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$109+ Cheap flights from Buffalo to San Diego (BUF - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SAN
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheapflights Tip: The best prices from Buffalo to San Diego are usually found in October or September, booked 54 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from Buffalo to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$217
(JetBlue)

One-way from

$109
(Priceline)

Popular in

December

Cheapest in

October

Average price

$351
Provider with most accurate pricing for Buffalo-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-San Diego flights.
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From Buffalo to San Diego
Search Deals
One-way flight from Buffalo to San Diego
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Buffalo to San Diego

Cheapest flights from Buffalo to San Diego
Explore the most affordable flight options available from Buffalo to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This JetBlue deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:15 pmBUF - SAN
1 stop10h 36mJetBlue
Mon 11/179:05 pmSAN - BUF
1 stop9h 15mJetBlue
Deal found 10/27$217
This JetBlue deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:15 pmBUF - SAN
1 stop10h 36mJetBlue
Sat 11/159:05 pmSAN - BUF
1 stop11h 14mJetBlue
Deal found 10/27$254
This Trip.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:15 pmBUF - SAN
1 stop10h 36mJetBlue
Sun 11/169:05 pmSAN - BUF
1 stop9h 15mJetBlue
Deal found 10/28$260
This Priceline deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:18 pmBUF - SAN
1 stop9h 53mJetBlue
Tue 12/98:31 pmSAN - BUF
1 stop11h 24mJetBlue
Deal found 10/27$281
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:34 amBUF - SAN
1 stop10h 25mAmerican Airlines
Sat 11/1510:49 pmSAN - BUF
1 stop9h 18mAmerican Airlines
Deal found 10/27$303
This JetBlue deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:15 pmBUF - SAN
1 stop10h 36mJetBlue
Tue 11/189:05 pmSAN - BUF
1 stop11h 14mJetBlue
Deal found 10/29$306
This JetBlue deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:18 pmBUF - SAN
1 stop9h 53mJetBlue
Wed 12/108:34 pmSAN - BUF
1 stop11h 21mJetBlue
Deal found 10/29$318
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:25 pmBUF - SAN
1 stop8h 18mDelta
Sun 11/1610:00 pmSAN - BUF
1 stop7h 34mDelta
Deal found 10/27$323
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:40 amBUF - SAN
1 stop9h 35mAmerican Airlines
Wed 11/196:15 amSAN - BUF
1 stop7h 11mAmerican Airlines
Deal found 10/27$335
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1511:54 amBUF - SAN
2 stops9h 30mAmerican Airlines
Tue 11/1812:43 pmSAN - BUF
1 stop6h 56mAmerican Airlines
Deal found 10/27$340

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

Fly from

Buffalo

Fly to

San Diego

Route

Depart

Return

Price

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 1/27

7:00 am-2:10 pm

1 stop10h 10m

San Diego

Sat 1/31

9:00 pm-9:04 am

1 stop9h 04m

$217

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Sat 11/15

12:15 pm-7:51 pm

1 stop10h 36m

San Diego

Tue 11/18

9:05 pm-9:20 am

1 stop9h 15m

$306

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 12/3

7:05 am-12:47 pm

1 stop8h 42m

San Diego

Wed 12/10

8:34 pm-10:55 am

1 stop11h 21m

$318

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 11/11

6:12 am-10:25 am

1 stop7h 13m

San Diego

Sat 11/15

10:00 pm-8:34 am

1 stop7h 34m

$323

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Sat 11/15

1:11 pm-6:30 pm

1 stop8h 19m

San Diego

Sun 11/16

9:50 pm-11:00 am

1 stop10h 10m

$323

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Fri 11/14

6:25 pm-11:43 pm

1 stop8h 18m

San Diego

Sun 11/16

10:00 pm-8:34 am

1 stop7h 34m

$323

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 3/5

12:45 pm-7:34 pm

1 stop9h 49m

San Diego

Mon 3/9

8:55 pm-8:29 am

1 stop8h 34m

$327

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 12/3

8:05 am-3:15 pm

1 stop10h 10m

San Diego

Wed 12/10

8:40 am-8:40 pm

2 stops9h 00m

$358

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Sat 12/20

5:35 pm-10:51 pm

1 stop8h 16m

San Diego

Sat 1/17

10:52 am-8:29 pm

1 stop6h 37m

$363

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 12/4

12:18 pm-7:11 pm

1 stop9h 53m

$109

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 21 results
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Compare providers for flights from Buffalo to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to San Diego in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-San Diego flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-San Diego flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-San Diego flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to San Diego

How far ahead should I book a flight from Buffalo to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to San Diego. Price data was last updated on October 24, 2025.

Booking 53 days in advance of your planned departure date is, on average, the best time to get cheap flights from Buffalo to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Buffalo to San Diego?

Currently, June is the cheapest month in which you can book a flight from Buffalo to San Diego (average of $99). Flying from Buffalo to San Diego in December is currently the most expensive (average of $283). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SAN?

Find hourly flight availability from Buffalo to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

When flying from Buffalo to San Diego, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 27% versus a flight in the morning.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated October 29, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Buffalo to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
7,992 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,999 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
JetBlue
7.2
Good
2,907 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to San Diego?

    Airlines like JetBlue and Delta fly from Buffalo to San Diego in about 7h 13m. The time it takes to get you to your destination can typically vary by up to 2h 57m. The distance between Buffalo and San Diego is about 2191 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to San Diego round-trip?

    Cheapflights users have booked flights from Buffalo to San Diego round-trip from $99. Other airlines that can offer you cheap pricing are JetBlue, from $256, and American Airlines, from $256. Users have found that Frontier is 76% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Buffalo to San Diego one-way?

    The cheapest airlines for a one-way flight from Buffalo to San Diego are JetBlue ($109), Frontier ($136), and Delta ($161).

  • Can I find deals for flights from Buffalo to San Diego that include hotel bookings?

    Yes. In addition to deals on Buffalo to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to San Diego.

  • Can I find deals for business class flights from Buffalo to San Diego?

    Yes. Cheapflights offers flight deals from Buffalo to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to San Diego?

    Currently, June is the cheapest month in which you can book a flight from Buffalo to San Diego (average of $99). Flying from Buffalo to San Diego in December is currently the most expensive (average of $283). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
National City

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Alternative routes for Buffalo to San Diego

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Top 6 airlines flying from Buffalo to San Diego

Discover the top 6 airlines that operate flights from Buffalo to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$99Average$285FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$256Average$328FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$256Average$408FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$279Average$469FlexibilityNo cancel feeOn-time63%
DeltaCheapest$296Average$393FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$331Average$502FlexibilityNo cancel feeOn-time69%

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