$107+ Cheap flights from Missouri to San Antonio (SAT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAT
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to San Antonio
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Cheapest flights from Missouri to San AntonioExplore the most affordable flight options available from Missouri to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Missouri to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:58 pm -
1 stop23h 58m
Wed 12/910:52 pm -
1 stop14h 40m
Deal found 11/4![Frontier logo]()
$210
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:32 pm -
1 stop21h 29m
Wed 12/166:47 pm -
1 stop25h 09m
Deal found 11/1![Frontier logo]()
$218
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:29 pm -
1 stop21h 32m
Fri 12/118:47 pm -
1 stop22h 48m
Deal found 11/1![Frontier logo]()
$226
This Trip.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:58 pm -
1 stop22h 03m
Sat 12/510:52 pm -
1 stop14h 40m
Deal found 11/3![Frontier logo]()
$243
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:32 pm -
1 stop23h 30m
Sun 12/138:47 pm -
1 stop22h 48m
Deal found 11/1![Frontier logo]()
$249
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:32 pm -
1 stop23h 30m
Wed 12/166:47 pm -
1 stop25h 09m
Deal found 11/2![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:18 pm -
1 stop27h 07m
Sat 11/2110:11 pm -
1 stop18h 09m
Deal found 11/4![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:29 pm -
1 stop21h 32m
Sun 12/68:47 pm -
1 stop22h 48m
Deal found 11/3![Frontier logo]()
$257
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:29 pm -
1 stop21h 30m
Mon 12/78:47 pm -
1 stop22h 48m
Deal found 11/2![Frontier logo]()
$258
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:13 pm -
1 stop18h 06m
Mon 12/712:32 pm -
1 stop11h 40m
Deal found 11/3![Frontier logo]()
$258
This Trip.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:54 pm -
1 stop24h 08m
Thu 12/108:47 pm -
1 stop14h 10m
Deal found 11/4![Frontier logo]()
$259
This Trip.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:54 pm -
1 stop22h 07m
Fri 12/118:47 pm -
1 stop14h 10m
Deal found 11/2![Frontier logo]()
$261
Best flights from Missouri to San AntonioDiscover carefully curated flight deals from Missouri to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Missouri to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/55:40 pm -
Nonstop2h 00m
Mon 2/155:30 pm -
1 stop7h 00m
Deal found 10/31![Southwest logo]()
$270
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
1 stop5h 55m
Tue 11/246:30 am -
1 stop8h 19m
Deal found 10/31![Delta logo]()
$275
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:45 am -
2 stops7h 21m
Sat 12/127:30 am -
1 stop4h 16m
Deal found 11/2![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/47:57 pm -
1 stop4h 02m
Mon 1/117:00 am -
1 stop4h 31m
Deal found 10/31![American Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:55 am -
1 stop6h 15m
Sat 12/57:45 am -
Nonstop2h 05m
Deal found 11/3![Southwest logo]()
$315
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
1 stop5h 55m
Sun 11/225:30 am -
1 stop6h 45m
Deal found 10/31![Delta logo]()
$336
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2310:15 pm -
Nonstop2h 25m
Thu 12/244:30 pm -
1 stop6h 00m
Deal found 11/1![Southwest logo]()
$315
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/163:12 pm -
1 stop8h 02m
Tue 1/191:14 pm -
1 stop7h 16m
Deal found 11/4![United Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:28 am -
1 stop6h 22m
Thu 12/318:19 pm -
1 stop3h 37m
Deal found 11/2![American Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/162:05 pm -
Nonstop2h 20m
Fri 1/2212:55 pm -
1 stop4h 00m
Deal found 10/31![Southwest logo]()
$315
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/213:16 pm -
1 stop7h 52m
Mon 4/265:00 pm -
1 stop5h 58m
Deal found 11/2![United Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:57 pm -
1 stop4h 02m
Mon 12/288:19 pm -
1 stop3h 37m
Deal found 11/4![American Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:25 pm -
Nonstop2h 20m
Wed 12/306:50 pm -
1 stop6h 00m
Deal found 11/2![Southwest logo]()
$315
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
1 stop4h 51m
Sun 12/65:15 am -
1 stop4h 30m
Deal found 11/1![United Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/155:40 pm -
Nonstop2h 00m
Sun 1/179:50 am -
1 stop4h 50m
Deal found 11/2![Southwest logo]()
$331
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/313:10 pm -
1 stop7h 49m
Thu 1/711:50 am -
2 stops11h 40m
Deal found 11/2![United Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:20 pm -
1 stop7h 05m
Thu 12/316:35 am -
1 stop4h 30m
Deal found 11/4![Southwest logo]()
$336
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am -
1 stop4h 51m
Sun 12/65:15 am -
2 stops7h 07m
Deal found 10/31![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:55 am -
1 stop6h 15m
Mon 12/77:25 am -
Nonstop2h 10m
Deal found 11/2![Southwest logo]()
$337
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop6h 20m
Tue 12/88:45 am -
1 stop7h 29m
Deal found 11/2![United Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1212:42 pm -
1 stop6h 38m
