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$300+ Cheap flights from Panama City (PTY) to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAT
Jan 9 — Jan 161
Fri 1/9
Fri 1/16
1 adult, Economy
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Cheap flight deals from Panama City to San Antonio

Cheapest flights from Panama City to San Antonio
Explore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 10, 2025.

This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:55 amPTY - SAT
1 stop24h 55mUnited Airlines
Sun 1/187:20 pmSAT - PTY
1 stop20h 47mUnited Airlines
Deal found 12/9$580
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:35 amPTY - SAT
1 stop7h 14mUnited Airlines
Mon 1/127:29 amSAT - PTY
1 stop11h 09mUnited Airlines
Deal found 12/10$612
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:55 amPTY - SAT
1 stop9h 52mUnited Airlines
Mon 1/124:04 pmSAT - PTY
1 stop21h 41mUnited Airlines
Deal found 12/9$618
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:55 pmPTY - SAT
2 stops23h 58mAmerican Airlines
Sun 1/186:01 pmSAT - PTY
2 stops18h 26mAmerican Airlines
Deal found 12/9$627
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:36 pmPTY - SAT
1 stop22h 00mMultiple Airlines
Sun 1/1110:35 amSAT - PTY
2 stops51h 20mMultiple Airlines
Deal found 12/7$628
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/184:55 pmPTY - SAT
2 stops19h 01mAmerican Airlines
Mon 1/126:01 pmSAT - PTY
2 stops18h 26mAmerican Airlines
Deal found 12/10$659
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:50 pmPTY - SAT
2 stops22h 08mAmerican Airlines
Mon 1/126:01 pmSAT - PTY
2 stops18h 26mAmerican Airlines
Deal found 12/8$674
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:43 pmPTY - SAT
2 stops20h 15mAmerican Airlines
Mon 1/125:10 amSAT - PTY
1 stop7h 17mAmerican Airlines
Deal found 12/10$687
This Mytrip deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1511:25 amPTY - SAT
2 stops13h 01mMultiple Airlines
Mon 1/1210:35 amSAT - PTY
3 stops37h 25mMultiple Airlines
Deal found 12/8$695
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:43 pmPTY - SAT
2 stops20h 15mAmerican Airlines
Thu 12/188:19 pmSAT - PTY
2 stops18h 35mAmerican Airlines
Deal found 12/10$698

Find flight deals from Panama City to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$516
(United Airlines)

One-way from

$300
(Kiwi.com)

Popular in

August

Cheapest in

April

Average price

$614
Provider with most accurate pricing for Panama City Tocumen Intl-San Antonio flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Antonio flights.
Search Deals
From Panama City Tocumen Intl to San Antonio
Search Deals
One-way flight from Panama City Tocumen Intl to San Antonio
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
Use the filters below to find and compare flights from Panama City to San Antonio that are best for you.

Fly from

Panama City

Fly to

San Antonio

Route

Depart

Return

Price

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 4/27

3:30 pm-10:41 am

1 stop19h 11m

San Antonio

Sun 5/3

6:02 pm-4:12 pm

1 stop22h 10m

$516

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 4/27

2:20 pm-12:14 am

1 stop9h 54m

San Antonio

Mon 5/4

5:30 am-12:55 pm

1 stop7h 25m

$516

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 4/1

7:55 am-9:10 pm

1 stop13h 15m

San Antonio

Mon 5/4

7:34 pm-2:14 pm

1 stop18h 40m

$516

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Tue 2/3

3:20 pm-12:38 am

1 stop10h 18m

San Antonio

Thu 5/14

5:30 am-12:55 pm

1 stop7h 25m

$516

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 2/26

4:41 pm-10:47 am

1 stop19h 06m

San Antonio

Tue 3/31

7:38 am-6:37 pm

1 stop10h 59m

$516

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 2/12

3:20 pm-12:34 am

1 stop10h 14m

San Antonio

Wed 5/6

5:30 am-12:55 pm

1 stop7h 25m

$516

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 2/18

4:41 pm-10:54 pm

1 stop7h 13m

San Antonio

Mon 2/23

7:20 pm-7:38 pm

1 stop23h 18m

$516

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 2/26

8:55 am-8:43 am

1 stop24h 48m

San Antonio

Wed 4/1

5:00 am-6:37 pm

1 stop13h 37m

$516

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Fri 1/30

2:55 am-9:40 am

2 stops31h 45m

$300

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Sat 3/14

7:55 am-11:15 pm

1 stop15h 20m

$338

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Showing 1-10 of 16 results
1
2

Compare providers for flights from Panama City to San Antonio

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Antonio in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-San Antonio flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-San Antonio flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-San Antonio flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-San Antonio flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Antonio

What is the cheapest month to book a flight from Panama City to San Antonio?

Currently, March is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $311). Flying from Panama City to San Antonio in January is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SAT?

Find hourly flight availability from Panama City to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 10, 2025.

It’s optimal to fly from Panama City to San Antonio in the afternoon. By choosing this option you can save up to 20% on the cost of your flight, compared to a flight in the evening.

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated December 10, 2025.
Read through reviews of airlines operating flights from Panama City to San Antonio, such as United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,092 reviews

Entertainment

7.1

Overall

7.4

Crew

8.1

Comfort

7.3

Food

6.6

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2025

AMS - EWR

It was good! The first 3/4 of the trip was uncomfortably cold. Only one option for lunch that I didn’t enjoy (vegetarian).
United Airlines
7.4
Good
9,092 reviews
United Airlines
7.4
Good
9,092 reviews

Entertainment

7.1

Overall

7.4

Crew

8.1

Comfort

7.3

Food

6.6

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2025

AMS - EWR

It was good! The first 3/4 of the trip was uncomfortably cold. Only one option for lunch that I didn’t enjoy (vegetarian).

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to San Antonio?

    A quick flight from Panama City to San Antonio can take about 9h 54m. United Airlines provides one of the quickest options available for as low as $516. Airlines will cover a distance of 1876 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Panama City to San Antonio round-trip?

    Currently priced at $524, United Airlines will fly you from Panama City to San Antonio and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. This flight start at 15% lower than the current average price 3 months from now.

  • Can I find deals for flights from Panama City to San Antonio that include hotel bookings?

    Yes. In addition to deals on Panama City to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Antonio.

  • Can I find deals for business class flights from Panama City to San Antonio?

    Yes. Cheapflights offers flight deals from Panama City to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to San Antonio?

    Currently, March is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $311). Flying from Panama City to San Antonio in January is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

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Top airline flying from Panama City to San Antonio

Discover the top airline that operate flights from Panama City to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$524Average$645FlexibilityNo cancel feeOn-time69%

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