San Diego

$145+ Cheap flights from Buffalo to San Diego (BUF - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SAN
Apr 15 — Apr 221
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Cheap flight deals from Buffalo to San Diego

Cheapest flights from Buffalo to San Diego
Explore the most affordable flight options available from Buffalo to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.

This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:00 am
BUF
-
SAN
1 stop8h 14m
American Airlines
Sat 5/161:31 pm
SAN
-
BUF
1 stop7h 19m
American Airlines
Deal found 3/13$291
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:02 am
BUF
-
SAN
2 stops9h 17m
United Airlines
Sat 5/1610:40 pm
SAN
-
BUF
1 stop8h 01m
United Airlines
Deal found 3/12$296
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:10 pm
BUF
-
SAN
2 stops9h 35m
Southwest
Tue 5/127:40 pm
SAN
-
BUF
2 stops9h 10m
Southwest
Deal found 3/11$301
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:10 pm
BUF
-
SAN
1 stop8h 45m
Southwest
Sun 5/102:10 pm
SAN
-
BUF
1 stop6h 55m
Southwest
Deal found 3/13$314
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:31 am
BUF
-
SAN
2 stops9h 57m
American Airlines
Tue 5/1212:17 pm
SAN
-
BUF
1 stop8h 02m
American Airlines
Deal found 3/12$316
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:05 am
BUF
-
SAN
1 stop7h 39m
Delta
Sat 5/210:25 pm
SAN
-
BUF
1 stop9h 45m
Delta
Deal found 3/15$317
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:00 am
BUF
-
SAN
1 stop9h 17m
American Airlines
Sat 4/1810:30 pm
SAN
-
BUF
1 stop8h 48m
American Airlines
Deal found 3/14$318
This JetBlue deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:25 pm
BUF
-
SAN
1 stop10h 39m
JetBlue
Wed 5/68:30 pm
SAN
-
BUF
1 stop10h 09m
JetBlue
Deal found 3/12$319
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:00 pm
BUF
-
SAN
1 stop9h 00m
Southwest
Wed 5/67:40 pm
SAN
-
BUF
2 stops9h 10m
Southwest
Deal found 3/15$325

Find flight deals from Buffalo to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$291
(American Airlines)

One-way from

$106
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$435
Provider with most accurate pricing for Buffalo-San Diego flight deals.
Provider most trusted by Cheapflights users for Buffalo-San Diego flights.
From Buffalo to San Diego
One-way flight from Buffalo to San Diego
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 4/14

3:10 pm-9:30 pm

2 stops9h 20m

San Diego

Wed 5/13

8:30 am-9:45 pm

1 stop10h 15m

$296
Quickest round-trip

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 4/28

8:56 am-2:20 pm

1 stop8h 24m

San Diego

Wed 4/29

10:10 pm-8:16 am

1 stop7h 06m

$317

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 5/5

12:25 pm-8:04 pm

1 stop10h 39m

San Diego

Wed 5/6

8:30 pm-9:39 am

1 stop10h 09m

$319

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 4/23

12:40 pm-7:00 pm

1 stop9h 20m

San Diego

Sat 4/25

7:40 am-8:40 pm

1 stop10h 00m

$320

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 4/28

4:59 pm-11:25 pm

1 stop9h 26m

San Diego

Fri 5/1

9:45 pm-11:01 am

1 stop10h 16m

$337

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 4/22

1:52 pm-8:12 pm

2 stops9h 20m

San Diego

Mon 4/27

10:30 pm-10:10 am

1 stop8h 40m

$342

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Sun 5/10

5:55 pm-10:39 pm

1 stop7h 44m

San Diego

Fri 5/15

8:45 pm-9:41 am

2 stops9h 56m

$342

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 4/9

5:20 pm-10:00 pm

1 stop7h 40m

San Diego

Thu 4/16

10:40 pm-10:15 am

1 stop8h 35m

$343

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 4/22

1:10 pm-7:35 pm

2 stops9h 25m

San Diego

Mon 4/27

9:35 pm-10:20 am

2 stops9h 45m

$364

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 5/14

5:20 pm-10:00 pm

1 stop7h 40m

San Diego

Sun 5/17

10:40 pm-10:15 am

1 stop8h 35m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Compare providers for flights from Buffalo to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to San Diego in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to San Diego

How far ahead should I book a flight from Buffalo to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to San Diego. Price data was last updated on March 13, 2026.

Booking 53 days in advance of your planned departure date is, on average, the best time to get cheap flights from Buffalo to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Buffalo to San Diego?

Currently, June is the cheapest month in which you can book a flight from Buffalo to San Diego (average of $99). Flying from Buffalo to San Diego in July is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 16, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Buffalo to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Buffalo to San Diego?

    Airlines like American Airlines, United Airlines, and Southwest fly from Buffalo to San Diego in about 8h 14m. The time it takes to get you to your destination can typically vary by up to 1h 21m. The distance between Buffalo and San Diego is about 2191 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to San Diego round-trip?

    Cheapflights users have booked flights from Buffalo to San Diego round-trip from $99. Other airlines that can offer you cheap pricing are JetBlue, from $172, and Delta, from $218. Users have found that Frontier is 75% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Buffalo to San Diego one-way?

    The cheapest airlines for a one-way flight from Buffalo to San Diego are Frontier ($100), American Airlines ($121), and JetBlue ($134).

  • Can I find deals for flights from Buffalo to San Diego that include hotel bookings?

    Yes. In addition to deals on Buffalo to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to San Diego.

  • Can I find deals for business class flights from Buffalo to San Diego?

    Yes. Cheapflights offers flight deals from Buffalo to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to San Diego?

    Currently, June is the cheapest month in which you can book a flight from Buffalo to San Diego (average of $99). Flying from Buffalo to San Diego in July is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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Alternative routes for Buffalo to San Diego

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Buffalo to San Diego

Discover the top 6 airlines that operate flights from Buffalo to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$99Average$285FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$172Average$328FlexibilityNo cancel feeOn-time62%
DeltaCheapest$218Average$351FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$230Average$413FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$250Average$381FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$296Average$434FlexibilityNo cancel feeOn-time69%

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