Wed 12/167:30 am -
2 stops8h 43m
Deal found 11/2![United Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/265:40 pm -
Nonstop2h 00m
Mon 3/18:05 am -
Nonstop1h 55m
Deal found 11/4![Southwest logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:36 pm -
2 stops9h 28m
Mon 12/215:15 am -
1 stop4h 47m
Deal found 11/1![United Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:40 am -
Nonstop2h 15m
Sat 12/196:40 pm -
1 stop6h 15m
Deal found 11/4![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/318:30 am -
1 stop4h 51m
Tue 1/129:35 am -
2 stops12h 11m
Deal found 11/4![United Airlines logo]()
$380
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:00 am -
1 stop4h 38m
Thu 11/267:01 am -
2 stops8h 42m
Deal found 11/3![United Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2910:45 pm -
Nonstop2h 15m
Wed 12/27:25 am -
Nonstop2h 10m
Deal found 11/2![Southwest logo]()
$402
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/42:58 pm -
1 stop4h 41m
Mon 1/1111:50 am -
2 stops9h 54m
Deal found 10/31![United Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/165:00 am -
2 stops8h 13m
Fri 1/2211:50 am -
2 stops9h 47m
Deal found 10/31![United Airlines logo]()
$425
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/273:10 pm -
1 stop8h 07m
Wed 3/36:35 am -
1 stop7h 56m
Deal found 11/2![United Airlines logo]()
$448
Last-minute flights from Missouri to San AntonioDiscover last-minute flight deals from Missouri to San Antonio. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to San Antonio. Data last updated November 5, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:18 pm -
1 stop27h 07m
Sat 11/2110:11 pm -
1 stop18h 09m
Deal found 11/4![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:29 pm -
1 stop21h 30m
Mon 12/78:47 pm -
1 stop22h 48m
Deal found 11/2![Frontier logo]()
$258
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:58 pm -
1 stop23h 58m
Wed 12/910:52 pm -
1 stop14h 40m
Deal found 11/4![Frontier logo]()
$210
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:13 pm -
1 stop18h 06m
Mon 12/712:32 pm -
1 stop11h 40m
Deal found 11/3![Frontier logo]()
$258
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:29 pm -
1 stop21h 32m
Fri 12/118:47 pm -
1 stop22h 48m
Deal found 11/1![Frontier logo]()
$226
This Trip.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:58 pm -
1 stop22h 03m
Sat 12/510:52 pm -
1 stop14h 40m
Deal found 11/3![Frontier logo]()
$243
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:29 pm -
1 stop21h 32m
Sun 12/68:47 pm -
1 stop22h 48m
Deal found 11/3![Frontier logo]()
$257
This Trip.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:54 pm -
1 stop24h 08m
Thu 12/108:47 pm -
1 stop14h 10m
Deal found 11/4![Frontier logo]()
$259
This Trip.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:54 pm -
1 stop22h 07m
Fri 12/118:47 pm -
1 stop14h 10m
Deal found 11/2![Frontier logo]()
$261
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:32 pm -
1 stop23h 30m
Sun 12/138:47 pm -
1 stop22h 48m
Deal found 11/1![Frontier logo]()
$249
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:32 pm -
1 stop23h 30m
Wed 12/166:47 pm -
1 stop25h 09m
Deal found 11/2![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:32 pm -
1 stop21h 29m
Wed 12/166:47 pm -
1 stop25h 09m
Deal found 11/1![Frontier logo]()
$218
One-way flights from Missouri to San AntonioSearch for one-way flight options from Missouri to San Antonio. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Missouri to San Antonio. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:13 pm -
1 stop18h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Frontier logo]()
$107
This Trip.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:32 pm -
1 stop21h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$109
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:29 pm -
1 stop21h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Frontier logo]()
$119
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:15 pm -
1 stop28h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Frontier logo]()
$128
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:54 pm -
1 stop24h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$131
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:05 pm -
Nonstop2h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Southwest logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:54 pm -
1 stop22h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Frontier logo]()
$135
This Trip.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:45 pm -
1 stop17h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$136
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:26 pm -
1 stop4h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![United Airlines logo]()
$138
This Super.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:43 pm -
1 stop22h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$143
This Orbitz deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:20 pm -
1 stop17h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Frontier logo]()
$146
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:43 pm -
1 stop22h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$151
