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$338+ Cheap flights from Panama City (PTY) to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAT
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to San Antonio are usually found in October or April, booked 31 days in advance, depart on a Tuesday or Sunday and return on a Tuesday

Cheap flight deals from Panama City to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$515
(Delta)

One-way from

$338
(United Airlines)

Popular in

August

Cheapest in

October

Average price

$692
From Panama City Tocumen Intl to San Antonio
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One-way flight from Panama City Tocumen Intl to San Antonio
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Highest demand for flights based on searches. 8% potential increase in price ($54 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Panama City to San Antonio

Cheapest flights from Panama City to San Antonio
Explore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/22:10 pmPTY - SAT
1 stop9h 49mDelta
Wed 10/85:14 amSAT - PTY
1 stop7h 42mDelta
Deal found 8/13$515
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1510:00 amPTY - SAT
1 stop12h 35mUnited Airlines
Thu 10/235:30 amSAT - PTY
1 stop13h 07mUnited Airlines
Deal found 8/13$524
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/153:15 pmPTY - SAT
2 stops21h 37mAmerican Airlines
Thu 10/232:26 pmSAT - PTY
2 stops23h 37mAmerican Airlines
Deal found 8/13$529
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/23:31 pmPTY - SAT
1 stop8h 24mAmerican Airlines
Fri 10/245:30 amSAT - PTY
1 stop8h 33mAmerican Airlines
Deal found 8/13$536
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/110:00 amPTY - SAT
1 stop22h 38mUnited Airlines
Sun 10/52:25 pmSAT - PTY
1 stop23h 49mUnited Airlines
Deal found 8/14$537
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/23:31 pmPTY - SAT
1 stop8h 24mAmerican Airlines
Wed 10/83:02 pmSAT - PTY
2 stops23h 01mAmerican Airlines
Deal found 8/13$540
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/33:31 pmPTY - SAT
1 stop8h 24mAmerican Airlines
Sat 10/255:20 amSAT - PTY
1 stop8h 43mAmerican Airlines
Deal found 8/14$557
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/102:05 pmPTY - SAT
1 stop9h 52mDelta
Wed 9/175:29 amSAT - PTY
1 stop7h 26mDelta
Deal found 8/14$558
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/253:31 pmPTY - SAT
2 stops17h 59mAmerican Airlines
Thu 10/25:29 amSAT - PTY
1 stop9h 02mAmerican Airlines
Deal found 8/14$572
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/11:45 pmPTY - SAT
2 stops24h 21mAmerican Airlines
Sun 10/55:29 amSAT - PTY
1 stop9h 02mAmerican Airlines
Deal found 8/14$584
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/101:45 pmPTY - SAT
2 stops21h 11mAmerican Airlines
Wed 9/176:49 pmSAT - PTY
2 stops19h 42mAmerican Airlines
Deal found 8/14$593

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Panama City to San Antonio that are best for you.

Fly from

Panama City

Fly to

San Antonio

Route

Depart

Return

Price

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 10/2

2:10 pm-11:59 pm

1 stop9h 49m

San Antonio

Wed 10/8

5:14 am-12:56 pm

1 stop7h 42m

$515

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 10/2

2:10 pm-10:19 pm

1 stop8h 09m

San Antonio

Tue 10/7

5:14 am-12:56 pm

1 stop7h 42m

$515

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 10/15

10:00 am-10:35 pm

1 stop12h 35m

San Antonio

Thu 10/23

5:30 am-6:37 pm

1 stop13h 07m

$524

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 10/15

3:15 pm-12:52 pm

2 stops21h 37m

San Antonio

Thu 10/23

2:26 pm-2:03 pm

2 stops23h 37m

$529

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 10/2

3:31 pm-11:55 pm

1 stop8h 24m

San Antonio

Fri 10/24

5:30 am-2:03 pm

1 stop8h 33m

$536

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 10/2

3:30 pm-7:30 pm

1 stop28h 00m

San Antonio

Wed 10/8

5:30 am-2:14 pm

1 stop8h 44m

$537

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 10/2

10:00 am-7:30 pm

1 stop9h 30m

San Antonio

Tue 10/7

7:16 am-6:37 pm

1 stop11h 21m

$537

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 10/1

10:00 am-8:38 am

1 stop22h 38m

San Antonio

Sun 10/5

7:38 pm-6:37 pm

1 stop22h 59m

$537

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 10/2

3:31 pm-3:53 pm

2 stops24h 22m

San Antonio

Wed 10/8

6:24 pm-2:03 pm

2 stops19h 39m

$540

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 10/2

3:31 pm-8:26 am

2 stops16h 55m

San Antonio

Tue 10/7

6:40 pm-2:03 pm

2 stops19h 23m

$540

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 17 results
1
2

Best time to book a flight from Panama City to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Antonio

How far ahead should I book a flight from Panama City to San Antonio?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to San Antonio. Price data was last updated on August 8, 2025.

The price you pay for your flight from Panama City to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 31 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $295). Flying from Panama City to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SAT?

Find hourly flight availability from Panama City to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

It’s optimal to fly from Panama City to San Antonio in the afternoon. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated August 14, 2025.
Read through reviews of airlines operating flights from Panama City to San Antonio, such as United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,916 reviews

Overall

7.4

Entertainment

7.1

Crew

8.1

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.
United Airlines
7.4
Good
8,916 reviews
United Airlines
7.4
Good
8,916 reviews

Overall

7.4

Entertainment

7.1

Crew

8.1

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Panama City to San Antonio round-trip?

    Currently priced at $469, United Airlines will fly you from Panama City to San Antonio and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. This flight start at 21% lower than the current average price 3 months from now.

  • Can I find deals for flights from Panama City to San Antonio that include hotel bookings?

    Yes. In addition to deals on Panama City to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Antonio.

  • Can I find deals for business class flights from Panama City to San Antonio?

    Yes. Cheapflights offers flight deals from Panama City to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to San Antonio?

    Currently, August is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $295). Flying from Panama City to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

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Top airline flying from Panama City to San Antonio

Discover the top airline that operate flights from Panama City to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$469Average$598FlexibilityNo cancel feeOn-time69%

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