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$241+ Cheap flights from Santa Fe to San Diego (SAF - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — SAN
May 23 — May 301
Sat 5/23
Sat 5/30
1 adult, Economy
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Cheap flight deals from Santa Fe to San Diego

Cheapest flights from Santa Fe to San Diego
Explore the most affordable flight options available from Santa Fe to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.

This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:30 pm
SAF
-
SAN
1 stop4h 25m
American Airlines
Tue 5/129:28 am
SAN
-
SAF
1 stop4h 27m
American Airlines
Deal found 4/21$320
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:30 pm
SAF
-
SAN
1 stop4h 25m
American Airlines
Wed 5/139:28 am
SAN
-
SAF
1 stop4h 27m
American Airlines
Deal found 4/21$321
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:42 pm
SAF
-
SAN
1 stop3h 52m
American Airlines
Tue 7/712:45 pm
SAN
-
SAF
1 stop4h 48m
American Airlines
Deal found 4/23$354
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 pm
SAF
-
SAN
1 stop5h 25m
United Airlines
Tue 6/96:35 am
SAN
-
SAF
1 stop5h 12m
United Airlines
Deal found 4/20$393
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:38 pm
SAF
-
SAN
1 stop3h 56m
American Airlines
Tue 6/3012:45 pm
SAN
-
SAF
1 stop4h 48m
American Airlines
Deal found 4/22$394
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:38 pm
SAF
-
SAN
1 stop3h 56m
American Airlines
Tue 6/912:45 pm
SAN
-
SAF
1 stop4h 48m
American Airlines
Deal found 4/23$400
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:25 pm
SAF
-
SAN
1 stop4h 03m
American Airlines
Sun 5/2412:45 pm
SAN
-
SAF
1 stop5h 03m
American Airlines
Deal found 4/19$410
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:30 pm
SAF
-
SAN
1 stop4h 25m
American Airlines
Sun 5/39:28 am
SAN
-
SAF
1 stop4h 27m
American Airlines
Deal found 4/22$412
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:49 pm
SAF
-
SAN
1 stop5h 27m
United Airlines
Tue 5/128:54 am
SAN
-
SAF
1 stop4h 56m
United Airlines
Deal found 4/23$446
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:31 pm
SAF
-
SAN
1 stop7h 45m
United Airlines
Wed 5/136:32 am
SAN
-
SAF
1 stop7h 18m
United Airlines
Deal found 4/21$448
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:38 pm
SAF
-
SAN
1 stop3h 56m
American Airlines
Sun 5/319:47 am
SAN
-
SAF
1 stop8h 01m
American Airlines
Deal found 4/20$468

Find flight deals from Santa Fe to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$320
(United Airlines)

One-way from

$241
(United Airlines)

Popular in

May

Cheapest in

August

Average price

$327
Provider with most accurate pricing for Santa Fe-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Fe-San Diego flights.
Search Deals
From Santa Fe to San Diego
Search Deals
One-way flight from Santa Fe to San Diego
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Santa Fe to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santa FeSan Diego

SAF - SAN

SAFSAN

Santa Fe

Wed 5/6

5:49 pm-10:16 pm

1 stop5h 27m

San Diego

Sun 5/10

6:32 am-2:50 pm

1 stop7h 18m

$320

Santa FeSan Diego

SAF - SAN

SAFSAN

Santa Fe

Thu 5/7

3:31 pm-10:16 pm

1 stop7h 45m

San Diego

Wed 5/13

6:32 am-2:50 pm

1 stop7h 18m

$448

Santa FeSan Diego

SAF - SAN

SAFSAN

Santa Fe

Thu 5/14

5:49 pm-10:16 pm

1 stop5h 27m

San Diego

Wed 5/20

4:26 pm-9:44 am

2 stops16h 18m

$510

Santa FeSan Diego

SAF - SAN

SAFSAN

Santa Fe

Thu 5/14

3:31 pm-10:16 pm

1 stop7h 45m

San Diego

Sat 5/23

6:27 pm-9:44 am

2 stops14h 17m

$510

Santa FeSan Diego

SAF - SAN

SAFSAN

Santa Fe

Fri 5/8

3:31 pm-10:16 pm

1 stop7h 45m

San Diego

Tue 5/12

4:26 pm-9:24 am

2 stops15h 58m

$514

Santa FeSan Diego

SAF - SAN

SAFSAN

Santa Fe

Sat 5/9

3:31 pm-9:12 pm

1 stop6h 41m

San Diego

Tue 5/12

6:26 pm-9:24 am

2 stops13h 58m

$515

Santa FeSan Diego

SAF - SAN

SAFSAN

Santa Fe

Thu 6/4

6:00 pm-10:25 pm

1 stop5h 25m

San Diego

Tue 6/9

4:09 pm-9:44 am

2 stops16h 35m

$515

Santa FeSan Diego

SAF - SAN

SAFSAN

Santa Fe

Thu 5/14

5:49 pm-10:16 pm

1 stop5h 27m

San Diego

Fri 5/22

6:55 pm-9:44 am

1 stop13h 49m

$520

Santa FeSan Diego

SAF - SAN

SAFSAN

Santa Fe

Sat 5/16

1:19 pm-5:19 pm

1 stop5h 00m

San Diego

Fri 5/22

6:55 pm-9:44 am

1 stop13h 49m

$520

Santa FeSan Diego

SAF - SAN

SAFSAN

Santa Fe

Tue 5/5

10:25 am-2:56 pm

1 stop5h 31m

San Diego

Fri 5/8

6:32 am-2:50 pm

1 stop7h 18m

$540

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/20

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Santa Fe to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Fe to San Diego in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Fe-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Fe-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Fe-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Fe-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Fe-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Fe to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to San Diego

How much does it cost to fly round-trip from Santa Fe to San Diego?

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 23, 2026.
Read through reviews of airlines operating flights from Santa Fe to San Diego, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,637 reviews

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
9,637 reviews
United Airlines
7.4
Good
9,637 reviews

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.1
Good
11,659 reviews
United Airlines
7.4
Good
9,637 reviews

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Fe to San Diego?

    Departing from Santa Fe to San Diego will take you 5h 27m. Santa Fe and San Diego are separated by a distance of 665 mi.

  • What are the cheapest airlines flying from Santa Fe to San Diego round-trip?

    American Airlines, at $244, was found to be the cheapest airline from Santa Fe to San Diego. An alternate airline flying to your destination would be United Airlines. You may be able to fly from Santa Fe to San Diego for 38% less than the average price by searching for these airlines.

  • Can I find deals for flights from Santa Fe to San Diego that include hotel bookings?

    Yes. In addition to deals on Santa Fe to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to San Diego.

  • Can I find deals for business class flights from Santa Fe to San Diego?

    Yes. Cheapflights offers flight deals from Santa Fe to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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Top 2 airlines flying from Santa Fe to San Diego

Discover the top 2 airlines that operate flights from Santa Fe to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$244Average$406FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$244Average$349FlexibilityNo cancel feeOn-time71%

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