSW - SFO

Nonstop6h 19mUnited Airlines

Mon 12/291:15 pmSFO - RSW

Nonstop5h 14mUnited Airlines

Deal found 12/10

$469

Best flights from Fort Myers to San Francisco
Discover carefully curated flight deals from Fort Myers to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Wed 1/148:30 amRSW - SFO

1 stop13h 25mJetBlue

Tue 1/208:37 pmSFO - RSW

1 stop11h 13mJetBlue

Deal found 12/10

$263

Wed 1/148:00 amRSW - SFO

2 stops12h 49mDelta

Wed 1/287:00 pmSFO - RSW

2 stops11h 50mDelta

Deal found 12/10

$274

Wed 1/75:02 pmRSW - SFO

1 stop9h 57mUnited Airlines

Sat 1/178:25 amSFO - RSW

Nonstop5h 20mUnited Airlines

Deal found 12/10

$295

Sat 1/176:32 amRSW - SFO

1 stop10h 15mDelta

Sat 1/246:30 pmSFO - RSW

2 stops12h 30mDelta

Deal found 12/9

$291

Sat 1/172:35 pmRSW - SFO

1 stop9h 55mUnited Airlines

Sat 1/248:25 amSFO - RSW

Nonstop5h 20mUnited Airlines

Deal found 12/9

$299

Wed 1/148:00 amRSW - SFO

2 stops12h 49mDelta

Tue 1/2011:40 amSFO - RSW

1 stop6h 58mDelta

Deal found 12/10

$291

Wed 1/75:02 pmRSW - SFO

1 stop9h 57mUnited Airlines

Wed 1/145:00 amSFO - RSW

1 stop7h 20mUnited Airlines

Deal found 12/10

$304

Last-minute flights from Fort Myers to San Francisco
Discover last-minute flight deals from Fort Myers to San Francisco. Data last updated December 12, 2025 and is based on user searches.

Wed 1/75:47 pmRSW - SFO

Nonstop6h 21mUnited Airlines

Sat 1/178:25 amSFO - RSW

Nonstop5h 20mUnited Airlines

Deal found 12/10

$289

Wed 1/77:00 amRSW - SFO

1 stop8h 20mUnited Airlines

Wed 1/148:25 amSFO - RSW

Nonstop5h 20mUnited Airlines

Deal found 12/10

$299

Sat 1/109:00 amRSW - SFO

1 stop9h 50mHawaiian Airlines

Sat 1/177:00 amSFO - RSW

1 stop11h 11mHawaiian Airlines

Deal found 12/11

$288

Tue 1/1312:10 pmRSW - SFO

1 stop12h 10mMultiple Airlines

Sat 1/177:00 amSFO - RSW

1 stop11h 11mMultiple Airlines

Deal found 12/10

$281

Wed 1/1412:10 pmRSW - SFO

1 stop12h 10mMultiple Airlines

Thu 1/1511:20 pmSFO - RSW

1 stop10h 09mMultiple Airlines

Deal found 12/11

$225

Wed 1/148:30 amRSW - SFO

1 stop12h 24mJetBlue

Tue 1/208:37 pmSFO - RSW

1 stop11h 13mJetBlue

Deal found 12/9

$263

Wed 1/148:00 amRSW - SFO

2 stops12h 49mDelta

Wed 1/287:00 pmSFO - RSW

2 stops11h 50mDelta

Deal found 12/9

$274

Wed 1/1412:55 pmRSW - SFO

2 stops13h 33mDelta

Tue 1/2011:40 amSFO - RSW

1 stop6h 58mDelta

Deal found 12/9

$301

Sun 1/259:00 amRSW - SFO

1 stop9h 50mAlaska Airlines

Fri 1/307:00 amSFO - RSW

1 stop11h 11mAlaska Airlines

Deal found 12/10

$307

One-way flights from Fort Myers to San Francisco
Search for one-way flight options from Fort Myers to San Francisco. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Sun 1/117:31 amRSW - SFO

