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$224+ Cheap flights from Mexico City (TLC) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
TLC — SAN
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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1. Tell us where you want to go

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Cheap flight deals from Mexico City to San Diego

Cheapest flights from Mexico City to San Diego
Explore the most affordable flight options available from Mexico City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Trip.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:25 pm
TLC
-
SAN
1 stop6h 41m
Multiple Airlines
Sun 4/269:15 am
SAN
-
TLC
1 stop6h 45m
Multiple Airlines
Deal found 1/27$455
This Trip.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:26 am
TLC
-
SAN
2 stops8h 53m
Multiple Airlines
Wed 3/119:15 am
SAN
-
TLC
2 stops13h 43m
Multiple Airlines
Deal found 1/28$459
This Trip.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:45 am
TLC
-
SAN
2 stops37h 04m
Multiple Airlines
Sun 3/812:49 pm
SAN
-
TLC
2 stops18h 36m
Multiple Airlines
Deal found 1/28$528
This Trip.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:45 am
TLC
-
SAN
1 stop6h 28m
Multiple Airlines
Mon 5/410:25 am
SAN
-
TLC
2 stops22h 35m
Multiple Airlines
Deal found 1/27$555
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:00 am
TLC
-
SAN
2 stops18h 40m
Multiple Airlines
Sat 3/2112:42 pm
SAN
-
TLC
1 stop24h 19m
Multiple Airlines
Deal found 1/28$566
This Trip.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2710:45 am
TLC
-
SAN
2 stops25h 04m
Multiple Airlines
Sun 3/112:49 pm
SAN
-
TLC
2 stops19h 11m
Multiple Airlines
Deal found 1/28$582
This eDestinos deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:26 am
TLC
-
SAN
2 stops23h 56m
Multiple Airlines
Sun 5/312:14 pm
SAN
-
TLC
1 stop26h 01m
Multiple Airlines
Deal found 1/27$598
This Trip.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/298:26 am
TLC
-
SAN
2 stops9h 48m
Multiple Airlines
Sun 4/59:10 am
SAN
-
TLC
2 stops13h 48m
Multiple Airlines
Deal found 1/28$635

Find flight deals from Mexico City to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (TLC) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$455
(Trip.com)

One-way from

$224
(Trip.com)

Popular in

January

Cheapest in

December

Average price

$655
Provider with most accurate pricing for Mexico City Toluca Intl-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Toluca Intl-San Diego flights.
Search Deals
From Mexico City Toluca Intl to San Diego
Search Deals
One-way flight from Mexico City Toluca Intl to San Diego
Search Deals
High demand for flights, 5% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Mexico City to San Diego that are best for you.

Fly from

Mexico City

Fly to

San Diego

Route

Depart

Return

Price

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Wed 4/22

12:25 pm-6:06 pm

1 stop6h 41m

San Diego

Sun 4/26

9:15 am-5:00 pm

1 stop6h 45m

$455

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Sat 3/7

8:26 am-3:19 pm

2 stops8h 53m

San Diego

Wed 3/11

9:15 am-11:58 pm

2 stops13h 43m

$459

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Fri 3/6

10:45 am-9:49 pm

2 stops37h 04m

San Diego

Sun 3/8

12:49 pm-8:25 am

2 stops18h 36m

$528

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Fri 5/1

10:45 am-4:13 pm

1 stop6h 28m

San Diego

Mon 5/4

10:25 am-10:00 am

2 stops22h 35m

$555

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Sat 3/14

6:00 am-11:40 pm

2 stops18h 40m

San Diego

Sat 3/21

12:42 pm-2:01 pm

1 stop24h 19m

$566

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Fri 2/27

10:45 am-9:49 am

2 stops25h 04m

San Diego

Sun 3/1

12:49 pm-10:00 am

2 stops19h 11m

$582

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Fri 5/29

8:26 am-7:22 am

2 stops23h 56m

San Diego

Sun 5/31

2:14 pm-5:15 pm

1 stop26h 01m

$598

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Thu 5/14

8:26 am-5:40 pm

2 stops10h 14m

$224

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Wed 3/18

10:45 am-4:21 pm

1 stop6h 36m

$247

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Sun 5/24

3:05 pm-7:39 am

3 stops41h 34m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 15 results
1
2

Compare providers for flights from Mexico City to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mexico City to San Diego in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Mexico City-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Mexico City-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Mexico City-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mexico City-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mexico City to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to San Diego

What is the cheapest month to book a flight from Mexico City to San Diego?

Currently, November is the cheapest month in which you can book a flight from Mexico City to San Diego (average of $114). Flying from Mexico City to San Diego in March is currently the most expensive (average of $391). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Mexico City to San Diego that include hotel bookings?

    Yes. In addition to deals on Mexico City to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to San Diego.

  • Can I find deals for business class flights from Mexico City to San Diego?

    Yes. Cheapflights offers flight deals from Mexico City to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to San Diego?

    Currently, November is the cheapest month in which you can book a flight from Mexico City to San Diego (average of $114). Flying from Mexico City to San Diego in March is currently the most expensive (average of $391). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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