HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Antonio

$260+ Cheap flights from Panama City (PTY) to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAT
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to San Antonio with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Panama City Tocumen Intl to San Antonio are usually found in April or March, booked 31 days in advance, depart on a Tuesday or Sunday and return on a Tuesday

Cheap flight deals from Panama City to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$516
(United Airlines)

One-way from

$260
(Kiwi.com)

Popular in

August

Cheapest in

April

Average price

$672
Provider with most accurate pricing for Panama City Tocumen Intl-San Antonio flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Antonio flights.
Search Deals
From Panama City Tocumen Intl to San Antonio
Search Deals
One-way flight from Panama City Tocumen Intl to San Antonio
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Panama City to San Antonio

Cheapest flights from Panama City to San Antonio
Explore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/262:43 pmPTY - SAT
1 stop10h 16mAmerican Airlines
Sat 11/295:23 amSAT - PTY
1 stop7h 20mAmerican Airlines
Deal found 10/25$589
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/118:55 amPTY - SAT
1 stop26h 48mUnited Airlines
Thu 11/2011:40 amSAT - PTY
1 stop6h 58mUnited Airlines
Deal found 10/25$601
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/48:55 amPTY - SAT
1 stop7h 34mUnited Airlines
Fri 1/307:40 amSAT - PTY
1 stop8h 27mUnited Airlines
Deal found 10/25$612
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:49 pmPTY - SAT
2 stops18h 35mAmerican Airlines
Thu 11/205:39 pmSAT - PTY
2 stops19h 04mAmerican Airlines
Deal found 10/25$615
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/42:49 pmPTY - SAT
2 stops22h 15mAmerican Airlines
Fri 1/305:10 amSAT - PTY
1 stop7h 17mAmerican Airlines
Deal found 10/25$618
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/34:41 pmPTY - SAT
1 stop27h 56mUnited Airlines
Sat 12/64:22 pmSAT - PTY
1 stop21h 23mUnited Airlines
Deal found 10/26$633
This Mytrip deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:55 amPTY - SAT
2 stops16h 37mMultiple Airlines
Thu 11/208:33 pmSAT - PTY
2 stops17h 22mMultiple Airlines
Deal found 10/25$634
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/292:21 pmPTY - SAT
1 stop9h 59mDelta
Sat 11/296:30 amSAT - PTY
1 stop12h 29mDelta
Deal found 10/27$640
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/24:41 pmPTY - SAT
1 stop7h 15mUnited Airlines
Sat 12/69:55 amSAT - PTY
1 stop27h 50mUnited Airlines
Deal found 10/26$655

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Panama City to San Antonio that are best for you.

Fly from

Panama City

Fly to

San Antonio

Route

Depart

Return

Price

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 2/18

4:41 pm-11:14 pm

1 stop7h 33m

San Antonio

Mon 2/23

7:37 pm-7:38 pm

1 stop23h 01m

$516

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 2/18

2:52 pm-11:00 am

2 stops21h 08m

San Antonio

Mon 2/23

5:45 pm-1:40 pm

2 stops18h 55m

$541

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Sun 2/1

4:41 pm-10:57 pm

1 stop7h 16m

San Antonio

Fri 2/20

4:12 pm-5:07 pm

1 stop23h 55m

$558

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Sun 2/1

4:46 pm-8:22 am

2 stops16h 36m

San Antonio

Fri 2/20

5:37 am-3:00 pm

1 stop8h 23m

$568

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 11/26

2:43 pm-11:59 pm

1 stop10h 16m

San Antonio

Sat 11/29

5:23 am-1:43 pm

1 stop7h 20m

$589

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Fri 11/21

11:25 am-10:55 am

2 stops24h 30m

$260

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 11/19

2:55 am-6:32 pm

2 stops16h 37m

$287

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 11/3

2:55 am-6:32 pm

2 stops16h 37m

$313

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 11/20

3:37 pm-11:16 pm

1 stop8h 39m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Compare providers for flights from Panama City to San Antonio

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Antonio in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-San Antonio flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-San Antonio flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-San Antonio flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-San Antonio flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Antonio

How far ahead should I book a flight from Panama City to San Antonio?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to San Antonio. Price data was last updated on October 24, 2025.

The price you pay for your flight from Panama City to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 31 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to San Antonio?

Currently, March is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $303). Flying from Panama City to San Antonio in January is currently the most expensive (average of $512). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SAT?

Find hourly flight availability from Panama City to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 27, 2025.

It’s optimal to fly from Panama City to San Antonio in the afternoon. By choosing this option you can save up to 20% on the cost of your flight, compared to a flight in the evening.

How much does it cost to fly round-trip from Panama City to San Antonio?

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated October 27, 2025.
Read through reviews of airlines operating flights from Panama City to San Antonio, such as United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,997 reviews

Boarding

7.7

Crew

8.1

Comfort

7.3

Food

6.6

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
8,997 reviews
United Airlines
7.4
Good
8,997 reviews

Boarding

7.7

Crew

8.1

Comfort

7.3

Food

6.6

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to San Antonio?

    A quick flight from Panama City to San Antonio can take about 7h 33m. United Airlines provides one of the quickest options available for as low as $516. Airlines will cover a distance of 1876 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Panama City to San Antonio round-trip?

    Currently priced at $524, United Airlines will fly you from Panama City to San Antonio and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. This flight start at 15% lower than the current average price 3 months from now.

  • Can I find deals for flights from Panama City to San Antonio that include hotel bookings?

    Yes. In addition to deals on Panama City to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Antonio.

  • Can I find deals for business class flights from Panama City to San Antonio?

    Yes. Cheapflights offers flight deals from Panama City to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to San Antonio?

    Currently, March is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $303). Flying from Panama City to San Antonio in January is currently the most expensive (average of $512). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Panama City to San Antonio

Discover the top airline that operate flights from Panama City to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$524Average$639FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.