2 stops27h 32mMultiple Airlines

Deal found 12/9

$107

Mon 1/127:25 pmRSW - SFO

1 stop20h 59mFrontier

Deal found 12/10

$119

Fri 2/276:00 amRSW - SFO

2 stops31h 50mMultiple Airlines

Deal found 12/10

$131

Mon 1/127:25 pmRSW - SFO

3 stops30h 42mMultiple Airlines

Deal found 12/10

$132

Tue 3/36:00 amRSW - SFO

3 stops45h 28mMultiple Airlines

Deal found 12/11

$139

Sun 1/187:31 amRSW - SFO

3 stops32h 53mMultiple Airlines

Deal found 12/10

$150

Tue 3/312:33 pmRSW - SFO

2 stops45h 47mFrontier

Deal found 12/11

$153

Sat 1/179:00 amRSW - SFO

1 stop11h 59mAlaska Airlines

Deal found 12/10

$154

Sat 2/211:02 pmRSW - SFO

1 stop11h 53mFrontier

Deal found 12/11

$168

Find flight deals from Fort Myers to San Francisco

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$225 (Expedia)
One-way from	$107 (Kiwi.com)
Popular in	October
Cheapest in	July
Average price	$447

Provider with most accurate pricing for Fort Myers SW Florida Intl-San Francisco flight deals.

Search Deals

Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-San Francisco flights.

Search Deals

From Fort Myers SW Florida Intl to San Francisco

Search Deals

One-way flight from Fort Myers SW Florida Intl to San Francisco

Search Deals

Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersSan Francisco

RSW - SFO

RSWSFO

Fort Myers SW Florida Intl

Wed 1/14

8:30 am-6:55 pm

1 stop13h 25m

San Francisco

Tue 1/20

8:37 pm-10:50 am

1 stop11h 13m

$263

Fort MyersSan Francisco

RSW - SFO

RSWSFO

Fort Myers SW Florida Intl

Wed 1/14

8:00 am-5:49 pm

2 stops12h 49m

San Francisco

Wed 1/28

7:00 pm-9:50 am

2 stops11h 50m

$274

Fort MyersSan Francisco

RSW - SFO

RSWSFO

Fort Myers SW Florida Intl

Sat 1/17

6:32 am-1:47 pm

1 stop10h 15m

San Francisco

Sat 1/24

6:30 pm-10:00 am

2 stops12h 30m

$291

Fort MyersSan Francisco

RSW - SFO

RSWSFO

Fort Myers SW Florida Intl

Wed 1/14

8:00 am-5:49 pm

2 stops12h 49m

San Francisco

Tue 1/20

11:40 am-9:38 pm

1 stop6h 58m

$291

Fort MyersSan Francisco

RSW - SFO

RSWSFO

Fort Myers SW Florida Intl

Wed 1/7

5:02 pm-11:59 pm

1 stop9h 57m

San Francisco

Sat 1/17

8:25 am-4:45 pm

Nonstop5h 20m

$295

Fort MyersSan Francisco

RSW - SFO

RSWSFO

Fort Myers SW Florida Intl

Sat 1/17

2:35 pm-9:30 pm

1 stop9h 55m

San Francisco

Sat 1/24

8:25 am-4:45 pm

Nonstop5h 20m

$299

Fort MyersSan Francisco

RSW - SFO

RSWSFO

Fort Myers SW Florida Intl

Wed 1/7

5:02 pm-11:59 pm

1 stop9h 57m

San Francisco

Wed 1/14

5:00 am-3:20 pm

1 stop7h 20m

$304

Fort MyersSan Francisco

RSW - SFO

RSWSFO

Fort Myers SW Florida Intl

Thu 2/26

7:45 pm-5:58 pm

2 stops25h 13m

$127

Fort MyersSan Francisco

RSW - SFO

RSWSFO

Fort Myers SW Florida Intl

Mon 1/26

12:10 pm-10:49 pm

1 stop13h 39m

$137

Fort MyersSan Francisco

RSW - SFO

RSWSFO

Fort Myers SW Florida Intl

Sat 1/17

8:00 am-5:49 pm

2 stops12h 49m

$137

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 19 results

Compare providers for flights from Fort Myers to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to San Francisco in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
JustAirTicket	Price Accuracy-	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Fort Myers-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Fort Myers-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Fort Myers-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Fort Myers-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Fort Myers with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to San Francisco

Prices

How far ahead should I book a flight from Fort Myers to San Francisco?

To ensure you get the cheapest price possible for a flight from Fort Myers to San Francisco, you should look to book at least 49 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Fort Myers to San Francisco?

Currently, July is the cheapest month in which you can book a flight from Fort Myers to San Francisco (average of $136). Flying from Fort Myers to San Francisco in March is currently the most expensive (average of $260). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to SFO?

When flying from Fort Myers to San Francisco, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 61% versus a flight in the afternoon.

