San Diego

$122+ Cheap flights from Buffalo to San Diego (BUF - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SAN
oct. 11 — oct. 181
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Cheapflights Tip: The best prices from Buffalo to San Diego are usually found in November or January, booked 69 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from Buffalo to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$227
(Southwest)

One-way from

$122
(American Airlines)

Popular in

December

Cheapest in

November

Average price

$402
From Buffalo to San Diego
One-way flight from Buffalo to San Diego
Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from Buffalo to San Diego

Cheapest flights from Buffalo to San Diego
Explore the most affordable flight options available from Buffalo to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/15:05 pmBUF - SAN
1 stop6h 55mSouthwest
jue. 11/61:35 pmSAN - BUF
1 stop7h 05mSouthwest
Deal found 9/11$227
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/1510:09 amBUF - SAN
1 stop7h 06mAmerican Airlines
mar. 11/186:15 amSAN - BUF
1 stop6h 57mAmerican Airlines
Deal found 9/10$243
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/156:00 amBUF - SAN
1 stop8h 14mAmerican Airlines
sáb. 10/2510:45 pmSAN - BUF
1 stop8h 55mAmerican Airlines
Deal found 9/10$270
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2011:35 amBUF - SAN
1 stop10h 24mAmerican Airlines
lun. 11/2410:23 pmSAN - BUF
1 stop9h 39mAmerican Airlines
Deal found 9/9$277
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/87:40 amBUF - SAN
2 stops10h 36mAmerican Airlines
mié. 11/1210:09 amSAN - BUF
2 stops10h 27mAmerican Airlines
Deal found 9/10$280
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/136:14 amBUF - SAN
1 stop9h 10mAmerican Airlines
mar. 10/216:20 amSAN - BUF
1 stop8h 58mAmerican Airlines
Deal found 9/10$289
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/45:34 amBUF - SAN
1 stop9h 09mAmerican Airlines
dom. 11/96:15 amSAN - BUF
1 stop7h 02mAmerican Airlines
Deal found 9/11$290
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/97:40 amBUF - SAN
1 stop9h 35mAmerican Airlines
mié. 11/1210:23 pmSAN - BUF
1 stop9h 39mAmerican Airlines
Deal found 9/10$291
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/55:47 pmBUF - SAN
1 stop7h 36mDelta
dom. 12/711:30 amSAN - BUF
1 stop8h 27mDelta
Deal found 9/11$297
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/167:14 pmBUF - SAN
2 stops17h 43mFrontier
lun. 10/206:41 amSAN - BUF
1 stop6h 48mFrontier
Deal found 9/10$300

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

Fly from

Buffalo

Fly to

San Diego

Route

Depart

Return

Price

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

jue. 1/15

5:50 am-10:35 am

1 stop7h 45m

San Diego

mié. 1/21

9:40 am-10:00 pm

1 stop9h 20m

$227

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

mar. 3/3

6:20 am-10:50 am

1 stop7h 30m

San Diego

mié. 3/4

7:05 am-5:05 pm

1 stop7h 00m

$235

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

mar. 2/17

5:50 am-10:35 am

1 stop7h 45m

San Diego

jue. 2/19

9:45 pm-8:05 am

1 stop7h 20m

$275

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

mar. 3/3

6:00 am-1:18 pm

1 stop10h 18m

San Diego

mié. 3/4

6:15 am-5:07 pm

1 stop7h 52m

$297

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

vie. 12/5

5:47 pm-10:23 pm

1 stop7h 36m

San Diego

dom. 12/7

10:00 pm-8:34 am

1 stop7h 34m

$297

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

dom. 10/26

6:20 am-10:34 am

1 stop7h 14m

San Diego

dom. 11/2

10:30 pm-11:01 am

1 stop9h 31m

$297

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

vie. 10/17

3:57 pm-11:47 pm

1 stop10h 50m

San Diego

lun. 10/20

10:20 pm-8:23 am

1 stop7h 03m

$316

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

vie. 12/26

6:00 am-3:10 pm

2 stops12h 10m

San Diego

mar. 1/6

9:40 am-10:00 pm

1 stop9h 20m

$341

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

mar. 3/3

5:20 pm-11:43 pm

1 stop9h 23m

San Diego

mié. 3/4

8:01 pm-10:42 am

2 stops11h 41m

$348

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

mar. 10/21

1:57 pm-12:15 am

2 stops13h 18m

San Diego

mar. 10/28

7:50 pm-9:48 am

2 stops10h 58m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 16 results
1
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Best time to book a flight from Buffalo to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to San Diego

How far ahead should I book a flight from Buffalo to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to San Diego. Price data was last updated on August 29, 2025.

Booking 69 days in advance of your planned departure date is, on average, the best time to get cheap flights from Buffalo to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Buffalo to San Diego?

Currently, August is the cheapest month in which you can book a flight from Buffalo to San Diego (average of $286). Flying from Buffalo to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SAN?

Find hourly flight availability from Buffalo to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

When flying from Buffalo to San Diego, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 28% versus a flight in the morning.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated septiembre 11, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Buffalo to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
8.0
Very good

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Buffalo to San Diego?

    Airlines like Southwest and Delta fly from Buffalo to San Diego in about 7h 45m. The time it takes to get you to your destination can typically vary by up to 2h 33m. The distance between Buffalo and San Diego is about 2191 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to San Diego round-trip?

    Cheapflights users have booked flights from Buffalo to San Diego round-trip from $99. Other airlines that can offer you cheap pricing are American Airlines, from $250, and JetBlue, from $259. Users have found that Frontier is 77% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Buffalo to San Diego one-way?

    The cheapest airlines for a one-way flight from Buffalo to San Diego are American Airlines ($122), Frontier ($140), and Delta ($149).

  • Can I find deals for flights from Buffalo to San Diego that include hotel bookings?

    Yes. In addition to deals on Buffalo to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to San Diego.

  • Can I find deals for business class flights from Buffalo to San Diego?

    Yes. Cheapflights offers flight deals from Buffalo to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to San Diego (average of $286). Flying from Buffalo to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Buffalo to San Diego

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Buffalo to San Diego

Discover the top 6 airlines that operate flights from Buffalo to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$99Average$275FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$250Average$416FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$259Average$339FlexibilityNo cancel feeOn-time62%
DeltaCheapest$296Average$395FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$340Average$513FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$346Average$459FlexibilityNo cancel feeOn-time63%

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