Find flight deals from Missouri to San Antonio
Keep the following information in mind while searching for Missouri to San Antonio flight deals. Data was last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $210 (CheapOair) |
One-way from | $107 (CheapOair) |
Popular in | August |
Cheapest in | January |
Average price | $467 |
Good round-trip deal | $305 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Missouri to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSan Antonio
STL Lambert-St Louis - SAT San Antonio
STLSAT
Lambert-St Louis
Tue 12/1
6:13 pm-12:42 pm
1 stop18h 29m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$108
Quickest round-trip
Kansas CitySan Antonio
MCI Kansas City - SAT San Antonio
MCISAT
Kansas City
Fri 12/18
6:05 pm-8:05 pm
Nonstop2h 00m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$133
St. LouisSan Antonio
STL Lambert-St Louis - SAT San Antonio
STLSAT
Lambert-St Louis
Fri 1/1
8:25 pm-10:45 pm
Nonstop2h 20m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$153
St. LouisSan Antonio
STL Lambert-St Louis - SAT San Antonio
STLSAT
Lambert-St Louis
Thu 12/17
9:50 pm-12:10 am
Nonstop2h 20m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$153
St. LouisSan Antonio
STL Lambert-St Louis - SAT San Antonio
STLSAT
Lambert-St Louis
Tue 11/24
10:15 pm-12:40 am
Nonstop2h 25m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$153
Kansas CitySan Antonio
MCI Kansas City - SAT San Antonio
MCISAT
Kansas City
Fri 11/20
8:29 pm-12:36 pm
1 stop16h 07m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$157
St. LouisSan Antonio
STL Lambert-St Louis - SAT San Antonio
STLSAT
Lambert-St Louis
Sat 12/5
12:36 pm-7:59 pm
1 stop7h 23m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$158
St. LouisSan Antonio
STL Lambert-St Louis - SAT San Antonio
STLSAT
Lambert-St Louis
Thu 11/26
5:00 am-12:08 pm
1 stop7h 08m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$158
Kansas CitySan Antonio
MCI Kansas City - SAT San Antonio
MCISAT
Kansas City
Sun 11/15
8:43 pm-7:25 pm
1 stop22h 42m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$182
SpringfieldSan Antonio
SGF Springfield-Branson - SAT San Antonio
SGFSAT
Springfield-Branson
Wed 11/25
7:36 pm-12:06 am
1 stop4h 30m
San Antonio
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$185
Showing 1-10 of 53 resultsSorted by cheapest first
Best time to book a flight from Missouri to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Missouri with our price prediction graph.
STL-SAT
MCI-SAT
SGF-SAT
COU-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to San Antonio
USMO-SAT
STL-SAT
MCI-SAT
SGF-SAT
COU-SAT
What is the cheapest month to book a flight from Missouri to San Antonio?
Currently, February is the cheapest month in which you can book a flight from Missouri to San Antonio (average of $336). Flying from Missouri to San Antonio in July is currently the most expensive (average of $464). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to SAT?
Find hourly flight availability from Missouri to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2026.
When flying from Missouri to San Antonio, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 26% versus a flight at noon.
Weekly flight availability from Missouri to San Antonio
Explore weekly flight availability from Missouri to San Antonio. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 5, 2026.
The most flights from USMO to SAT are scheduled on a Tuesday (3 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Missouri to San Antonio?
Airfare is below average for this route at the moment.
Missouri to San Antonio flights typically cost between $352 and $662 in December.The cheapest round-trip price found within the last 5 days was $210 on Frontier (Dec 2-Dec 9).
How far ahead should I book a flight from Missouri to San Antonio?
The best time to book flights from Missouri to San Antonio is 72 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Related info for your journey
Find useful and relevant information for your journey from Missouri to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Missouri to San Antonio
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Complete your trip
Complete your trip to San Antonio by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to San Antonio by cabin class
Find flights from Missouri to San Antonio, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and San Antonio flights
Browse other Missouri and San Antonio flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Missouri to San Antonio flights
Consider these flights traveling from Missouri to San Antonio.
Top 5 airlines flying from Missouri to San Antonio
Discover the top 5 airlines that operate flights from Missouri to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$111 | Average$270 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$186 | Average$304 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$196 | Average$361 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$240 | Average$434 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$275 | Average$406 | FlexibilityNo cancel fee | On-time63% |