What is the cheapest day to fly from Fort Myers to San Francisco?

Travelers seeking maximum savings on their Fort Myers to San Francisco flight should consider departing on Monday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Fort Myers to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

7.9

Good

4,253 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

7.9

Good

8,008 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

9,095 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

11,050 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

What airports do I use to fly from Fort Myers to San Francisco?
To fly from Fort Myers to San Francisco, you need to book a flight from SW Florida Intl (RSW) to San Francisco (SFO). Nonstop flights to San Francisco from Fort Myers SW Florida Intl take 6h 19m on average. When it comes time to book airfare, you have a few options: there is 1 outbound flight from SW Florida Intl to San Francisco offered by 4 different airlines.
How popular is this Fort Myers to San Francisco flight route?
Within the past month, 1 users have taken a look at flights from Fort Myers SW Florida Intl to San Francisco.
How long is the flight from Fort Myers to San Francisco?
There are many flights that can get you from Fort Myers to San Francisco in 12h 49m. Fly via JetBlue or Delta to get the fastest option. The distance between Fort Myers and San Francisco is about 2475 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Fort Myers to San Francisco round-trip?
Flying on American Airlines is currently your cheapest option to San Francisco, with prices starting at $204. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $256 and $256, respectively. American Airlines is currently priced 47% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Fort Myers to San Francisco one-way?
One-way options have recently been found by users for as low as $102 on American Airlines. Other airlines that offer cheap prices include Delta from $132 and United Airlines from $156 one-way.
What are the cheapest flights from Fort Myers to San Francisco?
While on average a flight from Fort Myers to San Francisco is generally $391, our data shows the cheapest flight currently is $158. When looking at the most popular route, (Fort Myers SW Florida Intl - San Francisco), you can expect to pay $263 for that flight.
Can I find deals for flights from Fort Myers to San Francisco that include hotel bookings?
Yes. In addition to deals on Fort Myers to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to San Francisco.
Can I find deals for business class flights from Fort Myers to San Francisco?
Yes. Cheapflights offers flight deals from Fort Myers to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Fort Myers to San Francisco?
Currently, July is the cheapest month in which you can book a flight from Fort Myers to San Francisco (average of $136). Flying from Fort Myers to San Francisco in March is currently the most expensive (average of $260). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 4 airlines flying from Fort Myers to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$204	Average$367	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$256	Average$339	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$259	Average$445	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$264	Average$458	FlexibilityNo cancel fee	On-time63%

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$107+ Cheap flights from Fort Myers to San Francisco (RSW - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to San Francisco are usually found in July or June, booked 49 days in advance, depart on a Wednesday or Sunday and return on a Tuesday

Cheap flight deals from Fort Myers to San Francisco

Cheapest flights from Fort Myers to San FranciscoExplore the most affordable flight options available from Fort Myers to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Fort Myers to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Fort Myers to San Francisco

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to San Francisco that are best for you.

Compare providers for flights from Fort Myers to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to San Francisco in December.

Best time to book a flight from Fort Myers to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Fort Myers with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to San Francisco

How far ahead should I book a flight from Fort Myers to San Francisco?

What is the cheapest month to book a flight from Fort Myers to San Francisco?

What is the cheapest time of day to fly from RSW to SFO?

What is the cheapest day to fly from Fort Myers to San Francisco?

What’s the top layover airport for flights from Fort Myers to San Francisco?

What’s the cheapest layover airport for flights from Fort Myers to San Francisco?

What’s the fastest layover option from Fort Myers to San Francisco?

Which airport typically offers the quickest layover for flights from Fort Myers to San Francisco?

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Fort Myers to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Fort Myers to San Francisco?

How popular is this Fort Myers to San Francisco flight route?

How long is the flight from Fort Myers to San Francisco?

What are the cheapest airlines flying from Fort Myers to San Francisco round-trip?

What are the cheapest airlines to fly from Fort Myers to San Francisco one-way?

What are the cheapest flights from Fort Myers to San Francisco?

Can I find deals for flights from Fort Myers to San Francisco that include hotel bookings?

How can I find direct flights from Fort Myers to San Francisco?

Can I find deals for business class flights from Fort Myers to San Francisco?

What is the cheapest month to book a flight from Fort Myers to San Francisco?

Traveling to a place near San Francisco?

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Alternative routes for Fort Myers to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Fort Myers to San Francisco

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Cheapest flights from Fort Myers to San Francisco
Explore the most affordable flight options available from Fort Myers to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.