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$217+ Cheap flights from Mexico City (TLC) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
TLC — SAN
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Mexico City to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (TLC) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$377
(Trip.com)

One-way from

$217
(Trip.com)

Popular in

June

Cheapest in

October

Average price

$553
From Mexico City Toluca Intl to San Diego
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One-way flight from Mexico City Toluca Intl to San Diego
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Highest demand for flights based on searches. 1% potential increase in price ($8 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mexico City to San Diego

Cheapest flights from Mexico City to San Diego
Explore the most affordable flight options available from Mexico City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Trip.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1112:10 pmTLC - SAN
1 stop7h 05mMultiple Airlines
Tue 10/148:10 amSAN - TLC
1 stop7h 55mMultiple Airlines
Deal found 9/9$377
This Trip.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1012:10 pmTLC - SAN
1 stop7h 05mMultiple Airlines
Fri 10/178:10 amSAN - TLC
1 stop7h 55mMultiple Airlines
Deal found 9/11$443
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1712:10 pmTLC - SAN
1 stop7h 05mMultiple Airlines
Fri 10/248:10 amSAN - TLC
1 stop7h 55mMultiple Airlines
Deal found 9/10$472

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Mexico City to San Diego that are best for you.

Fly from

Mexico City

Fly to

San Diego

Route

Depart

Return

Price

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Sat 10/11

12:10 pm-6:15 pm

1 stop7h 05m

San Diego

Tue 10/14

8:10 am-5:05 pm

1 stop7h 55m

$377

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Fri 10/10

12:10 pm-6:15 pm

1 stop7h 05m

San Diego

Fri 10/17

8:10 am-5:05 pm

1 stop7h 55m

$443

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Fri 10/17

12:10 pm-6:15 pm

1 stop7h 05m

San Diego

Fri 10/24

8:10 am-5:05 pm

1 stop7h 55m

$472

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Thu 1/15

11:00 am-3:29 pm

1 stop6h 29m

$217

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Fri 10/10

12:10 pm-6:15 pm

1 stop7h 05m

$244

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Mon 1/5

6:05 am-7:36 pm

2 stops15h 31m

$262

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Sat 11/1

10:45 am-4:34 pm

1 stop6h 49m

$266

Mexico CitySan Diego

TLC - SAN

TLCSAN

Mexico City Toluca Intl

Thu 10/9

12:10 pm-6:15 pm

1 stop7h 05m

$283

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Mexico City to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to San Diego

What is the cheapest month to book a flight from Mexico City to San Diego?

Currently, August is the cheapest month in which you can book a flight from Mexico City to San Diego (average of $286). Flying from Mexico City to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Mexico City to San Diego that include hotel bookings?

    Yes. In addition to deals on Mexico City to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to San Diego.

  • Can I find deals for business class flights from Mexico City to San Diego?

    Yes. Cheapflights offers flight deals from Mexico City to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Mexico City to San Diego (average of $286). Flying from Mexico City to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine

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