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$312+ Cheap flights from Panama City (PTY) to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAT
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to San Antonio are usually found in October or April, booked 31 days in advance, depart on a Tuesday or Sunday and return on a Tuesday

Cheap flight deals from Panama City to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$515
(United Airlines)

One-way from

$312
(Delta)

Popular in

August

Cheapest in

October

Average price

$590
From Panama City Tocumen Intl to San Antonio
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One-way flight from Panama City Tocumen Intl to San Antonio
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Highest demand for flights based on searches. 8% potential increase in price ($54 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to San Antonio

Cheapest flights from Panama City to San Antonio
Explore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/64:41 pmPTY - SAT
1 stop23h 48mUnited Airlines
Tue 11/116:00 pmSAT - PTY
1 stop19h 45mUnited Airlines
Deal found 9/15$515
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/62:49 pmPTY - SAT
2 stops23h 12mAmerican Airlines
Tue 11/115:23 amSAT - PTY
1 stop7h 26mAmerican Airlines
Deal found 9/15$529
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/252:43 pmPTY - SAT
1 stop10h 16mAmerican Airlines
Fri 12/56:20 pmSAT - PTY
2 stops20h 17mAmerican Airlines
Deal found 9/14$550
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/153:30 pmPTY - SAT
1 stop28h 00mUnited Airlines
Mon 10/205:30 amSAT - PTY
1 stop13h 07mUnited Airlines
Deal found 9/14$558
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/258:55 amPTY - SAT
1 stop7h 34mUnited Airlines
Fri 12/57:35 pmSAT - PTY
1 stop23h 03mUnited Airlines
Deal found 9/14$559
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/153:15 pmPTY - SAT
2 stops24h 32mAmerican Airlines
Mon 10/206:24 pmSAT - PTY
2 stops19h 39mAmerican Airlines
Deal found 9/14$572
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/203:30 pmPTY - SAT
1 stop17h 08mUnited Airlines
Fri 10/247:16 amSAT - PTY
1 stop6h 58mUnited Airlines
Deal found 9/17$580
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/212:53 pmPTY - SAT
1 stop9h 33mAmerican Airlines
Sun 12/286:00 pmSAT - PTY
2 stops20h 54mAmerican Airlines
Deal found 9/15$587
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/223:15 pmPTY - SAT
2 stops18h 04mAmerican Airlines
Sun 10/266:39 pmSAT - PTY
2 stops19h 24mAmerican Airlines
Deal found 9/14$593
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/23:31 pmPTY - SAT
1 stop8h 24mAmerican Airlines
Fri 10/245:30 amSAT - PTY
1 stop8h 33mAmerican Airlines
Deal found 9/17$598
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/23:30 pmPTY - SAT
1 stop19h 19mUnited Airlines
Wed 10/87:38 pmSAT - PTY
1 stop22h 59mUnited Airlines
Deal found 9/15$601

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Panama City to San Antonio that are best for you.

Fly from

Panama City

Fly to

San Antonio

Route

Depart

Return

Price

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 11/6

2:49 pm-3:36 pm

2 stops25h 47m

San Antonio

Tue 11/11

4:30 pm-1:49 pm

2 stops20h 19m

$529

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Tue 11/25

2:43 pm-11:59 pm

1 stop10h 16m

San Antonio

Fri 12/5

6:20 pm-3:37 pm

2 stops20h 17m

$550

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 10/15

3:30 pm-7:30 pm

1 stop28h 00m

San Antonio

Mon 10/20

5:30 am-6:37 pm

1 stop13h 07m

$558

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 10/22

10:00 am-5:54 pm

1 stop7h 54m

San Antonio

Sun 10/26

7:30 pm-1:45 pm

1 stop18h 15m

$558

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Tue 11/25

8:55 am-3:29 pm

1 stop7h 34m

San Antonio

Fri 12/5

7:35 pm-7:38 pm

1 stop23h 03m

$559

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 10/15

3:15 pm-3:47 pm

2 stops24h 32m

San Antonio

Mon 10/20

6:24 pm-2:03 pm

2 stops19h 39m

$572

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 10/20

3:30 pm-8:38 am

1 stop17h 08m

San Antonio

Fri 10/24

7:16 am-2:14 pm

1 stop6h 58m

$580

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 10/22

3:15 pm-3:47 pm

2 stops24h 32m

San Antonio

Sun 10/26

5:30 am-2:03 pm

1 stop8h 33m

$593

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 10/20

3:15 pm-11:46 am

2 stops20h 31m

San Antonio

Fri 10/24

5:30 am-2:03 pm

1 stop8h 33m

$593

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 10/2

3:31 pm-11:55 pm

1 stop8h 24m

San Antonio

Fri 10/24

5:30 am-2:03 pm

1 stop8h 33m

$598

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 21 results
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Best time to book a flight from Panama City to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Antonio

How far ahead should I book a flight from Panama City to San Antonio?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to San Antonio. Price data was last updated on September 12, 2025.

The price you pay for your flight from Panama City to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 31 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $295). Flying from Panama City to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SAT?

Find hourly flight availability from Panama City to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

It’s optimal to fly from Panama City to San Antonio in the afternoon. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated September 17, 2025.
Read through reviews of airlines operating flights from Panama City to San Antonio, such as United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to San Antonio?

    A quick flight from Panama City to San Antonio can take about 25h 47m. American Airlines provides one of the quickest options available for as low as $529. Airlines will cover a distance of 1876 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Panama City to San Antonio round-trip?

    Currently priced at $479, United Airlines will fly you from Panama City to San Antonio and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. This flight start at 20% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Panama City to San Antonio one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $312. American Airlines flights start at $321 while deals on United Airlines start at $338 one-way.

  • Can I find deals for flights from Panama City to San Antonio that include hotel bookings?

    Yes. In addition to deals on Panama City to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Antonio.

  • Can I find deals for business class flights from Panama City to San Antonio?

    Yes. Cheapflights offers flight deals from Panama City to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to San Antonio?

    Currently, August is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $295). Flying from Panama City to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

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Top airline flying from Panama City to San Antonio

Discover the top airline that operate flights from Panama City to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$479Average$593FlexibilityNo cancel feeOn-time69%

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