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San Antonio

$272+ Cheap flights from Panama City (PTY) to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAT
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Panama City to San Antonio

Cheapest flights from Panama City to San Antonio
Explore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:10 pm
PTY
-
SAT
1 stop10h 49m
American Airlines
Tue 8/45:23 am
SAT
-
PTY
1 stop6h 47m
American Airlines
Deal found 1/19$547
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/710:00 am
PTY
-
SAT
1 stop9h 48m
United Airlines
Sat 4/117:40 am
SAT
-
PTY
1 stop8h 32m
United Airlines
Deal found 1/19$568
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/184:41 pm
PTY
-
SAT
1 stop17h 02m
United Airlines
Mon 2/2311:43 am
SAT
-
PTY
1 stop6h 55m
United Airlines
Deal found 1/19$581
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/164:41 pm
PTY
-
SAT
1 stop17h 02m
United Airlines
Sun 2/224:12 pm
SAT
-
PTY
1 stop21h 33m
United Airlines
Deal found 1/21$602
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/122:55 am
PTY
-
SAT
2 stops31h 35m
Multiple Airlines
Fri 2/205:04 pm
SAT
-
PTY
1 stop26h 30m
Multiple Airlines
Deal found 1/20$603
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/122:55 am
PTY
-
SAT
2 stops31h 35m
Multiple Airlines
Sat 2/2110:26 am
SAT
-
PTY
1 stop8h 53m
Multiple Airlines
Deal found 1/20$611
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/155:50 pm
PTY
-
SAT
2 stops40h 40m
Multiple Airlines
Fri 2/205:04 pm
SAT
-
PTY
1 stop26h 30m
Multiple Airlines
Deal found 1/20$613
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/155:50 pm
PTY
-
SAT
2 stops40h 40m
Multiple Airlines
Sat 2/2110:26 am
SAT
-
PTY
1 stop8h 53m
Multiple Airlines
Deal found 1/20$620
This KAYAK deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/144:41 pm
PTY
-
SAT
1 stop17h 02m
Copa Airlines
Tue 2/177:40 am
SAT
-
PTY
1 stop8h 27m
Copa Airlines
Deal found 1/20$622
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/182:40 pm
PTY
-
SAT
2 stops19h 53m
American Airlines
Mon 2/235:00 am
SAT
-
PTY
2 stops9h 15m
American Airlines
Deal found 1/19$629

Find flight deals from Panama City to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$568
(United Airlines)

One-way from

$272
(Kiwi.com)

Popular in

August

Cheapest in

April

Average price

$653
Provider with most accurate pricing for Panama City Tocumen Intl-San Antonio flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Antonio flights.
Search Deals
From Panama City Tocumen Intl to San Antonio
Search Deals
One-way flight from Panama City Tocumen Intl to San Antonio
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($27 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Panama City to San Antonio that are best for you.

Fly from

Panama City

Fly to

San Antonio

Route

Depart

Return

Price

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Tue 4/7

7:55 am-9:03 pm

1 stop13h 08m

San Antonio

Sat 4/11

7:40 am-2:14 pm

1 stop6h 34m

$568

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 2/18

4:41 pm-8:43 am

1 stop17h 02m

San Antonio

Mon 2/23

11:43 am-7:38 pm

1 stop6h 55m

$581

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 2/16

4:41 pm-8:43 am

1 stop17h 02m

San Antonio

Sun 2/22

4:12 pm-2:45 pm

1 stop21h 33m

$602

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Sun 2/15

5:50 pm-9:30 am

2 stops40h 40m

San Antonio

Sat 2/21

10:26 am-8:19 pm

1 stop8h 53m

$620

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 3/5

2:55 am-9:30 am

2 stops31h 35m

San Antonio

Fri 3/13

10:27 am-8:19 pm

1 stop9h 52m

$620

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 2/18

2:40 pm-1:06 pm

2 stops23h 26m

San Antonio

Mon 2/23

5:00 am-3:15 pm

2 stops9h 15m

$630

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 2/9

5:50 pm-11:52 pm

3 stops31h 02m

$272

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Sun 2/8

9:45 am-5:03 pm

3 stops32h 18m

$309

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Fri 2/6

2:55 am-11:52 pm

3 stops21h 57m

$319

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 3/5

2:55 am-8:08 pm

2 stops18h 13m

$332

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 14 results
1
2

Compare providers for flights from Panama City to San Antonio

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Antonio in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-San Antonio flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-San Antonio flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Antonio

What is the cheapest month to book a flight from Panama City to San Antonio?

Currently, March is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $303). Flying from Panama City to San Antonio in January is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to San Antonio?

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated January 21, 2026.
Read through reviews of airlines operating flights from Panama City to San Antonio, such as United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,191 reviews

Food

6.6

Overall

7.4

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,191 reviews
United Airlines
7.4
Good
9,191 reviews

Food

6.6

Overall

7.4

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to San Antonio?

    A quick flight from Panama City to San Antonio can take about 13h 08m. United Airlines provides one of the quickest options available for as low as $568. Airlines will cover a distance of 1876 mi.

  • What is the cheapest airline to fly from Panama City to San Antonio round-trip?

    Currently priced at $524, United Airlines will fly you from Panama City to San Antonio and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. This flight start at 16% lower than the current average price 3 months from now.

  • Can I find deals for flights from Panama City to San Antonio that include hotel bookings?

    Yes. In addition to deals on Panama City to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Antonio.

  • Can I find deals for business class flights from Panama City to San Antonio?

    Yes. Cheapflights offers flight deals from Panama City to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to San Antonio?

    Currently, March is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $303). Flying from Panama City to San Antonio in January is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

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Top airline flying from Panama City to San Antonio

Discover the top airline that operate flights from Panama City to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$524Average$650FlexibilityNo cancel feeOn-time69%

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